Details for: DYRK1B
Associated with
Other Information
Genular Protein ID: 3222797585
Symbol: DYR1B_HUMAN
Name: Dual specificity tyrosine-phosphorylation-regulated kinase 1B
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9918863
Title: Cloning and characterization of DYRK1B, a novel member of the DYRK family of protein kinases.
PubMed ID: 9918863
PubMed ID: 10910078
Title: Mirk protein kinase is a mitogen-activated protein kinase substrate that mediates survival of colon cancer cells.
PubMed ID: 10910078
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11980910
Title: Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha.
PubMed ID: 11980910
PubMed ID: 14500717
Title: Serine/threonine kinase Mirk/Dyrk1B is an inhibitor of epithelial cell migration and is negatively regulated by the Met adaptor Ran-binding protein M.
PubMed ID: 14500717
PubMed ID: 14593110
Title: Phosphorylation of Ser640 in muscle glycogen synthase by DYRK family protein kinases.
PubMed ID: 14593110
PubMed ID: 22998443
Title: Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B.
PubMed ID: 22998443
DOI: 10.1021/jm301034u
PubMed ID: 24827035
Title: A form of the metabolic syndrome associated with mutations in DYRK1B.
PubMed ID: 24827035
PubMed ID: 33469661
Title: A DYRK1B-dependent pathway suppresses rDNA transcription in response to DNA damage.
PubMed ID: 33469661
DOI: 10.1093/nar/gkaa1290
PubMed ID: 32611815
Title: Screen identifies DYRK1B network as mediator of transcription repression on damaged chromatin.
PubMed ID: 32611815
PubMed ID: 17344846
Title: Patterns of somatic mutation in human cancer genomes.
PubMed ID: 17344846
DOI: 10.1038/nature05610
Sequence Information:
- Length: 629
- Mass: 69198
- Checksum: D7C354AC55943A8B
- Sequence:
MAVPPGHGPF SGFPGPQEHT QVLPDVRLLP RRLPLAFRDA TSAPLRKLSV DLIKTYKHIN EVYYAKKKRR AQQAPPQDSS NKKEKKVLNH GYDDDNHDYI VRSGERWLER YEIDSLIGKG SFGQVVKAYD HQTQELVAIK IIKNKKAFLN QAQIELRLLE LMNQHDTEMK YYIVHLKRHF MFRNHLCLVF ELLSYNLYDL LRNTHFRGVS LNLTRKLAQQ LCTALLFLAT PELSIIHCDL KPENILLCNP KRSAIKIVDF GSSCQLGQRI YQYIQSRFYR SPEVLLGTPY DLAIDMWSLG CILVEMHTGE PLFSGSNEVD QMNRIVEVLG IPPAAMLDQA PKARKYFERL PGGGWTLRRT KELRKDYQGP GTRRLQEVLG VQTGGPGGRR AGEPGHSPAD YLRFQDLVLR MLEYEPAARI SPLGALQHGF FRRTADEATN TGPAGSSAST SPAPLDTCPS SSTASSISSS GGSSGSSSDN RTYRYSNRYC GGPGPPITDC EMNSPQVPPS QPLRPWAGGD VPHKTHQAPA SASSLPGTGA QLPPQPRYLG RPPSPTSPPP PELMDVSLVG GPADCSPPHP APAPQHPAAS ALRTRMTGGR PPLPPPDDPA TLGPHLGLRG VPQSTAASS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.