Details for: CD3E

Gene ID: 916

Symbol: CD3E

Ensembl ID: ENSG00000198851

Description: CD3 epsilon subunit of T-cell receptor complex

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 89.1702
    Cell Significance Index: -13.8700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 62.4974
    Cell Significance Index: -25.3900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 58.2708
    Cell Significance Index: -14.7800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 51.1290
    Cell Significance Index: -26.3000
  • Cell Name: hepatic pit cell (CL2000054)
    Fold Change: 16.1485
    Cell Significance Index: 43.2600
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 11.4347
    Cell Significance Index: 34.8500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 11.2375
    Cell Significance Index: 394.8700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 10.9574
    Cell Significance Index: -13.5100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 10.4233
    Cell Significance Index: 306.1200
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 5.7888
    Cell Significance Index: -17.7800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 4.9143
    Cell Significance Index: 122.8500
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 4.2675
    Cell Significance Index: 42.7900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 3.8469
    Cell Significance Index: -15.1800
  • Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
    Fold Change: 2.0605
    Cell Significance Index: 15.3300
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: 1.9156
    Cell Significance Index: 16.7600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.9052
    Cell Significance Index: 41.2800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.7050
    Cell Significance Index: 77.2800
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 1.4834
    Cell Significance Index: 15.3800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.2385
    Cell Significance Index: 235.7000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.0512
    Cell Significance Index: 103.9900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.8308
    Cell Significance Index: 750.1400
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 0.7916
    Cell Significance Index: 8.2100
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 0.7024
    Cell Significance Index: 3.8300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4571
    Cell Significance Index: 74.3400
  • Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
    Fold Change: 0.4403
    Cell Significance Index: 3.4300
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 0.3467
    Cell Significance Index: 3.3800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3224
    Cell Significance Index: 35.0600
  • Cell Name: CD8-alpha alpha positive, gamma-delta intraepithelial T cell (CL0000802)
    Fold Change: 0.3190
    Cell Significance Index: 1.8500
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: 0.1972
    Cell Significance Index: 1.6800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0995
    Cell Significance Index: 6.8800
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: 0.0876
    Cell Significance Index: 0.7000
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 0.0622
    Cell Significance Index: 0.5300
  • Cell Name: natural T-regulatory cell (CL0000903)
    Fold Change: 0.0531
    Cell Significance Index: 0.5200
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: 0.0496
    Cell Significance Index: 0.8600
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: 0.0363
    Cell Significance Index: 0.3400
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: 0.0253
    Cell Significance Index: 0.2400
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 0.0041
    Cell Significance Index: 0.0600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0003
    Cell Significance Index: 0.0400
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: -0.0042
    Cell Significance Index: -0.0400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0069
    Cell Significance Index: -0.2000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0077
    Cell Significance Index: -14.5600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0096
    Cell Significance Index: -17.7500
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0121
    Cell Significance Index: -0.3100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0131
    Cell Significance Index: -17.7500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0150
    Cell Significance Index: -11.0800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0151
    Cell Significance Index: -11.4000
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -0.0224
    Cell Significance Index: -0.3100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0281
    Cell Significance Index: -1.4200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0291
    Cell Significance Index: -16.4100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0295
    Cell Significance Index: -16.1100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0333
    Cell Significance Index: -14.7200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0350
    Cell Significance Index: -1.1200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0378
    Cell Significance Index: -27.6800
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: -0.0411
    Cell Significance Index: -0.3800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0429
    Cell Significance Index: -15.4000
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0431
    Cell Significance Index: -1.7600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0433
    Cell Significance Index: -27.4800
  • Cell Name: blood cell (CL0000081)
    Fold Change: -0.0481
    Cell Significance Index: -0.4100
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0489
    Cell Significance Index: -0.8300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0521
    Cell Significance Index: -23.6400
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0627
    Cell Significance Index: -2.7300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0631
    Cell Significance Index: -18.1700
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.0652
    Cell Significance Index: -0.7700
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: -0.0676
    Cell Significance Index: -0.6100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0695
    Cell Significance Index: -13.7900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0763
    Cell Significance Index: -15.3000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0771
    Cell Significance Index: -1.6000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0793
    Cell Significance Index: -9.2400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0923
    Cell Significance Index: -1.9700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0936
    Cell Significance Index: -15.9900
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: -0.1062
    Cell Significance Index: -1.1300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1144
    Cell Significance Index: -15.7100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.1149
    Cell Significance Index: -20.7200
  • Cell Name: mature T cell (CL0002419)
    Fold Change: -0.1334
    Cell Significance Index: -0.9600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1373
    Cell Significance Index: -6.4600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1420
    Cell Significance Index: -16.2700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1457
    Cell Significance Index: -15.1700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1470
    Cell Significance Index: -18.8500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.1506
    Cell Significance Index: -9.0400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1614
    Cell Significance Index: -20.8500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.1642
    Cell Significance Index: -20.1900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1657
    Cell Significance Index: -10.1600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1755
    Cell Significance Index: -3.0100
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: -0.1861
    Cell Significance Index: -1.8800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1861
    Cell Significance Index: -19.0100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1884
    Cell Significance Index: -27.3900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2060
    Cell Significance Index: -14.5700
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: -0.2198
    Cell Significance Index: -2.2300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2295
    Cell Significance Index: -6.1400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2424
    Cell Significance Index: -16.3000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2443
    Cell Significance Index: -15.4000
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: -0.2445
    Cell Significance Index: -2.1100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2463
    Cell Significance Index: -18.9000
  • Cell Name: naive T cell (CL0000898)
    Fold Change: -0.2829
    Cell Significance Index: -2.5700
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.2847
    Cell Significance Index: -4.2900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2850
    Cell Significance Index: -21.2400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3343
    Cell Significance Index: -20.5500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.3449
    Cell Significance Index: -22.2500
  • Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
    Fold Change: -0.3495
    Cell Significance Index: -2.8300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.3558
    Cell Significance Index: -16.5900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** The CD3E gene is a member of the CD3 gene family, which consists of four subunits (CD3E, CD3C, CD3D, and CD3G) that form the TCR complex. The CD3E subunit is a transmembrane receptor protein tyrosine kinase that is involved in signal transduction and the regulation of gene expression. It is highly expressed in mature T-cells, including alpha-beta and gamma-delta T-cells, as well as in double negative T regulatory cells. The CD3E subunit is also expressed in other cell types, such as dendritic cells and endothelial cells. **Pathways and Functions** The CD3E subunit is involved in various signaling pathways, including: 1. **Calcium-mediated signaling**: The CD3E subunit plays a crucial role in calcium-mediated signaling, which is essential for T-cell activation and the regulation of gene expression. 2. **CD28 family costimulation**: The CD3E subunit is involved in costimulation by the CD28 family, which is necessary for optimal T-cell activation and proliferation. 3. **Apoptotic signaling pathway**: The CD3E subunit regulates the apoptotic signaling pathway, which is involved in the elimination of self-reactive T-cells and the maintenance of immune homeostasis. 4. **G-protein coupled receptor signaling pathway**: The CD3E subunit is also involved in G-protein coupled receptor signaling pathway, which is involved in the regulation of gene expression and cell-cell adhesion. The CD3E subunit has several functions, including: 1. **T-cell activation**: The CD3E subunit is involved in the activation of T-cells, which is necessary for the initiation of an immune response. 2. **T-cell proliferation**: The CD3E subunit regulates T-cell proliferation, which is essential for the expansion of T-cells in response to antigen presentation. 3. **Gene expression regulation**: The CD3E subunit regulates gene expression, including the expression of cytokines and chemokines that are involved in immune responses. 4. **Cell-cell adhesion**: The CD3E subunit is involved in cell-cell adhesion, which is necessary for the formation of the immunological synapse and the regulation of T-cell function. **Clinical Significance** Mutations or alterations in the CD3E gene can lead to various immune-related disorders, including: 1. **Immunodeficiency**: Impaired T-cell function due to mutations or alterations in the CD3E gene can lead to immunodeficiency, which increases the risk of infections and autoimmune diseases. 2. **Autoimmune diseases**: Abnormal T-cell function due to mutations or alterations in the CD3E gene can contribute to the development of autoimmune diseases, such as multiple sclerosis and type 1 diabetes. 3. **Cancer**: Impaired T-cell function due to mutations or alterations in the CD3E gene can contribute to the development of cancer, as T-cells play a crucial role in the elimination of cancer cells. In conclusion, the CD3E gene plays a crucial role in the adaptive immune system, and mutations or alterations in this gene can lead to various immune-related disorders. Further research is necessary to fully understand the functions and clinical significance of the CD3E gene.

Genular Protein ID: 4230133941

Symbol: CD3E_HUMAN

Name: T-cell surface glycoprotein CD3 epsilon chain

UniProtKB Accession Codes:

P07766 A8K997

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 4 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 DrugBank 10 DrugCentral 1 ELM 1 EMBL 12 EMDB 14 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 51 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 20 PDBsum 20 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 6 RefSeq 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3012357

Title: Isolation of cDNA clones encoding the 20K non-glycosylated polypeptide chain of the human T-cell receptor/T3 complex.

PubMed ID: 3012357

DOI: 10.1038/321431a0

PubMed ID: 3267235

Title: Human CD3-epsilon gene contains three miniexons and is transcribed from a non-TATA promoter.

PubMed ID: 3267235

DOI: 10.1073/pnas.85.21.8156

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2470098

Title: The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex.

PubMed ID: 2470098

DOI: 10.1073/pnas.86.9.3277

PubMed ID: 1387664

Title: Expression of cytoplasmic CD3 epsilon proteins in activated human adult natural killer (NK) cells and CD3 gamma, delta, epsilon complexes in fetal NK cells. Implications for the relationship of NK and T lymphocytes.

PubMed ID: 1387664

PubMed ID: 8490660

Title: Independent mutations of the human CD3-epsilon gene resulting in a T cell receptor/CD3 complex immunodeficiency.

PubMed ID: 8490660

DOI: 10.1038/ng0193-77

PubMed ID: 10384095

Title: The CD3 epsilon subunit of the TCR contains endocytosis signals.

PubMed ID: 10384095

PubMed ID: 12522270

Title: Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry.

PubMed ID: 12522270

DOI: 10.1073/pnas.2436191100

PubMed ID: 15144186

Title: Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.

PubMed ID: 15144186

DOI: 10.1021/ac035352d

PubMed ID: 15546002

Title: Severe combined immunodeficiency caused by deficiency in either the delta or the epsilon subunit of CD3.

PubMed ID: 15546002

DOI: 10.1172/jci22588

PubMed ID: 15294938

Title: Relevance of CD6-mediated interactions in T cell activation and proliferation.

PubMed ID: 15294938

DOI: 10.4049/jimmunol.173.4.2262

PubMed ID: 15972658

Title: The CD3epsilon proline-rich sequence, and its interaction with Nck, is not required for T cell development and function.

PubMed ID: 15972658

DOI: 10.4049/jimmunol.175.1.270

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 26507128

Title: CD3epsilon recruits Numb to promote TCR degradation.

PubMed ID: 26507128

DOI: 10.1093/intimm/dxv060

PubMed ID: 9698567

Title: Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathways revealed by the crystal structure of its regulatory SH2 domains bound to a dually phosphorylated ITAM peptide.

PubMed ID: 9698567

DOI: 10.1006/jmbi.1998.1964

PubMed ID: 15136729

Title: Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3.

PubMed ID: 15136729

DOI: 10.1073/pnas.0402295101

PubMed ID: 15534202

Title: Crystal structure of a human CD3-epsilon/delta dimer in complex with a UCHT1 single-chain antibody fragment.

PubMed ID: 15534202

DOI: 10.1073/pnas.0407359101

Sequence Information:

  • Length: 207
  • Mass: 23147
  • Checksum: A1603D01CE9957D7
  • Sequence:
    • MQSGTHWRVL GLCLLSVGVW GQDGNEEMGG ITQTPYKVSI SGTTVILTCP QYPGSEILWQ 
HNDKNIGGDE DDKNIGSDED HLSLKEFSEL EQSGYYVCYP RGSKPEDANF YLYLRARVCE 
NCMEMDVMSV ATIVIVDICI TGGLLLLVYY WSKNRKAKAK PVTRGAGAGG RQRGQNKERP 
PPVPNPDYEP IRKGQRDLYS GLNQRRI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.