Details for: HTR3B

Gene ID: 9177

Symbol: HTR3B

Ensembl ID: ENSG00000149305

Description: 5-hydroxytryptamine receptor 3B

Associated with

Other Information

Genular Protein ID: 2624779165

Symbol: 5HT3B_HUMAN

Name: Serotonin receptor 3B

UniProtKB Accession Codes:

O95264 B0YJ23 Q0VJC3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 2 CTD 1 ChEBI 3 ChEMBL 1 ComplexPortal 1 DNASU 1 DisGeNET 1 DrugBank 12 DrugCentral 1 EMBL 5 Ensembl 2 ExpressionAtlas 1 GO 10 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRINTS 3 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RNAct 1 Reactome 1 RefSeq 2 Rhea 3 SIGNOR 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TCDB 1 TopDownProteomics 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 10521471

Title: The pharmacological and functional characteristics of the serotonin 5-HT(3A) receptor are specifically modified by a 5-HT(3B) receptor subunit.

PubMed ID: 10521471

DOI: 10.1074/jbc.274.43.30799

PubMed ID: 9950429

Title: The 5-HT3B subunit is a major determinant of serotonin-receptor function.

PubMed ID: 9950429

DOI: 10.1038/16941

PubMed ID: 17010535

Title: Tissue-specific alternative promoters of the serotonin receptor gene HTR3B in human brain and intestine.

PubMed ID: 17010535

DOI: 10.1016/j.gene.2006.08.002

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12867984

Title: A cytoplasmic region determines single-channel conductance in 5-HT3 receptors.

PubMed ID: 12867984

DOI: 10.1038/nature01788

PubMed ID: 17392525

Title: Characterization of the novel human serotonin receptor subunits 5-HT3C, 5-HT3D, and 5-HT3E.

PubMed ID: 17392525

DOI: 10.1124/mol.106.032144

PubMed ID: 21138434

Title: The identification of N-glycosylated residues of the human 5-HT3B receptor subunit: importance for cell membrane expression.

PubMed ID: 21138434

DOI: 10.1111/j.1471-4159.2010.07129.x

PubMed ID: 15389765

Title: Investigation of the human serotonin receptor gene HTR3B in bipolar affective and schizophrenic patients.

PubMed ID: 15389765

DOI: 10.1002/ajmg.b.30070

PubMed ID: 15293096

Title: Mutational analysis of serotonin receptor genes: HTR3A and HTR3B in fibromyalgia patients.

PubMed ID: 15293096

DOI: 10.1007/s10067-004-0927-2

PubMed ID: 16487942

Title: Distinguishable haplotype blocks in the HTR3A and HTR3B region in the Japanese reveal evidence of association of HTR3B with female major depression.

PubMed ID: 16487942

DOI: 10.1016/j.biopsych.2005.11.008

PubMed ID: 21179162

Title: A population-specific HTR2B stop codon predisposes to severe impulsivity.

PubMed ID: 21179162

DOI: 10.1038/nature09629

Sequence Information:

  • Length: 441
  • Mass: 50292
  • Checksum: 2ED59E4E11400648
  • Sequence:
    • MLSSVMAPLW ACILVAAGIL ATDTHHPQDS ALYHLSKQLL QKYHKEVRPV YNWTKATTVY 
LDLFVHAILD VDAENQILKT SVWYQEVWND EFLSWNSSMF DEIREISLPL SAIWAPDIII 
NEFVDIERYP DLPYVYVNSS GTIENYKPIQ VVSACSLETY AFPFDVQNCS LTFKSILHTV 
EDVDLAFLRS PEDIQHDKKA FLNDSEWELL SVSSTYSILQ SSAGGFAQIQ FNVVMRRHPL 
VYVVSLLIPS IFLMLVDLGS FYLPPNCRAR IVFKTSVLVG YTVFRVNMSN QVPRSVGSTP 
LIGHFFTICM AFLVLSLAKS IVLVKFLHDE QRGGQEQPFL CLRGDTDADR PRVEPRAQRA 
VVTESSLYGE HLAQPGTLKE VWSQLQSISN YLQTQDQTDQ QEAEWLVLLS RFDRLLFQSY 
LFMLGIYTIT LCSLWALWGG V

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.