Details for: AP4M1

Gene ID: 9179

Symbol: AP4M1

Ensembl ID: ENSG00000221838

Description: adaptor related protein complex 4 subunit mu 1

Associated with

Other Information

Genular Protein ID: 4259449004

Symbol: AP4M1_HUMAN

Name: AP-4 adaptor complex mu subunit

UniProtKB Accession Codes:

O00189 D6W5U1 Q8WV65 Q9UHK9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DNASU 1 DisGeNET 1 EMBL 6 EPD 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 21 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 2 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 2 PIRSF 1 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TCDB 1 TopDownProteomics 1 TreeFam 1 UCSC 1 UniProtKB 3 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9013859

Title: Identification of two new mu-adaptin-related proteins, mu-ARP1 and mu-ARP2.

PubMed ID: 9013859

DOI: 10.1016/s0014-5793(96)01500-1

PubMed ID: 10436028

Title: Characterization of a fourth adaptor-related protein complex.

PubMed ID: 10436028

DOI: 10.1091/mbc.10.8.2787

PubMed ID: 11139587

Title: Signal-binding specificity of the mu4 subunit of the adaptor protein complex, AP-4.

PubMed ID: 11139587

DOI: 10.1074/jbc.m010591200

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10066790

Title: AP-4, a novel protein complex related to clathrin adaptors.

PubMed ID: 10066790

DOI: 10.1074/jbc.274.11.7278

PubMed ID: 19559397

Title: Mutation in the AP4M1 gene provides a model for neuroaxonal injury in cerebral palsy.

PubMed ID: 19559397

DOI: 10.1016/j.ajhg.2009.06.004

PubMed ID: 11802162

Title: AP-4 binds basolateral signals and participates in basolateral sorting in epithelial MDCK cells.

PubMed ID: 11802162

DOI: 10.1038/ncb745

PubMed ID: 26544806

Title: Association between rare variants in AP4E1, a component of intracellular trafficking, and persistent stuttering.

PubMed ID: 26544806

DOI: 10.1016/j.ajhg.2015.10.007

PubMed ID: 29180427

Title: AP-4 mediates export of ATG9A from the trans-Golgi network to promote autophagosome formation.

PubMed ID: 29180427

DOI: 10.1073/pnas.1717327114

PubMed ID: 32073997

Title: The FTS-Hook-FHIP (FHF) complex interacts with AP-4 to mediate perinuclear distribution of AP-4 and its cargo ATG9A.

PubMed ID: 32073997

DOI: 10.1091/mbc.e19-11-0658

PubMed ID: 20230749

Title: Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex.

PubMed ID: 20230749

DOI: 10.1016/j.devcel.2010.01.015

Sequence Information:

  • Length: 453
  • Mass: 49977
  • Checksum: AE3DCA8C5AED08B7
  • Sequence:
    • MISQFFILSS KGDPLIYKDF RGDSGGRDVA ELFYRKLTGL PGDESPVVMH HHGRHFIHIR 
HSGLYLVVTT SENVSPFSLL ELLSRLATLL GDYCGSLGEG TISRNVALVY ELLDEVLDYG 
YVQTTSTEML RNFIQTEAVV SKPFSLFDLS SVGLFGAETQ QSKVAPSSAA SRPVLSSRSD 
QSQKNEVFLD VVERLSVLIA SNGSLLKVDV QGEIRLKSFL PSGSEMRIGL TEEFCVGKSE 
LRGYGPGIRV DEVSFHSSVN LDEFESHRIL RLQPPQGELT VMRYQLSDDL PSPLPFRLFP 
SVQWDRGSGR LQVYLKLRCD LLSKSQALNV RLHLPLPRGV VSLSQELSSP EQKAELAEGA 
LRWDLPRVQG GSQLSGLFQM DVPGPPGPPS HGLSTSASPL GLGPASLSFE LPRHTCSGLQ 
VRFLRLAFRP CGNANPHKWV RHLSHSDAYV IRI

Genular Protein ID: 420608559

Symbol: C9JC87_HUMAN

Name: N/A

UniProtKB Accession Codes:

C9JC87

Database IDs:

ARBA 10 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 1 EPD 2 Ensembl 2 ExpressionAtlas 1 GO 5 Gene3D 2 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 6 MassIVE 1 MaxQB 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PRINTS 1 PROSITE 3 PeptideAtlas 1 Pfam 2 PhylomeDB 1 Proteomes 2 ProteomicsDB 1 RefSeq 2 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

Sequence Information:

  • Length: 460
  • Mass: 50691
  • Checksum: 86985C5110445050
  • Sequence:
    • MISQFFILSS KGDPLIYKDF RGDSGGRDVA ELFYRKLTGL PGDESPVVMV TSGGRRHHHG 
RHFIHIRHSG LYLVVTTSEN VSPFSLLELL SRLATLLGDY CGSLGEGTIS RNVALVYELL 
DEVLDYGYVQ TTSTEMLRNF IQTEAVVSKP FSLFDLSSVG LFGAETQQSK VAPSSAASRP 
VLSSRSDQSQ KNEVFLDVVE RLSVLIASNG SLLKVDVQGE IRLKSFLPSG SEMRIGLTEE 
FCVGKSELRG YGPGIRVDEV SFHSSVNLDE FESHRILRLQ PPQGELTVMR YQLSDDLPSP 
LPFRLFPSVQ WDRGSGRLQV YLKLRCDLLS KSQALNVRLH LPLPRGVVSL SQELSSPEQK 
AELAEGALRW DLPRVQGGSQ LSGLFQMDVP GPPGPPSHGL STSASPLGLG PASLSFELPR 
HTCSGLQVRF LRLAFRPCGN ANPHKWVRHL SHSDAYVIRI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.