OSMR | ENSG00000145623 | NCBI 9180

Details for: OSMR

Gene ID: 9180

Symbol: OSMR

Ensembl ID: ENSG00000145623

Description: oncostatin M receptor

Associated with

Cytokine signaling in immune system
(R-HSA-1280215)
Il-6-type cytokine receptor ligand interactions
(R-HSA-6788467)
Immune system
(R-HSA-168256)
Interleukin-6 family signaling
(R-HSA-6783589)
Signaling by interleukins
(R-HSA-449147)
Apical plasma membrane
(GO:0016324)
Ciliary neurotrophic factor receptor binding
(GO:0005127)
Cytokine-mediated signaling pathway
(GO:0019221)
Cytokine binding
(GO:0019955)
Cytokine receptor activity
(GO:0004896)
External side of plasma membrane
(GO:0009897)
Growth factor binding
(GO:0019838)
Oncostatin-m-mediated signaling pathway
(GO:0038165)
Oncostatin-m receptor activity
(GO:0004924)
Oncostatin-m receptor complex
(GO:0005900)
Plasma membrane
(GO:0005886)
Positive regulation of acute inflammatory response
(GO:0002675)
Positive regulation of cell population proliferation
(GO:0008284)
Protein binding
(GO:0005515)
Receptor complex
(GO:0043235)
Response to cytokine
(GO:0034097)

Other Information

Proteins

Oncostatin-M-specific receptor subunit beta

Genular Protein ID: 1772351135

Symbol: OSMR_HUMAN

Name: Oncostatin-M-specific receptor subunit beta

UniProtKB Accession Codes:

Q99650 Q6P4E8 Q96QJ6

Database IDs:

Citations:

PubMed ID: 8999038

Title: Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation.

PubMed ID: 8999038

DOI: 10.1074/jbc.271.51.32635

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15184896

Title: Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice.

PubMed ID: 15184896

DOI: 10.1038/ni1084

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21261663

Title: Functional effects of interleukin 31 in human primary keratinocytes.

PubMed ID: 21261663

DOI: 10.1111/j.1398-9995.2011.02545.x

PubMed ID: 18179886

Title: Oncostatin M receptor-beta mutations underlie familial primary localized cutaneous amyloidosis.

PubMed ID: 18179886

DOI: 10.1016/j.ajhg.2007.09.002

PubMed ID: 19690585

Title: Novel IL31RA gene mutation and ancestral OSMR mutant allele in familial primary cutaneous amyloidosis.

PubMed ID: 19690585

DOI: 10.1038/ejhg.2009.135

Sequence Information:

Length: 979
Mass: 110509
Checksum: 179852CA3D90D9EF
Sequence:

MALFAVFQTT FFLTLLSLRT YQSEVLAERL PLTPVSLKVS TNSTRQSLHL QWTVHNLPYH 
QELKMVFQIQ ISRIETSNVI WVGNYSTTVK WNQVLHWSWE SELPLECATH FVRIKSLVDD 
AKFPEPNFWS NWSSWEEVSV QDSTGQDILF VFPKDKLVEE GTNVTICYVS RNIQNNVSCY 
LEGKQIHGEQ LDPHVTAFNL NSVPFIRNKG TNIYCEASQG NVSEGMKGIV LFVSKVLEEP 
KDFSCETEDF KTLHCTWDPG TDTALGWSKQ PSQSYTLFES FSGEKKLCTH KNWCNWQITQ 
DSQETYNFTL IAENYLRKRS VNILFNLTHR VYLMNPFSVN FENVNATNAI MTWKVHSIRN 
NFTYLCQIEL HGEGKMMQYN VSIKVNGEYF LSELEPATEY MARVRCADAS HFWKWSEWSG 
QNFTTLEAAP SEAPDVWRIV SLEPGNHTVT LFWKPLSKLH ANGKILFYNV VVENLDKPSS 
SELHSIPAPA NSTKLILDRC SYQICVIANN SVGASPASVI VISADPENKE VEEERIAGTE 
GGFSLSWKPQ PGDVIGYVVD WCDHTQDVLG DFQWKNVGPN TTSTVISTDA FRPGVRYDFR 
IYGLSTKRIA CLLEKKTGYS QELAPSDNPH VLVDTLTSHS FTLSWKDYST ESQPGFIQGY 
HVYLKSKARQ CHPRFEKAVL SDGSECCKYK IDNPEEKALI VDNLKPESFY EFFITPFTSA 
GEGPSATFTK VTTPDEHSSM LIHILLPMVF CVLLIMVMCY LKSQWIKETC YPDIPDPYKS 
SILSLIKFKE NPHLIIMNVS DCIPDAIEVV SKPEGTKIQF LGTRKSLTET ELTKPNYLYL 
LPTEKNHSGP GPCICFENLT YNQAASDSGS CGHVPVSPKA PSMLGLMTSP ENVLKALEKN 
YMNSLGEIPA GETSLNYVSQ LASPMFGDKD SLPTNPVEAP HCSEYKMQMA VSLRLALPPP 
TENSSLSSIT LLDPGEHYC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: OSMR

Associated with

Other Information

Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation. PubMed ID: 8999038

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice. PubMed ID: 15184896

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

Functional effects of interleukin 31 in human primary keratinocytes. PubMed ID: 21261663

Oncostatin M receptor-beta mutations underlie familial primary localized cutaneous amyloidosis. PubMed ID: 18179886

Novel IL31RA gene mutation and ancestral OSMR mutant allele in familial primary cutaneous amyloidosis. PubMed ID: 19690585