Details for: REPS2

Gene ID: 9185

Symbol: REPS2

Ensembl ID: ENSG00000169891

Description: RALBP1 associated Eps domain containing 2

Associated with

Other Information

Genular Protein ID: 3698900538

Symbol: REPS2_HUMAN

Name: RalBP1-associated Eps domain-containing protein 2

UniProtKB Accession Codes:

Q8NFH8 A6PWZ6 O43428 Q5JNZ8 Q8NFI5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 4 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 5 EPD 1 Ensembl 2 EvolutionaryTrace 1 GO 8 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PRO 1 PROSITE 3 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 2 RefSeq 2 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9422736

Title: Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral.

PubMed ID: 9422736

DOI: 10.1074/jbc.273.2.814

PubMed ID: 12771942

Title: REPS2/POB1 is downregulated during human prostate cancer progression and inhibits growth factor signalling in prostate cancer cells.

PubMed ID: 12771942

DOI: 10.1038/sj.onc.1206397

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 10393179

Title: Small G protein Ral and its downstream molecules regulate endocytosis of EGF and insulin receptors.

PubMed ID: 10393179

DOI: 10.1093/emboj/18.13.3629

PubMed ID: 10557078

Title: Epsin binds to the EH domain of POB1 and regulates receptor-mediated endocytosis.

PubMed ID: 10557078

DOI: 10.1038/sj.onc.1202974

PubMed ID: 12149250

Title: Interaction of POB1, a downstream molecule of small G protein Ral, with PAG2, a paxillin-binding protein, is involved in cell migration.

PubMed ID: 12149250

DOI: 10.1074/jbc.m203453200

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 9928989

Title: Solution structure of the Eps15 homology domain of a human POB1 (partner of RalBP1).

PubMed ID: 9928989

DOI: 10.1016/s0014-5793(98)01644-5

PubMed ID: 23033978

Title: Diagnostic exome sequencing in persons with severe intellectual disability.

PubMed ID: 23033978

DOI: 10.1056/nejmoa1206524

Sequence Information:

  • Length: 660
  • Mass: 71534
  • Checksum: AACB3B8B8A9C2E3A
  • Sequence:
    • MEAAAAAAAA AAAAAAAGGG CGSGPPPLLL SEGEQQCYSE LFARCAGAAG GGPGSGPPEA 
ARVAPGTATA AAGPVADLFR ASQLPAETLH QITELCGAKR VGYFGPTQFY IALKLIAAAQ 
SGLPVRIESI KCELPLPRFM MSKNDGEIRF GNPAELHGTK VQIPYLTTEK NSFKRMDDED 
KQQETQSPTM SPLASPPSSP PHYQRVPLSH GYSKLRSSAE QMHPAPYEAR QPLVQPEGSS 
SGGPGTKPLR HQASLIRSFS VERELQDNSS YPDEPWRITE EQREYYVNQF RSLQPDPSSF 
ISGSVAKNFF TKSKLSIPEL SYIWELSDAD CDGALTLPEF CAAFHLIVAR KNGYPLPEGL 
PPTLQPEYLQ AAFPKPKWDC QLFDSYSESL PANQQPRDLN RMEKTSVKDM ADLPVPNQDV 
TSDDKQALKS TINEALPKDV SEDPATPKDS NSLKARPRSR SYSSTSIEEA MKRGEDPPTP 
PPRPQKTHSR ASSLDLNKVF QPSVPATKSG LLPPPPALPP RPCPSQSEQV SEAELLPQLS 
RAPSQAAESS PAKKDVLYSQ PPSKPIRRKF RPENQATENQ EPSTAASGPA SAATMKPHPT 
VQKQSSKQKK AIQTAIRKNK EANAVLARLN SELQQQLKEV HQERIALENQ LEQLRPVTVL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.