Details for: LGI1
Associated with
Other Information
Genular Protein ID: 1716769069
Symbol: LGI1_HUMAN
Name: Leucine-rich glioma-inactivated protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9879993
Title: A novel gene, LGI1, from 10q24 is rearranged and downregulated in malignant brain tumors.
PubMed ID: 9879993
PubMed ID: 11978770
Title: Mutations in the LGI1/Epitempin gene on 10q24 cause autosomal dominant lateral temporal epilepsy.
PubMed ID: 11978770
PubMed ID: 12975309
Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
PubMed ID: 12975309
DOI: 10.1101/gr.1293003
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15047712
Title: LGI1, a putative tumor metastasis suppressor gene, controls in vitro invasiveness and expression of matrix metalloproteinases in glioma cells through the ERK1/2 pathway.
PubMed ID: 15047712
PubMed ID: 17067999
Title: The epilepsy gene LGI1 encodes a secreted glycoprotein that binds to the cell surface.
PubMed ID: 17067999
DOI: 10.1093/hmg/ddl421
PubMed ID: 16518856
Title: Increased expression of LGI1 gene triggers growth inhibition and apoptosis of neuroblastoma cells.
PubMed ID: 16518856
DOI: 10.1002/jcp.20627
PubMed ID: 16787412
Title: The LGI1/epitempin gene encodes two protein isoforms differentially expressed in human brain.
PubMed ID: 16787412
PubMed ID: 17296837
Title: Two novel epilepsy-linked mutations leading to a loss of function of LGI1.
PubMed ID: 17296837
PubMed ID: 27066583
Title: Dysfunctional ADAM22 implicated in progressive encephalopathy with cortical atrophy and epilepsy.
PubMed ID: 27066583
PubMed ID: 19191227
Title: LGI1 mutations in autosomal dominant and sporadic lateral temporal epilepsy.
PubMed ID: 19191227
DOI: 10.1002/humu.20925
PubMed ID: 11810107
Title: Mutations in LGI1 cause autosomal-dominant partial epilepsy with auditory features.
PubMed ID: 11810107
DOI: 10.1038/ng832
PubMed ID: 12205652
Title: LGI1 is mutated in familial temporal lobe epilepsy characterized by aphasic seizures.
PubMed ID: 12205652
DOI: 10.1002/ana.10280
PubMed ID: 12601709
Title: Epilepsy with auditory features: a LGI1 gene mutation suggests a loss-of-function mechanism.
PubMed ID: 12601709
DOI: 10.1002/ana.10492
PubMed ID: 12771268
Title: Novel LGI1 mutation in a family with autosomal dominant partial epilepsy with auditory features.
PubMed ID: 12771268
PubMed ID: 15079010
Title: LGI1 mutations in temporal lobe epilepsies.
PubMed ID: 15079010
PubMed ID: 17562837
Title: A de novo LGI1 mutation causing idiopathic partial epilepsy with telephone-induced seizures.
PubMed ID: 17562837
PubMed ID: 18625862
Title: A novel loss-of-function LGI1 mutation linked to autosomal dominant lateral temporal epilepsy.
PubMed ID: 18625862
PubMed ID: 19552651
Title: Drug resistant ADLTE and recurrent partial status epilepticus with dysphasic features in a family with a novel LGI1mutation: electroclinical, genetic, and EEG/fMRI findings.
PubMed ID: 19552651
Sequence Information:
- Length: 557
- Mass: 63818
- Checksum: 890EEDA08D95C854
- Sequence:
MESERSKRMG NACIPLKRIA YFLCLLSALL LTEGKKPAKP KCPAVCTCTK DNALCENARS IPRTVPPDVI SLSFVRSGFT EISEGSFLFT PSLQLLLFTS NSFDVISDDA FIGLPHLEYL FIENNNIKSI SRHTFRGLKS LIHLSLANNN LQTLPKDIFK GLDSLTNVDL RGNSFNCDCK LKWLVEWLGH TNATVEDIYC EGPPEYKKRK INSLSSKDFD CIITEFAKSQ DLPYQSLSID TFSYLNDEYV VIAQPFTGKC IFLEWDHVEK TFRNYDNITG TSTVVCKPIV IETQLYVIVA QLFGGSHIYK RDSFANKFIK IQDIEILKIR KPNDIETFKI ENNWYFVVAD SSKAGFTTIY KWNGNGFYSH QSLHAWYRDT DVEYLEIVRT PQTLRTPHLI LSSSSQRPVI YQWNKATQLF TNQTDIPNME DVYAVKHFSV KGDVYICLTR FIGDSKVMKW GGSSFQDIQR MPSRGSMVFQ PLQINNYQYA ILGSDYSFTQ VYNWDAEKAK FVKFQELNVQ APRSFTHVSI NKRNFLFASS FKGNTQIYKH VIVDLSA
Genular Protein ID: 2342218478
Symbol: A0A0S2Z5G1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 26871637
Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
PubMed ID: 26871637
Sequence Information:
- Length: 243
- Mass: 27605
- Checksum: 65761BE3D9E7E625
- Sequence:
MESERSKRMG NACIPLKRIA YFLCLLSALL LTEGKKPAKP KCPAVCTCTK DNALCENARS IPRTVPPDVI SLSFVRSGFT EISEGSFLFT PSLQLLSLAN NNLQTLPKDI FKGLDSLTNV DLRGNSFNCD CKLKWLVEWL GHTNATVEDI YCEGPPEYKK RKINSLSSKD FDCIITEFAK SQDLPYQSLS IDTFSYLNDE YVVIAQPFTG KCIFLEWDHV EKTFRNYDNI TVLREIHRFT NMS
Genular Protein ID: 60262944
Symbol: A0A0S2Z4X3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181995
PubMed ID: 26871637
Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
PubMed ID: 26871637
Sequence Information:
- Length: 291
- Mass: 33121
- Checksum: BC10E3E110E016D0
- Sequence:
MESERSKRMG NACIPLKRIA YFLCLLSALL LTEGKKPAKP KCPAVCTCTK DNALCENARS IPRTVPPDVI SLSFVRSGFT EISEGSFLFT PSLQLLLFTS NSFDVISDDA FIGLPHLEYL FIENNNIKSI SRHTFRGLKS LIHLSLANNN LQTLPKDIFK GLDSLTNVDL RGNSFNCDCK LKWLVEWLGH TNATVEDIYC EGPPEYKKRK INSLSSKDFD CIITEFAKSQ DLPYQSLSID TFSYLNDEYV VIAQPFTGKC IFLEWDHVEK TFRNYDNITV LREIHRFTNM S
Genular Protein ID: 3531951123
Symbol: A0A1B0GUD3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
Sequence Information:
- Length: 281
- Mass: 31780
- Checksum: 96DF2D954C55C3CF
- Sequence:
MESERSKRMG NACIPLKRIA YFLCLLSALL LTEGKKPAKP KCPAVCTCTK DNALCENARS IPRTVPPDVI SLSFVRSGFT EISEGSFLFT PSLQLLLFTS NSFDVISDDA FIGLPHLEYL FIENNNIKSI SRHTFRGLKS LIHLSLANNN LQTLPKDIFK GLDSLTNVDL RGNSFNCDCK LKWLVEWLGH TNATVEDIYC EGPPEYKKRK INSLSSKDFD CIITEFAKSQ DLPYQSLSID TFSYLNDEYV VIAQPFTGKC IFLEWDHVEK TFRNYDNITG S
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.