Details for: VAPA

Gene ID: 9218

Symbol: VAPA

Ensembl ID: ENSG00000101558

Description: VAMP associated protein A

Associated with

Other Information

Genular Protein ID: 3739504681

Symbol: VAPA_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10523508

Title: VAP-33 localizes to both an intracellular vesicle population and with occludin at the tight junction.

PubMed ID: 10523508

DOI: 10.1242/jcs.112.21.3723

PubMed ID: 16177791

Title: DNA sequence and analysis of human chromosome 18.

PubMed ID: 16177791

DOI: 10.1038/nature03983

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9657962

Title: Identification of a human homologue of the vesicle-associated membrane protein (VAMP)-associated protein of 33 kDa (VAP-33): a broadly expressed protein that binds to VAMP.

PubMed ID: 9657962

DOI: 10.1042/bj3330247

PubMed ID: 9920726

Title: Molecular cloning and characterization of mammalian homologues of vesicle-associated membrane protein-associated (VAMP-associated) proteins.

PubMed ID: 9920726

DOI: 10.1006/bbrc.1998.9876

PubMed ID: 11511104

Title: VAP-A binds promiscuously to both v- and tSNAREs.

PubMed ID: 11511104

DOI: 10.1006/bbrc.2001.5437

PubMed ID: 16143324

Title: Targeting of OSBP-related protein 3 (ORP3) to endoplasmic reticulum and plasma membrane is controlled by multiple determinants.

PubMed ID: 16143324

DOI: 10.1016/j.yexcr.2005.08.003

PubMed ID: 16895911

Title: Efficient trafficking of ceramide from the endoplasmic reticulum to the Golgi apparatus requires a VAMP-associated protein-interacting FFAT motif of CERT.

PubMed ID: 16895911

DOI: 10.1074/jbc.m605032200

PubMed ID: 19289470

Title: Promotion of neurite extension by protrudin requires its interaction with vesicle-associated membrane protein-associated protein.

PubMed ID: 19289470

DOI: 10.1074/jbc.m807938200

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21976701

Title: Protrudin serves as an adaptor molecule that connects KIF5 and its cargoes in vesicular transport during process formation.

PubMed ID: 21976701

DOI: 10.1091/mbc.e11-01-0068

PubMed ID: 21957124

Title: Viperin inhibits hepatitis C virus replication by interfering with binding of NS5A to host protein hVAP-33.

PubMed ID: 21957124

DOI: 10.1099/vir.0.033860-0

PubMed ID: 23601107

Title: The antiviral effector IFITM3 disrupts intracellular cholesterol homeostasis to block viral entry.

PubMed ID: 23601107

DOI: 10.1016/j.chom.2013.03.006

PubMed ID: 24105263

Title: STARD3 or STARD3NL and VAP form a novel molecular tether between late endosomes and the ER.

PubMed ID: 24105263

DOI: 10.1242/jcs.139295

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25447204

Title: OSBP-related protein 3 (ORP3) coupling with VAMP-associated protein A regulates R-Ras activity.

PubMed ID: 25447204

DOI: 10.1016/j.yexcr.2014.10.019

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 29858488

Title: Identification of MOSPD2, a novel scaffold for endoplasmic reticulum membrane contact sites.

PubMed ID: 29858488

DOI: 10.15252/embr.201745453

PubMed ID: 30741634

Title: Human VPS13A is associated with multiple organelles and influences mitochondrial morphology and lipid droplet motility.

PubMed ID: 30741634

DOI: 10.7554/elife.43561

PubMed ID: 30659099

Title: The activity of Sac1 across ER-TGN contact sites requires the four-phosphate-adaptor-protein-1.

PubMed ID: 30659099

DOI: 10.1083/jcb.201812021

PubMed ID: 32344433

Title: GRAF2, WDR44, and MICAL1 mediate Rab8/10/11-dependent export of E-cadherin, MMP14, and CFTR DeltaF508.

PubMed ID: 32344433

DOI: 10.1083/jcb.201811014

PubMed ID: 20178991

Title: Electrostatic interaction between oxysterol-binding protein and VAMP-associated protein A revealed by NMR and mutagenesis studies.

PubMed ID: 20178991

DOI: 10.1074/jbc.m109.082602

PubMed ID: 33124732

Title: FFAT motif phosphorylation controls formation and lipid transfer function of inter-organelle contacts.

PubMed ID: 33124732

DOI: 10.15252/embj.2019104369

Sequence Information:

  • Length: 249
  • Mass: 27893
  • Checksum: 68B603F3A9FA5475
  • Sequence:
  • MASASGAMAK HEQILVLDPP TDLKFKGPFT DVVTTNLKLR NPSDRKVCFK VKTTAPRRYC 
    VRPNSGIIDP GSTVTVSVML QPFDYDPNEK SKHKFMVQTI FAPPNTSDME AVWKEAKPDE 
    LMDSKLRCVF EMPNENDKLN DMEPSKAVPL NASKQDGPMP KPHSVSLNDT ETRKLMEECK 
    RLQGEMMKLS EENRHLRDEG LRLRKVAHSD KPGSTSTASF RDNVTSPLPS LLVVIAAIFI 
    GFFLGKFIL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.