Details for: CD6

Gene ID: 923

Symbol: CD6

Ensembl ID: ENSG00000013725

Description: CD6 molecule

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 41.0813
    Cell Significance Index: -6.3900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 26.6122
    Cell Significance Index: -6.7500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 10.8092
    Cell Significance Index: -10.3200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 5.1827
    Cell Significance Index: -6.3900
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 3.1105
    Cell Significance Index: 9.4800
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 2.5479
    Cell Significance Index: 74.8300
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 2.5292
    Cell Significance Index: 25.3600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 1.8688
    Cell Significance Index: -5.7400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 1.7334
    Cell Significance Index: -6.8400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1.4022
    Cell Significance Index: 44.9100
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 1.0117
    Cell Significance Index: 10.4900
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: 0.4939
    Cell Significance Index: 4.3200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.4274
    Cell Significance Index: 81.3400
  • Cell Name: hepatic pit cell (CL2000054)
    Fold Change: 0.3173
    Cell Significance Index: 0.8500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.2820
    Cell Significance Index: 6.0100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 0.2613
    Cell Significance Index: -0.7000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2561
    Cell Significance Index: 25.3300
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 0.1889
    Cell Significance Index: 1.0300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1755
    Cell Significance Index: 10.5400
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 0.1709
    Cell Significance Index: 1.2300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1645
    Cell Significance Index: 148.5000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1549
    Cell Significance Index: 16.8500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1351
    Cell Significance Index: 21.9800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.1306
    Cell Significance Index: 1.8700
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: 0.0916
    Cell Significance Index: 0.7800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0594
    Cell Significance Index: 4.1100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0503
    Cell Significance Index: 10.1000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0139
    Cell Significance Index: 4.9800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0073
    Cell Significance Index: 0.2100
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: 0.0064
    Cell Significance Index: 0.0600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.0041
    Cell Significance Index: 0.2500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0008
    Cell Significance Index: 1.5300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0004
    Cell Significance Index: -0.0200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0023
    Cell Significance Index: -0.0800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0032
    Cell Significance Index: -5.8700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0035
    Cell Significance Index: -5.3400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0037
    Cell Significance Index: -5.0100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0058
    Cell Significance Index: -1.6800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0060
    Cell Significance Index: -0.1500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0074
    Cell Significance Index: -3.2700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0087
    Cell Significance Index: -6.6000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0092
    Cell Significance Index: -0.2000
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: -0.0094
    Cell Significance Index: -0.0900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0105
    Cell Significance Index: -7.7500
  • Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
    Fold Change: -0.0109
    Cell Significance Index: -0.0900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0110
    Cell Significance Index: -6.0000
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0122
    Cell Significance Index: -0.2100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0129
    Cell Significance Index: -7.2700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0149
    Cell Significance Index: -10.8900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0152
    Cell Significance Index: -9.6600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0152
    Cell Significance Index: -3.0200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0154
    Cell Significance Index: -1.9800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0163
    Cell Significance Index: -1.9200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0186
    Cell Significance Index: -8.4600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0322
    Cell Significance Index: -5.4900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0364
    Cell Significance Index: -7.6700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0394
    Cell Significance Index: -7.1100
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0418
    Cell Significance Index: -0.6300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0458
    Cell Significance Index: -6.2900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0554
    Cell Significance Index: -6.8100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0569
    Cell Significance Index: -8.2800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0574
    Cell Significance Index: -6.6900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0588
    Cell Significance Index: -1.2200
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: -0.0616
    Cell Significance Index: -0.5200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0626
    Cell Significance Index: -6.5200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0664
    Cell Significance Index: -8.5800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0664
    Cell Significance Index: -7.6100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0693
    Cell Significance Index: -7.0800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0711
    Cell Significance Index: -3.3400
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0755
    Cell Significance Index: -1.9300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0811
    Cell Significance Index: -3.7800
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -0.0816
    Cell Significance Index: -1.1100
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0853
    Cell Significance Index: -3.7100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0867
    Cell Significance Index: -5.8300
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.0872
    Cell Significance Index: -1.0300
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: -0.0919
    Cell Significance Index: -0.8300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0930
    Cell Significance Index: -7.1400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0959
    Cell Significance Index: -6.0500
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.0960
    Cell Significance Index: -0.9100
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0971
    Cell Significance Index: -1.6500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1003
    Cell Significance Index: -4.4400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1010
    Cell Significance Index: -5.3000
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.1108
    Cell Significance Index: -1.6200
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: -0.1109
    Cell Significance Index: -1.1200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1167
    Cell Significance Index: -4.4200
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1216
    Cell Significance Index: -4.2600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1221
    Cell Significance Index: -9.1000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1236
    Cell Significance Index: -7.6000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1312
    Cell Significance Index: -3.5100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1329
    Cell Significance Index: -7.4600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1379
    Cell Significance Index: -10.9200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1419
    Cell Significance Index: -7.3700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1428
    Cell Significance Index: -9.2100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1470
    Cell Significance Index: -7.4300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1506
    Cell Significance Index: -4.2100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1597
    Cell Significance Index: -5.2300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1623
    Cell Significance Index: -5.1700
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.1690
    Cell Significance Index: -6.9200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1769
    Cell Significance Index: -4.7400
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: -0.1785
    Cell Significance Index: -1.7400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Transmembrane Glycoprotein:** CD6 is a transmembrane glycoprotein consisting of an extracellular domain, a transmembrane domain, and an intracellular domain. 2. **Co-receptor for TCR:** CD6 acts as a co-receptor for the TCR, enhancing the affinity of T cells for antigens presented by MHC molecules. 3. **Expression in Mature T Cells:** CD6 is predominantly expressed in mature T cells, including alpha-beta T cells, gamma-delta T cells, and T-helper 22 cells. 4. **Regulation of T Cell Proliferation:** CD6 plays a crucial role in regulating T cell proliferation, particularly in the context of antigen-specific responses. **Pathways and Functions:** 1. **Acute Inflammatory Response:** CD6 is involved in the regulation of the acute inflammatory response, particularly in the context of lipopolysaccharide (LPS) stimulation. 2. **Adaptive Immune Response:** CD6 facilitates the adaptive immune response by enhancing the recognition of antigens presented by MHC molecules. 3. **Immunological Synapse:** CD6 is essential for the formation of the immunological synapse, a critical structure for T cell-antigen presentation. 4. **Innate Immunity:** CD6 is also involved in innate immunity, particularly in the context of LPS-mediated signaling pathways. **Clinical Significance:** 1. **Immunodeficiency Disorders:** Mutations or alterations in the CD6 gene have been associated with immunodeficiency disorders, highlighting its importance in the regulation of the immune system. 2. **Autoimmune Diseases:** CD6 dysfunction has been implicated in the pathogenesis of autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis. 3. **Cancer Immunotherapy:** CD6 has been recognized as a potential target for cancer immunotherapy, given its role in regulating T cell responses. In conclusion, the CD6 gene plays a critical role in the functioning of T cells and the regulation of the immune system. Its involvement in various immune responses and its potential as a therapeutic target make it an important area of research in immunology.

Genular Protein ID: 2759517839

Symbol: CD6_HUMAN

Name: T12

UniProtKB Accession Codes:

P30203 A4KAD4 A4KAD5 Q8WWJ3 Q8WWJ4 Q8WWJ5 Q8WWJ6 Q8WWJ7 Q9UMF2 Q9Y4K7 Q9Y4K8 Q9Y4K9 Q9Y4L0

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CPTAC 3 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 16 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 18 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 RNAct 1 RefSeq 5 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9013954

Title: Structure and chromosomal location of the human CD6 gene: detection of five human CD6 isoforms.

PubMed ID: 9013954

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 1919444

Title: The lymphocyte glycoprotein CD6 contains a repeated domain structure characteristic of a new family of cell surface and secreted proteins.

PubMed ID: 1919444

DOI: 10.1084/jem.174.4.949

PubMed ID: 17371992

Title: Extracellular isoforms of CD6 generated by alternative splicing regulate targeting of CD6 to the immunological synapse.

PubMed ID: 17371992

DOI: 10.4049/jimmunol.178.7.4351

PubMed ID: 2016320

Title: Biosynthesis and post-translational modification of CD6, a T cell signal-transducing molecule.

PubMed ID: 2016320

DOI: 10.1016/s0021-9258(20)89621-5

PubMed ID: 7678115

Title: Tyrosine phosphorylation of CD6 by stimulation of CD3: augmentation by the CD4 and CD2 coreceptors.

PubMed ID: 7678115

DOI: 10.1084/jem.177.1.219

PubMed ID: 15048703

Title: Frontline: Optimal T cell activation requires the engagement of CD6 and CD166.

PubMed ID: 15048703

DOI: 10.1002/eji.200424856

PubMed ID: 15294938

Title: Relevance of CD6-mediated interactions in T cell activation and proliferation.

PubMed ID: 15294938

DOI: 10.4049/jimmunol.173.4.2262

PubMed ID: 16352806

Title: Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation induced by dendritic cells.

PubMed ID: 16352806

DOI: 10.1182/blood-2005-09-3881

PubMed ID: 16914752

Title: CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76.

PubMed ID: 16914752

DOI: 10.1128/mcb.00688-06

PubMed ID: 17601777

Title: CD6 binds to pathogen-associated molecular patterns and protects from LPS-induced septic shock.

PubMed ID: 17601777

DOI: 10.1073/pnas.0702815104

PubMed ID: 24945728

Title: Modulation of CD6 function through interaction with galectin-1 and -3.

PubMed ID: 24945728

DOI: 10.1016/j.febslet.2014.05.064

PubMed ID: 24584089

Title: Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub.

PubMed ID: 24584089

DOI: 10.1038/ni.2843

PubMed ID: 26146185

Title: Structures of CD6 and its ligand CD166 give insight into their interaction.

PubMed ID: 26146185

DOI: 10.1016/j.str.2015.05.019

Sequence Information:

  • Length: 668
  • Mass: 71801
  • Checksum: 59E6790E77FFBC42
  • Sequence:
    • MWLFFGITGL LTAALSGHPS PAPPDQLNTS SAESELWEPG ERLPVRLTNG SSSCSGTVEV 
RLEASWEPAC GALWDSRAAE AVCRALGCGG AEAASQLAPP TPELPPPPAA GNTSVAANAT 
LAGAPALLCS GAEWRLCEVV EHACRSDGRR ARVTCAENRA LRLVDGGGAC AGRVEMLEHG 
EWGSVCDDTW DLEDAHVVCR QLGCGWAVQA LPGLHFTPGR GPIHRDQVNC SGAEAYLWDC 
PGLPGQHYCG HKEDAGAVCS EHQSWRLTGG ADRCEGQVEV HFRGVWNTVC DSEWYPSEAK 
VLCQSLGCGT AVERPKGLPH SLSGRMYYSC NGEELTLSNC SWRFNNSNLC SQSLAARVLC 
SASRSLHNLS TPEVPASVQT VTIESSVTVK IENKESRELM LLIPSIVLGI LLLGSLIFIA 
FILLRIKGKY ALPVMVNHQH LPTTIPAGSN SYQPVPITIP KEVFMLPIQV QAPPPEDSDS 
GSDSDYEHYD FSAQPPVALT TFYNSQRHRV TDEEVQQSRF QMPPLEEGLE ELHASHIPTA 
NPGHCITDPP SLGPQYHPRS NSESSTSSGE DYCNSPKSKL PPWNPQVFSS ERSSFLEQPP 
NLELAGTQPA FSAGPPADDS SSTSSGEWYQ NFQPPPQPPS EEQFGCPGSP SPQPDSTDND 
DYDDISAA

Genular Protein ID: 1190149398

Symbol: Q6AZ88_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6AZ88

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 SAM 3 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 668
  • Mass: 71889
  • Checksum: 4D2C01A6FFEDF1D2
  • Sequence:
    • MWLFFGITGL LTAALSGHPS PAPPDQLNTS SAESELWEPG ERLPVRLTNG SSSCSGTVEV 
RLEASWEPAC GALWDSRAAE AVCRALGCGG AEAASQLAPP TPELPPPPAA GNTSVAANAT 
LAGAPALLCS GAEWRLCEVV EHACRSDGRR ARVTCAENRA LRLVDGGGAC AGRVEMLEHG 
EWGSVCDDTW DLEDAHVVCR QLGCGWAVQA LPGLHFMPGR GPIHRDQVNC SGAEAYLWDC 
PGLPGQHYCG HKEDAGVVCS EHQSWRLTGG ADRCEGQVEV HFRGVWNTVC DSEWYPSEAK 
VLCQSLGCGT AVERPKGLPH SLSGRMYYSC NGEELTLSNC SWRFNNSNLC SQSLAARVLC 
SASRSLHNLS TPEVPASVQT VTIESSVTVK IENKESRELM LLIPSIVLGI LLLGSLIFIA 
FILLRIKGKY ALPVMVNHQH LPTTIPAGSN SYQPVPITIP KEVFMLPIQV QAPPPEDSDS 
GSDSDYEHYD FSAQPPVALT TFYNSQRHRV TDEEVQQSRF QMPPLEEGLE ELHASHIPTA 
NPGHCITDPP SLGPQYHPRS NSESSTSSGE DYCNSPKSKL PPWNPQVFSS ERSSFLEQPP 
NLELASTQPA FSAGPPADDS SSTSSGEWYQ NFQPPPQPPS EEQFGCPGSP SPQPDSTDND 
DYDDISAA

Genular Protein ID: 2996535022

Symbol: Q8N4Q7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8N4Q7

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 SAM 3 SMART 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 639
  • Mass: 68925
  • Checksum: 40A104F4618FE10F
  • Sequence:
    • MWLFFGITGL LTAALSGHPS PAPPDQLNTS SAESELWEPG ERLPVRLTNG SSSCSGTVEV 
RLEASWEPAC GALWDSRAAE AVCRALGCGG AEAASQLAPP TPELPPPPAA GNTSVAANAT 
LAGAPALLCS GAEWRLCEVV EHACRSDGRR ARVTCAENRA LRLVDGGGAC AGRVEMLEHG 
EWGSVCDDTW DLEDAHVVCR QLGCGWAVQA LPGLHFTPGR GPIHRDQVNC SGAEAYLWDC 
PGLPGQHYCG HKEDAGAVCS EHQSWRLTGG ADRCEGQVEV HFRGVWNTVC DSEWYPSEAK 
VLCQSLGCGT AVERPKGLPH SLSGRMYYSC NGEELTLSNC SWRFNNSNLC SQSLAARVLC 
SASRSLHNLS TPEVPASVQT VTIESSVTVK IENKESRELM LLIPSIVLGI LLLGSLIFIA 
FILLRIKGKY ALPVMVNHQH LPTTIPAGSN SYQPVPITIP KEVFMLPIQV QAPPPEDSDS 
GSDSDYEHYD FSAQPPVALT TFYNSQRHRV TDEEVQQSRF QMPPLEEGLE ELHASHIPTA 
NPGHCITDPP SLGPQYHPRS NSESSTSSGE DYCNSPKSKL PPWNPQVFSS ERSSFLEQPP 
NLELAGTQPA FSGPPADDSS STSSGEWYQN FQPRLLGWL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.