Associated with
Other Information
Genular Protein ID: 2759517839
Symbol: CD6_HUMAN
Name: T12
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9013954
Title: Structure and chromosomal location of the human CD6 gene: detection of five human CD6 isoforms.
PubMed ID: 9013954
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 1919444
Title: The lymphocyte glycoprotein CD6 contains a repeated domain structure characteristic of a new family of cell surface and secreted proteins.
PubMed ID: 1919444
PubMed ID: 17371992
Title: Extracellular isoforms of CD6 generated by alternative splicing regulate targeting of CD6 to the immunological synapse.
PubMed ID: 17371992
PubMed ID: 2016320
Title: Biosynthesis and post-translational modification of CD6, a T cell signal-transducing molecule.
PubMed ID: 2016320
PubMed ID: 7678115
Title: Tyrosine phosphorylation of CD6 by stimulation of CD3: augmentation by the CD4 and CD2 coreceptors.
PubMed ID: 7678115
PubMed ID: 15048703
Title: Frontline: Optimal T cell activation requires the engagement of CD6 and CD166.
PubMed ID: 15048703
PubMed ID: 15294938
Title: Relevance of CD6-mediated interactions in T cell activation and proliferation.
PubMed ID: 15294938
PubMed ID: 16352806
Title: Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation induced by dendritic cells.
PubMed ID: 16352806
PubMed ID: 16914752
Title: CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76.
PubMed ID: 16914752
DOI: 10.1128/mcb.00688-06
PubMed ID: 17601777
Title: CD6 binds to pathogen-associated molecular patterns and protects from LPS-induced septic shock.
PubMed ID: 17601777
PubMed ID: 24945728
Title: Modulation of CD6 function through interaction with galectin-1 and -3.
PubMed ID: 24945728
PubMed ID: 24584089
Title: Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub.
PubMed ID: 24584089
DOI: 10.1038/ni.2843
PubMed ID: 26146185
Title: Structures of CD6 and its ligand CD166 give insight into their interaction.
PubMed ID: 26146185
Sequence Information:
- Length: 668
- Mass: 71801
- Checksum: 59E6790E77FFBC42
- Sequence:
MWLFFGITGL LTAALSGHPS PAPPDQLNTS SAESELWEPG ERLPVRLTNG SSSCSGTVEV RLEASWEPAC GALWDSRAAE AVCRALGCGG AEAASQLAPP TPELPPPPAA GNTSVAANAT LAGAPALLCS GAEWRLCEVV EHACRSDGRR ARVTCAENRA LRLVDGGGAC AGRVEMLEHG EWGSVCDDTW DLEDAHVVCR QLGCGWAVQA LPGLHFTPGR GPIHRDQVNC SGAEAYLWDC PGLPGQHYCG HKEDAGAVCS EHQSWRLTGG ADRCEGQVEV HFRGVWNTVC DSEWYPSEAK VLCQSLGCGT AVERPKGLPH SLSGRMYYSC NGEELTLSNC SWRFNNSNLC SQSLAARVLC SASRSLHNLS TPEVPASVQT VTIESSVTVK IENKESRELM LLIPSIVLGI LLLGSLIFIA FILLRIKGKY ALPVMVNHQH LPTTIPAGSN SYQPVPITIP KEVFMLPIQV QAPPPEDSDS GSDSDYEHYD FSAQPPVALT TFYNSQRHRV TDEEVQQSRF QMPPLEEGLE ELHASHIPTA NPGHCITDPP SLGPQYHPRS NSESSTSSGE DYCNSPKSKL PPWNPQVFSS ERSSFLEQPP NLELAGTQPA FSAGPPADDS SSTSSGEWYQ NFQPPPQPPS EEQFGCPGSP SPQPDSTDND DYDDISAA
Genular Protein ID: 2996535022
Symbol: Q8N4Q7_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 639
- Mass: 68925
- Checksum: 40A104F4618FE10F
- Sequence:
MWLFFGITGL LTAALSGHPS PAPPDQLNTS SAESELWEPG ERLPVRLTNG SSSCSGTVEV RLEASWEPAC GALWDSRAAE AVCRALGCGG AEAASQLAPP TPELPPPPAA GNTSVAANAT LAGAPALLCS GAEWRLCEVV EHACRSDGRR ARVTCAENRA LRLVDGGGAC AGRVEMLEHG EWGSVCDDTW DLEDAHVVCR QLGCGWAVQA LPGLHFTPGR GPIHRDQVNC SGAEAYLWDC PGLPGQHYCG HKEDAGAVCS EHQSWRLTGG ADRCEGQVEV HFRGVWNTVC DSEWYPSEAK VLCQSLGCGT AVERPKGLPH SLSGRMYYSC NGEELTLSNC SWRFNNSNLC SQSLAARVLC SASRSLHNLS TPEVPASVQT VTIESSVTVK IENKESRELM LLIPSIVLGI LLLGSLIFIA FILLRIKGKY ALPVMVNHQH LPTTIPAGSN SYQPVPITIP KEVFMLPIQV QAPPPEDSDS GSDSDYEHYD FSAQPPVALT TFYNSQRHRV TDEEVQQSRF QMPPLEEGLE ELHASHIPTA NPGHCITDPP SLGPQYHPRS NSESSTSSGE DYCNSPKSKL PPWNPQVFSS ERSSFLEQPP NLELAGTQPA FSGPPADDSS STSSGEWYQN FQPRLLGWL
Genular Protein ID: 1190149398
Symbol: Q6AZ88_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 668
- Mass: 71889
- Checksum: 4D2C01A6FFEDF1D2
- Sequence:
MWLFFGITGL LTAALSGHPS PAPPDQLNTS SAESELWEPG ERLPVRLTNG SSSCSGTVEV RLEASWEPAC GALWDSRAAE AVCRALGCGG AEAASQLAPP TPELPPPPAA GNTSVAANAT LAGAPALLCS GAEWRLCEVV EHACRSDGRR ARVTCAENRA LRLVDGGGAC AGRVEMLEHG EWGSVCDDTW DLEDAHVVCR QLGCGWAVQA LPGLHFMPGR GPIHRDQVNC SGAEAYLWDC PGLPGQHYCG HKEDAGVVCS EHQSWRLTGG ADRCEGQVEV HFRGVWNTVC DSEWYPSEAK VLCQSLGCGT AVERPKGLPH SLSGRMYYSC NGEELTLSNC SWRFNNSNLC SQSLAARVLC SASRSLHNLS TPEVPASVQT VTIESSVTVK IENKESRELM LLIPSIVLGI LLLGSLIFIA FILLRIKGKY ALPVMVNHQH LPTTIPAGSN SYQPVPITIP KEVFMLPIQV QAPPPEDSDS GSDSDYEHYD FSAQPPVALT TFYNSQRHRV TDEEVQQSRF QMPPLEEGLE ELHASHIPTA NPGHCITDPP SLGPQYHPRS NSESSTSSGE DYCNSPKSKL PPWNPQVFSS ERSSFLEQPP NLELASTQPA FSAGPPADDS SSTSSGEWYQ NFQPPPQPPS EEQFGCPGSP SPQPDSTDND DYDDISAA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.