RAB11B | ENSG00000185236 | NCBI 9230

Details for: RAB11B

Gene ID: 9230

Symbol: RAB11B

Ensembl ID: ENSG00000185236

Description: RAB11B, member RAS oncogene family

Associated with

Membrane trafficking
(R-HSA-199991)
Metabolism of proteins
(R-HSA-392499)
Post-translational protein modification
(R-HSA-597592)
Rab geranylgeranylation
(R-HSA-8873719)
Rab regulation of trafficking
(R-HSA-9007101)
Tbc/rabgaps
(R-HSA-8854214)
Vesicle-mediated transport
(R-HSA-5653656)
Amyloid-beta clearance by transcytosis
(GO:0150093)
Cadherin binding
(GO:0045296)
Cellular response to acidic ph
(GO:0071468)
Constitutive secretory pathway
(GO:0045054)
Cytosol
(GO:0005829)
Endocytic recycling
(GO:0032456)
Establishment of protein localization to membrane
(GO:0090150)
Extracellular exosome
(GO:0070062)
Gdp binding
(GO:0019003)
Golgi apparatus
(GO:0005794)
G protein activity
(GO:0003925)
Gtpase activity
(GO:0003924)
Gtp binding
(GO:0005525)
Insulin secretion involved in cellular response to glucose stimulus
(GO:0035773)
Melanosome transport
(GO:0032402)
Myosin v binding
(GO:0031489)
Phagocytic vesicle
(GO:0045335)
Phagocytic vesicle membrane
(GO:0030670)
Protein binding
(GO:0005515)
Receptor recycling
(GO:0001881)
Recycling endosome
(GO:0055037)
Recycling endosome membrane
(GO:0055038)
Regulated exocytosis
(GO:0045055)
Regulation of endocytic recycling
(GO:2001135)
Regulation of monoatomic anion transport
(GO:0044070)
Regulation of protein localization to cell surface
(GO:2000008)
Synaptic vesicle
(GO:0008021)
Synaptic vesicle membrane
(GO:0030672)
Transferrin transport
(GO:0033572)

Other Information

Proteins

Ras-related protein Rab-11B

Genular Protein ID: 4004299327

Symbol: RB11B_HUMAN

Name: Ras-related protein Rab-11B

UniProtKB Accession Codes:

Q15907 A5YM50 B2R7I4 B4DMK0 D6W671 Q2YDT2 Q5U0I1 Q6FHR0 Q6FI42 Q8NI07

Database IDs:

Citations:

PubMed ID: 7811277

Title: Molecular cloning of two small GTP-binding proteins from human skeletal muscle.

PubMed ID: 7811277

DOI: 10.1006/bbrc.1994.2889

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11495908

Title: Identification and characterization of a family of Rab11-interacting proteins.

PubMed ID: 11495908

DOI: 10.1074/jbc.m104831200

PubMed ID: 14627637

Title: Divergent functions of neuronal Rab11b in Ca2+-regulated versus constitutive exocytosis.

PubMed ID: 14627637

DOI: 10.1523/jneurosci.23-33-10531.2003

PubMed ID: 19029296

Title: Small GTPase determinants for the Golgi processing and plasmalemmal expression of human ether-a-go-go related (hERG) K+ channels.

PubMed ID: 19029296

DOI: 10.1074/jbc.m807289200

PubMed ID: 19244346

Title: Rab11b regulates the apical recycling of the cystic fibrosis transmembrane conductance regulator in polarized intestinal epithelial cells.

PubMed ID: 19244346

DOI: 10.1091/mbc.e08-01-0084

PubMed ID: 21248079

Title: Small GTPase Rab11b regulates degradation of surface membrane L-type Cav1.2 channels.

PubMed ID: 21248079

DOI: 10.1152/ajpcell.00288.2010

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 20717956

Title: Rab11b and its effector Rip11 regulate the acidosis-induced traffic of V-ATPase in salivary ducts.

PubMed ID: 20717956

DOI: 10.1002/jcp.22388

PubMed ID: 21976701

Title: Protrudin serves as an adaptor molecule that connects KIF5 and its cargoes in vesicular transport during process formation.

PubMed ID: 21976701

DOI: 10.1091/mbc.e11-01-0068

PubMed ID: 21255211

Title: Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes.

PubMed ID: 21255211

DOI: 10.1111/j.1600-0854.2011.01165.x

PubMed ID: 22129970

Title: Rab11b regulates the trafficking and recycling of the epithelial sodium channel (ENaC).

PubMed ID: 22129970

DOI: 10.1152/ajprenal.00304.2011

PubMed ID: 22613832

Title: TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes.

PubMed ID: 22613832

DOI: 10.1083/jcb.201111079

PubMed ID: 23572552

Title: ACBD3 interaction with TBC1 domain 22 protein is differentially affected by enteroviral and kobuviral 3A protein binding.

PubMed ID: 23572552

DOI: 10.1128/mbio.00098-13

PubMed ID: 24023390

Title: Large-scale top down proteomics of the human proteome: membrane proteins, mitochondria, and senescence.

PubMed ID: 24023390

DOI: 10.1074/mcp.m113.030114

PubMed ID: 25673879

Title: The Arf and Rab11 effector FIP3 acts synergistically with ASAP1 to direct Rabin8 in ciliary receptor targeting.

PubMed ID: 25673879

DOI: 10.1242/jcs.162925

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 29106825

Title: Recurrent de novo mutations disturbing the GTP/GDP binding pocket of RAB11B cause intellectual disability and a distinctive brain phenotype.

PubMed ID: 29106825

DOI: 10.1016/j.ajhg.2017.09.015

PubMed ID: 30661770

Title: TBC1D8B Loss-of-Function Mutations Lead to X-Linked Nephrotic Syndrome via Defective Trafficking Pathways.

PubMed ID: 30661770

DOI: 10.1016/j.ajhg.2018.12.016

PubMed ID: 31204173

Title: Akt Regulates a Rab11-Effector Switch Required for Ciliogenesis.

PubMed ID: 31204173

DOI: 10.1016/j.devcel.2019.05.022

PubMed ID: 32974215

Title: The Salmonella effector SseK3 targets small Rab GTPases.

PubMed ID: 32974215

DOI: 10.3389/fcimb.2020.00419

PubMed ID: 16545962

Title: The crystal structure of the small GTPase Rab11b reveals critical differences relative to the Rab11a isoform.

PubMed ID: 16545962

DOI: 10.1016/j.jsb.2006.01.007

Sequence Information:

Length: 218
Mass: 24489
Checksum: 8DF146BA39EBD9FF
Sequence:

MGTRDDEYDY LFKVVLIGDS GVGKSNLLSR FTRNEFNLES KSTIGVEFAT RSIQVDGKTI 
KAQIWDTAGQ ERYRAITSAY YRGAVGALLV YDIAKHLTYE NVERWLKELR DHADSNIVIM 
LVGNKSDLRH LRAVPTDEAR AFAEKNNLSF IETSALDSTN VEEAFKNILT EIYRIVSQKQ 
IADRAAHDES PGNNVVDISV PPTTDGQKPN KLQCCQNL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: RAB11B

Associated with

Other Information

Molecular cloning of two small GTP-binding proteins from human skeletal muscle. PubMed ID: 7811277

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and biology of human chromosome 19. PubMed ID: 15057824

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Identification and characterization of a family of Rab11-interacting proteins. PubMed ID: 11495908

Divergent functions of neuronal Rab11b in Ca2+-regulated versus constitutive exocytosis. PubMed ID: 14627637

Small GTPase determinants for the Golgi processing and plasmalemmal expression of human ether-a-go-go related (hERG) K+ channels. PubMed ID: 19029296

Rab11b regulates the apical recycling of the cystic fibrosis transmembrane conductance regulator in polarized intestinal epithelial cells. PubMed ID: 19244346

Small GTPase Rab11b regulates degradation of surface membrane L-type Cav1.2 channels. PubMed ID: 21248079

Initial characterization of the human central proteome. PubMed ID: 21269460

Rab11b and its effector Rip11 regulate the acidosis-induced traffic of V-ATPase in salivary ducts. PubMed ID: 20717956

Protrudin serves as an adaptor molecule that connects KIF5 and its cargoes in vesicular transport during process formation. PubMed ID: 21976701

Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes. PubMed ID: 21255211

Rab11b regulates the trafficking and recycling of the epithelial sodium channel (ENaC). PubMed ID: 22129970

TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes. PubMed ID: 22613832

ACBD3 interaction with TBC1 domain 22 protein is differentially affected by enteroviral and kobuviral 3A protein binding. PubMed ID: 23572552

Large-scale top down proteomics of the human proteome: membrane proteins, mitochondria, and senescence. PubMed ID: 24023390

The Arf and Rab11 effector FIP3 acts synergistically with ASAP1 to direct Rabin8 in ciliary receptor targeting. PubMed ID: 25673879

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Recurrent de novo mutations disturbing the GTP/GDP binding pocket of RAB11B cause intellectual disability and a distinctive brain phenotype. PubMed ID: 29106825

TBC1D8B Loss-of-Function Mutations Lead to X-Linked Nephrotic Syndrome via Defective Trafficking Pathways. PubMed ID: 30661770

Akt Regulates a Rab11-Effector Switch Required for Ciliogenesis. PubMed ID: 31204173

The Salmonella effector SseK3 targets small Rab GTPases. PubMed ID: 32974215

The crystal structure of the small GTPase Rab11b reveals critical differences relative to the Rab11a isoform. PubMed ID: 16545962