Details for: CD8A

Gene ID: 925

Symbol: CD8A

Ensembl ID: ENSG00000153563

Description: CD8 subunit alpha

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 38.2024
    Cell Significance Index: -15.5200
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 3.4237
    Cell Significance Index: 52.9700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.2205
    Cell Significance Index: 55.3200
  • Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
    Fold Change: 1.0887
    Cell Significance Index: 8.1000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.0413
    Cell Significance Index: 22.5600
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 1.0137
    Cell Significance Index: 10.5100
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 0.8794
    Cell Significance Index: 9.1200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.8681
    Cell Significance Index: 165.2100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.7079
    Cell Significance Index: 70.0300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6082
    Cell Significance Index: 549.1700
  • Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
    Fold Change: 0.4319
    Cell Significance Index: 3.3600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.2920
    Cell Significance Index: 7.8100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2229
    Cell Significance Index: 36.2600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2052
    Cell Significance Index: 41.1700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1973
    Cell Significance Index: 21.4600
  • Cell Name: exhausted T cell (CL0011025)
    Fold Change: 0.1926
    Cell Significance Index: 1.5700
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 0.1668
    Cell Significance Index: 1.2000
  • Cell Name: hepatic pit cell (CL2000054)
    Fold Change: 0.1167
    Cell Significance Index: 0.3100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.1104
    Cell Significance Index: 4.1800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.0979
    Cell Significance Index: 4.3300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0956
    Cell Significance Index: 34.3000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0857
    Cell Significance Index: 1.8300
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: 0.0781
    Cell Significance Index: 0.7400
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 0.0616
    Cell Significance Index: 0.5200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0587
    Cell Significance Index: 4.0600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0572
    Cell Significance Index: 11.3500
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: 0.0519
    Cell Significance Index: 0.4200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0087
    Cell Significance Index: 0.2500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0036
    Cell Significance Index: -1.0300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0037
    Cell Significance Index: -0.0800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0048
    Cell Significance Index: -0.1700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0052
    Cell Significance Index: -9.7600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0077
    Cell Significance Index: -14.1900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0094
    Cell Significance Index: -14.4100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0108
    Cell Significance Index: -14.7000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0125
    Cell Significance Index: -9.4900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0136
    Cell Significance Index: -0.3400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0178
    Cell Significance Index: -13.1600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0199
    Cell Significance Index: -10.8700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0227
    Cell Significance Index: -16.6400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0228
    Cell Significance Index: -12.8700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0246
    Cell Significance Index: -15.3500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0248
    Cell Significance Index: -15.7800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0292
    Cell Significance Index: -1.7900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0334
    Cell Significance Index: -15.1600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0471
    Cell Significance Index: -6.0400
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: -0.0483
    Cell Significance Index: -0.4900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0541
    Cell Significance Index: -9.7600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0619
    Cell Significance Index: -13.0300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0631
    Cell Significance Index: -2.0200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0742
    Cell Significance Index: -1.5400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0779
    Cell Significance Index: -13.3000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0810
    Cell Significance Index: -5.4500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0816
    Cell Significance Index: -11.2100
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0846
    Cell Significance Index: -3.6800
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.0977
    Cell Significance Index: -2.8700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1002
    Cell Significance Index: -4.7100
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: -0.1005
    Cell Significance Index: -0.9300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.1011
    Cell Significance Index: -12.4300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1053
    Cell Significance Index: -15.3100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1086
    Cell Significance Index: -11.3100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1101
    Cell Significance Index: -14.2200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1129
    Cell Significance Index: -13.3200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1176
    Cell Significance Index: -13.4700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1223
    Cell Significance Index: -12.4900
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -0.1257
    Cell Significance Index: -1.7100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1313
    Cell Significance Index: -8.0700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1330
    Cell Significance Index: -3.4200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1551
    Cell Significance Index: -11.9100
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.1666
    Cell Significance Index: -2.8300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.1737
    Cell Significance Index: -10.4300
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: -0.1761
    Cell Significance Index: -1.5000
  • Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
    Fold Change: -0.1778
    Cell Significance Index: -1.4400
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.1805
    Cell Significance Index: -2.6400
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.1829
    Cell Significance Index: -2.1600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1925
    Cell Significance Index: -14.3500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1993
    Cell Significance Index: -5.5700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2080
    Cell Significance Index: -13.1100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2213
    Cell Significance Index: -12.4200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2308
    Cell Significance Index: -12.1200
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.2348
    Cell Significance Index: -6.7000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2358
    Cell Significance Index: -8.2600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2474
    Cell Significance Index: -8.1000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2496
    Cell Significance Index: -7.9500
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.2512
    Cell Significance Index: -4.3300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2513
    Cell Significance Index: -16.2100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.2521
    Cell Significance Index: -11.7600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.2562
    Cell Significance Index: -13.3100
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.2792
    Cell Significance Index: -11.4400
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: -0.2819
    Cell Significance Index: -2.8400
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.2904
    Cell Significance Index: -4.4100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2976
    Cell Significance Index: -15.5000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.3006
    Cell Significance Index: -15.1900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.3076
    Cell Significance Index: -4.4100
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.3231
    Cell Significance Index: -8.0600
  • Cell Name: monocyte-derived dendritic cell (CL0011031)
    Fold Change: -0.3498
    Cell Significance Index: -6.0100
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.3713
    Cell Significance Index: -13.6300
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.3986
    Cell Significance Index: -8.4600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.4099
    Cell Significance Index: -8.5800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.4122
    Cell Significance Index: -11.0500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Structure:** The CD8A gene encodes for the alpha subunit of the CD8 molecule, which is composed of two immunoglobulin-like domains (I and II) and a cytoplasmic tail. 2. **Function:** CD8A serves as a coreceptor for the T-cell receptor (TCR), facilitating the recognition of antigens presented by MHC class I molecules on the surface of target cells. 3. **Cellular Expression:** CD8A is expressed on the surface of CD8-positive, alpha-beta T cells, including alpha-beta memory T cells, effector memory CD8-positive T cells, and terminally differentiated activated CD8-positive T cells. 4. **Regulation:** The expression of CD8A is tightly regulated by various transcriptional and post-transcriptional mechanisms, ensuring its proper function in the immune response. **Pathways and Functions:** 1. **Adaptive Immune Response:** CD8A plays a crucial role in the adaptive immune response, mediating the recognition of antigens presented by MHC class I molecules on the surface of target cells. 2. **Antigen Processing and Presentation:** CD8A facilitates the recognition of antigens that have been processed and presented by MHC class I molecules on the surface of antigen-presenting cells (APCs). 3. **Cell Surface Receptor Signaling Pathway:** The CD8A molecule interacts with the TCR, triggering a signaling cascade that regulates T-cell activation, proliferation, and differentiation. 4. **Coreceptor Activity:** CD8A serves as a coreceptor for the TCR, enhancing the affinity of the TCR for MHC class I molecules and facilitating the recognition of antigens. 5. **Cytotoxic T Cell Differentiation:** CD8A is essential for the differentiation of alpha-beta T cells into cytotoxic T cells, which play a critical role in the elimination of infected cells and tumor cells. **Clinical Significance:** 1. **Autoimmune Diseases:** Dysregulation of CD8A expression has been implicated in various autoimmune diseases, including multiple sclerosis and rheumatoid arthritis. 2. **Cancer:** CD8A plays a crucial role in the recognition and elimination of tumor cells, and its dysregulation can contribute to cancer progression. 3. **Immunotherapy:** CD8A is a target for immunotherapeutic interventions, including cancer vaccination and adoptive T-cell therapy. 4. **Infectious Diseases:** CD8A is essential for the recognition and elimination of infected cells, and its dysregulation can contribute to the progression of infectious diseases. In conclusion, CD8A is a critical component of the adaptive immune response, mediating the recognition of antigens presented by MHC class I molecules on the surface of target cells. Its dysregulation has been implicated in various immunological disorders, including autoimmune diseases and cancer, making it a promising target for immunotherapeutic interventions.

Genular Protein ID: 872863526

Symbol: CD8A_HUMAN

Name: T-cell surface glycoprotein CD8 alpha chain

UniProtKB Accession Codes:

P01732 B4DT80 D6W5M8 Q13970 Q4ZG17

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CPTC 1 CTD 1 ChiTaRS 1 ComplexPortal 2 DMDM 1 DNASU 1 DisGeNET 1 EMBL 15 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 18 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 8 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 1 RefSeq 3 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3871356

Title: The isolation and sequence of the gene encoding T8: a molecule defining functional classes of T lymphocytes.

PubMed ID: 3871356

DOI: 10.1016/0092-8674(85)90138-2

PubMed ID: 3936473

Title: Structure of Leu-2/T8 as deduced from the sequence of a cDNA clone.

PubMed ID: 3936473

PubMed ID: 3918796

Title: The T cell differentiation antigen Leu-2/T8 is homologous to immunoglobulin and T cell receptor variable regions.

PubMed ID: 3918796

DOI: 10.1016/0092-8674(85)90207-7

PubMed ID: 2509342

Title: Structure and expression of the gene encoding CD8 alpha chain (Leu-2/T8).

PubMed ID: 2509342

DOI: 10.1007/bf02425282

PubMed ID: 2496167

Title: Alternatively spliced mRNA encodes a secreted form of human CD8 alpha. Characterization of the human CD8 alpha gene.

PubMed ID: 2496167

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 2536941

Title: A secreted form of the human lymphocyte cell surface molecule CD8 arises from alternative splicing.

PubMed ID: 2536941

DOI: 10.1073/pnas.86.3.998

PubMed ID: 6605969

Title: The T8 antigen is a multimeric complex of two distinct subunits on human thymocytes but consists of homomultimeric forms on peripheral blood T lymphocytes.

PubMed ID: 6605969

DOI: 10.1016/s0021-9258(17)43915-9

PubMed ID: 2512251

Title: Phosphorylation and down-regulation of CD4 and CD8 in human CTLs and mouse L cells.

PubMed ID: 2512251

DOI: 10.1007/bf02421181

PubMed ID: 2784196

Title: Polymorphism in the alpha 3 domain of HLA-A molecules affects binding to CD8.

PubMed ID: 2784196

DOI: 10.1038/338345a0

PubMed ID: 1460019

Title: Post-translational processing of an O-glycosylated protein, the human CD8 glycoprotein, during the intracellular transport to the plasma membrane.

PubMed ID: 1460019

DOI: 10.1016/s0021-9258(19)74024-1

PubMed ID: 7923932

Title: A distinctive form of soluble CD8 is secreted by stimulated CD8+ cells in HIV-1-infected and high-risk individuals.

PubMed ID: 7923932

DOI: 10.1006/clin.1994.1195

PubMed ID: 12853576

Title: Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G.

PubMed ID: 12853576

DOI: 10.1073/pnas.1431057100

PubMed ID: 16236125

Title: Ligation of CD8alpha on human natural killer cells prevents activation-induced apoptosis and enhances cytolytic activity.

PubMed ID: 16236125

DOI: 10.1111/j.1365-2567.2005.02235.x

PubMed ID: 17678538

Title: CD8 alpha is expressed by human monocytes and enhances Fc gamma R-dependent responses.

PubMed ID: 17678538

DOI: 10.1186/1471-2172-8-12

PubMed ID: 17341584

Title: CD8 Raft localization is induced by its assembly into CD8alpha beta heterodimers, Not CD8alpha alpha homodimers.

PubMed ID: 17341584

DOI: 10.1074/jbc.m701027200

PubMed ID: 23657257

Title: Immune surveillance by CD8alphaalpha+ skin-resident T cells in human herpes virus infection.

PubMed ID: 23657257

DOI: 10.1038/nature12110

PubMed ID: 26082771

Title: A subset of human plasmacytoid dendritic cells expresses CD8alpha upon exposure to herpes simplex virus type 1.

PubMed ID: 26082771

DOI: 10.3389/fmicb.2015.00557

PubMed ID: 1547508

Title: Crystal structure of a soluble form of the human T cell coreceptor CD8 at 2.6-A resolution.

PubMed ID: 1547508

DOI: 10.1016/0092-8674(92)90085-q

PubMed ID: 9177355

Title: Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2.

PubMed ID: 9177355

DOI: 10.1038/42523

PubMed ID: 14500983

Title: A zinc clasp structure tethers Lck to T cell coreceptors CD4 and CD8.

PubMed ID: 14500983

DOI: 10.1126/science.1085643

PubMed ID: 11435463

Title: Familial CD8 deficiency due to a mutation in the CD8 alpha gene.

PubMed ID: 11435463

DOI: 10.1172/jci10993

PubMed ID: 17658607

Title: Gly111Ser mutation in CD8A gene causing CD8 immunodeficiency is found in Spanish Gypsies.

PubMed ID: 17658607

DOI: 10.1016/j.molimm.2007.05.022

Sequence Information:

  • Length: 235
  • Mass: 25729
  • Checksum: FCCA29BAA73726BB
  • Sequence:
    • MALPVTALLL PLALLLHAAR PSQFRVSPLD RTWNLGETVE LKCQVLLSNP TSGCSWLFQP 
RGAAASPTFL LYLSQNKPKA AEGLDTQRFS GKRLGDTFVL TLSDFRRENE GYYFCSALSN 
SIMYFSHFVP VFLPAKPTTT PAPRPPTPAP TIASQPLSLR PEACRPAAGG AVHTRGLDFA 
CDIYIWAPLA GTCGVLLLSL VITLYCNHRN RRRVCKCPRP VVKSGDKPSL SARYV

Genular Protein ID: 3883293718

Symbol: Q8TAW8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8TAW8

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 3 SAM 2 SMART 2 SMR 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 235
  • Mass: 25669
  • Checksum: FCDFC9B5472D26BB
  • Sequence:
    • MALPVTALLL PLALLLHAAR PSQFRVSPLD RTWNLGETVE LKCQVLLSNP TSGCSWLFQP 
RGAAASPTFL LYLSQNKPKA AEGLDTQRFS GKRLGDTFVL TLSDFRRENE GCYFCSALSN 
SIMYFSHFVP VFLPAKPTTT PAPRPPTPAP TIASQPLSLR PEACRPAAGG AVHTRGLDFA 
CDIYIWAPLA GTCGVLLLSL VITLYCNHRN RRRVCKCPRP VVKSGDKPSL SARYV

Genular Protein ID: 3569746370

Symbol: Q6ZVS2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6ZVS2

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 2 SAM 2 SUPFAM 1

Sequence Information:

  • Length: 152
  • Mass: 16713
  • Checksum: 6911F40F86122E02
  • Sequence:
    • MRNQAPGRPK GATFPPRRPT GSRAPPLAPE LRAKQRPGER VMALPVTALL LPLALLLHAA 
RPSQFRVSPL DRTWNLGETV ELKCQVLLSN PTSGCSWLFQ PRGAAASPTF LLYLSQNKPK 
AAEGLDTQRF SGKRLGDTFV LTLSDFRREN EG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.