Details for: CYTH2

Gene ID: 9266

Symbol: CYTH2

Ensembl ID: ENSG00000105443

Description: cytohesin 2

Associated with

Other Information

Genular Protein ID: 3380183480

Symbol: CYH2_HUMAN

Name: Cytohesin-2

UniProtKB Accession Codes:

Q99418 A8K8P0 Q8IXY9 Q92958

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 2 CTD 1 ChEBI 7 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 5 EMBL 5 EPD 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 14 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 13 PDBsum 11 PRO 1 PROSITE 2 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 SASBDB 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8945478

Title: A human exchange factor for ARF contains Sec7- and pleckstrin-homology domains.

PubMed ID: 8945478

DOI: 10.1038/384481a0

PubMed ID: 9417041

Title: ARNO is a guanine nucleotide exchange factor for ADP-ribosylation factor 6.

PubMed ID: 9417041

DOI: 10.1074/jbc.273.1.23

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17623778

Title: The calcium-sensing receptor changes cell shape via a beta-arrestin-1 ARNO ARF6 ELMO protein network.

PubMed ID: 17623778

DOI: 10.1242/jcs.03469

PubMed ID: 17398095

Title: The Arl4 family of small G proteins can recruit the cytohesin Arf6 exchange factors to the plasma membrane.

PubMed ID: 17398095

DOI: 10.1016/j.cub.2007.03.007

PubMed ID: 25326380

Title: Arf6 guanine nucleotide exchange factor cytohesin-2 binds to CCDC120 and is transported along neurites to mediate neurite growth.

PubMed ID: 25326380

DOI: 10.1074/jbc.m114.575787

PubMed ID: 29420262

Title: C1orf106 is a colitis risk gene that regulates stability of epithelial adherens junctions.

PubMed ID: 29420262

DOI: 10.1126/science.aan0814

PubMed ID: 9476900

Title: Structure of the guanine nucleotide exchange factor Sec7 domain of human ARNO and analysis of the interaction with ARF GTPase.

PubMed ID: 9476900

DOI: 10.1016/s0092-8674(00)80933-2

PubMed ID: 9510256

Title: Structure of the Sec7 domain of the Arf exchange factor ARNO.

PubMed ID: 9510256

DOI: 10.1038/32210

PubMed ID: 14654833

Title: Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor.

PubMed ID: 14654833

DOI: 10.1038/nature02197

Sequence Information:

  • Length: 400
  • Mass: 46546
  • Checksum: 70441A58483BD0E1
  • Sequence:
    • MEDGVYEPPD LTPEERMELE NIRRRKQELL VEIQRLREEL SEAMSEVEGL EANEGSKTLQ 
RNRKMAMGRK KFNMDPKKGI QFLVENELLQ NTPEEIARFL YKGEGLNKTA IGDYLGEREE 
LNLAVLHAFV DLHEFTDLNL VQALRQFLWS FRLPGEAQKI DRMMEAFAQR YCLCNPGVFQ 
STDTCYVLSF AVIMLNTSLH NPNVRDKPGL ERFVAMNRGI NEGGDLPEEL LRNLYDSIRN 
EPFKIPEDDG NDLTHTFFNP DREGWLLKLG GGRVKTWKRR WFILTDNCLY YFEYTTDKEP 
RGIIPLENLS IREVDDPRKP NCFELYIPNN KGQLIKACKT EADGRVVEGN HMVYRISAPT 
QEEKDEWIKS IQAAVSVDPF YEMLAARKKR ISVKKKQEQP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.