Details for: ADGRG1

Gene ID: 9289

Symbol: ADGRG1

Ensembl ID: ENSG00000205336

Description: adhesion G protein-coupled receptor G1

Associated with

Other Information

Genular Protein ID: 3059645198

Symbol: AGRG1_HUMAN

Name: Adhesion G-protein coupled receptor G1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10049584

Title: GPR56, a novel secretin-like human G-protein-coupled receptor gene.

PubMed ID: 10049584

DOI: 10.1006/geno.1998.5644

PubMed ID: 10100861

Title: TM7XN1, a novel human EGF-TM7 like protein, detected with mRNA differential display using human melanoma cell lines with different metastatic potential.

PubMed ID: 10100861

DOI: 10.1016/s0014-5793(99)00230-6

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15340161

Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.

PubMed ID: 15340161

DOI: 10.1110/ps.04682504

PubMed ID: 15004227

Title: Dynamic regulation of a GPCR-tetraspanin-G protein complex on intact cells: central role of CD81 in facilitating GPR56-Galpha q/11 association.

PubMed ID: 15004227

DOI: 10.1091/mbc.e03-12-0886

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16757564

Title: GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis.

PubMed ID: 16757564

DOI: 10.1073/pnas.0602681103

PubMed ID: 19572147

Title: Splicing variants of the orphan G-protein-coupled receptor GPR56 regulate the activity of transcription factors associated with tumorigenesis.

PubMed ID: 19572147

DOI: 10.1007/s00432-009-0635-z

PubMed ID: 21724588

Title: GPR56 Regulates VEGF production and angiogenesis during melanoma progression.

PubMed ID: 21724588

DOI: 10.1158/0008-5472.can-10-4543

PubMed ID: 21349848

Title: Disease-associated GPR56 mutations cause bilateral frontoparietal polymicrogyria via multiple mechanisms.

PubMed ID: 21349848

DOI: 10.1074/jbc.m110.183830

PubMed ID: 21708946

Title: The N terminus of the adhesion G protein-coupled receptor GPR56 controls receptor signaling activity.

PubMed ID: 21708946

DOI: 10.1074/jbc.m111.247973

PubMed ID: 22333914

Title: A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis.

PubMed ID: 22333914

DOI: 10.1038/emboj.2012.26

PubMed ID: 22238662

Title: Disease-associated mutations prevent GPR56-collagen III interaction.

PubMed ID: 22238662

DOI: 10.1371/journal.pone.0029818

PubMed ID: 24531968

Title: Evolutionarily dynamic alternative splicing of GPR56 regulates regional cerebral cortical patterning.

PubMed ID: 24531968

DOI: 10.1126/science.1244392

PubMed ID: 25918380

Title: Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist.

PubMed ID: 25918380

DOI: 10.1073/pnas.1421785112

PubMed ID: 26710850

Title: Stalk-dependent and stalk-independent signaling by the adhesion G protein-coupled receptors GPR56 (ADGRG1) and BAI1 (ADGRB1).

PubMed ID: 26710850

DOI: 10.1074/jbc.m115.689349

PubMed ID: 27068534

Title: Heparin interacts with adhesion-GPCR GPR56/ADGRG1, reduces receptor shedding, and promotes cell adhesion and motility.

PubMed ID: 27068534

DOI: 10.1242/jcs.174458

PubMed ID: 28258187

Title: Bi-allelic variants in COL3A1 encoding the ligand to GPR56 are associated with cobblestone-like cortical malformation, white matter changes and cerebellar cysts.

PubMed ID: 28258187

DOI: 10.1136/jmedgenet-2016-104421

PubMed ID: 15044805

Title: G protein-coupled receptor-dependent development of human frontal cortex.

PubMed ID: 15044805

DOI: 10.1126/science.1092780

PubMed ID: 16240336

Title: Genotype-phenotype analysis of human frontoparietal polymicrogyria syndromes.

PubMed ID: 16240336

DOI: 10.1002/ana.20616

PubMed ID: 21723461

Title: A novel GPR56 mutation causes bilateral frontoparietal polymicrogyria.

PubMed ID: 21723461

DOI: 10.1016/j.pediatrneurol.2011.02.004

PubMed ID: 24949629

Title: Mechanism for adhesion G protein-coupled receptor GPR56-mediated RhoA activation induced by collagen III stimulation.

PubMed ID: 24949629

DOI: 10.1371/journal.pone.0100043

Sequence Information:

  • Length: 693
  • Mass: 77738
  • Checksum: 801C8E62666A5155
  • Sequence:
  • MTPQSLLQTT LFLLSLLFLV QGAHGRGHRE DFRFCSQRNQ THRSSLHYKP TPDLRISIEN 
    SEEALTVHAP FPAAHPASRS FPDPRGLYHF CLYWNRHAGR LHLLYGKRDF LLSDKASSLL 
    CFQHQEESLA QGPPLLATSV TSWWSPQNIS LPSAASFTFS FHSPPHTAAH NASVDMCELK 
    RDLQLLSQFL KHPQKASRRP SAAPASQQLQ SLESKLTSVR FMGDMVSFEE DRINATVWKL 
    QPTAGLQDLH IHSRQEEEQS EIMEYSVLLP RTLFQRTKGR SGEAEKRLLL VDFSSQALFQ 
    DKNSSQVLGE KVLGIVVQNT KVANLTEPVV LTFQHQLQPK NVTLQCVFWV EDPTLSSPGH 
    WSSAGCETVR RETQTSCFCN HLTYFAVLMV SSVEVDAVHK HYLSLLSYVG CVVSALACLV 
    TIAAYLCSRV PLPCRRKPRD YTIKVHMNLL LAVFLLDTSF LLSEPVALTG SEAGCRASAI 
    FLHFSLLTCL SWMGLEGYNL YRLVVEVFGT YVPGYLLKLS AMGWGFPIFL VTLVALVDVD 
    NYGPIILAVH RTPEGVIYPS MCWIRDSLVS YITNLGLFSL VFLFNMAMLA TMVVQILRLR 
    PHTQKWSHVL TLLGLSLVLG LPWALIFFSF ASGTFQLVVL YLFSIITSFQ GFLIFIWYWS 
    MRLQARGGPS PLKSNSDSAR LPISSGSTSS SRI

Genular Protein ID: 2823923500

Symbol: A0A0S2Z517_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 26871637

Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

PubMed ID: 26871637

DOI: 10.1016/j.cell.2016.01.029

Sequence Information:

  • Length: 687
  • Mass: 77072
  • Checksum: BB8712796ED1B99B
  • Sequence:
  • MTPQSLLQTT LFLLSLLFLV QGAHGRGHRE DFRFCSQRNQ THRSSLHYKP TPDLRISIEN 
    SEEALTVHAP FPAAHPASRS FPDPRGLYHF CLYWNRHAGR LHLLYGKRDF LLSDKASSLL 
    CFQHQEESLA QGPPLLATSV TSWWSPQNIS LPSAASFTFS FHSPPHTAAH NASVDMCELK 
    RDLQLLSQFL KHPQKASRRP SAAPASQQLQ SLESKLTSVR FMGDMVSFEE DRINATVWKL 
    QPTAGLQDLH IHSRQEEEQS EIMEYSVLLP RTLFQRTKGR SGEAEKRLLL VDFSSQALFQ 
    DKNSSQVLGE KVLGIVVQNT KVANLTEPVV LTFQHQLQPK NVTLQCVFWV EDPTLSSPGH 
    WSSAGCETVR RETQTSCFCN HLTYFAVLMV SSVEVDAVHK HYLSLLSYVG CVVSALACLV 
    TIAAYLCSRR KPRDYTIKVH MNLLLAVFLL DTSFLLSEPV ALTGSEAGCR ASAIFLHFSL 
    LTCLSWMGLE GYNLYRLVVE VFGTYVPGYL LKLSAMGWGF PIFLVTLVAL VDVDNYGPII 
    LAVHRTPEGV IYPSMCWIRD SLVSYITNLG LFSLVFLFNM AMLATMVVQI LRLRPHTQKW 
    SHVLTLLGLS LVLGLPWALI FFSFASGTFQ LVVLYLFSII TSFQGFLIFI WYWSMRLQAR 
    GGPSPLKSNS DSARLPISSG STSSSRI

Genular Protein ID: 2429527920

Symbol: B4DM06_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 512
  • Mass: 57473
  • Checksum: 8211690301F82BA7
  • Sequence:
  • MCELKRDLQL LSQFLKHPQK ASRRPSAAPA SQQLQSLESK LTSVRFMGDM VSFEEDRINA 
    TVWKLQPTAG LQDLHIHSRQ EEEQSEIMEY SVLLPRTLFQ RTKGRRGEAE KRLLLVDFSS 
    QALFQDKNSS QVLGEKVLGI VVQNTKVANL TEPVVLTFQH QLQPKNVTLQ CVFWVEDPTL 
    SSPGHWSSAG CETVRRETQT SCFCNHLTYF AVLMVSSVEV DAVHKHYLSL LSYVGCVVSA 
    LACLVTIAAY LCSRRKPRDY TIKVHMNLLL AVFLLDTSFL LSEPVALTGS EVGCRASAIF 
    LHFSLLTCLS WMGLEGYNLY RLVVEVFGTY VPGYLLKLSA MGWGFPIFLV TLVALVDVDN 
    YGPIILAVHR TPEGVIYPSM CWIRDSLVSY ITNLGLFSLV FLFNMAMLAT MVVQILRLRP 
    HTQKWSHVLT LLGLSLVLGL PWALIFFSFA SGTFQLVVLY LFSIITSFQG FLIFIWYWSM 
    RLQARGGPSP LKSNSDSARL PISSGSTSSS RI

Genular Protein ID: 1107374964

Symbol: B3KQV4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16303743

Title: Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

PubMed ID: 16303743

DOI: 10.1093/dnares/12.2.117

Sequence Information:

  • Length: 687
  • Mass: 77012
  • Checksum: FD6C108411924665
  • Sequence:
  • MTPQSLLQTT LFLLSLLFLV QGAHGRGHRE DFRFCSQRNQ THRSSLHYKP TPDLRISIEN 
    SEEALTVHAP FPAAHPASRS FPDPRGLYHF CLYWNRHAGR LHLLYGKRDF LLSDKASSLL 
    CFQHQEESLA QGPPLLATSV TSWWSPQNIS LPSAASFTFS FHSPPHTAAH NASVDMCELK 
    RDLQLLSQFL KHPQKASRRP SAAPASQQLQ SLESKLTSVR FMGDMVSFEE DRINATVWKL 
    QPTAGLQDLH IHSRQEEEQS EIMEYSVLLP RTLFQRTKGR SGEAEKRLLL VDFSSQALFQ 
    DKNSSHVLGE KVLGIVVQNT KVANLTEPVV LTFQHQLQPK NVTLQCVFWV EDPTLSSPGH 
    WSSAGCETVR SETQTSCFCN HLTYFAVLMV SSVEVDAVHK HYLSLLSYVG CVVSALACLV 
    TIAAYLCSRR KPRDYTIKVH MNLLLAVFLL DTSFLLSEPV ALTGSEAGCR ASAIFLHFSL 
    LTCLSWMGLE GYNLYRLVVE VFGTYVPGYL LKLSAMGWGF PIFLVTLVAL VDVDNYGPII 
    LAVHRTPEGV IYPSMCWIRD SLVSYITNLG LFSLVFLFNM AMLATMVVQI LRLRPHTQKW 
    SHVLTLLGLS LVLGLPWALI FFSFASGTFQ LVVLYLFSII TSFQGFLIFI WYWSMRLQAR 
    GGPSPLKSNS DSARLPISSG STSSSRI

Genular Protein ID: 2074965744

Symbol: B3KQN7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16303743

Title: Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

PubMed ID: 16303743

DOI: 10.1093/dnares/12.2.117

Sequence Information:

  • Length: 687
  • Mass: 77100
  • Checksum: 51E012735281B99C
  • Sequence:
  • MTPQSLLQTT LFLLSLLFLV QGAHGRGHRE DFRFCSQRNQ THRSSLHYKP TPDLRISIEN 
    SEEALTVHAP FPAAHPASRS FPDPRGLYHF CLYWNRHAGR LHLLYGKRDF LLSDKASSLL 
    CFQHQEESLA QGPPLLATSV TSWWSPQNIS LPSAASFTFS FHSPPHTAAH NASVDMCELK 
    RDLQLLSQFL KHPQKASRRP SAAPASQQLQ SLESKLTSVR FMGDMVSFEE DRINATVWKL 
    QPTAGLQDLH IHSRQEEEQS EIMEYSVLLP RTLFQRTKGR SGEAEKRLLL VDFSSQALFQ 
    DKNSSQVLGE KVLGIVVQNT KVANLTEPVV LTFQHQLQPK NVTLQCVFWV EDPTLSSPGH 
    WSSAGCETVR RETQTSCFCN HLTYFAVLMV SSVEVDAVHK HYLSLLSYVG CVVSALACLV 
    TIAVYLCSRR KPRDYTIKVH MNLLLAVFLL DTSFLLSEPV ALTGSEAGCR ASAIFLHFSL 
    LTCLSWMGLE GYNLYRLVVE VFGTYVPGYL LKLSAMGWGF PIFLVTLVAL VDVDNYGPII 
    LAVHRTPEGV IYPSMCWIRD SLVSYITNLG LFSLVFLFNM AMLATMVVQI LRLRPHTQKW 
    SHVLTLLGLS LVLGLPWALI FFSFASGTFQ LVVLYLFSII TSFQGFLIFI WYWSMRLQAR 
    GGPSPLKSNS DSARLPISSG STSSSRI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.