Details for: CD14

Gene ID: 929

Symbol: CD14

Ensembl ID: ENSG00000170458

Description: CD14 molecule

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 128.3228
    Cell Significance Index: -19.9600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 80.6250
    Cell Significance Index: -20.4500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 52.4545
    Cell Significance Index: -21.3100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 45.8411
    Cell Significance Index: -23.5800
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 29.7205
    Cell Significance Index: 431.5000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 22.6134
    Cell Significance Index: -21.5900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 16.0590
    Cell Significance Index: -19.8000
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 11.6415
    Cell Significance Index: 215.1700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 6.7492
    Cell Significance Index: -20.7300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.1317
    Cell Significance Index: -20.2500
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 4.4178
    Cell Significance Index: 68.3500
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 2.9025
    Cell Significance Index: 12.0800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 2.3569
    Cell Significance Index: 109.8900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 2.0513
    Cell Significance Index: 202.9200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.7146
    Cell Significance Index: 221.5200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.0721
    Cell Significance Index: 174.3700
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 0.9617
    Cell Significance Index: 7.7900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.9259
    Cell Significance Index: 100.7100
  • Cell Name: salivary gland glandular cell (CL1001596)
    Fold Change: 0.9199
    Cell Significance Index: 5.1200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.7111
    Cell Significance Index: 15.1500
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.5749
    Cell Significance Index: 9.6900
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.5142
    Cell Significance Index: 6.3600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.4325
    Cell Significance Index: 20.3300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.4320
    Cell Significance Index: 32.2000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.3923
    Cell Significance Index: 23.5500
  • Cell Name: seromucus secreting cell (CL0000159)
    Fold Change: 0.2589
    Cell Significance Index: 5.4000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.2183
    Cell Significance Index: 11.3700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.2069
    Cell Significance Index: 41.0700
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.1992
    Cell Significance Index: 2.9400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0726
    Cell Significance Index: 13.8100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0582
    Cell Significance Index: 2.6400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.0572
    Cell Significance Index: 5.8400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0057
    Cell Significance Index: -0.2000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0060
    Cell Significance Index: -4.4200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0083
    Cell Significance Index: -3.6700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0089
    Cell Significance Index: -16.8500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0090
    Cell Significance Index: -0.2600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0092
    Cell Significance Index: -0.2300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0097
    Cell Significance Index: -0.2100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0099
    Cell Significance Index: -6.1900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0138
    Cell Significance Index: -25.5100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0155
    Cell Significance Index: -8.7400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0167
    Cell Significance Index: -25.7300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0181
    Cell Significance Index: -13.6800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0193
    Cell Significance Index: -26.3000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0273
    Cell Significance Index: -14.8900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0285
    Cell Significance Index: -0.7600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0305
    Cell Significance Index: -22.3400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0312
    Cell Significance Index: -19.8000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0402
    Cell Significance Index: -14.4300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0445
    Cell Significance Index: -20.1900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0476
    Cell Significance Index: -10.0200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0486
    Cell Significance Index: -13.9800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0609
    Cell Significance Index: -8.3600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0646
    Cell Significance Index: -12.9500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0794
    Cell Significance Index: -13.5600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0830
    Cell Significance Index: -14.9700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0925
    Cell Significance Index: -4.6700
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1009
    Cell Significance Index: -1.5200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1053
    Cell Significance Index: -13.5000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1152
    Cell Significance Index: -16.7500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.1240
    Cell Significance Index: -15.2500
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.1299
    Cell Significance Index: -5.3200
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.1337
    Cell Significance Index: -1.0900
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1522
    Cell Significance Index: -17.3700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1532
    Cell Significance Index: -17.8500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1568
    Cell Significance Index: -8.2300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1883
    Cell Significance Index: -14.4500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1930
    Cell Significance Index: -22.7600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1954
    Cell Significance Index: -20.3500
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.1986
    Cell Significance Index: -1.2000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2041
    Cell Significance Index: -23.3900
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.2054
    Cell Significance Index: -2.7300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2083
    Cell Significance Index: -14.7300
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.2207
    Cell Significance Index: -4.3200
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.2215
    Cell Significance Index: -3.2400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2247
    Cell Significance Index: -13.8100
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2695
    Cell Significance Index: -7.2100
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.2756
    Cell Significance Index: -4.8700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2846
    Cell Significance Index: -22.5400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2963
    Cell Significance Index: -9.4900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3175
    Cell Significance Index: -21.3500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.3180
    Cell Significance Index: -16.5200
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.3190
    Cell Significance Index: -2.9700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3275
    Cell Significance Index: -20.6400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.3536
    Cell Significance Index: -22.8100
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.3570
    Cell Significance Index: -3.6500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3676
    Cell Significance Index: -22.5400
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: -0.3914
    Cell Significance Index: -3.0900
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: -0.4233
    Cell Significance Index: -3.7000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.4327
    Cell Significance Index: -24.2800
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.4616
    Cell Significance Index: -20.0700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.4786
    Cell Significance Index: -9.3400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.4960
    Cell Significance Index: -21.9400
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.5139
    Cell Significance Index: -18.8700
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: -0.5301
    Cell Significance Index: -4.4800
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: -0.5392
    Cell Significance Index: -3.1100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.5637
    Cell Significance Index: -16.1600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.5804
    Cell Significance Index: -21.9800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.5915
    Cell Significance Index: -20.7200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Expression**: CD14 is expressed on the surface of various immune cells, including classical monocytes, myeloid leukocytes, lung macrophages, Kupffer cells, and blood cells. 2. **Recognition**: CD14 recognizes and binds to a wide range of microbial components, including LPS, lipoteichoic acid, and diacyl bacterial lipopeptides. 3. **Signaling**: Upon binding, CD14 recruits and activates downstream signaling molecules, including MyD88, TRAF6, and IRAK2, which ultimately trigger the production of pro-inflammatory cytokines. 4. **Function**: CD14 plays a crucial role in the innate immune response against bacterial and fungal pathogens, and is involved in the activation of immune cells, including neutrophils and macrophages. **Pathways and Functions** 1. **Activation of IRF3, IRF7 mediated by TBK1, IKBKE**: CD14 signaling activates the IRF3/IRF7 pathway, which is involved in the production of type I IFNs and the regulation of immune responses. 2. **Adaptive Immune System**: CD14 is also involved in the regulation of adaptive immune responses, including the activation of T cells and the production of cytokines. 3. **Antigen Processing-Cross Presentation**: CD14 is involved in the processing and presentation of antigens to CD4+ T cells, which is crucial for the induction of adaptive immune responses. 4. **Apoptosis**: CD14 signaling can also induce apoptosis in certain cell types, including neutrophils and macrophages. 5. **Caspase Activation via Death Receptors in the Presence of Ligand**: CD14 signaling can activate caspases, which are essential for the induction of apoptosis. 6. **Caspase Activation via Extrinsic Apoptotic Signaling Pathway**: CD14 signaling can also activate caspases via the extrinsic apoptotic signaling pathway. 7. **Cell Surface Pattern Recognition Receptor Signaling Pathway**: CD14 is a member of the pattern recognition receptor family and is involved in the recognition of microbial components. 8. **Cell Surface Receptor Signaling Pathway**: CD14 signaling involves the activation of downstream signaling molecules, including MyD88 and TRAF6. **Clinical Significance** 1. **Infectious Diseases**: CD14 plays a crucial role in the innate immune response against bacterial and fungal pathogens, and its dysfunction has been implicated in various infectious diseases, including sepsis and tuberculosis. 2. **Immunodeficiency Disorders**: Mutations in the CD14 gene have been associated with immunodeficiency disorders, including chronic granulomatous disease and familial hyper IgE syndrome. 3. **Autoimmune Diseases**: CD14 signaling has also been implicated in the pathogenesis of autoimmune diseases, including rheumatoid arthritis and lupus. 4. **Cancer**: CD14 has been shown to play a role in the progression of certain types of cancer, including breast and lung cancer. 5. **Vaccine Development**: CD14 is a target for vaccine development, as it is involved in the recognition and processing of antigens from pathogens. In conclusion, CD14 is a critical component of the innate immune response, and its dysfunction has been implicated in various diseases, including infectious diseases, immunodeficiency disorders, autoimmune diseases, and cancer. Further research is needed to fully understand the role of CD14 in human health and disease.

Genular Protein ID: 3628415192

Symbol: CD14_HUMAN

Name: Myeloid cell-specific leucine-rich glycoprotein

UniProtKB Accession Codes:

P08571 Q53XT5 Q96FR6 Q96L99 Q9UNS3

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CPTAC 1 CPTC 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 9 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 40 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PIRSF 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 20 RefSeq 4 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3385210

Title: The monocyte differentiation antigen, CD14, is anchored to the cell membrane by a phosphatidylinositol linkage.

PubMed ID: 3385210

PubMed ID: 2453848

Title: Nucleotide sequence of the gene encoding the monocyte differentiation antigen, CD14.

PubMed ID: 2453848

DOI: 10.1093/nar/16.9.4173

PubMed ID: 2472171

Title: Mouse and human CD14 (myeloid cell-specific leucine-rich glycoprotein) primary structure deduced from cDNA clones.

PubMed ID: 2472171

DOI: 10.1016/0167-4781(80)90012-3

PubMed ID: 2462937

Title: Monocyte antigen CD14 is a phospholipid anchored membrane protein.

PubMed ID: 2462937

PubMed ID: 18810425

Title: Natural selection in the TLR-related genes in the course of primate evolution.

PubMed ID: 18810425

DOI: 10.1007/s00251-008-0332-0

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2779588

Title: Structural relationship between the soluble and membrane-bound forms of human monocyte surface glycoprotein CD14.

PubMed ID: 2779588

DOI: 10.1016/0161-5890(89)90048-5

PubMed ID: 1698311

Title: CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein.

PubMed ID: 1698311

DOI: 10.1126/science.1698311

PubMed ID: 1718034

Title: CD14 and immune response to lipopolysaccharide.

PubMed ID: 1718034

DOI: 10.1126/science.1718034

PubMed ID: 8612135

Title: Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice.

PubMed ID: 8612135

DOI: 10.1016/s1074-7613(00)80254-x

PubMed ID: 11274165

Title: Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. transfer from CD14 to TLR4 and MD-2.

PubMed ID: 11274165

DOI: 10.1074/jbc.m009164200

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 16880211

Title: Membrane sorting of toll-like receptor (TLR)-2/6 and TLR2/1 heterodimers at the cell surface determines heterotypic associations with CD36 and intracellular targeting.

PubMed ID: 16880211

DOI: 10.1074/jbc.m602794200

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19838169

Title: Enrichment of glycopeptides for glycan structure and attachment site identification.

PubMed ID: 19838169

DOI: 10.1038/nmeth.1392

PubMed ID: 20133493

Title: Lipopolysaccharide-binding protein-mediated Toll-like receptor 4 dimerization enables rapid signal transduction against lipopolysaccharide stimulation on membrane-associated CD14-expressing cells.

PubMed ID: 20133493

DOI: 10.1093/intimm/dxq005

PubMed ID: 22265692

Title: Follistatin-related protein/follistatin-like 1 evokes an innate immune response via CD14 and toll-like receptor 4.

PubMed ID: 22265692

DOI: 10.1016/j.febslet.2012.01.010

PubMed ID: 23880187

Title: CD14 and TLR4 mediate cytokine release promoted by electronegative LDL in monocytes.

PubMed ID: 23880187

DOI: 10.1016/j.atherosclerosis.2013.05.011

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25497142

Title: 27-Hydroxycholesterol up-regulates CD14 and predisposes monocytic cells to superproduction of CCL2 in response to lipopolysaccharide.

PubMed ID: 25497142

DOI: 10.1016/j.bbadis.2014.12.003

PubMed ID: 25965346

Title: SP-R210 (Myo18A) isoforms as intrinsic modulators of macrophage priming and activation.

PubMed ID: 25965346

DOI: 10.1371/journal.pone.0126576

PubMed ID: 23264655

Title: The crystal structure of human soluble CD14 reveals a bent solenoid with a hydrophobic amino-terminal pocket.

PubMed ID: 23264655

DOI: 10.4049/jimmunol.1202446

Sequence Information:

  • Length: 375
  • Mass: 40076
  • Checksum: 1746CDB41F394F8D
  • Sequence:
    • MERASCLLLL LLPLVHVSAT TPEPCELDDE DFRCVCNFSE PQPDWSEAFQ CVSAVEVEIH 
AGGLNLEPFL KRVDADADPR QYADTVKALR VRRLTVGAAQ VPAQLLVGAL RVLAYSRLKE 
LTLEDLKITG TMPPLPLEAT GLALSSLRLR NVSWATGRSW LAELQQWLKP GLKVLSIAQA 
HSPAFSCEQV RAFPALTSLD LSDNPGLGER GLMAALCPHK FPAIQNLALR NTGMETPTGV 
CAALAAAGVQ PHSLDLSHNS LRATVNPSAP RCMWSSALNS LNLSFAGLEQ VPKGLPAKLR 
VLDLSCNRLN RAPQPDELPE VDNLTLDGNP FLVPGTALPH EGSMNSGVVP ACARSTLSVG 
VSGTLVLLQG ARGFA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.