SOCS6 | ENSG00000170677 | NCBI 9306

Details for: SOCS6

Gene ID: 9306

Symbol: SOCS6

Ensembl ID: ENSG00000170677

Description: suppressor of cytokine signaling 6

Associated with

Cytokine signaling in immune system
(R-HSA-1280215)
Flt3 signaling
(R-HSA-9607240)
Immune system
(R-HSA-168256)
Metabolism of proteins
(R-HSA-392499)
Neddylation
(R-HSA-8951664)
Negative regulation of flt3
(R-HSA-9706369)
Post-translational protein modification
(R-HSA-597592)
Regulation of kit signaling
(R-HSA-1433559)
Signaling by receptor tyrosine kinases
(R-HSA-9006934)
Signaling by scf-kit
(R-HSA-1433557)
Signal transduction
(R-HSA-162582)
1-phosphatidylinositol-3-kinase regulator activity
(GO:0046935)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Defense response
(GO:0006952)
Immunological synapse
(GO:0001772)
Intracellular signal transduction
(GO:0035556)
Negative regulation of signal transduction
(GO:0009968)
Negative regulation of t cell activation
(GO:0050868)
Phosphatidylinositol 3-kinase complex
(GO:0005942)
Phosphatidylinositol phosphate biosynthetic process
(GO:0046854)
Proteasomal protein catabolic process
(GO:0010498)
Protein binding
(GO:0005515)
Protein ubiquitination
(GO:0016567)
Receptor signaling pathway via jak-stat
(GO:0007259)
Regulation of growth
(GO:0040008)

Other Information

Proteins

Suppressor of cytokine signaling 6

Genular Protein ID: 1468921282

Symbol: SOCS6_HUMAN

Name: Suppressor of cytokine signaling 6

UniProtKB Accession Codes:

O14544 Q8WUM3

Database IDs:

Citations:

PubMed ID: 9344848

Title: Cloning and characterization of novel CIS family genes.

PubMed ID: 9344848

DOI: 10.1006/bbrc.1997.7484

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15526160

Title: Signal transduction via the stem cell factor receptor/c-Kit.

PubMed ID: 15526160

DOI: 10.1007/s00018-004-4189-6

PubMed ID: 21030588

Title: Structural basis for c-KIT inhibition by the suppressor of cytokine signaling 6 (SOCS6) ubiquitin ligase.

PubMed ID: 21030588

DOI: 10.1074/jbc.m110.173526

Sequence Information:

Length: 535
Mass: 59528
Checksum: AE513312A999B763
Sequence:

MKKISLKTLR KSFNLNKSKE ETDFMVVQQP SLASDFGKDD SLFGSCYGKD MASCDINGED 
EKGGKNRSKS ESLMGTLKRR LSAKQKSKGK AGTPSGSSAD EDTFSSSSAP IVFKDVRAQR 
PIRSTSLRSH HYSPAPWPLR PTNSEETCIK MEVRVKALVH SSSPSPALNG VRKDFHDLQS 
ETTCQEQANS LKSSASHNGD LHLHLDEHVP VVIGLMPQDY IQYTVPLDEG MYPLEGSRSY 
CLDSSSPMEV SAVPPQVGGR AFPEDESQVD QDLVVAPEIF VDQSVNGLLI GTTGVMLQSP 
RAGHDDVPPL SPLLPPMQNN QIQRNFSGLT GTEAHVAESM RCHLNFDPNS APGVARVYDS 
VQSSGPMVVT SLTEELKKLA KQGWYWGPIT RWEAEGKLAN VPDGSFLVRD SSDDRYLLSL 
SFRSHGKTLH TRIEHSNGRF SFYEQPDVEG HTSIVDLIEH SIRDSENGAF CYSRSRLPGS 
ATYPVRLTNP VSRFMQVRSL QYLCRFVIRQ YTRIDLIQKL PLPNKMKDYL QEKHY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: SOCS6

Associated with

Other Information

Cloning and characterization of novel CIS family genes. PubMed ID: 9344848

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Signal transduction via the stem cell factor receptor/c-Kit. PubMed ID: 15526160

Structural basis for c-KIT inhibition by the suppressor of cytokine signaling 6 (SOCS6) ubiquitin ligase. PubMed ID: 21030588

Database document:

PubMed ID: 9344848

PubMed ID: 15489334

PubMed ID: 15526160

PubMed ID: 21030588