TRIP13 | ENSG00000071539 | NCBI 9319

Details for: TRIP13

Gene ID: 9319

Symbol: TRIP13

Ensembl ID: ENSG00000071539

Description: thyroid hormone receptor interactor 13

Associated with

Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Chromosome
(GO:0005694)
Double-strand break repair
(GO:0006302)
Female meiosis i
(GO:0007144)
Identical protein binding
(GO:0042802)
Male germ cell nucleus
(GO:0001673)
Male meiosis i
(GO:0007141)
Meiotic recombination checkpoint signaling
(GO:0051598)
Mitotic spindle assembly checkpoint signaling
(GO:0007094)
Nucleus
(GO:0005634)
Oocyte maturation
(GO:0001556)
Oogenesis
(GO:0048477)
Protein binding
(GO:0005515)
Reciprocal meiotic recombination
(GO:0007131)
Spermatid development
(GO:0007286)
Spermatogenesis
(GO:0007283)
Synaptonemal complex assembly
(GO:0007130)
Transcription by rna polymerase ii
(GO:0006366)
Transcription coregulator activity
(GO:0003712)

Other Information

Proteins

Pachytene checkpoint protein 2 homolog

Genular Protein ID: 3303581784

Symbol: PCH2_HUMAN

Name: Pachytene checkpoint protein 2 homolog

UniProtKB Accession Codes:

Q15645 C9K0T3 D3DTC0 O15324

Database IDs:

Citations:

PubMed ID: 9223484

Title: Two classes of human papillomavirus type 16 E1 mutants suggest pleiotropic conformational constraints affecting E1 multimerization, E2 interaction, and interaction with cellular proteins.

PubMed ID: 9223484

DOI: 10.1128/jvi.71.8.5942-5951.1997

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7776974

Title: Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.

PubMed ID: 7776974

DOI: 10.1210/mend.9.2.7776974

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 28553959

Title: Biallelic TRIP13 mutations predispose to Wilms tumor and chromosome missegregation.

PubMed ID: 28553959

DOI: 10.1038/ng.3883

PubMed ID: 32473092

Title: Bi-allelic missense pathogenic variants in TRIP13 cause female infertility characterized by oocyte maturation arrest.

PubMed ID: 32473092

DOI: 10.1016/j.ajhg.2020.05.001

Sequence Information:

Length: 432
Mass: 48551
Checksum: DFB0B37462D1D581
Sequence:

MDEAVGDLKQ ALPCVAESPT VHVEVHQRGS STAKKEDINL SVRKLLNRHN IVFGDYTWTE 
FDEPFLTRNV QSVSIIDTEL KVKDSQPIDL SACTVALHIF QLNEDGPSSE NLEEETENII 
AANHWVLPAA EFHGLWDSLV YDVEVKSHLL DYVMTTLLFS DKNVNSNLIT WNRVVLLHGP 
PGTGKTSLCK ALAQKLTIRL SSRYRYGQLI EINSHSLFSK WFSESGKLVT KMFQKIQDLI 
DDKDALVFVL IDEVESLTAA RNACRAGTEP SDAIRVVNAV LTQIDQIKRH SNVVILTTSN 
ITEKIDVAFV DRADIKQYIG PPSAAAIFKI YLSCLEELMK CQIIYPRQQL LTLRELEMIG 
FIENNVSKLS LLLNDISRKS EGLSGRVLRK LPFLAHALYV QAPTVTIEGF LQALSLAVDK 
QFEERKKLAA YI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: TRIP13

Associated with

Other Information

Two classes of human papillomavirus type 16 E1 mutants suggest pleiotropic conformational constraints affecting E1 multimerization, E2 interaction, and interaction with cellular proteins. PubMed ID: 9223484

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor. PubMed ID: 7776974

Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. PubMed ID: 15592455

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. PubMed ID: 17081983

Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. PubMed ID: 18691976

Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. PubMed ID: 19413330

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

Initial characterization of the human central proteome. PubMed ID: 21269460

Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features. PubMed ID: 22223895

Biallelic TRIP13 mutations predispose to Wilms tumor and chromosome missegregation. PubMed ID: 28553959

Bi-allelic missense pathogenic variants in TRIP13 cause female infertility characterized by oocyte maturation arrest. PubMed ID: 32473092