Details for: CD22

Gene ID: 933

Symbol: CD22

Ensembl ID: ENSG00000012124

Description: CD22 molecule

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 32.4664
    Cell Significance Index: -5.0500
  • Cell Name: centroblast (CL0009112)
    Fold Change: 20.8396
    Cell Significance Index: 48.6200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 17.7414
    Cell Significance Index: -4.5000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 15.6551
    Cell Significance Index: -6.3600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 12.1155
    Cell Significance Index: -5.7200
  • Cell Name: centrocyte (CL0009111)
    Fold Change: 4.9185
    Cell Significance Index: 15.1700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 4.1040
    Cell Significance Index: -5.0600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 3.8827
    Cell Significance Index: 457.8900
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 3.2782
    Cell Significance Index: 14.6600
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 2.9966
    Cell Significance Index: 25.4700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 2.3077
    Cell Significance Index: 61.8400
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 1.3954
    Cell Significance Index: 17.8700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 1.3152
    Cell Significance Index: -5.1900
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 0.9570
    Cell Significance Index: 5.7800
  • Cell Name: theca cell (CL0000503)
    Fold Change: 0.8817
    Cell Significance Index: 5.1800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.6400
    Cell Significance Index: 16.8300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.6178
    Cell Significance Index: 39.8600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.5306
    Cell Significance Index: 11.5000
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 0.4693
    Cell Significance Index: 2.2800
  • Cell Name: follicular B cell (CL0000843)
    Fold Change: 0.4578
    Cell Significance Index: 2.2900
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.3398
    Cell Significance Index: 7.8500
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 0.2987
    Cell Significance Index: 1.4900
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.2928
    Cell Significance Index: 4.5300
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: 0.2641
    Cell Significance Index: 2.3200
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 0.2196
    Cell Significance Index: 3.0800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2107
    Cell Significance Index: 34.2800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1712
    Cell Significance Index: 10.2800
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 0.1324
    Cell Significance Index: 1.4200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.0718
    Cell Significance Index: 44.8200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0315
    Cell Significance Index: 17.1800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0272
    Cell Significance Index: 2.7000
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 0.0237
    Cell Significance Index: 0.2700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.0219
    Cell Significance Index: 2.5000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0218
    Cell Significance Index: 0.4700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0139
    Cell Significance Index: 2.7800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0057
    Cell Significance Index: 2.0500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.0052
    Cell Significance Index: 0.5700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0050
    Cell Significance Index: 1.0000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0013
    Cell Significance Index: -2.4000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0014
    Cell Significance Index: -2.5500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0023
    Cell Significance Index: -3.5600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0024
    Cell Significance Index: -1.8100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0025
    Cell Significance Index: -1.3900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0027
    Cell Significance Index: -3.6300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0065
    Cell Significance Index: -4.9300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0082
    Cell Significance Index: -5.2300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0085
    Cell Significance Index: -6.2100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0087
    Cell Significance Index: -1.5700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: -0.0094
    Cell Significance Index: -1.7800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0096
    Cell Significance Index: -1.3200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0110
    Cell Significance Index: -4.9900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0145
    Cell Significance Index: -4.1800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0152
    Cell Significance Index: -3.2100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0161
    Cell Significance Index: -2.7500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0254
    Cell Significance Index: -2.9100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0263
    Cell Significance Index: -3.8200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0278
    Cell Significance Index: -0.8000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0353
    Cell Significance Index: -4.5300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0367
    Cell Significance Index: -2.5400
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0367
    Cell Significance Index: -0.5300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0403
    Cell Significance Index: -1.2900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0448
    Cell Significance Index: -5.5100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0454
    Cell Significance Index: -0.8400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0456
    Cell Significance Index: -4.6600
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0458
    Cell Significance Index: -0.6900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0475
    Cell Significance Index: -5.5400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0478
    Cell Significance Index: -6.1700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0484
    Cell Significance Index: -5.0400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0524
    Cell Significance Index: -1.8200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0541
    Cell Significance Index: -3.6400
  • Cell Name: B-1b B cell (CL0000821)
    Fold Change: -0.0558
    Cell Significance Index: -0.2800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0575
    Cell Significance Index: -1.4700
  • Cell Name: memory B cell (CL0000787)
    Fold Change: -0.0620
    Cell Significance Index: -0.6600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0622
    Cell Significance Index: -1.6000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0632
    Cell Significance Index: -1.3100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0681
    Cell Significance Index: -3.0900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0714
    Cell Significance Index: -1.9100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0722
    Cell Significance Index: -5.5400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0736
    Cell Significance Index: -4.1300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0739
    Cell Significance Index: -5.5100
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0830
    Cell Significance Index: -3.6100
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0948
    Cell Significance Index: -2.7900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0949
    Cell Significance Index: -5.8300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0950
    Cell Significance Index: -1.5900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0952
    Cell Significance Index: -2.6600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0957
    Cell Significance Index: -1.6400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0983
    Cell Significance Index: -4.6200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0993
    Cell Significance Index: -5.1600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1092
    Cell Significance Index: -4.8300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1098
    Cell Significance Index: -2.7500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1110
    Cell Significance Index: -5.8300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1148
    Cell Significance Index: -4.0200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1192
    Cell Significance Index: -6.2100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1215
    Cell Significance Index: -6.1400
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1256
    Cell Significance Index: -4.6100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1270
    Cell Significance Index: -5.9200
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.1278
    Cell Significance Index: -1.6200
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.1295
    Cell Significance Index: -5.3000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1315
    Cell Significance Index: -4.3100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1360
    Cell Significance Index: -4.3300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** CD22 is a member of the C-type lectin family and is expressed on the surface of mature B cells, with the exception of plasma cells. Its primary function is to regulate B cell receptor signaling, which is essential for the activation and proliferation of B cells in response to antigens. CD22 is also involved in the negative regulation of B cell receptor signaling, which prevents excessive activation and autoimmunity. The molecule has two main domains: the extracellular domain, which binds to sialic acid and other carbohydrates, and the intracellular domain, which interacts with cytoplasmic signaling molecules. **Pathways and Functions:** CD22 is involved in several key signaling pathways that regulate B cell function: 1. **Antigen-activated BCR signaling:** CD22 binds to sialic acid and other carbohydrates on the surface of antigens, leading to the activation of the BCR and the generation of second messengers, such as inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG). 2. **Negative regulation of BCR signaling:** CD22 interacts with cytoplasmic signaling molecules, such as protein phosphatase 2A (PP2A), to modulate the activity of the BCR signaling pathway, preventing excessive activation and autoimmunity. 3. **Regulation of B cell proliferation:** CD22 influences the proliferation of B cells by modulating the activity of signaling pathways that control cell cycle progression. 4. **Immune response regulation:** CD22 plays a role in regulating the immune response by modulating the activity of B cells and other immune cells, such as T cells and dendritic cells. **Clinical Significance:** CD22 has been implicated in several immunological disorders, including: 1. **Autoimmune diseases:** CD22 dysfunction has been linked to autoimmune diseases, such as rheumatoid arthritis and lupus, where it contributes to the excessive activation and proliferation of autoreactive B cells. 2. **Cancer:** CD22 has been identified as a target for antibody-based therapies in cancer, such as chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma (NHL). 3. **Infectious diseases:** CD22 may play a role in the regulation of the immune response to infections, such as influenza and pneumococcal disease. 4. **Immunodeficiency disorders:** CD22 deficiency has been associated with immunodeficiency disorders, such as X-linked lymphoproliferative disease (XLP). In conclusion, CD22 is a critical regulator of B cell function and immune response, and its dysfunction has been implicated in several immunological disorders. Further research is needed to fully understand the mechanisms of CD22 function and its role in the regulation of the immune system.

Genular Protein ID: 366550295

Symbol: CD22_HUMAN

Name: B-lymphocyte cell adhesion molecule

UniProtKB Accession Codes:

P20273 F5GYU4 F5H7U3 O95699 O95701 O95702 O95703 Q01665 Q32M46 Q92872 Q92873 Q9UQA6 Q9UQA7 Q9UQA8 Q9UQA9 Q9UQB0 Q9Y2A6

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CDD 3 CTD 1 ChEBI 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 3 DrugCentral 1 ELM 1 EMBL 17 Ensembl 6 ExpressionAtlas 1 GO 23 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 RNAct 1 Reactome 3 RefSeq 5 SASBDB 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniLectin 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1691828

Title: The B-cell antigen CD22 mediates monocyte and erythrocyte adhesion.

PubMed ID: 1691828

DOI: 10.1038/345074a0

PubMed ID: 1985119

Title: cDNA cloning of the B cell membrane protein CD22: a mediator of B-B cell interactions.

PubMed ID: 1985119

DOI: 10.1084/jem.173.1.137

PubMed ID: 8496602

Title: Genomic structure and chromosomal mapping of the human CD22 gene.

PubMed ID: 8496602

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10079291

Title: Identification of the gene variations in human CD22.

PubMed ID: 10079291

DOI: 10.1007/s002510050494

PubMed ID: 8463235

Title: Natural ligands of the B cell adhesion molecule CD22 beta carry N-linked oligosaccharides with alpha-2,6-linked sialic acids that are required for recognition.

PubMed ID: 8463235

DOI: 10.1016/s0021-9258(18)53140-9

PubMed ID: 7618087

Title: A role in B cell activation for CD22 and the protein tyrosine phosphatase SHP.

PubMed ID: 7618087

DOI: 10.1126/science.7618087

PubMed ID: 8647200

Title: Involvement of p72syk kinase, p53/56lyn kinase and phosphatidyl inositol-3 kinase in signal transduction via the human B lymphocyte antigen CD22.

PubMed ID: 8647200

DOI: 10.1002/eji.1830260610

PubMed ID: 8627166

Title: CD22 associates with protein tyrosine phosphatase 1C, Syk, and phospholipase C-gamma(1) upon B cell activation.

PubMed ID: 8627166

DOI: 10.1084/jem.183.2.547

PubMed ID: 9143697

Title: CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling.

PubMed ID: 9143697

DOI: 10.1146/annurev.immunol.15.1.481

PubMed ID: 20172905

Title: In situ trans ligands of CD22 identified by glycan-protein photocross-linking-enabled proteomics.

PubMed ID: 20172905

DOI: 10.1074/mcp.m900461-mcp200

PubMed ID: 20516366

Title: IVIg modulates BCR signaling through CD22 and promotes apoptosis in mature human B lymphocytes.

PubMed ID: 20516366

DOI: 10.1182/blood-2009-12-261461

PubMed ID: 34330755

Title: CD22 Controls Germinal Center B Cell Receptor Signaling, Which Influences Plasma Cell and Memory B Cell Output.

PubMed ID: 34330755

DOI: 10.4049/jimmunol.2100132

PubMed ID: 34273351

Title: Structural details of monoclonal antibody m971 recognition of the membrane-proximal domain of CD22.

PubMed ID: 34273351

DOI: 10.1016/j.jbc.2021.100966

Sequence Information:

  • Length: 847
  • Mass: 95348
  • Checksum: 38EB0BE4220ACA2D
  • Sequence:
    • MHLLGPWLLL LVLEYLAFSD SSKWVFEHPE TLYAWEGACV WIPCTYRALD GDLESFILFH 
NPEYNKNTSK FDGTRLYEST KDGKVPSEQK RVQFLGDKNK NCTLSIHPVH LNDSGQLGLR 
MESKTEKWME RIHLNVSERP FPPHIQLPPE IQESQEVTLT CLLNFSCYGY PIQLQWLLEG 
VPMRQAAVTS TSLTIKSVFT RSELKFSPQW SHHGKIVTCQ LQDADGKFLS NDTVQLNVKH 
TPKLEIKVTP SDAIVREGDS VTMTCEVSSS NPEYTTVSWL KDGTSLKKQN TFTLNLREVT 
KDQSGKYCCQ VSNDVGPGRS EEVFLQVQYA PEPSTVQILH SPAVEGSQVE FLCMSLANPL 
PTNYTWYHNG KEMQGRTEEK VHIPKILPWH AGTYSCVAEN ILGTGQRGPG AELDVQYPPK 
KVTTVIQNPM PIREGDTVTL SCNYNSSNPS VTRYEWKPHG AWEEPSLGVL KIQNVGWDNT 
TIACAACNSW CSWASPVALN VQYAPRDVRV RKIKPLSEIH SGNSVSLQCD FSSSHPKEVQ 
FFWEKNGRLL GKESQLNFDS ISPEDAGSYS CWVNNSIGQT ASKAWTLEVL YAPRRLRVSM 
SPGDQVMEGK SATLTCESDA NPPVSHYTWF DWNNQSLPYH SQKLRLEPVK VQHSGAYWCQ 
GTNSVGKGRS PLSTLTVYYS PETIGRRVAV GLGSCLAILI LAICGLKLQR RWKRTQSQQG 
LQENSSGQSF FVRNKKVRRA PLSEGPHSLG CYNPMMEDGI SYTTLRFPEM NIPRTGDAES 
SEMQRPPPDC DDTVTYSALH KRQVGDYENV IPDFPEDEGI HYSELIQFGV GERPQAQENV 
DYVILKH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.