Details for: CD163

Gene ID: 9332

Symbol: CD163

Ensembl ID: ENSG00000177575

Description: CD163 molecule

Associated with

Other Information

Genular Protein ID: 4255777138

Symbol: C163A_HUMAN

Name: Scavenger receptor cysteine-rich type 1 protein M130

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8370408

Title: A new macrophage differentiation antigen which is a member of the scavenger receptor superfamily.

PubMed ID: 8370408

DOI: 10.1002/eji.1830230940

PubMed ID: 10403791

Title: Genomic organization and chromosomal localization of the human CD163 (M130) gene: a member of the scavenger receptor cysteine-rich superfamily.

PubMed ID: 10403791

DOI: 10.1006/bbrc.1999.0866

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10066432

Title: Shedding of CD163, a novel regulatory mechanism for a member of the scavenger receptor cysteine-rich family.

PubMed ID: 10066432

DOI: 10.1006/bbrc.1999.0294

PubMed ID: 10577520

Title: Regulation of CD 163 on human macrophages: cross-linking of CD163 induces signaling and activation.

PubMed ID: 10577520

DOI: 10.1002/jlb.66.5.858

PubMed ID: 10648003

Title: Regulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro- and antiinflammatory stimuli.

PubMed ID: 10648003

DOI: 10.1002/jlb.67.1.97

PubMed ID: 11298324

Title: Interaction of CD163 with the regulatory subunit of casein kinase II (CKII) and dependence of CD163 signaling on CKII and protein kinase C.

PubMed ID: 11298324

DOI: 10.1002/1521-4141(200104)31:4<999::aid-immu999>3.0.co;2-r

PubMed ID: 11196644

Title: Identification of the haemoglobin scavenger receptor.

PubMed ID: 11196644

DOI: 10.1038/35051594

PubMed ID: 12296867

Title: Elevated levels of soluble CD163 in sera and fluids from rheumatoid arthritis patients and inhibition of the shedding of CD163 by TIMP-3.

PubMed ID: 12296867

DOI: 10.1046/j.1365-2249.2002.01963.x

PubMed ID: 12208511

Title: Only the soluble form of the scavenger receptor CD163 acts inhibitory on phorbol ester-activated T-lymphocytes, whereas membrane-bound protein has no effect.

PubMed ID: 12208511

DOI: 10.1016/s0014-5793(02)03142-3

PubMed ID: 12377940

Title: Endotoxin induces rapid metalloproteinase-mediated shedding followed by up-regulation of the monocyte hemoglobin scavenger receptor CD163.

PubMed ID: 12377940

PubMed ID: 15478309

Title: CD163: a regulated hemoglobin scavenger receptor with a role in the anti-inflammatory response.

PubMed ID: 15478309

DOI: 10.1080/07853890410033171

PubMed ID: 15448162

Title: Molecular characterization of the haptoglobin.hemoglobin receptor CD163. Ligand binding properties of the scavenger receptor cysteine-rich domain region.

PubMed ID: 15448162

DOI: 10.1074/jbc.m409629200

PubMed ID: 15075364

Title: Cross-linking of FcgammaR triggers shedding of the hemoglobin-haptoglobin scavenger receptor CD163.

PubMed ID: 15075364

DOI: 10.1189/jlb.1003523

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 16434690

Title: The macrophage scavenger receptor CD163: endocytic properties of cytoplasmic tail variants.

PubMed ID: 16434690

DOI: 10.1189/jlb.1005602

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19139490

Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.

PubMed ID: 19139490

DOI: 10.1074/mcp.m800504-mcp200

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 1156
  • Mass: 125451
  • Checksum: 57B49F76DA6C96EB
  • Sequence:
  • MSKLRMVLLE DSGSADFRRH FVNLSPFTIT VVLLLSACFV TSSLGGTDKE LRLVDGENKC 
    SGRVEVKVQE EWGTVCNNGW SMEAVSVICN QLGCPTAIKA PGWANSSAGS GRIWMDHVSC 
    RGNESALWDC KHDGWGKHSN CTHQQDAGVT CSDGSNLEMR LTRGGNMCSG RIEIKFQGRW 
    GTVCDDNFNI DHASVICRQL ECGSAVSFSG SSNFGEGSGP IWFDDLICNG NESALWNCKH 
    QGWGKHNCDH AEDAGVICSK GADLSLRLVD GVTECSGRLE VRFQGEWGTI CDDGWDSYDA 
    AVACKQLGCP TAVTAIGRVN ASKGFGHIWL DSVSCQGHEP AIWQCKHHEW GKHYCNHNED 
    AGVTCSDGSD LELRLRGGGS RCAGTVEVEI QRLLGKVCDR GWGLKEADVV CRQLGCGSAL 
    KTSYQVYSKI QATNTWLFLS SCNGNETSLW DCKNWQWGGL TCDHYEEAKI TCSAHREPRL 
    VGGDIPCSGR VEVKHGDTWG SICDSDFSLE AASVLCRELQ CGTVVSILGG AHFGEGNGQI 
    WAEEFQCEGH ESHLSLCPVA PRPEGTCSHS RDVGVVCSRY TEIRLVNGKT PCEGRVELKT 
    LGAWGSLCNS HWDIEDAHVL CQQLKCGVAL STPGGARFGK GNGQIWRHMF HCTGTEQHMG 
    DCPVTALGAS LCPSEQVASV ICSGNQSQTL SSCNSSSLGP TRPTIPEESA VACIESGQLR 
    LVNGGGRCAG RVEIYHEGSW GTICDDSWDL SDAHVVCRQL GCGEAINATG SAHFGEGTGP 
    IWLDEMKCNG KESRIWQCHS HGWGQQNCRH KEDAGVICSE FMSLRLTSEA SREACAGRLE 
    VFYNGAWGTV GKSSMSETTV GVVCRQLGCA DKGKINPASL DKAMSIPMWV DNVQCPKGPD 
    TLWQCPSSPW EKRLASPSEE TWITCDNKIR LQEGPTSCSG RVEIWHGGSW GTVCDDSWDL 
    DDAQVVCQQL GCGPALKAFK EAEFGQGTGP IWLNEVKCKG NESSLWDCPA RRWGHSECGH 
    KEDAAVNCTD ISVQKTPQKA TTGRSSRQSS FIAVGILGVV LLAIFVALFF LTKKRRQRQR 
    LAVSSRGENL VHQIQYREMN SCLNADDLDL MNSSENSHES ADFSAAELIS VSKFLPISGM 
    EKEAILSHTE KENGNL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.