B4GALT5 | ENSG00000158470 | NCBI 9334

Details for: B4GALT5

Gene ID: 9334

Symbol: B4GALT5

Ensembl ID: ENSG00000158470

Description: beta-1,4-galactosyltransferase 5

Associated with

Asparagine n-linked glycosylation
(R-HSA-446203)
Glycosaminoglycan metabolism
(R-HSA-1630316)
Glycosphingolipid biosynthesis
(R-HSA-9840309)
Glycosphingolipid metabolism
(R-HSA-1660662)
Keratan sulfate/keratin metabolism
(R-HSA-1638074)
Keratan sulfate biosynthesis
(R-HSA-2022854)
Metabolism
(R-HSA-1430728)
Metabolism of carbohydrates
(R-HSA-71387)
Metabolism of lipids
(R-HSA-556833)
Metabolism of proteins
(R-HSA-392499)
N-glycan antennae elongation
(R-HSA-975577)
N-glycan antennae elongation in the medial/trans-golgi
(R-HSA-975576)
O-linked glycosylation
(R-HSA-5173105)
O-linked glycosylation of mucins
(R-HSA-913709)
Post-translational protein modification
(R-HSA-597592)
Sphingolipid metabolism
(R-HSA-428157)
Transport to the golgi and subsequent modification
(R-HSA-948021)
Carbohydrate metabolic process
(GO:0005975)
Central nervous system myelination
(GO:0022010)
Central nervous system neuron axonogenesis
(GO:0021955)
Galactosyltransferase activity
(GO:0008378)
Ganglioside biosynthetic process via lactosylceramide
(GO:0010706)
Glycoprotein biosynthetic process
(GO:0009101)
Glycosylation
(GO:0070085)
Golgi apparatus
(GO:0005794)
Golgi cisterna membrane
(GO:0032580)
Golgi membrane
(GO:0000139)
Metal ion binding
(GO:0046872)
N-acetyllactosamine synthase activity
(GO:0003945)
Neuron maturation
(GO:0042551)
O-glycan processing
(GO:0016266)
Poly-n-acetyllactosamine biosynthetic process
(GO:0030311)
Positive regulation of embryonic development
(GO:0040019)
Protein glycosylation
(GO:0006486)
Regulation of protein stability
(GO:0031647)
Udp-galactose:glucosylceramide beta-1,4-galactosyltransferase activity
(GO:0008489)

Other Information

Proteins

Beta-1,4-galactosyltransferase 5

Genular Protein ID: 3680851238

Symbol: B4GT5_HUMAN

Name: Beta-1,4-galactosyltransferase 5

UniProtKB Accession Codes:

O43286 E1P625 Q2M394 Q9UJQ8 U6C5D7

Database IDs:

Citations:

PubMed ID: 9435216

Title: Molecular cloning of a human cDNA encoding beta-1,4-galactosyltransferase with 37% identity to mammalian UDP-Gal:GlcNAc beta-1,4-galactosyltransferase.

PubMed ID: 9435216

DOI: 10.1073/pnas.95.2.472

PubMed ID: 9597550

Title: The expanding beta 4-galactosyltransferase gene family: messages from the databanks.

PubMed ID: 9597550

DOI: 10.1093/glycob/8.5.517

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 24498430

Title: Establishment of HeLa cell mutants deficient in sphingolipid-related genes using TALENs.

PubMed ID: 24498430

DOI: 10.1371/journal.pone.0088124

PubMed ID: 10580128

Title: Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions.

PubMed ID: 10580128

DOI: 10.1016/s0304-4165(99)00168-3

PubMed ID: 29415997

Title: Downregulation of beta1,4-galactosyltransferase 5 improves insulin resistance by promoting adipocyte commitment and reducing inflammation.

PubMed ID: 29415997

DOI: 10.1038/s41419-017-0239-5

Sequence Information:

Length: 388
Mass: 45119
Checksum: A71F3F8999B6E13A
Sequence:

MRARRGLLRL PRRSLLAALF FFSLSSSLLY FVYVAPGIVN TYLFMMQAQG ILIRDNVRTI 
GAQVYEQVLR SAYAKRNSSV NDSDYPLDLN HSETFLQTTT FLPEDFTYFA NHTCPERLPS 
MKGPIDINMS EIGMDYIHEL FSKDPTIKLG GHWKPSDCMP RWKVAILIPF RNRHEHLPVL 
FRHLLPMLQR QRLQFAFYVV EQVGTQPFNR AMLFNVGFQE AMKDLDWDCL IFHDVDHIPE 
SDRNYYGCGQ MPRHFATKLD KYMYLLPYTE FFGGVSGLTV EQFRKINGFP NAFWGWGGED 
DDLWNRVQNA GYSVSRPEGD TGKYKSIPHH HRGEVQFLGR YALLRKSKER QGLDGLNNLN 
YFANITYDAL YKNITVNLTP ELAQVNEY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: B4GALT5

Associated with

Other Information

Molecular cloning of a human cDNA encoding beta-1,4-galactosyltransferase with 37% identity to mammalian UDP-Gal:GlcNAc beta-1,4-galactosyltransferase. PubMed ID: 9435216

The expanding beta 4-galactosyltransferase gene family: messages from the databanks. PubMed ID: 9597550

The DNA sequence and comparative analysis of human chromosome 20. PubMed ID: 11780052

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Establishment of HeLa cell mutants deficient in sphingolipid-related genes using TALENs. PubMed ID: 24498430

Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions. PubMed ID: 10580128

Downregulation of beta1,4-galactosyltransferase 5 improves insulin resistance by promoting adipocyte commitment and reducing inflammation. PubMed ID: 29415997