Details for: NHERF2

Gene ID: 9351

Symbol: NHERF2

Ensembl ID: ENSG00000065054

Description: NHERF family PDZ scaffold protein 2

Associated with

Other Information

Genular Protein ID: 808335463

Symbol: NHRF2_HUMAN

Name: NHE3 kinase A regulatory protein E3KARP

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9054412

Title: The human testis determining factor SRY binds a nuclear factor containing PDZ protein interaction domains.

PubMed ID: 9054412

DOI: 10.1074/jbc.272.11.7167

PubMed ID: 9314537

Title: Identification of EBP50: a PDZ-containing phosphoprotein that associates with members of the ezrin-radixin-moesin family.

PubMed ID: 9314537

DOI: 10.1083/jcb.139.1.169

PubMed ID: 9096337

Title: cAMP-mediated inhibition of the epithelial brush border Na+/H+ exchanger, NHE3, requires an associated regulatory protein.

PubMed ID: 9096337

DOI: 10.1073/pnas.94.7.3010

PubMed ID: 9831664

Title: Genomic structure and sequence of a human homologue (NTHL1/NTH1) of Escherichia coli endonuclease III with those of the adjacent parts of TSC2 and SLC9A3R2 genes.

PubMed ID: 9831664

DOI: 10.1016/s0378-1119(98)00485-5

PubMed ID: 9671706

Title: A C-terminal motif found in the beta2-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na+/H+ exchanger regulatory factor family of PDZ proteins.

PubMed ID: 9671706

DOI: 10.1073/pnas.95.15.8496

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10455146

Title: cAMP-induced phosphorylation and inhibition of Na(+)/H(+) exchanger 3 (NHE3) are dependent on the presence but not the phosphorylation of NHE regulatory factor.

PubMed ID: 10455146

DOI: 10.1074/jbc.274.35.24753

PubMed ID: 12444019

Title: Isoforms of SLC26A6 mediate anion transport and have functional PDZ interaction domains.

PubMed ID: 12444019

DOI: 10.1152/ajpcell.00270.2002

PubMed ID: 14623317

Title: Molecular requirements for the regulation of the renal outer medullary K(+) channel ROMK1 by the serum- and glucocorticoid-inducible kinase SGK1.

PubMed ID: 14623317

DOI: 10.1016/j.bbrc.2003.10.037

PubMed ID: 15143197

Title: NHERF2 specifically interacts with LPA2 receptor and defines the specificity and efficiency of receptor-mediated phospholipase C-beta3 activation.

PubMed ID: 15143197

DOI: 10.1128/mcb.24.11.5069-5079.2004

PubMed ID: 15642748

Title: Gp135/podocalyxin and NHERF-2 participate in the formation of a preapical domain during polarization of MDCK cells.

PubMed ID: 15642748

DOI: 10.1083/jcb.200407072

PubMed ID: 18829453

Title: IRBIT, inositol 1,4,5-triphosphate (IP3) receptor-binding protein released with IP3, binds Na+/H+ exchanger NHE3 and activates NHE3 activity in response to calcium.

PubMed ID: 18829453

DOI: 10.1074/jbc.m805534200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19555689

Title: MCC, a new interacting protein for Scrib, is required for cell migration in epithelial cells.

PubMed ID: 19555689

DOI: 10.1016/j.febslet.2009.06.034

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 16615918

Title: Structural basis for NHERF recognition by ERM proteins.

PubMed ID: 16615918

DOI: 10.1016/j.str.2006.01.015

Sequence Information:

  • Length: 337
  • Mass: 37414
  • Checksum: 4F5D341590D22ED7
  • Sequence:
  • MAAPEPLRPR LCRLVRGEQG YGFHLHGEKG RRGQFIRRVE PGSPAEAAAL RAGDRLVEVN 
    GVNVEGETHH QVVQRIKAVE GQTRLLVVDQ ETDEELRRRQ LTCTEEMAQR GLPPAHDPWE 
    PKPDWAHTGS HSSEAGKKDV SGPLRELRPR LCHLRKGPQG YGFNLHSDKS RPGQYIRSVD 
    PGSPAARSGL RAQDRLIEVN GQNVEGLRHA EVVASIKARE DEARLLVVDP ETDEHFKRLR 
    VTPTEEHVEG PLPSPVTNGT SPAQLNGGSA CSSRSDLPGS DKDTEDGSAW KQDPFQESGL 
    HLSPTAAEAK EKARAMRVNK RAPQMDWNRK REIFSNF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.