Details for: PLAA

Gene ID: 9373

Symbol: PLAA

Ensembl ID: ENSG00000137055

Description: phospholipase A2 activating protein

Associated with

Other Information

Genular Protein ID: 97937506

Symbol: PLAP_HUMAN

Name: Phospholipase A-2-activating protein

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10644453

Title: Chromosomal localization of phospholipase A2 activating protein, an ets2 target gene, to 9p21.

PubMed ID: 10644453

DOI: 10.1006/geno.1999.5999

PubMed ID: 10571045

Title: Cloning of the human phospholipase A2 activating protein (hPLAP) gene on the chromosome 9p21 melanoma deleted region.

PubMed ID: 10571045

DOI: 10.1016/s0378-1119(99)00354-6

PubMed ID: 9931468

Title: Molecular characterization of cDNA for phospholipase A2-activating protein.

PubMed ID: 9931468

DOI: 10.1016/s0167-4781(98)00249-8

PubMed ID: 18291623

Title: Alteration in the activation state of new inflammation-associated targets by phospholipase A2-activating protein (PLAA).

PubMed ID: 18291623

DOI: 10.1016/j.cellsig.2008.01.004

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 27753622

Title: VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy.

PubMed ID: 27753622

DOI: 10.15252/embj.201695148

PubMed ID: 19423704

Title: Structural basis for ubiquitin recognition by a novel domain from human phospholipase A2-activating protein.

PubMed ID: 19423704

DOI: 10.1074/jbc.m109.009126

PubMed ID: 19887378

Title: Structure and function of the PLAA/Ufd3-p97/Cdc48 complex.

PubMed ID: 19887378

DOI: 10.1074/jbc.m109.044685

PubMed ID: 28413018

Title: PLAA mutations cause a lethal infantile epileptic encephalopathy by disrupting ubiquitin-mediated endolysosomal degradation of synaptic proteins.

PubMed ID: 28413018

DOI: 10.1016/j.ajhg.2017.03.008

PubMed ID: 28007986

Title: Phospholipase A2-activating protein is associated with a novel form of leukoencephalopathy.

PubMed ID: 28007986

DOI: 10.1093/brain/aww295

Sequence Information:

  • Length: 795
  • Mass: 87157
  • Checksum: D6E7330AC9891637
  • Sequence:
  • MTSGATRYRL SCSLRGHELD VRGLVCCAYP PGAFVSVSRD RTTRLWAPDS PNRSFTEMHC 
    MSGHSNFVSC VCIIPSSDIY PHGLIATGGN DHNICIFSLD SPMPLYILKG HKNTVCSLSS 
    GKFGTLLSGS WDTTAKVWLN DKCMMTLQGH TAAVWAVKIL PEQGLMLTGS ADKTVKLWKA 
    GRCERTFSGH EDCVRGLAIL SETEFLSCAN DASIRRWQIT GECLEVYYGH TNYIYSISVF 
    PNCRDFVTTA EDRSLRIWKH GECAQTIRLP AQSIWCCCVL DNGDIVVGAS DGIIRVFTES 
    EDRTASAEEI KAFEKELSHA TIDSKTGDLG DINAEQLPGR EHLNEPGTRE GQTRLIRDGE 
    KVEAYQWSVS EGRWIKIGDV VGSSGANQQT SGKVLYEGKE FDYVFSIDVN EGGPSYKLPY 
    NTSDDPWLTA YNFLQKNDLN PMFLDQVAKF IIDNTKGQML GLGNPSFSDP FTGGGRYVPG 
    SSGSSNTLPT ADPFTGAGRY VPGSASMGTT MAGVDPFTGN SAYRSAASKT MNIYFPKKEA 
    VTFDQANPTQ ILGKLKELNG TAPEEKKLTE DDLILLEKIL SLICNSSSEK PTVQQLQILW 
    KAINCPEDIV FPALDILRLS IKHPSVNENF CNEKEGAQFS SHLINLLNPK GKPANQLLAL 
    RTFCNCFVGQ AGQKLMMSQR ESLMSHAIEL KSGSNKNIHI ALATLALNYS VCFHKDHNIE 
    GKAQCLSLIS TILEVVQDLE ATFRLLVALG TLISDDSNAV QLAKSLGVDS QIKKYSSVSE 
    PAKVSECCRF ILNLL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.