LIPG | ENSG00000101670 | NCBI 9388

Details for: LIPG

Gene ID: 9388

Symbol: LIPG

Ensembl ID: ENSG00000101670

Description: lipase G, endothelial type

Associated with

Hdl remodeling
(R-HSA-8964058)
Plasma lipoprotein assembly, remodeling, and clearance
(R-HSA-174824)
Plasma lipoprotein remodeling
(R-HSA-8963899)
Transport of small molecules
(R-HSA-382551)
1-acyl-2-lysophosphatidylserine acylhydrolase activity
(GO:0052740)
Cell surface
(GO:0009986)
Cholesterol homeostasis
(GO:0042632)
Early endosome
(GO:0005769)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Fatty acid biosynthetic process
(GO:0006633)
Golgi apparatus
(GO:0005794)
Heparin binding
(GO:0008201)
High-density lipoprotein particle remodeling
(GO:0034375)
Lipid metabolic process
(GO:0006629)
Lipoprotein lipase activity
(GO:0004465)
Phosphatidylserine 1-acylhydrolase activity
(GO:0052739)
Phospholipase a1 activity
(GO:0008970)
Phospholipase activity
(GO:0004620)
Phospholipid catabolic process
(GO:0009395)
Phospholipid homeostasis
(GO:0055091)
Positive regulation of cholesterol transport
(GO:0032376)
Positive regulation of high-density lipoprotein particle clearance
(GO:0010983)
Regulation of lipoprotein metabolic process
(GO:0050746)
Response to nutrient
(GO:0007584)
Reverse cholesterol transport
(GO:0043691)
Triglyceride catabolic process
(GO:0019433)
Triglyceride lipase activity
(GO:0004806)

Other Information

Proteins

Endothelial lipase
B4DTR8_HUMAN

Genular Protein ID: 3918319498

Symbol: LIPG_HUMAN

Name: Endothelial lipase

UniProtKB Accession Codes:

Q9Y5X9 B0LPG6 Q6P9C8 Q6UW82

Database IDs:

Citations:

PubMed ID: 10318835

Title: Cloning of a unique lipase from endothelial cells extends the lipase gene family.

PubMed ID: 10318835

DOI: 10.1074/jbc.274.20.14170

PubMed ID: 10192396

Title: A novel endothelial-derived lipase that modulates HDL metabolism.

PubMed ID: 10192396

DOI: 10.1038/7766

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12032167

Title: Characterization of the lipolytic activity of endothelial lipase.

PubMed ID: 12032167

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 19567873

Title: Identification of the active form of endothelial lipase, a homodimer in a head-to-tail conformation.

PubMed ID: 19567873

DOI: 10.1074/jbc.m109.037002

PubMed ID: 12966036

Title: Association of extreme blood lipid profile phenotypic variation with 11 reverse cholesterol transport genes and 10 non-genetic cardiovascular disease risk factors.

PubMed ID: 12966036

DOI: 10.1093/hmg/ddg314

Sequence Information:

Length: 500
Mass: 56795
Checksum: 96EC95125CD2A3FD
Sequence:

MSNSVPLLCF WSLCYCFAAG SPVPFGPEGR LEDKLHKPKA TQTEVKPSVR FNLRTSKDPE 
HEGCYLSVGH SQPLEDCSFN MTAKTFFIIH GWTMSGIFEN WLHKLVSALH TREKDANVVV 
VDWLPLAHQL YTDAVNNTRV VGHSIARMLD WLQEKDDFSL GNVHLIGYSL GAHVAGYAGN 
FVKGTVGRIT GLDPAGPMFE GADIHKRLSP DDADFVDVLH TYTRSFGLSI GIQMPVGHID 
IYPNGGDFQP GCGLNDVLGS IAYGTITEVV KCEHERAVHL FVDSLVNQDK PSFAFQCTDS 
NRFKKGICLS CRKNRCNSIG YNAKKMRNKR NSKMYLKTRA GMPFRVYHYQ MKIHVFSYKN 
MGEIEPTFYV TLYGTNADSQ TLPLEIVERI EQNATNTFLV YTEEDLGDLL KIQLTWEGAS 
QSWYNLWKEF RSYLSQPRNP GRELNIRRIR VKSGETQRKL TFCTEDPENT SISPGRELWF 
RKCRDGWRMK NETSPTVELP

Genular Protein ID: 2542691380

Symbol: B4DTR8_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DTR8

Database IDs:

Citations:

PubMed ID: 16177791

Title: DNA sequence and analysis of human chromosome 18.

PubMed ID: 16177791

DOI: 10.1038/nature03983

Sequence Information:

Length: 426
Mass: 48963
Checksum: 67509F7EC1BE4793
Sequence:

MSNSVPLLCF WSLCYCFAAG SPVPFGPEGR LEDKLHKPKA TQTEVKPSVR FNLRTSKDPE 
HEGCYLSVGH SQPLEDCSFN MTAKTFFIIH GWTMSGIFEN WLHKLVSALH TREKDANVVV 
VDWLPLAHQL YTDAVNNTRV VGHSIARMLD WLQEKDDFSL GNVHLIGYSL GAHVAGYAGN 
FVKGTVGRIT AITEVVKCEH ERAVHLFVDS LVNQDKPSFA FQCTDSNRFK KGICLSCRKN 
RCNSIGYNAK KMRNKRNSKM YLKTRAGMPF RVYHYQMKIH VFSYKNMGEI EPTFYVTLYG 
TNADSQTLPL EIVERIEQNA TNTFLVYTEE DLGDLLKIQL TWEGASQSWY NLWKEFRSYL 
SQPRNPGREL NIRRIRVKSG ETQRKLTFCT EDPENTSISP GRELWFRKCR DGWRMKNETS 
PTVELP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: LIPG

Associated with

Other Information

Cloning of a unique lipase from endothelial cells extends the lipase gene family. PubMed ID: 10318835

A novel endothelial-derived lipase that modulates HDL metabolism. PubMed ID: 10192396

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. PubMed ID: 12975309

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Characterization of the lipolytic activity of endothelial lipase. PubMed ID: 12032167

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. PubMed ID: 16335952

Identification of the active form of endothelial lipase, a homodimer in a head-to-tail conformation. PubMed ID: 19567873

Association of extreme blood lipid profile phenotypic variation with 11 reverse cholesterol transport genes and 10 non-genetic cardiovascular disease risk factors. PubMed ID: 12966036

DNA sequence and analysis of human chromosome 18. PubMed ID: 16177791