Details for: SLC22A13

Gene ID: 9390

Symbol: SLC22A13

Ensembl ID: ENSG00000172940

Description: solute carrier family 22 member 13

Associated with

Other Information

Genular Protein ID: 3249194324

Symbol: S22AD_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q9Y226 B2RCV9 Q8IYG1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 10 DMDM 1 DNASU 1 DisGeNET 1 EMBL 5 Ensembl 1 ExpressionAtlas 1 GO 12 Gene3D 1 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 1 RefSeq 1 Rhea 9 SAM 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 10072596

Title: Molecular cloning, mapping, and characterization of two novel human genes, ORCTL3 and ORCTL4, bearing homology to organic-cation transporters.

PubMed ID: 10072596

DOI: 10.1159/000015197

PubMed ID: 10231028

Title: Characterization of a 1200-kb genomic segment of chromosome 3p22-p21.3.

PubMed ID: 10231028

DOI: 10.1093/dnares/6.1.37

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18411268

Title: Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13).

PubMed ID: 18411268

DOI: 10.1074/jbc.m800737200

PubMed ID: 35144162

Title: Functional characterization of human organic anion transporter 10 (OAT10/SLC22A13) as an orotate transporter.

PubMed ID: 35144162

DOI: 10.1016/j.dmpk.2021.100443

PubMed ID: 31780526

Title: Dysfunctional missense variant of OAT10/SLC22A13 decreases gout risk and serum uric acid levels.

PubMed ID: 31780526

DOI: 10.1136/annrheumdis-2019-216044

PubMed ID: 35462902

Title: OAT10/SLC22A13 Acts as a Renal Urate Re-Absorber: Clinico-Genetic and Functional Analyses With Pharmacological Impacts.

PubMed ID: 35462902

DOI: 10.3389/fphar.2022.842717

Sequence Information:

  • Length: 551
  • Mass: 60862
  • Checksum: 80D69A0D5DDDA447
  • Sequence:
    • MAQFVQVLAE IGDFGRFQIQ LLILLCVLNF LSPFYFFAHV FMVLDEPHHC AVAWVKNHTF 
NLSAAEQLVL SVPLDTAGHP EPCLMFRPPP ANASLQDILS HRFNETQPCD MGWEYPENRL 
PSLKNEFNLV CDRKHLKDTT QSVFMAGLLV GTLMFGPLCD RIGRKATILA QLLLFTLIGL 
ATAFVPSFEL YMALRFAVAT AVAGLSFSNV TLLTEWVGPS WRTQAVVLAQ CNFSLGQMVL 
AGLAYGFRNW RLLQITGTAP GLLLFFYFWA LPESARWLLT RGRMDEAIQL IQKAASVNRR 
KLSPELMNQL VPEKTGPSGN ALDLFRHPQL RKVTLIIFCV WFVDSLGYYG LSLQVGDFGL 
DVYLTQLIFG AVEVPARCSS IFMMQRFGRK WSQLGTLVLG GLMCIIIIFI PADLPVVVTM 
LAVVGKMATA AAFTISYVYS AELFPTILRQ TGMGLVGIFS RIGGILTPLV ILLGEYHAAL 
PMLIYGSLPI VAGLLCTLLP ETHGQGLKDT LQDLELGPHP RSPKSVPSEK ETEAKGRTSS 
PGVAFVSSTY F

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.