Details for: RECQL5

Gene ID: 9400

Symbol: RECQL5

Ensembl ID: ENSG00000108469

Description: RecQ like helicase 5

Associated with

Other Information

Genular Protein ID: 3081010941

Symbol: RECQ5_HUMAN

Name: ATP-dependent DNA helicase Q5

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9878247

Title: Cloning of two new human helicase genes of the RecQ family: biological significance of multiple species in higher eukaryotes.

PubMed ID: 9878247

DOI: 10.1006/geno.1998.5595

PubMed ID: 10471747

Title: Drosophila and human RecQ5 exist in different isoforms generated by alternative splicing.

PubMed ID: 10471747

DOI: 10.1093/nar/27.18.3762

PubMed ID: 10710432

Title: Human RecQ5-beta, a large isomer of RecQ5 DNA helicase, localizes in the nucleoplasm and interacts with topoisomerases 3-alpha and 3-beta.

PubMed ID: 10710432

DOI: 10.1093/nar/28.7.1647

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20643585

Title: Human RECQL5 overcomes thymidine-induced replication stress.

PubMed ID: 20643585

DOI: 10.1016/j.dnarep.2010.06.009

PubMed ID: 20348101

Title: Physical interaction of RECQ5 helicase with RAD51 facilitates its anti-recombinase activity.

PubMed ID: 20348101

DOI: 10.1074/jbc.m110.110478

PubMed ID: 20231364

Title: RecQL5 promotes genome stabilization through two parallel mechanisms--interacting with RNA polymerase II and acting as a helicase.

PubMed ID: 20231364

DOI: 10.1128/mcb.01583-09

PubMed ID: 22973052

Title: Human RECQL5 participates in the removal of endogenous DNA damage.

PubMed ID: 22973052

DOI: 10.1091/mbc.e12-02-0110

PubMed ID: 22013166

Title: RECQL5 cooperates with Topoisomerase II alpha in DNA decatenation and cell cycle progression.

PubMed ID: 22013166

DOI: 10.1093/nar/gkr844

PubMed ID: 23715498

Title: The RecQ helicase RECQL5 participates in psoralen-induced interstrand cross-link repair.

PubMed ID: 23715498

DOI: 10.1093/carcin/bgt183

PubMed ID: 23180761

Title: RECQL5 plays co-operative and complementary roles with WRN syndrome helicase.

PubMed ID: 23180761

DOI: 10.1093/nar/gks1134

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 27502483

Title: RECQ5 helicase promotes resolution of conflicts between replication and transcription in human cells.

PubMed ID: 27502483

DOI: 10.1083/jcb.201507099

PubMed ID: 28575661

Title: RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis.

PubMed ID: 28575661

DOI: 10.1016/j.molcel.2017.05.006

PubMed ID: 23748380

Title: Structural mimicry in transcription regulation of human RNA polymerase II by the DNA helicase RECQL5.

PubMed ID: 23748380

DOI: 10.1038/nsmb.2596

Sequence Information:

  • Length: 991
  • Mass: 108858
  • Checksum: 983668133DED865A
  • Sequence:
  • MSSHHTTFPF DPERRVRSTL KKVFGFDSFK TPLQESATMA VVKGNKDVFV CMPTGAGKSL 
    CYQLPALLAK GITIVVSPLI ALIQDQVDHL LTLKVRVSSL NSKLSAQERK ELLADLEREK 
    PQTKILYITP EMAASSSFQP TLNSLVSRHL LSYLVVDEAH CVSQWGHDFR PDYLRLGALR 
    SRLGHAPCVA LTATATPQVQ EDVFAALHLK KPVAIFKTPC FRANLFYDVQ FKELISDPYG 
    NLKDFCLKAL GQEADKGLSG CGIVYCRTRE ACEQLAIELS CRGVNAKAYH AGLKASERTL 
    VQNDWMEEKV PVIVATISFG MGVDKANVRF VAHWNIAKSM AGYYQESGRA GRDGKPSWCR 
    LYYSRNDRDQ VSFLIRKEVA KLQEKRGNKA SDKATIMAFD ALVTFCEELG CRHAAIAKYF 
    GDALPACAKG CDHCQNPTAV RRRLEALERS SSWSKTCIGP SQGNGFDPEL YEGGRKGYGD 
    FSRYDEGSGG SGDEGRDEAH KREWNLFYQK QMQLRKGKDP KIEEFVPPDE NCPLKEASSR 
    RIPRLTVKAR EHCLRLLEEA LSSNRQSTRT ADEADLRAKA VELEHETFRN AKVANLYKAS 
    VLKKVADIHR ASKDGQPYDM GGSAKSCSAQ AEPPEPNEYD IPPASHVYSL KPKRVGAGFP 
    KGSCPFQTAT ELMETTRIRE QAPQPERGGE HEPPSRPCGL LDEDGSEPLP GPRGEVPGGS 
    AHYGGPSPEK KAKSSSGGSS LAKGRASKKQ QLLATAAHKD SQSIARFFCR RVESPALLAS 
    APEAEGACPS CEGVQGPPMA PEKYTGEEDG AGGHSPAPPQ TEECLRERPS TCPPRDQGTP 
    EVQPTPAKDT WKGKRPRSQQ ENPESQPQKR PRPSAKPSVV AEVKGSVSAS EQGTLNPTAQ 
    DPFQLSAPGV SLKEAANVVV KCLTPFYKEG KFASKELFKG FARHLSHLLT QKTSPGRSVK 
    EEAQNLIRHF FHGRARCESE ADWHGLCGPQ R

Genular Protein ID: 3264307730

Symbol: B3KQK2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 435
  • Mass: 48510
  • Checksum: D5BA50152C35EA25
  • Sequence:
  • MSSHHTTFPF DPERRVRSTL KKVFGFDSFK TPLQESATMA VVKGNKDVFV CMPTGAGKSL 
    CYQLPALLAK GNTIVVSPLI ALIQDQVDHL LTLKVRVSSL NSKLSAQERK ELLADLEREK 
    PQTKILYITP EMAASSSFQP TLNSLVSRHL LSYLVVDEAH CVSQWGHDFR PDYLRLGALR 
    SRLGHAPCVA LTATATPQVQ EDVFAALHLK KPVAIFKTPC FRANLFYDVQ FKELISDPYG 
    NLKDFCLKAL GQEADKGLSG CGIVYCRTRE ACEQLAIELS CRGVNAKAYH AGLKASERTL 
    VQNDWMEEKV PVIVATISFG MGVDKANVRF VAHWNIAKSM AGYYQESGRA GRDGKPSWCR 
    LYYSRNDRDQ VSFLIRKEVA KLQEKRGNKA SDKATIMAFD ALVTFCEELG RWGRGHGKSL 
    RAAWCSQVVS RHAEL

Genular Protein ID: 2243764382

Symbol: Q8WYH5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 586
  • Mass: 63844
  • Checksum: 3958D5E5C78E93C7
  • Sequence:
  • MFLVRCRHAA IAKYFGDALP ACAKGCDHCQ NPTAVRRRLE ALERSSSWSK TCIGPSQGNG 
    FDPELYEGGR KGYGDFSRYD EGSGGSGDEG RDEAHKREWN LFYQKQMQLR KGKDPKIEEF 
    VPPDENCPLK EASSRRIPRL TVKAREHCLR LLEEALSSNR QSTRTADEAD LRAKAVELEH 
    ETFRNAKVAN LYKASVLKKV ADIHRASKDG QPYDMGGSAK SCSAQAEPPE PNEYDIPPAS 
    HVYSLKPKRV GAGFPKGSCP FQTATELMET TRIREQAPQP ERGGEHEPPS RPCGLLDEDG 
    SEPLPGPRGE VPGGSAHYGG PSPEKKAKSS SGGSSLAKGR ASKKQQLLAT AAHKDSQSIA 
    RFFCRRVESP ALLASAPEAE GACPSCEGVQ GPPMAPEKYT GEEDGAGGHS PAPPQTEECL 
    RERPSTCPPR DQGTPEVQPT PAKDTWKGKR PRSQQENPES QPQKRPRPSA KPSVVAEVKG 
    SVSASEQGTL NPTAQDPFQL SAPGVSLKEA ANVVVKCLTP FYKEGKFASK ELFKGFARHL 
    SHLLTQKTSP GRSVKEEAQN LIRHFFHGRA RCESEADWHG LCGPQR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.