Details for: PEX16

Gene ID: 9409

Symbol: PEX16

Ensembl ID: ENSG00000121680

Description: peroxisomal biogenesis factor 16

Associated with

Other Information

Genular Protein ID: 1670156209

Symbol: PEX16_HUMAN

Name: Peroxisomal membrane protein PEX16

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9837814

Title: Mutation in PEX16 is causal in the peroxisome-deficient Zellweger syndrome of complementation group D.

PubMed ID: 9837814

DOI: 10.1086/302161

PubMed ID: 9922452

Title: Peroxisome synthesis in the absence of preexisting peroxisomes.

PubMed ID: 9922452

DOI: 10.1083/jcb.144.2.255

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10704444

Title: PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis.

PubMed ID: 10704444

DOI: 10.1083/jcb.148.5.931

PubMed ID: 11390669

Title: Human pex19p binds peroxisomal integral membrane proteins at regions distinct from their sorting sequences.

PubMed ID: 11390669

DOI: 10.1128/mcb.21.13.4413-4424.2001

PubMed ID: 12223482

Title: The membrane biogenesis peroxin Pex16p. Topogenesis and functional roles in peroxisomal membrane assembly.

PubMed ID: 12223482

DOI: 10.1074/jbc.m206139200

PubMed ID: 14709540

Title: PEX19 is a predominantly cytosolic chaperone and import receptor for class 1 peroxisomal membrane proteins.

PubMed ID: 14709540

DOI: 10.1083/jcb.200304111

PubMed ID: 16717127

Title: The origin and maintenance of mammalian peroxisomes involves a de novo PEX16-dependent pathway from the ER.

PubMed ID: 16717127

DOI: 10.1083/jcb.200601036

PubMed ID: 21768384

Title: Sec16B is involved in the endoplasmic reticulum export of the peroxisomal membrane biogenesis factor peroxin 16 (Pex16) in mammalian cells.

PubMed ID: 21768384

DOI: 10.1073/pnas.1103283108

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 20647552

Title: Identification of an unusual variant peroxisome biogenesis disorder caused by mutations in the PEX16 gene.

PubMed ID: 20647552

DOI: 10.1136/jmg.2009.074302

Sequence Information:

  • Length: 336
  • Mass: 38629
  • Checksum: 57243AEE0B165C59
  • Sequence:
  • MEKLRLLGLR YQEYVTRHPA ATAQLETAVR GFSYLLAGRF ADSHELSELV YSASNLLVLL 
    NDGILRKELR KKLPVSLSQQ KLLTWLSVLE CVEVFMEMGA AKVWGEVGRW LVIALVQLAK 
    AVLRMLLLLW FKAGLQTSPP IVPLDRETQA QPPDGDHSPG NHEQSYVGKR SNRVVRTLQN 
    TPSLHSRHWG APQQREGRQQ QHHEELSATP TPLGLQETIA EFLYIARPLL HLLSLGLWGQ 
    RSWKPWLLAG VVDVTSLSLL SDRKGLTRRE RRELRRRTIL LLYYLLRSPF YDRFSEARIL 
    FLLQLLADHV PGVGLVTRPL MDYLPTWQKI YFYSWG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.