Details for: TJP2

Gene ID: 9414

Symbol: TJP2

Ensembl ID: ENSG00000119139

Description: tight junction protein 2

Associated with

Other Information

Genular Protein ID: 3180052048

Symbol: ZO2_HUMAN

Name: Tight junction protein ZO-2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7951235

Title: The Friedreich ataxia region: characterization of two novel genes and reduction of the critical region to 300 kb.

PubMed ID: 7951235

DOI: 10.1093/hmg/3.6.909

PubMed ID: 11018256

Title: Organization and expression of the human zo-2 gene (tjp-2) in normal and neoplastic tissues.

PubMed ID: 11018256

DOI: 10.1016/s0167-4781(00)00185-8

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10360833

Title: Tight junction protein ZO-2 is differentially expressed in normal pancreatic ducts compared to human pancreatic adenocarcinoma.

PubMed ID: 10360833

DOI: 10.1002/(sici)1097-0215(19990702)82:1<137::aid-ijc23>3.0.co;2-f

PubMed ID: 10495427

Title: Zo-2 gene alternative promoters in normal and neoplastic human pancreatic duct cells.

PubMed ID: 10495427

DOI: 10.1002/(sici)1097-0215(19991029)83:3<349::aid-ijc10>3.0.co;2-c

PubMed ID: 15975580

Title: hScrib interacts with ZO-2 at the cell-cell junctions of epithelial cells.

PubMed ID: 15975580

DOI: 10.1016/j.febslet.2005.05.062

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 18823282

Title: Characterization of the ubinuclein protein as a new member of the nuclear and adhesion complex components (NACos).

PubMed ID: 18823282

DOI: 10.1042/bc20080072

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24614073

Title: Mutations in TJP2 cause progressive cholestatic liver disease.

PubMed ID: 24614073

DOI: 10.1038/ng.2918

PubMed ID: 17897942

Title: Domain-swapped dimerization of the second PDZ domain of ZO2 may provide a structural basis for the polymerization of claudins.

PubMed ID: 17897942

DOI: 10.1074/jbc.m703826200

PubMed ID: 12704386

Title: Complex inheritance of familial hypercholanemia with associated mutations in TJP2 and BAAT.

PubMed ID: 12704386

DOI: 10.1038/ng1147

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 1190
  • Mass: 133958
  • Checksum: 27305B723043BF6C
  • Sequence:
  • MPVRGDRGFP PRRELSGWLR APGMEELIWE QYTVTLQKDS KRGFGIAVSG GRDNPHFENG 
    ETSIVISDVL PGGPADGLLQ ENDRVVMVNG TPMEDVLHSF AVQQLRKSGK VAAIVVKRPR 
    KVQVAALQAS PPLDQDDRAF EVMDEFDGRS FRSGYSERSR LNSHGGRSRS WEDSPERGRP 
    HERARSRERD LSRDRSRGRS LERGLDQDHA RTRDRSRGRS LERGLDHDFG PSRDRDRDRS 
    RGRSIDQDYE RAYHRAYDPD YERAYSPEYR RGARHDARSR GPRSRSREHP HSRSPSPEPR 
    GRPGPIGVLL MKSRANEEYG LRLGSQIFVK EMTRTGLATK DGNLHEGDII LKINGTVTEN 
    MSLTDARKLI EKSRGKLQLV VLRDSQQTLI NIPSLNDSDS EIEDISEIES NRSFSPEERR 
    HQYSDYDYHS SSEKLKERPS SREDTPSRLS RMGATPTPFK STGDIAGTVV PETNKEPRYQ 
    EDPPAPQPKA APRTFLRPSP EDEAIYGPNT KMVRFKKGDS VGLRLAGGND VGIFVAGIQE 
    GTSAEQEGLQ EGDQILKVNT QDFRGLVRED AVLYLLEIPK GEMVTILAQS RADVYRDILA 
    CGRGDSFFIR SHFECEKETP QSLAFTRGEV FRVVDTLYDG KLGNWLAVRI GNELEKGLIP 
    NKSRAEQMAS VQNAQRDNAG DRADFWRMRG QRSGVKKNLR KSREDLTAVV SVSTKFPAYE 
    RVLLREAGFK RPVVLFGPIA DIAMEKLANE LPDWFQTAKT EPKDAGSEKS TGVVRLNTVR 
    QIIEQDKHAL LDVTPKAVDL LNYTQWFPIV IFFNPDSRQG VKTMRQRLNP TSNKSSRKLF 
    DQANKLKKTC AHLFTATINL NSANDSWFGS LKDTIQHQQG EAVWVSEGKM EGMDDDPEDR 
    MSYLTAMGAD YLSCDSRLIS DFEDTDGEGG AYTDNELDEP AEEPLVSSIT RSSEPVQHEE 
    SIRKPSPEPR AQMRRAASSD QLRDNSPPPA FKPEPPKAKT QNKEESYDFS KSYEYKSNPS 
    AVAGNETPGA STKGYPPPVA AKPTFGRSIL KPSTPIPPQE GEEVGESSEE QDNAPKSVLG 
    KVKIFEKMDH KARLQRMQEL QEAQNARIEI AQKHPDIYAV PIKTHKPDPG TPQHTSSRPP 
    EPQKAPSRPY QDTRGSYGSD AEEEEYRQQL SEHSKRGYYG QSARYRDTEL

Genular Protein ID: 2732275513

Symbol: B7Z2R3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 1020
  • Mass: 115182
  • Checksum: 4A49E60A1AF73901
  • Sequence:
  • MEELIWEQYT VTLQKDSKRG FGIAVSGGRD NPHFENGETS IVISDVLPGG PADGLLQEND 
    RVVMVNGTPM EDVLHSFAVQ QLRKSGKVAA IVVKRPRKVQ VAALQASPPL DQDDRAFEVM 
    DEFDGRSFRS GYSERSRLNS HGGRSRSWED SPERGRPHER ARSRERDLSR DRSRGRSLER 
    GLDQDHARTR DRSRGRSLER GLDHDFGPSR DRDRDRSRGR SIDQDYERAY HRAYDPDYER 
    AYSPEYRRGA RHDARSRGPR SRSREHPHSR SPSPEPRGRP GPIGVLLMKS RANEEYGLRL 
    GSQIFVKEMT RTGLATKDGN LHEGDIILKI NGTVTENMSL TDARKLIEKS RGKLQLVVLR 
    DSQQTLINIP SLNDSDSEIE DISEIESNRS FSPEERRHQY SDYDYHSSSE KLKERPSSRE 
    DTPSRLSRMG ATPTPFKSTG DIAGTVVPET NKEPRYQEEP PAPQPKAAPR TFLRPSPEDE 
    AIYGPNTKMV RFKKGDSVGL RLAGGNDVGI FVAGIQEGTS AEQEGLQEGD QILKVNTQDF 
    RGLVREDAVL YLLEIPKGEM VTILAQSRAD VYRDILACGR GDSFFIRSHF ECEKETPQSL 
    AFTRGEVFRV VDTLYDGKLG NWLAVRIGNE LEKGLIPNKS RAEQMASVQN AQRDNAGDRA 
    DFWRMRGQRS GVKKNLRKSR EDLTAVVSVS TKFPAYERVL LREAGFKRPV VLFGPIADIA 
    MEKLANELPD WFQTAKTEPK DAGSEKSTGV VRLNTVRQII EQDKHALLDV TPKAVDLLNY 
    TQWFPIVIFF NPDSRQGVKT MRQRLNPTSN KSSRKLFDQA NKLKKTCAHL FTATINLNSA 
    NDSWFGSLKD TIQHQQGEAV WVSEGKMEGM DDDPEDRMSY LTAMGADYLS CDSRLISDFE 
    DTDGEGGAYT DNELDEPAEE PLVSSITRSS EPVQHEEIEI AQKHPDIYAV PIKTHKPDPG 
    TPQHTSSRPP EPQKAPSRPY QDTRGSYGSD AEEEEYRQQL SEHSKRGYYG QSARYRDTEL

Genular Protein ID: 2399937540

Symbol: B7Z954_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 1108
  • Mass: 124877
  • Checksum: 48E0C9A0AE2C985D
  • Sequence:
  • MEELIWEQYT VTLQKDSKRG FGIAVSGGRD NPHFENGETS IVISDVLPGG PADGLLQEND 
    RVVMVNGTLM EDVLHSFAVQ QLRKSGKVAA IVVKRPRKVQ VAALQASPPL DQDDRAFEVM 
    DEFDGRSFRS GYSERSRLNS HGGRSRSWED SPERGRPHER ARSRERDLSR DRSRGRSLER 
    GLDQDHARTR DRSRGRSLER GLDHDFGPSR DRDRDRSRGR SIDQDYERAY HRAYDPDYER 
    AYSPEYRRGA RHDARSRGPR SRSREHPHSR SPSPEPRGRP GPIGVLLMKS RANEEYGLRL 
    GSQIFVKEMT RTGLATKDGN LHEGDIILKI NGTVTENMSL TDARKLIEKS RGKLQLVVLR 
    DSQQTLINIP SLNDSDSEIE DISEIESNRS FSPEERRHQY SDYDYHSSSE KLKERPSSRE 
    DTPSRLSRMG ATPTPFKSTG DIAGTVVPET NKEPRYQEDP PAPQPKAAPR TFLRPSPEDE 
    AIYGPNTKMV RFKKGDSVGL RLAGGNDVGI FVAGIQEGTS AEQEGLQEGD QILKVNTQDF 
    RGLVREDAVL YLLEIPKGEM VTILAQSRAD VYRDILACGR GDSFFIRSHF ECEKETPQSL 
    AFTRGEVFRV VDTLYDGKLG NWLAVRIGNE LEKGLIPNKS RAEQMASVQN AQRDNAGDRA 
    DFWRMRGQRS GVKKNLRKSR EDLTAVVSVS TKFPAYERVL LREAGFKRPV VLFGPIADIA 
    MEKLANELPD WFQTAKTEPK DAGSEKSTGV VRLNTVRQII EQDKHALLDV TPKAVDLLNY 
    TQWFPIVIFF NPDSRQGVKT MRQRLNPTSN KSSRKLFDQA NKLKKTCAHL FTATINLNSA 
    NDSWFGSLKD TDNELDEPAE EPLVSSITRS SEPVQHEESI RKPSPEPRAQ MRRAASSDQL 
    RDNSPPPAFK PEPPKAKTQN KEESYDFSKS YEYKSNPSAV AGNETPGAST KGYPPPVAAK 
    PTFGRSILKP STPIPPQEGE EVGESSEEQD NAPKSVLGKV KIFEKMDHKA RLQRMQELQE 
    AQNARIEIAQ KHPDIYAVPI KTHKPDPGTP QHTSSRPPEP QKAPSRPYQD TRGSYGSDAE 
    EEEYRQQLSE HSKRGYYGQS ARYRDTEL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.