Details for: CD86

Gene ID: 942

Symbol: CD86

Ensembl ID: ENSG00000114013

Description: CD86 molecule

Associated with

Other Information

Genular Protein ID: 353467806

Symbol: CD86_HUMAN

Name: T-lymphocyte activation antigen CD86

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7694153

Title: B70 antigen is a second ligand for CTLA-4 and CD28.

PubMed ID: 7694153

DOI: 10.1038/366076a0

PubMed ID: 7694363

Title: Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation.

PubMed ID: 7694363

DOI: 10.1126/science.7694363

PubMed ID: 11162656

Title: Identification of an alternatively spliced variant of human CD86 mRNA.

PubMed ID: 11162656

DOI: 10.1006/bbrc.2000.4102

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7541777

Title: Genomic organization of the gene coding for the costimulatory human B-lymphocyte antigen B7-2 (CD86).

PubMed ID: 7541777

DOI: 10.1007/bf00178582

PubMed ID: 7527824

Title: CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL.

PubMed ID: 7527824

PubMed ID: 7520767

Title: The B7-2 (B70) costimulatory molecule expressed by monocytes and activated B lymphocytes is the CD86 differentiation antigen.

PubMed ID: 7520767

PubMed ID: 12582153

Title: c-MIR, a human E3 ubiquitin ligase, is a functional homolog of herpesvirus proteins MIR1 and MIR2 and has similar activity.

PubMed ID: 12582153

DOI: 10.1074/jbc.m211285200

PubMed ID: 16920215

Title: Members of adenovirus species B utilize CD80 and CD86 as cellular attachment receptors.

PubMed ID: 16920215

DOI: 10.1016/j.virusres.2006.07.009

PubMed ID: 30918073

Title: By Binding CD80 and CD86, the Vaccinia Virus M2 Protein Blocks Their Interactions with both CD28 and CTLA4 and Potentiates CD80 Binding to PD-L1.

PubMed ID: 30918073

DOI: 10.1128/jvi.00207-19

PubMed ID: 11279501

Title: Structural basis for co-stimulation by the human CTLA-4/B7-2 complex.

PubMed ID: 11279501

DOI: 10.1038/35069112

PubMed ID: 12606712

Title: Crystal structure of the receptor-binding domain of human B7-2: insights into organization and signaling.

PubMed ID: 12606712

DOI: 10.1073/pnas.252771499

Sequence Information:

  • Length: 329
  • Mass: 37682
  • Checksum: C249DAEEB889D911
  • Sequence:
  • MDPQCTMGLS NILFVMAFLL SGAAPLKIQA YFNETADLPC QFANSQNQSL SELVVFWQDQ 
    ENLVLNEVYL GKEKFDSVHS KYMGRTSFDS DSWTLRLHNL QIKDKGLYQC IIHHKKPTGM 
    IRIHQMNSEL SVLANFSQPE IVPISNITEN VYINLTCSSI HGYPEPKKMS VLLRTKNSTI 
    EYDGVMQKSQ DNVTELYDVS ISLSVSFPDV TSNMTIFCIL ETDKTRLLSS PFSIELEDPQ 
    PPPDHIPWIT AVLPTVIICV MVFCLILWKW KKKKRPRNSY KCGTNTMERE ESEQTKKREK 
    IHIPERSDEA QRVFKSSKTS SCDKSDTCF

Genular Protein ID: 3962049152

Symbol: A8K632_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 329
  • Mass: 37756
  • Checksum: 7EDE533873336FCC
  • Sequence:
  • MDPQCTMGLS NILFVMAFLL SGAAPLKIQA YFNETADLPC QFANSQNQSL SELVVFWQDQ 
    ENLVLNEVYL GKEKFDSVHS KYMGRTSFDS DSWTLRLHNL QIKDKGLYQC IIHHKKPTGM 
    IRIHQMNFEL SVLANFSQPE IVPISNITEN VYINLTCSSI HGYPEPKKMS VLLRTKNSTI 
    EYDGIMQKSQ DNVTELYDVS ISLSVSFPDV TSNMTIFCIL ETDKTRLLSS PFSIELEDPQ 
    PPPDHIPWIT AVLPTVIICV MVFCLILWKW KKKKRPRNSY KCGTNTMERE ESEQTKKREK 
    IHIPERSDEA QRVFKSSKTS SCDKSDTCF

Genular Protein ID: 2914387160

Symbol: A0A0X9R4E0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

Sequence Information:

  • Length: 323
  • Mass: 37021
  • Checksum: 030FEE69089B73DB
  • Sequence:
  • MGLSNILFVM AFLLSGAAPL KIQAYFNETA DLPCQFANSQ NQSLSELVVF WQDQENLVLN 
    EVYLGKEKFD SVHSKYMGRT SFDSDSWTLR LHNLQIKDKG LYQCIIHHKK PTGMIRIHQM 
    NSELSVLANF SQPEIVPISN ITENVYINLT CSSIHGYPEP KKMSVLLRTK NSTIEYDGIM 
    QKSQDNVTEL YDVSISLSVS FPDVTSNMTI FCILETDKTR LLSSPFSIEL EDPQPPPDHI 
    PWITAVLPTV IICVMVFCLI LWKWKKKKRP RNSYKCGTNT MEREESEQTK KREKIHIPER 
    SDEAQRVFKS SKTSSCDKSD TCF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.