Details for: TNFRSF8
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 14.8510
Cell Significance Index: -2.3100 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 9.0678
Cell Significance Index: -2.3000 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 5.6122
Cell Significance Index: -2.2800 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 4.8796
Cell Significance Index: -2.5100 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 1.8735
Cell Significance Index: -2.3100 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 1.0098
Cell Significance Index: -2.2100 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 0.7553
Cell Significance Index: -2.3200 - Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: 0.4497
Cell Significance Index: 5.8100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.3213
Cell Significance Index: 10.2900 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: 0.3184
Cell Significance Index: 7.9400 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.2849
Cell Significance Index: 10.7900 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.2655
Cell Significance Index: 4.5500 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.2182
Cell Significance Index: 3.5000 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.1965
Cell Significance Index: 5.7700 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.1947
Cell Significance Index: 8.6100 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.1095
Cell Significance Index: 2.9400 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.0557
Cell Significance Index: 1.4700 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.0497
Cell Significance Index: 0.9700 - Cell Name: thymocyte (CL0000893)
Fold Change: 0.0467
Cell Significance Index: 0.5900 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.0457
Cell Significance Index: 1.0000 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.0379
Cell Significance Index: 0.6700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0214
Cell Significance Index: 4.3000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0179
Cell Significance Index: 3.0500 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0158
Cell Significance Index: 3.1300 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.0135
Cell Significance Index: 0.2500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.0087
Cell Significance Index: 1.2700 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0058
Cell Significance Index: 2.0700 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0026
Cell Significance Index: 4.8600 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.0021
Cell Significance Index: 0.0300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0012
Cell Significance Index: 1.8000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0008
Cell Significance Index: 1.4500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0002
Cell Significance Index: 0.2300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0006
Cell Significance Index: -0.1100 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.0006
Cell Significance Index: -0.0100 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0010
Cell Significance Index: -0.6100 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0022
Cell Significance Index: -1.0200 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0030
Cell Significance Index: -2.3000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0031
Cell Significance Index: -2.2700 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0041
Cell Significance Index: -2.3100 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0043
Cell Significance Index: -2.3700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0048
Cell Significance Index: -1.3700 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: -0.0070
Cell Significance Index: -0.0600 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0083
Cell Significance Index: -0.9800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0087
Cell Significance Index: -1.2000 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: -0.0092
Cell Significance Index: -0.1200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0110
Cell Significance Index: -1.1300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0115
Cell Significance Index: -2.4200 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0118
Cell Significance Index: -1.5100 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.0129
Cell Significance Index: -0.3700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0131
Cell Significance Index: -1.6100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0163
Cell Significance Index: -1.8700 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.0167
Cell Significance Index: -0.2400 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0174
Cell Significance Index: -2.2500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0203
Cell Significance Index: -2.1100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0211
Cell Significance Index: -1.4200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0211
Cell Significance Index: -1.6200 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0236
Cell Significance Index: -1.4500 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.0247
Cell Significance Index: -0.7800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0305
Cell Significance Index: -2.2700 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0309
Cell Significance Index: -1.4500 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0358
Cell Significance Index: -1.5600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0368
Cell Significance Index: -1.9100 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0381
Cell Significance Index: -2.4600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0394
Cell Significance Index: -2.2100 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.0406
Cell Significance Index: -1.0900 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0407
Cell Significance Index: -1.3000 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0437
Cell Significance Index: -1.4300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0441
Cell Significance Index: -2.0000 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0454
Cell Significance Index: -1.5900 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0509
Cell Significance Index: -1.0800 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0520
Cell Significance Index: -2.4300 - Cell Name: lung microvascular endothelial cell (CL2000016)
Fold Change: -0.0532
Cell Significance Index: -0.4500 - Cell Name: acinar cell (CL0000622)
Fold Change: -0.0541
Cell Significance Index: -0.6800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0551
Cell Significance Index: -1.4700 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.0594
Cell Significance Index: -1.4400 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.0602
Cell Significance Index: -1.3000 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.0610
Cell Significance Index: -2.1200 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0615
Cell Significance Index: -1.7200 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0617
Cell Significance Index: -1.7600 - Cell Name: precursor B cell (CL0000817)
Fold Change: -0.0618
Cell Significance Index: -0.8000 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.0625
Cell Significance Index: -1.5600 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: -0.0655
Cell Significance Index: -1.2800 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.0683
Cell Significance Index: -1.3500 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.0692
Cell Significance Index: -1.3900 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.0693
Cell Significance Index: -1.7700 - Cell Name: cytotoxic T cell (CL0000910)
Fold Change: -0.0700
Cell Significance Index: -1.0200 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: -0.0751
Cell Significance Index: -0.6500 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.0760
Cell Significance Index: -2.7900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0763
Cell Significance Index: -2.6800 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.0771
Cell Significance Index: -2.2700 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: -0.0778
Cell Significance Index: -1.1300 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: -0.0811
Cell Significance Index: -1.0400 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: -0.0814
Cell Significance Index: -0.8900 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.0816
Cell Significance Index: -1.6600 - Cell Name: proerythroblast (CL0000547)
Fold Change: -0.0816
Cell Significance Index: -1.1700 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.0821
Cell Significance Index: -1.9700 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0825
Cell Significance Index: -2.1200 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.0830
Cell Significance Index: -1.2300 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.0841
Cell Significance Index: -1.7600 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0875
Cell Significance Index: -1.8200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1536398073
Symbol: TNR8_HUMAN
Name: CD30L receptor
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1310894
Title: Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease.
PubMed ID: 1310894
PubMed ID: 7527901
Title: Opposite effects of the CD30 ligand are not due to CD30 mutations: results from cDNA cloning and sequence comparison of the CD30 antigen from different sources.
PubMed ID: 7527901
PubMed ID: 8839832
Title: A variant CD30 protein lacking extracellular and transmembrane domains is induced in HL-60 by tetradecanoylphorbol acetate and is expressed in alveolar macrophages.
PubMed ID: 8839832
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8391931
Title: CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF.
PubMed ID: 8391931
PubMed ID: 8627180
Title: T cell receptor-dependent cell death of T cell hybridomas mediated by the CD30 cytoplasmic domain in association with tumor necrosis factor receptor-associated factors.
PubMed ID: 8627180
PubMed ID: 9168896
Title: Binding sites of cytoplasmic effectors TRAF1, 2, and 3 on CD30 and other members of the TNF receptor superfamily.
PubMed ID: 9168896
PubMed ID: 9511754
Title: Cloning and characterization of a cDNA encoding the human homolog of tumor necrosis factor receptor-associated factor 5 (TRAF5).
PubMed ID: 9511754
PubMed ID: 8999898
Title: Tumor necrosis factor receptor-associated factor (TRAF) 5 and TRAF2 are involved in CD30-mediated NFkappaB activation.
PubMed ID: 8999898
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 10518213
Title: The structural basis for the recognition of diverse receptor sequences by TRAF2.
PubMed ID: 10518213
Sequence Information:
- Length: 595
- Mass: 63747
- Checksum: 7A407CC78A6E0BC8
- Sequence:
MRVLLAALGL LFLGALRAFP QDRPFEDTCH GNPSHYYDKA VRRCCYRCPM GLFPTQQCPQ RPTDCRKQCE PDYYLDEADR CTACVTCSRD DLVEKTPCAW NSSRVCECRP GMFCSTSAVN SCARCFFHSV CPAGMIVKFP GTAQKNTVCE PASPGVSPAC ASPENCKEPS SGTIPQAKPT PVSPATSSAS TMPVRGGTRL AQEAASKLTR APDSPSSVGR PSSDPGLSPT QPCPEGSGDC RKQCEPDYYL DEAGRCTACV SCSRDDLVEK TPCAWNSSRT CECRPGMICA TSATNSCARC VPYPICAAET VTKPQDMAEK DTTFEAPPLG TQPDCNPTPE NGEAPASTSP TQSLLVDSQA SKTLPIPTSA PVALSSTGKP VLDAGPVLFW VILVLVVVVG SSAFLLCHRR ACRKRIRQKL HLCYPVQTSQ PKLELVDSRP RRSSTQLRSG ASVTEPVAEE RGLMSQPLME TCHSVGAAYL ESLPLQDASP AGGPSSPRDL PEPRVSTEHT NNKIEKIYIM KADTVIVGTV KAELPEGRGL AGPAEPELEE ELEADHTPHY PEQETEPPLG SCSDVMLSVE EEGKEDPLPT AASGK
Genular Protein ID: 4112690478
Symbol: A5D8T4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 187
- Mass: 20415
- Checksum: C8468011380824D4
- Sequence:
RRACRKRIRQ KLHLCYPVQT SQPKLELVDS RPRRSSTQLR SGASVTEPVA EERGLMSQPL METCHSVGAA YLESLPLQDA SPAGGPSSPR DLPEPRVSTE HTNNKIEKIY IMKADTVIVG TVKAELPEGR GLAGPAEPEL EEELEADHTP HYPEQETEPP LGSCSDVMLS VEEEGKEDPL PTAASGK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.