Details for: MAP4K4
Associated with
Other Information
Genular Protein ID: 482078481
Symbol: M4K4_HUMAN
Name: Mitogen-activated protein kinase kinase kinase kinase 4
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9890973
Title: A novel human STE20-related protein kinase, HGK, that specifically activates the c-Jun N-terminal kinase signaling pathway.
PubMed ID: 9890973
PubMed ID: 12612079
Title: The STE20 kinase HGK is broadly expressed in human tumor cells and can modulate cellular transformation, invasion, and adhesion.
PubMed ID: 12612079
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 9734811
Title: Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.
PubMed ID: 9734811
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 12387898
Title: A novel GTP-binding protein hGBP3 interacts with NIK/HGK.
PubMed ID: 12387898
PubMed ID: 14966141
Title: Mitogen-activated protein kinase kinase kinase kinase 4 as a putative effector of Rap2 to activate the c-Jun N-terminal kinase.
PubMed ID: 14966141
PubMed ID: 18220336
Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.
PubMed ID: 18220336
DOI: 10.1021/pr0705441
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21690388
Title: Smad inhibition by the Ste20 kinase Misshapen.
PubMed ID: 21690388
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 17344846
Title: Patterns of somatic mutation in human cancer genomes.
PubMed ID: 17344846
DOI: 10.1038/nature05610
Sequence Information:
- Length: 1239
- Mass: 142101
- Checksum: 8FBBE2F9ABEEC757
- Sequence:
MANDSPAKSL VDIDLSSLRD PAGIFELVEV VGNGTYGQVY KGRHVKTGQL AAIKVMDVTE DEEEEIKLEI NMLKKYSHHR NIATYYGAFI KKSPPGHDDQ LWLVMEFCGA GSITDLVKNT KGNTLKEDWI AYISREILRG LAHLHIHHVI HRDIKGQNVL LTENAEVKLV DFGVSAQLDR TVGRRNTFIG TPYWMAPEVI ACDENPDATY DYRSDLWSCG ITAIEMAEGA PPLCDMHPMR ALFLIPRNPP PRLKSKKWSK KFFSFIEGCL VKNYMQRPST EQLLKHPFIR DQPNERQVRI QLKDHIDRTR KKRGEKDETE YEYSGSEEEE EEVPEQEGEP SSIVNVPGES TLRRDFLRLQ QENKERSEAL RRQQLLQEQQ LREQEEYKRQ LLAERQKRIE QQKEQRRRLE EQQRREREAR RQQEREQRRR EQEEKRRLEE LERRRKEEEE RRRAEEEKRR VEREQEYIRR QLEEEQRHLE VLQQQLLQEQ AMLLECRWRE MEEHRQAERL QRQLQQEQAY LLSLQHDHRR PHPQHSQQPP PPQQERSKPS FHAPEPKAHY EPADRAREVE DRFRKTNHSS PEAQSKQTGR VLEPPVPSRS ESFSNGNSES VHPALQRPAE PQVPVRTTSR SPVLSRRDSP LQGSGQQNSQ AGQRNSTSIE PRLLWERVEK LVPRPGSGSS SGSSNSGSQP GSHPGSQSGS GERFRVRSSS KSEGSPSQRL ENAVKKPEDK KEVFRPLKPA DLTALAKELR AVEDVRPPHK VTDYSSSSEE SGTTDEEDDD VEQEGADEST SGPEDTRAAS SLNLSNGETE SVKTMIVHDD VESEPAMTPS KEGTLIVRQT QSASSTLQKH KSSSSFTPFI DPRLLQISPS SGTTVTSVVG FSCDGMRPEA IRQDPTRKGS VVNVNPTNTR PQSDTPEIRK YKKRFNSEIL CAALWGVNLL VGTESGLMLL DRSGQGKVYP LINRRRFQQM DVLEGLNVLV TISGKKDKLR VYYLSWLRNK ILHNDPEVEK KQGWTTVGDL EGCVHYKVVK YERIKFLVIA LKSSVEVYAW APKPYHKFMA FKSFGELVHK PLLVDLTVEE GQRLKVIYGS CAGFHAVDVD SGSVYDIYLP THIQCSIKPH AIIILPNTDG MELLVCYEDE GVYVNTYGRI TKDVVLQWGE MPTSVAYIRS NQTMGWGEKA IEIRSVETGH LDGVFMHKRA QRLKFLCERN DKVFFASVRS GGSSQVYFMT LGRTSLLSW
Genular Protein ID: 3301076805
Symbol: E7EN19_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 18220336
Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.
PubMed ID: 18220336
DOI: 10.1021/pr0705441
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 1235
- Mass: 141066
- Checksum: 34858B06EBF7D9A3
- Sequence:
MANDSPAKSL VDIDLSSLRD PAGIFELVEV VGNGTYGQVY KGRHVKTGQL AAIKVMDVTE DEEEEIKLEI NMLKKYSHHR NIATYYGAFI KKSPPGHDDQ LWLVMEFCGA GSITDLVKNT KGNTLKEDWI AYISREILRG LAHLHIHHVI HRDIKGQNVL LTENAEVKLV DFGVSAQLDR TVGRRNTFIG TPYWMAPEVI ACDENPDATY DYRSDLWSCG ITAIEMAEGA PPLCDMHPMR ALFLIPRNPP PRLKSKKWSK KFFSFIEGCL VKNYMQRPST EQLLKHPFIR DQPNERQVRI QLKDHIDRTR KKRGEKDETE YEYSGSEEEE EEVPEQEGEP SSIVNVPGES TLRRDFLRLQ QENKERSEAL RRQQLLQEQQ LREQEEYKRQ LLAERQKRIE QQKEQRRRLE EQQRREREAR RQQEREQRRR EQEEKRRLEE LERRRKEEEE RRRAEEEKRR VEREQEYIRR QLEEEQRHLE VLQQQLLQEQ AMLLHDHRRP HPQHSQQPPP PQQERSKPSF HAPEPKAHYE PADRAREVQW SHLASLKNNV SPVSRSHSFS DPSPKFAHHH LRSQDPCPPS RSEVLSQSSD SKSEAPDPTQ KAWSRSDSDE VPPRVPVRTT SRSPVLSRRD SPLQGSGQQN SQAGQRNSTS SIEPRLLWER VEKLVPRPGS GSSSGSSNSG SQPGSHPGSQ SGSGERFRVR SSSKSEGSPS QRLENAVKKP EDKKEVFRPL KPAGEVDLTA LAKELRAVED VRPPHKVTDY SSSSEESGTT DEEDDDVEQE GADESTSGPE DTRAASSLNL SNGETESVKT MIVHDDVESE PAMTPSKEGT LIVRQTQSAS STLQKHKSSS SFTPFIDPRL LQISPSSGTT VTSVVGFSCD GMRPEAIRQD PTRKGSVVNV NPTNTRPQSD TPEIRKYKKR FNSEILCAAL WGVNLLVGTE SGLMLLDRSG QGKVYPLINR RRFQQMDVLE GLNVLVTISG KKDKLRVYYL SWLRNKILHN DPEVEKKQGW TTVGDLEGCV HYKVVKYERI KFLVIALKSS VEVYAWAPKP YHKFMAFKSF GELVHKPLLV DLTVEEGQRL KVIYGSCAGF HAVDVDSGSV YDIYLPTHIQ CSIKPHAIII LPNTDGMELL VCYEDEGVYV NTYGRITKDV VLQWGEMPTS VAYIRSNQTM GWGEKAIEIR SVETGHLDGV FMHKRAQRLK FLCERNDKVF FASVRSGGSS QVYFMTLGRT SLLSW
Genular Protein ID: 1912158221
Symbol: V9HWH3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 1212
- Mass: 138505
- Checksum: 29398FB628EE847F
- Sequence:
MANDSPAKSL VDIDLSSLRD PAGIFELVEV VGNGTYGQVY KGRHVKTGQL AAIKVMDVTE DEEEEIKLEI NMLKKYSHHR NIATYYGAFI KKSPPGHDDQ LWLVMEFCGA GSITDLVKNT KGNTLKEDWI AYISREILRG LAHLHIHHVI HRDIKGQNVL LTENAEVKLV DFGVSAQLDR TVGRRNTFIG TPYWMAPEVI ACDENPDATY DYRSDLWSCG ITAIEMAEGA PPLCDMHPMR ALFLIPRNPP PRLKSKKWSK KFFSFIEGCL VKNYMQRPST EQLLKHPFIR DQPNERQVRI QLKDHIDRTR KKRGEKDETE YEYSGSEEEE EEVPEQEGEP SSIVNVPGES TLRRDFLRLQ QENKERSEAL RRQQLLQEQQ LREQEEYKRQ LLAERQKRIE QQKEQRRRLE EQQRREREAR RQQEREQRRR EQEEKRRLEE LERRRKEEEE RRRAEEEKRR VEREQEYIRR QLEEEQRHLE VLQQQLLQEQ AMLLHDHRRP HPQHSQQPPP PQQERSKPSF HAPEPKAHYE PADRAREVED RFRKTNHSSP EAQSKQTGRV LEPPVPSRSE SFSNGNSESV HPALQRPAEP QVPVRTTSRS PVLSRRDSPL QGSGQQNSQA GQRNSTSSIE PRLLWERVEK LVPRPGSGSS SGSSNSGSQP GSHPGSQSGS GERFRVRSSS KSEGSPSQRL ENAVKKPEDK KEVFRPLKPA GEVDLTALAK ELRAVEDVRP PHKVTDYSSS SEESGTTDEE DDDVEQEGAD ESTSGPEDTR AASSLNLSNG ETESVKTMIV HDDVESEPAM TPSKEGTLIV RQTQSASSTL QKHKSSSSFT PFIDPRLLQI SPSSGTTVTS VVGFSCDGMR PEAIRQDPTR KGSVVNVNPT NTRPQSDTPE IRKYKKRFNS EILCAALWGV NLLVGTESGL MLLDRSGQGK VYPLINRRRF QQMDVLEGLN VLVTISGKKD KLRVYYLSWL RNKILHNDPE VEKKQGWTTV GDLEGCVHYK VVKYERIKFL VIALKSSVEV YAWAPKPYHK FMAFKSFGEL VHKPLLVDLT VEEGQRLKVI YGSCAGFHAV DVDSGSVYDI YLPTHIQCSI KPHAIIILPN TDGMELLVCY EDEGVYVNTY GRITKDVVLQ WGEMPTSVAY IRSNQTMGWG EKAIEIRSVE TGHLDGVFMH KRAQRLKFLC ERNDKVFFAS VRSGGSSQVY FMTLGRTSLL SW
Genular Protein ID: 1087470664
Symbol: B7Z3V5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 1235
- Mass: 141098
- Checksum: D486AACD86467302
- Sequence:
MANDSPAKSL VDIDLSSLRD PAGIFELVEV VGNGTYGQVY KGRHVKTGQL AAIKVMDVTE DEEEEIKLEI NMLKKYSHHR NIATYYGAFI KKSPPGHDDQ LWLVMEFCGA GSITDLVKNT KGNTLKEDWI AYISREILRG LAHLHIHHVI HRDIKGQNVL LTENAEVKLV DFGVSAQLDR TVGRRNTFIG TPYWMAPEVI ACDENPDATY DYRSDLWSCG ITAIEMAEGA PPLCDMHPMR ALFLIPRNPP PRLKSKKWSK KFFSFIEGCL VKNYMQRPST EQLLKHPFIR DQPNERQVRI QLKDHIDRTR KKRGEKDETE YEYSGSEEEE EEVPEQEGEP SSIVNVPGES TLRRDFLRLQ QENKERSEAL RRQQLLQEQQ LREQEEYKRQ LLAERQKRIE QQKEQRRRLE EQQRREREAR RQQEREQRRR EQEEKRRLEE LERRRKEEEE RRRAEEEKRR VEREQEYIRR QLEEEQRHLE VLQQQLLQEQ AMLLHDHRRP HPQHSQQPPP PQQERSKPSF HAPEPKAHYE PADRAREVQW SHLASLKNNV SPVSRSHSFS DPSPKFAHHH LRSQDPCPPS RSEVLSQSSD SKSEAPDPTQ KAWSRSDSDE VPPRVPVRTT SRSPVLSRRD SPLQGSGQQN SQAGQRNSTS SIEPRLLWER VEKLVPRPGS GSSSGSSNSG SQPGSHPGSQ SGSGERFRVR SSSKSEGSPS QRLENAVKKP EDKKEVFRPL KPAGEVDLTA LAKELRAVED VRPPHKVTDY SSSSEESGTT DEEDDDVEQE GADESTSGPE DTRAASSLNL SNGETESVKT MIVHDDVESE PAMTPSKEGT LIVRQTQSAS STLQKHKSSS SFTPFIDPRL LQISPSSGTT VTSMVGFSCD GMRPEAIRQD PTRKGSVVNV NPTNTRPQSD TPEIRKYKKR FNSEILCAAL WGVNLLVGTE SGLMLLDRSG QGKVYPLINR RRFQQMDVLE GLNVLVTISG KKDKLRVYYL SWLRNKILHN DPEVEKKQGW TTVGDLEGCV HYKVVKYERI KFLVIALKSS VEVYAWAPKP YHKFMAFKSF GELVHKPLLV DLTVEEGQRL KVIYGSCAGF HAVDVDSGSV YDIYLPTHIQ CSIKPHAIII LPNTDGMELL VCYEDEGVYV NTYGRITKDV VLQWGEMPTS VAYIRSNQTM GWGEKAIEIR SVETGHLDGV FMHKRAQRLK FLCERNDKVF FASVRSGGSS QVYFMTLGRT SLLSW
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.