Associated with
Other Information
Genular Protein ID: 19429687
Symbol: CD33_HUMAN
Name: Myeloid cell surface antigen CD33
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3139766
Title: Isolation of a cDNA encoding CD33, a differentiation antigen of myeloid progenitor cells.
PubMed ID: 3139766
PubMed ID: 11943481
Title: Genomic organization of the siglec gene locus on chromosome 19q13.4 and cloning of two new siglec pseudogenes.
PubMed ID: 11943481
PubMed ID: 16380601
Title: A study of CD33 (SIGLEC-3) antigen expression and function on activated human T and NK cells: two isoforms of CD33 are generated by alternative splicing.
PubMed ID: 16380601
DOI: 10.1189/jlb.0205096
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7718872
Title: Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules.
PubMed ID: 7718872
PubMed ID: 8702538
Title: A single N-linked glycosylation site is implicated in the regulation of ligand recognition by the I-type lectins CD22 and CD33.
PubMed ID: 8702538
PubMed ID: 10556798
Title: The sialoadhesin CD33 is a myeloid-specific inhibitory receptor.
PubMed ID: 10556798
DOI: 10.1002/(sici)1521-4141(199911)29:11<3440::aid-immu3440>3.0.co;2-c
PubMed ID: 10206955
Title: The myeloid-specific sialic acid-binding receptor, CD33, associates with the protein-tyrosine phosphatases, SHP-1 and SHP-2.
PubMed ID: 10206955
PubMed ID: 10611343
Title: Engagement of p75/AIRM1 or CD33 inhibits the proliferation of normal or leukemic myeloid cells.
PubMed ID: 10611343
PubMed ID: 10887109
Title: Myeloid specific human CD33 is an inhibitory receptor with differential ITIM function in recruiting the phosphatases SHP-1 and SHP-2.
PubMed ID: 10887109
PubMed ID: 11320212
Title: Surface expression and function of p75/AIRM-1 or CD33 in acute myeloid leukemias: engagement of CD33 induces apoptosis of leukemic cells.
PubMed ID: 11320212
PubMed ID: 15597323
Title: Constitutive repressor activity of CD33 on human monocytes requires sialic acid recognition and phosphoinositide 3-kinase-mediated intracellular signaling.
PubMed ID: 15597323
PubMed ID: 28325905
Title: Evidence for C1q-mediated crosslinking of CD33/LAIR-1 inhibitory immunoreceptors and biological control of CD33/LAIR-1 expression.
PubMed ID: 28325905
PubMed ID: 28747436
Title: The Alzheimer's disease-protective CD33 splice variant mediates adaptive loss of function via diversion to an intracellular pool.
PubMed ID: 28747436
Sequence Information:
- Length: 364
- Mass: 39825
- Checksum: 1C73E588240FBAD8
- Sequence:
MPLLLLLPLL WAGALAMDPN FWLQVQESVT VQEGLCVLVP CTFFHPIPYY DKNSPVHGYW FREGAIISRD SPVATNKLDQ EVQEETQGRF RLLGDPSRNN CSLSIVDARR RDNGSYFFRM ERGSTKYSYK SPQLSVHVTD LTHRPKILIP GTLEPGHSKN LTCSVSWACE QGTPPIFSWL SAAPTSLGPR TTHSSVLIIT PRPQDHGTNL TCQVKFAGAG VTTERTIQLN VTYVPQNPTT GIFPGDGSGK QETRAGVVHG AIGGAGVTAL LALCLCLIFF IVKTHRRKAA RTAVGRNDTH PTTGSASPKH QKKSKLHGPT ETSSCSGAAP TVEMDEELHY ASLNFHGMNP SKDTSTEYSE VRTQ
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.