Details for: ARHGEF6

Gene ID: 9459

Symbol: ARHGEF6

Ensembl ID: ENSG00000129675

Description: Rac/Cdc42 guanine nucleotide exchange factor 6

Associated with

Other Information

Genular Protein ID: 791676782

Symbol: ARHG6_HUMAN

Name: Rho guanine nucleotide exchange factor 6

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11017088

Title: Mutations in ARHGEF6, encoding a guanine nucleotide exchange factor for Rho GTPases, in patients with X-linked mental retardation.

PubMed ID: 11017088

DOI: 10.1038/80002

PubMed ID: 7584026

Title: Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1.

PubMed ID: 7584026

DOI: 10.1093/dnares/1.1.27

PubMed ID: 11337747

Title: Characterization of ARHGEF6, a guanine nucleotide exchange factor for Rho GTPases and a candidate gene for X-linked mental retardation: mutation screening in Borjeson-Forssman-Lehmann syndrome and MRX27.

PubMed ID: 11337747

DOI: 10.1002/ajmg.1189

PubMed ID: 15144186

Title: Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.

PubMed ID: 15144186

DOI: 10.1021/ac035352d

PubMed ID: 15005707

Title: The first CH domain of affixin activates Cdc42 and Rac1 through alphaPIX, a Cdc42/Rac1-specific guanine nucleotide exchanging factor.

PubMed ID: 15005707

DOI: 10.1111/j.1356-9597.2004.00717.x

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 23285027

Title: Bin2 is a membrane sculpting N-BAR protein that influences leucocyte podosomes, motility and phagocytosis.

PubMed ID: 23285027

DOI: 10.1371/journal.pone.0052401

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 776
  • Mass: 87499
  • Checksum: 5D2622314E46341B
  • Sequence:
  • MNPEEQIVTW LISLGVLESP KKTICDPEEF LKSSLKNGVV LCKLINRLMP GSVEKFCLDP 
    QTEADCINNI NDFLKGCATL QVEIFDPDDL YSGVNFSKVL STLLAVNKAT EDQLSERPCG 
    RSSSLSAANT SQTNPQGAVS STVSGLQRQS KTVEMTENGS HQLIVKARFN FKQTNEDELS 
    VCKGDIIYVT RVEEGGWWEG TLNGRTGWFP SNYVREIKSS ERPLSPKAVK GFETAPLTKN 
    YYTVVLQNIL DTEKEYAKEL QSLLVTYLRP LQSNNNLSTV EVTSLLGNFE EVCTFQQTLC 
    QALEECSKFP ENQHKVGGCL LSLMPHFKSM YLAYCANHPS AVNVLTQHSD ELEQFMENQG 
    ASSPGILILT TNLSKPFMRL EKYVTLLQEL ERHMEDTHPD HQDILKAIVA FKTLMGQCQD 
    LRKRKQLELQ ILSEPIQAWE GEDIKNLGNV IFMSQVMVQY GACEEKEERY LMLFSNVLIM 
    LSASPRMSGF IYQGKIPIAG TVVTRLDEIE GNDCTFEITG NTVERIVVHC NNNQDFQEWL 
    EQLNRLIRGP ASCSSLSKTS SSSCSAHSSF SSTGQPRGPL EPPQIIKPWS LSCLRPAPPL 
    RPSAALGYKE RMSYILKESS KSPKTMKKFL HKRKTERKPS EEEYVIRKST AALEEDAQIL 
    KVIEAYCTSA NFQQGHGSST RKDSIPQVLL PEEEKLIIEE TRSNGQTIME EKSLVDTVYA 
    LKDEVRELKQ ENKRMKQCLE EELKSRRDLE KLVRRLLKQT DECIRGESSS KTSILP

Genular Protein ID: 3768072540

Symbol: Q8N4Q3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 320
  • Mass: 36201
  • Checksum: 8444098AD0C0ECEE
  • Sequence:
  • HASDGACEEK EERYLMLFSN VLIMLSASPR MSGFIYQGKI PIAGTVVTRL DEIEGNDCTF 
    EITGNTVERI VVHCNNNQDF QEWLEQLNRL IRGPASCSSL SKTSSSSCSA HSSFSSTGQP 
    RGPLEPPQII KPWSLSCLRP APPLRPSAAL GYKERMSYIL KESSKSPKTM KKFLHKRKTE 
    RKPSEEEYVI RKSTAALEED AQILKVIEAY CTSANFQQGH GSSTRKDSIP QVLLPEEEKL 
    IIEETRSNGQ TIMEEKSLVD TVYALKDEVR ELKQENKRMK QCLEEELKSR RDLEKLVRRL 
    LKQTDECIRG ESSSKTSILP

Genular Protein ID: 3036510716

Symbol: B7Z3C7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 649
  • Mass: 73460
  • Checksum: 48C2C78045328090
  • Sequence:
  • MTENGSHQLI VKARFNFKQT NEDELSVCKG DIIYVTRVEE GGWWEGTLNG RTGWFPSNYV 
    REIKSSDGVS LLLPGLECNG AISAHHNLCL PGSKRPLSPK AVKGFETAPL TKNYYTVVLQ 
    NILDTEKEYA KELQSLLVTY LRPLQSNNNL STVEVTSLLG NFEEVCTFQQ TLCQALEECS 
    KFPENQHKVG GCLLSLMPHF KSMYLAYCAN HPSAVNVLTQ HSDELEQFME NQGASSPGIL 
    ILTTNLSKPF MRLEKYVTLL QELERHMEDT HPDHQDILKA IVAFKTLMGQ CQDLRKRKQL 
    ELQILSEPIQ AWEGEDIKNL GNVIFMSQVM VQYGACEEKE ERYLMLFSNV LIMLSASPRM 
    SGFIYQGKIP IAGTVVTRLD EIEGNDCTFE ITGNTVERIV VHCNNNQDFQ EWLEQLNRLI 
    RGPASCSSLS KTSSSSCSAH SSFSSTGQPR GPLEPPQIIK PWSLSCLRPA PPLRPSAALG 
    YKERMSYILK ESSKSPKTMK KFLHKRKTER KPSEEEYVIR KSTAALEEDA QILKVIEAYC 
    TSANFQQGHG SSTRKDSIPQ VLLPEEEKLI IEETRSNGQT IMEEKSLVDT VYALKDEVRE 
    LKQENKRMKQ CLEEELKSRR DLEKLVRRLL KQTDECIRGE SSSKTSILP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.