Details for: ARHGEF6

Gene ID: 9459

Symbol: ARHGEF6

Ensembl ID: ENSG00000129675

Description: Rac/Cdc42 guanine nucleotide exchange factor 6

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.93
    Marker Score: 1,927
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 1.84
    Marker Score: 913
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 1.66
    Marker Score: 2,073
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.56
    Marker Score: 33,197
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.54
    Marker Score: 1,118
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.47
    Marker Score: 716
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.46
    Marker Score: 168,018
  • Cell Name: basophil (CL0000767)
    Fold Change: 1.41
    Marker Score: 668
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.39
    Marker Score: 1,279
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 1.24
    Marker Score: 447
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 1.23
    Marker Score: 27,385
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 1.2
    Marker Score: 1,696
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.14
    Marker Score: 988
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.13
    Marker Score: 4,726
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 1.1
    Marker Score: 1,267
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.1
    Marker Score: 67,549
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.09
    Marker Score: 16,978
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.06
    Marker Score: 39,022
  • Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
    Fold Change: 1.06
    Marker Score: 765
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 1.05
    Marker Score: 4,068
  • Cell Name: blood cell (CL0000081)
    Fold Change: 1.05
    Marker Score: 12,173
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 1.04
    Marker Score: 450
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.04
    Marker Score: 10,539
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.01
    Marker Score: 589
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 1.01
    Marker Score: 1,977
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: 1
    Marker Score: 2,824
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1
    Marker Score: 6,379
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,715
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47,940
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: 1
    Marker Score: 678
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,396
  • Cell Name: Unknown (CL0000548)
    Fold Change: 0.96
    Marker Score: 696
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 0.95
    Marker Score: 2,379
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 0.95
    Marker Score: 1,464
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,402
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 0.94
    Marker Score: 594
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.94
    Marker Score: 388
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 0.94
    Marker Score: 2,584
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.94
    Marker Score: 482
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 0.93
    Marker Score: 13,932
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.93
    Marker Score: 438
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.93
    Marker Score: 932
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 0.92
    Marker Score: 3,278
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,713
  • Cell Name: double negative T regulatory cell (CL0011024)
    Fold Change: 0.9
    Marker Score: 871
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: 0.9
    Marker Score: 788
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.89
    Marker Score: 356
  • Cell Name: hematopoietic precursor cell (CL0008001)
    Fold Change: 0.88
    Marker Score: 309
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.88
    Marker Score: 9,060
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.87
    Marker Score: 401
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.87
    Marker Score: 48,640
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,246
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.86
    Marker Score: 310
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.86
    Marker Score: 4,905
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 0.86
    Marker Score: 45,306
  • Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
    Fold Change: 0.85
    Marker Score: 2,075
  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 0.85
    Marker Score: 2,311
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: 0.85
    Marker Score: 2,194
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 0.84
    Marker Score: 799
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.84
    Marker Score: 502
  • Cell Name: granulocyte (CL0000094)
    Fold Change: 0.83
    Marker Score: 373
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 0.83
    Marker Score: 545
  • Cell Name: mast cell (CL0000097)
    Fold Change: 0.83
    Marker Score: 479
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 0.81
    Marker Score: 440
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 0.8
    Marker Score: 7,934
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 0.8
    Marker Score: 2,526
  • Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
    Fold Change: 0.8
    Marker Score: 584
  • Cell Name: dendritic cell, human (CL0001056)
    Fold Change: 0.79
    Marker Score: 809
  • Cell Name: fat cell (CL0000136)
    Fold Change: 0.79
    Marker Score: 440
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 0.78
    Marker Score: 3,331
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.77
    Marker Score: 592
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: 0.77
    Marker Score: 1,380
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 0.77
    Marker Score: 953
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.77
    Marker Score: 1,690
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 0.76
    Marker Score: 1,468
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.76
    Marker Score: 1,236
  • Cell Name: late pro-B cell (CL0002048)
    Fold Change: 0.76
    Marker Score: 897
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 0.76
    Marker Score: 190
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: 0.76
    Marker Score: 672
  • Cell Name: erythroid progenitor cell, mammalian (CL0001066)
    Fold Change: 0.75
    Marker Score: 240
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 0.75
    Marker Score: 801
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 0.75
    Marker Score: 273
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.74
    Marker Score: 239
  • Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
    Fold Change: 0.74
    Marker Score: 453
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 0.73
    Marker Score: 575
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.73
    Marker Score: 376
  • Cell Name: small pre-B-II cell (CL0000954)
    Fold Change: 0.72
    Marker Score: 863
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 0.71
    Marker Score: 1,378
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.7
    Marker Score: 642
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 0.7
    Marker Score: 700
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 0.69
    Marker Score: 384
  • Cell Name: kidney collecting duct cell (CL1001225)
    Fold Change: 0.68
    Marker Score: 134
  • Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
    Fold Change: 0.68
    Marker Score: 558
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 0.68
    Marker Score: 340
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: 0.68
    Marker Score: 996
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.68
    Marker Score: 173
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 0.67
    Marker Score: 650
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 0.67
    Marker Score: 1,225
  • Cell Name: common dendritic progenitor (CL0001029)
    Fold Change: 0.67
    Marker Score: 232
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 0.67
    Marker Score: 280

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ARHGEF6 is a highly conserved protein that belongs to the Rho GEF family. It is composed of three main domains: an NH2-terminal helix, a central Dbl-homology domain, and a C-terminal pleckstrin homology domain. The Dbl-homology domain is responsible for binding to GTP-bound Rac and Cdc42, while the pleckstrin homology domain interacts with phospholipids to facilitate the exchange of GDP for GTP. ARHGEF6 is predominantly expressed in enterocytes, macrophages, neurons, and goblet cells, suggesting its involvement in various cellular processes, including immune responses, neurodegenerative diseases, and gastrointestinal disorders. **Pathways and Functions:** ARHGEF6 is involved in multiple signaling pathways, including: 1. **Rac/Cdc42 GTPase cycle:** ARHGEF6 activates Rac and Cdc42 GTPases, which regulate the actin cytoskeleton, cell migration, and cell death signaling. 2. **Cell-cell communication:** ARHGEF6 modulates the signaling pathways involved in cell-cell communication, including the JNK cascade and the NTR receptor-mediated signaling. 3. **Cytoskeletal remodeling:** ARHGEF6 regulates the cytoskeletal remodeling process, which is essential for cell migration, proliferation, and apoptosis. 4. **Death receptor signaling:** ARHGEF6 interacts with death receptors, such as P75NTR, to regulate cell death signaling pathways. **Clinical Significance:** Dysregulation of ARHGEF6 has been implicated in various diseases, including: 1. **Neurodegenerative disorders:** ARHGEF6 has been linked to Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS), where it regulates the signaling pathways involved in neurodegeneration. 2. **Gastrointestinal disorders:** ARHGEF6 is involved in the regulation of gut motility and secretion, making it a potential target for treating gastrointestinal disorders, such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). 3. **Cancer:** ARHGEF6 has been implicated in cancer progression, where it regulates cell migration, invasion, and metastasis. 4. **Immune disorders:** ARHGEF6 is involved in the regulation of immune responses, making it a potential target for treating autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. In conclusion, ARHGEF6 is a complex gene that plays a crucial role in regulating various cellular processes, including cell-cell communication, cytoskeletal remodeling, and death receptor signaling. Its dysregulation has been implicated in various diseases, making it a potential target for therapeutic intervention. Further research is needed to fully elucidate the mechanisms underlying ARHGEF6-mediated signaling pathways and to explore its potential as a therapeutic target.

Genular Protein ID: 791676782

Symbol: ARHG6_HUMAN

Name: Rho guanine nucleotide exchange factor 6

UniProtKB Accession Codes:

Q15052 A6NMW9 A8K6S7 B1AL37 Q15396 Q5JQ66 Q7Z3W1 Q86XH0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 4 CORUM 1 CPTAC 2 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 12 EPD 1 Ensembl 3 EvolutionaryTrace 1 GO 9 Gene3D 5 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 12 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 2 PRINTS 2 PRO 1 PROSITE 4 PROSITE-ProRule 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 7 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 7 RefSeq 2 SAM 1 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 4 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11017088

Title: Mutations in ARHGEF6, encoding a guanine nucleotide exchange factor for Rho GTPases, in patients with X-linked mental retardation.

PubMed ID: 11017088

DOI: 10.1038/80002

PubMed ID: 7584026

Title: Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1.

PubMed ID: 7584026

DOI: 10.1093/dnares/1.1.27

PubMed ID: 11337747

Title: Characterization of ARHGEF6, a guanine nucleotide exchange factor for Rho GTPases and a candidate gene for X-linked mental retardation: mutation screening in Borjeson-Forssman-Lehmann syndrome and MRX27.

PubMed ID: 11337747

DOI: 10.1002/ajmg.1189

PubMed ID: 15144186

Title: Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.

PubMed ID: 15144186

DOI: 10.1021/ac035352d

PubMed ID: 15005707

Title: The first CH domain of affixin activates Cdc42 and Rac1 through alphaPIX, a Cdc42/Rac1-specific guanine nucleotide exchanging factor.

PubMed ID: 15005707

DOI: 10.1111/j.1356-9597.2004.00717.x

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 23285027

Title: Bin2 is a membrane sculpting N-BAR protein that influences leucocyte podosomes, motility and phagocytosis.

PubMed ID: 23285027

DOI: 10.1371/journal.pone.0052401

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 776
  • Mass: 87499
  • Checksum: 5D2622314E46341B
  • Sequence:
    • MNPEEQIVTW LISLGVLESP KKTICDPEEF LKSSLKNGVV LCKLINRLMP GSVEKFCLDP 
QTEADCINNI NDFLKGCATL QVEIFDPDDL YSGVNFSKVL STLLAVNKAT EDQLSERPCG 
RSSSLSAANT SQTNPQGAVS STVSGLQRQS KTVEMTENGS HQLIVKARFN FKQTNEDELS 
VCKGDIIYVT RVEEGGWWEG TLNGRTGWFP SNYVREIKSS ERPLSPKAVK GFETAPLTKN 
YYTVVLQNIL DTEKEYAKEL QSLLVTYLRP LQSNNNLSTV EVTSLLGNFE EVCTFQQTLC 
QALEECSKFP ENQHKVGGCL LSLMPHFKSM YLAYCANHPS AVNVLTQHSD ELEQFMENQG 
ASSPGILILT TNLSKPFMRL EKYVTLLQEL ERHMEDTHPD HQDILKAIVA FKTLMGQCQD 
LRKRKQLELQ ILSEPIQAWE GEDIKNLGNV IFMSQVMVQY GACEEKEERY LMLFSNVLIM 
LSASPRMSGF IYQGKIPIAG TVVTRLDEIE GNDCTFEITG NTVERIVVHC NNNQDFQEWL 
EQLNRLIRGP ASCSSLSKTS SSSCSAHSSF SSTGQPRGPL EPPQIIKPWS LSCLRPAPPL 
RPSAALGYKE RMSYILKESS KSPKTMKKFL HKRKTERKPS EEEYVIRKST AALEEDAQIL 
KVIEAYCTSA NFQQGHGSST RKDSIPQVLL PEEEKLIIEE TRSNGQTIME EKSLVDTVYA 
LKDEVRELKQ ENKRMKQCLE EELKSRRDLE KLVRRLLKQT DECIRGESSS KTSILP

Genular Protein ID: 3768072540

Symbol: Q8N4Q3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8N4Q3

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 GO 1 Gene3D 2 Genevisible 1 GenomeRNAi 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 3 PharmGKB 1 RefSeq 2 SAM 2 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 320
  • Mass: 36201
  • Checksum: 8444098AD0C0ECEE
  • Sequence:
    • HASDGACEEK EERYLMLFSN VLIMLSASPR MSGFIYQGKI PIAGTVVTRL DEIEGNDCTF 
EITGNTVERI VVHCNNNQDF QEWLEQLNRL IRGPASCSSL SKTSSSSCSA HSSFSSTGQP 
RGPLEPPQII KPWSLSCLRP APPLRPSAAL GYKERMSYIL KESSKSPKTM KKFLHKRKTE 
RKPSEEEYVI RKSTAALEED AQILKVIEAY CTSANFQQGH GSSTRKDSIP QVLLPEEEKL 
IIEETRSNGQ TIMEEKSLVD TVYALKDEVR ELKQENKRMK QCLEEELKSR RDLEKLVRRL 
LKQTDECIRG ESSSKTSILP

Genular Protein ID: 3036510716

Symbol: B7Z3C7_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z3C7

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 DNASU 1 EMBL 2 GO 2 Gene3D 4 GenomeRNAi 1 InterPro 9 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 6 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 5 ProteomicsDB 1 RefSeq 2 SAM 2 SMART 3 SUPFAM 3

Sequence Information:

  • Length: 649
  • Mass: 73460
  • Checksum: 48C2C78045328090
  • Sequence:
    • MTENGSHQLI VKARFNFKQT NEDELSVCKG DIIYVTRVEE GGWWEGTLNG RTGWFPSNYV 
REIKSSDGVS LLLPGLECNG AISAHHNLCL PGSKRPLSPK AVKGFETAPL TKNYYTVVLQ 
NILDTEKEYA KELQSLLVTY LRPLQSNNNL STVEVTSLLG NFEEVCTFQQ TLCQALEECS 
KFPENQHKVG GCLLSLMPHF KSMYLAYCAN HPSAVNVLTQ HSDELEQFME NQGASSPGIL 
ILTTNLSKPF MRLEKYVTLL QELERHMEDT HPDHQDILKA IVAFKTLMGQ CQDLRKRKQL 
ELQILSEPIQ AWEGEDIKNL GNVIFMSQVM VQYGACEEKE ERYLMLFSNV LIMLSASPRM 
SGFIYQGKIP IAGTVVTRLD EIEGNDCTFE ITGNTVERIV VHCNNNQDFQ EWLEQLNRLI 
RGPASCSSLS KTSSSSCSAH SSFSSTGQPR GPLEPPQIIK PWSLSCLRPA PPLRPSAALG 
YKERMSYILK ESSKSPKTMK KFLHKRKTER KPSEEEYVIR KSTAALEEDA QILKVIEAYC 
TSANFQQGHG SSTRKDSIPQ VLLPEEEKLI IEETRSNGQT IMEEKSLVDT VYALKDEVRE 
LKQENKRMKQ CLEEELKSRR DLEKLVRRLL KQTDECIRGE SSSKTSILP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.