PICK1 | ENSG00000100151 | NCBI 9463

Details for: PICK1

Gene ID: 9463

Symbol: PICK1

Ensembl ID: ENSG00000100151

Description: protein interacting with PRKCA 1

Associated with

Cell surface interactions at the vascular wall
(R-HSA-202733)
Glutamate binding, activation of ampa receptors and synaptic plasticity
(R-HSA-399721)
Hemostasis
(R-HSA-109582)
Neuronal system
(R-HSA-112316)
Neurotransmitter receptors and postsynaptic signal transmission
(R-HSA-112314)
Trafficking of ampa receptors
(R-HSA-399719)
Trafficking of glur2-containing ampa receptors
(R-HSA-416993)
Transmission across chemical synapses
(R-HSA-112315)
Actin filament binding
(GO:0051015)
Arp2/3 complex binding
(GO:0071933)
Cellular response to decreased oxygen levels
(GO:0036294)
Cellular response to glucose starvation
(GO:0042149)
Cytoplasm
(GO:0005737)
Cytoskeleton
(GO:0005856)
Cytosol
(GO:0005829)
Dendritic spine maintenance
(GO:0097062)
Dendritic spine organization
(GO:0097061)
Endocytic vesicle membrane
(GO:0030666)
Genomic imprinting
(GO:0071514)
Glial cell development
(GO:0021782)
Golgi apparatus
(GO:0005794)
G protein-coupled receptor binding
(GO:0001664)
Identical protein binding
(GO:0042802)
Intracellular protein transport
(GO:0006886)
Long-term synaptic depression
(GO:0060292)
Membrane curvature sensor activity
(GO:0140090)
Metal ion binding
(GO:0046872)
Monoamine transport
(GO:0015844)
Negative regulation of arp2/3 complex-mediated actin nucleation
(GO:0034316)
Neuronal ion channel clustering
(GO:0045161)
Neuron projection
(GO:0043005)
Perinuclear region of cytoplasm
(GO:0048471)
Phospholipid binding
(GO:0005543)
Plasma membrane
(GO:0005886)
Positive regulation of receptor internalization
(GO:0002092)
Post-fertilization epigenetic regulation of gene expression
(GO:0043045)
Postsynaptic density
(GO:0014069)
Postsynaptic early endosome
(GO:0098842)
Presynaptic membrane
(GO:0042734)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Protein kinase c-activating g protein-coupled receptor signaling pathway
(GO:0007205)
Protein kinase c binding
(GO:0005080)
Protein phosphorylation
(GO:0006468)
Receptor clustering
(GO:0043113)
Regulation of arp2/3 complex-mediated actin nucleation
(GO:0034315)
Regulation of insulin secretion
(GO:0050796)
Retrograde vesicle-mediated transport, golgi to endoplasmic reticulum
(GO:0006890)
Signaling receptor binding
(GO:0005102)
Synapse
(GO:0045202)
Synaptic vesicle
(GO:0008021)
Trans-golgi network membrane
(GO:0032588)

Other Information

Proteins

PRKCA-binding protein

Genular Protein ID: 1274914623

Symbol: PICK1_HUMAN

Name: PRKCA-binding protein

UniProtKB Accession Codes:

Q9NRD5 B3KS52 O95906

Database IDs:

Citations:

PubMed ID: 10623590

Title: Interaction of the PDZ domain of human PICK1 with class I ADP-ribosylation factors.

PubMed ID: 10623590

DOI: 10.1006/bbrc.1999.1932

PubMed ID: 12529303

Title: Reevaluating human gene annotation: a second-generation analysis of chromosome 22.

PubMed ID: 12529303

DOI: 10.1101/gr.695703

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11641419

Title: The carboxyl terminus of the prolactin-releasing peptide receptor interacts with PDZ domain proteins involved in alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor clustering.

PubMed ID: 11641419

DOI: 10.1124/mol.60.5.916

PubMed ID: 11343649

Title: Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1.

PubMed ID: 11343649

DOI: 10.1016/s0896-6273(01)00267-7

PubMed ID: 11802773

Title: Interaction of the synaptic protein PICK1 (protein interacting with C kinase 1) with the non-voltage gated sodium channels BNC1 (brain Na+ channel 1) and ASIC (acid-sensing ion channel).

PubMed ID: 11802773

DOI: 10.1042/0264-6021:3610443

PubMed ID: 15304526

Title: A role for the PDZ-binding domain of the coxsackie B virus and adenovirus receptor (CAR) in cell adhesion and growth.

PubMed ID: 15304526

DOI: 10.1242/jcs.01300

PubMed ID: 15247289

Title: The PDZ domain of PICK1 differentially accepts protein kinase C-alpha and GluR2 as interacting ligands.

PubMed ID: 15247289

DOI: 10.1074/jbc.m404499200

PubMed ID: 20403402

Title: Threonine 82 at the PDZ domain of PICK1 is critical for AMPA receptor interaction and localization.

PubMed ID: 20403402

DOI: 10.1016/j.neuint.2010.04.006

PubMed ID: 17384233

Title: Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.

PubMed ID: 17384233

DOI: 10.1110/ps.062657507

Sequence Information:

Length: 415
Mass: 46600
Checksum: C569FD8AA5028B90
Sequence:

MFADLDYDIE EDKLGIPTVP GKVTLQKDAQ NLIGISIGGG AQYCPCLYIV QVFDNTPAAL 
DGTVAAGDEI TGVNGRSIKG KTKVEVAKMI QEVKGEVTIH YNKLQADPKQ GMSLDIVLKK 
VKHRLVENMS SGTADALGLS RAILCNDGLV KRLEELERTA ELYKGMTEHT KNLLRAFYEL 
SQTHRAFGDV FSVIGVREPQ PAASEAFVKF ADAHRSIEKF GIRLLKTIKP MLTDLNTYLN 
KAIPDTRLTI KKYLDVKFEY LSYCLKVKEM DDEEYSCIAL GEPLYRVSTG NYEYRLILRC 
RQEARARFSQ MRKDVLEKME LLDQKHVQDI VFQLQRLVST MSKYYNDCYA VLRDADVFPI 
EVDLAHTTLA YGLNQEEFTD GEEEEEEEDT AAGEPSRDTR GAAGPLDKGG SWCDS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: PICK1

Associated with

Other Information

Interaction of the PDZ domain of human PICK1 with class I ADP-ribosylation factors. PubMed ID: 10623590

Reevaluating human gene annotation: a second-generation analysis of chromosome 22. PubMed ID: 12529303

A genome annotation-driven approach to cloning the human ORFeome. PubMed ID: 15461802

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence of human chromosome 22. PubMed ID: 10591208

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The carboxyl terminus of the prolactin-releasing peptide receptor interacts with PDZ domain proteins involved in alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor clustering. PubMed ID: 11641419

Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1. PubMed ID: 11343649

Interaction of the synaptic protein PICK1 (protein interacting with C kinase 1) with the non-voltage gated sodium channels BNC1 (brain Na+ channel 1) and ASIC (acid-sensing ion channel). PubMed ID: 11802773

A role for the PDZ-binding domain of the coxsackie B virus and adenovirus receptor (CAR) in cell adhesion and growth. PubMed ID: 15304526

The PDZ domain of PICK1 differentially accepts protein kinase C-alpha and GluR2 as interacting ligands. PubMed ID: 15247289

Threonine 82 at the PDZ domain of PICK1 is critical for AMPA receptor interaction and localization. PubMed ID: 20403402

Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions. PubMed ID: 17384233