Details for: ATG5

Gene ID: 9474

Symbol: ATG5

Ensembl ID: ENSG00000057663

Description: autophagy related 5

Associated with

Other Information

Genular Protein ID: 62094808

Symbol: ATG5_HUMAN

Name: Autophagy protein 5

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9563500

Title: Homology between a human apoptosis specific protein and the product of APG5, a gene involved in autophagy in yeast.

PubMed ID: 9563500

DOI: 10.1016/s0014-5793(98)00266-x

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7796880

Title: A novel protein expressed in mammalian cells undergoing apoptosis.

PubMed ID: 7796880

DOI: 10.1006/excr.1995.1177

PubMed ID: 9852036

Title: A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy.

PubMed ID: 9852036

DOI: 10.1074/jbc.273.51.33889

PubMed ID: 11096062

Title: The human homolog of Saccharomyces cerevisiae Apg7p is a Protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3.

PubMed ID: 11096062

DOI: 10.1074/jbc.c000752200

PubMed ID: 11266458

Title: Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells.

PubMed ID: 11266458

DOI: 10.1083/jcb.152.4.657

PubMed ID: 12207896

Title: Mammalian Apg12p, but not the Apg12p.Apg5p conjugate, facilitates LC3 processing.

PubMed ID: 12207896

DOI: 10.1016/s0006-291x(02)02057-0

PubMed ID: 11825910

Title: Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p.

PubMed ID: 11825910

DOI: 10.1074/jbc.m200385200

PubMed ID: 15778222

Title: Essential roles of Atg5 and FADD in autophagic cell death: dissection of autophagic cell death into vacuole formation and cell death.

PubMed ID: 15778222

DOI: 10.1074/jbc.m413934200

PubMed ID: 15576571

Title: Escape of intracellular Shigella from autophagy.

PubMed ID: 15576571

DOI: 10.1126/science.1106036

PubMed ID: 16963840

Title: Stimulation of ATG12-ATG5 conjugation by ribonucleic acid.

PubMed ID: 16963840

DOI: 10.4161/auto.3270

PubMed ID: 17709747

Title: The Atg5-Atg12 conjugate associates with innate antiviral immune responses.

PubMed ID: 17709747

DOI: 10.1073/pnas.0704014104

PubMed ID: 19124466

Title: Regulation of autophagy by the p300 acetyltransferase.

PubMed ID: 19124466

DOI: 10.1074/jbc.m807135200

PubMed ID: 19666601

Title: The autophagy machinery is required to initiate hepatitis C virus replication.

PubMed ID: 19666601

DOI: 10.1073/pnas.0907344106

PubMed ID: 20580051

Title: Autophagy protein ATG5 interacts transiently with the hepatitis C virus RNA polymerase (NS5B) early during infection.

PubMed ID: 20580051

DOI: 10.1016/j.virol.2010.05.032

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21575909

Title: A Tecpr1-dependent selective autophagy pathway targets bacterial pathogens.

PubMed ID: 21575909

DOI: 10.1016/j.chom.2011.04.010

PubMed ID: 22170153

Title: Autophagy proteins LC3B, ATG5 and ATG12 participate in quality control after mitochondrial damage and influence lifespan.

PubMed ID: 22170153

DOI: 10.4161/auto.8.1.18174

PubMed ID: 22342342

Title: A mammalian autophagosome maturation mechanism mediated by TECPR1 and the Atg12-Atg5 conjugate.

PubMed ID: 22342342

DOI: 10.1016/j.molcel.2011.12.036

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23202584

Title: Structure of the human ATG12-ATG5 conjugate required for LC3 lipidation in autophagy.

PubMed ID: 23202584

DOI: 10.1038/nsmb.2431

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 26812546

Title: Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay.

PubMed ID: 26812546

DOI: 10.7554/elife.12245

Sequence Information:

  • Length: 275
  • Mass: 32447
  • Checksum: C33A1E0B3C1DBE5C
  • Sequence:
  • MTDDKDVLRD VWFGRIPTCF TLYQDEITER EAEPYYLLLP RVSYLTLVTD KVKKHFQKVM 
    RQEDISEIWF EYEGTPLKWH YPIGLLFDLL ASSSALPWNI TVHFKSFPEK DLLHCPSKDA 
    IEAHFMSCMK EADALKHKSQ VINEMQKKDH KQLWMGLQND RFDQFWAINR KLMEYPAEEN 
    GFRYIPFRIY QTTTERPFIQ KLFRPVAADG QLHTLGDLLK EVCPSAIDPE DGEKKNQVMI 
    HGIEPMLETP LQWLSEHLSY PDNFLHISII PQPTD

Genular Protein ID: 3279111580

Symbol: Q7Z3H3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

Sequence Information:

  • Length: 91
  • Mass: 10866
  • Checksum: 16AF577192AE011A
  • Sequence:
  • MTDDKDVLRD VWFGRIPTCF TLYQDEITER EAEPYYTDLT SFGPSIGNSW NILQKKMDFV 
    ISPLEYIRQR LKDLSFRSCF VLWLQMDSCT H

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.