Details for: MAPK8IP1

Gene ID: 9479

Symbol: MAPK8IP1

Ensembl ID: ENSG00000121653

Description: mitogen-activated protein kinase 8 interacting protein 1

Associated with

Other Information

Genular Protein ID: 4241917572

Symbol: JIP1_HUMAN

Name: C-Jun-amino-terminal kinase-interacting protein 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9933567

Title: Genomic organization, fine-mapping, and expression of the human islet-brain 1 (IB1)/C-jun-amino-terminal kinase interacting protein-1 (JIP-1) gene.

PubMed ID: 9933567

DOI: 10.1006/geno.1998.5641

PubMed ID: 10574993

Title: Interaction of c-Jun amino-terminal kinase interacting protein-1 with p190 rhoGEF and its localization in differentiated neurons.

PubMed ID: 10574993

DOI: 10.1074/jbc.274.49.35113

PubMed ID: 11238452

Title: Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules.

PubMed ID: 11238452

DOI: 10.1083/jcb.152.5.959

PubMed ID: 11726277

Title: Mixed lineage kinase LZK forms a functional signaling complex with JIP-1, a scaffold protein of the c-Jun NH(2)-terminal kinase pathway.

PubMed ID: 11726277

DOI: 10.1093/oxfordjournals.jbchem.a003048

PubMed ID: 11912189

Title: Interaction of Alzheimer's beta-amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade.

PubMed ID: 11912189

DOI: 10.1074/jbc.m108372200

PubMed ID: 12756254

Title: Recruitment of JNK to JIP1 and JNK-dependent JIP1 phosphorylation regulates JNK module dynamics and activation.

PubMed ID: 12756254

DOI: 10.1074/jbc.m304212200

PubMed ID: 11147798

Title: Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death.

PubMed ID: 11147798

DOI: 10.2337/diabetes.50.1.77

PubMed ID: 14507925

Title: Calcium- and proteasome-dependent degradation of the JNK scaffold protein islet-brain 1.

PubMed ID: 14507925

DOI: 10.1074/jbc.m306745200

PubMed ID: 12937412

Title: A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia.

PubMed ID: 12937412

DOI: 10.1038/nm911

PubMed ID: 16195223

Title: Hyperphosphorylation of JNK-interacting protein 1, a protein associated with Alzheimer disease.

PubMed ID: 16195223

DOI: 10.1074/mcp.m500226-mcp200

PubMed ID: 17709393

Title: Vaccinia-related kinase 2 modulates the stress response to hypoxia mediated by TAK1.

PubMed ID: 17709393

DOI: 10.1128/mcb.00025-07

PubMed ID: 18286207

Title: Modulation of interleukin-1 transcriptional response by the interaction between VRK2 and the JIP1 scaffold protein.

PubMed ID: 18286207

DOI: 10.1371/journal.pone.0001660

PubMed ID: 10700186

Title: The gene, MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes.

PubMed ID: 10700186

DOI: 10.1038/73523

Sequence Information:

  • Length: 711
  • Mass: 77524
  • Checksum: 55EA53B30080A751
  • Sequence:
  • MAERESGGLG GGAASPPAAS PFLGLHIASP PNFRLTHDIS LEEFEDEDLS EITDECGISL 
    QCKDTLSLRP PRAGLLSAGG GGAGSRLQAE MLQMDLIDAT GDTPGAEDDE EDDDEERAAR 
    RPGAGPPKAE SGQEPASRGQ GQSQGQSQGP GSGDTYRPKR PTTLNLFPQV PRSQDTLNNN 
    SLGKKHSWQD RVSRSSSPLK TGEQTPPHEH ICLSDELPPQ SGPAPTTDRG TSTDSPCRRS 
    TATQMAPPGG PPAAPPGGRG HSHRDRIHYQ ADVRLEATEE IYLTPVQRPP DAAEPTSAFL 
    PPTESRMSVS SDPDPAAYPS TAGRPHPSIS EEEEGFDCLS SPERAEPPGG GWRGSLGEPP 
    PPPRASLSSD TSALSYDSVK YTLVVDEHAQ LELVSLRPCF GDYSDESDSA TVYDNCASVS 
    SPYESAIGEE YEEAPRPQPP ACLSEDSTPD EPDVHFSKKF LNVFMSGRSR SSSAESFGLF 
    SCIINGEEQE QTHRAIFRFV PRHEDELELE VDDPLLVELQ AEDYWYEAYN MRTGARGVFP 
    AYYAIEVTKE PEHMAALAKN SDWVDQFRVK FLGSVQVPYH KGNDVLCAAM QKIATTRRLT 
    VHFNPPSSCV LEISVRGVKI GVKADDSQEA KGNKCSHFFQ LKNISFCGYH PKNNKYFGFI 
    TKHPADHRFA CHVFVSEDST KALAESVGRA FQQFYKQFVE YTCPTEDIYL E

Genular Protein ID: 4058748292

Symbol: Q6NUQ9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 711
  • Mass: 77468
  • Checksum: 4A5198DEB5E62381
  • Sequence:
  • MAERESGGLG GGAASPPAAS PFLGLHIASP PNFRLTHDIS LEEFEDEDLS EITDECGISL 
    QCKDTLSLRP PRAGLLSAGG GGAGSRLQAE MLQMDLIDAT GDTPGAEDDE EDDDEERAAR 
    RPGAGPPKAE SGQEPASRGQ GQSQGQSQGP GSGDTYRPKR PTTLNLFPQV PRSQDTLNNN 
    SLGKKHSWQD RVSRSSSPLK TGEQTPPHEH ICVSDELSPQ SGPAPTTGRG TSTDSPCRRS 
    TATQMAPPGG PPAATPGGRG HSHRDRIHYQ ADVRLEATEE IYLTPVQRPP DAAEPTSAFL 
    PPTESRMSVS SDPDPAAYPS TAGRPHPSIS EEEEGFDCMS SPERAEPPGG GWRGSLGEPP 
    PPPRASLSSD TSALSYDSVK YTLVVDEHAQ LELVSLRPCF GDYSDESDSA TVYDNCASVS 
    SPYESAIGEE YEEAPRPQPP ACLSEDSTPD EPDVHFSKKF LNVFMSGRSR SSSAESFGLF 
    SCIINGEEQE QTHRAIFRFV PRHEDELELE VDDPLLVELQ AEDYWYEAYN MRTGARGVFP 
    AYYAIEVTKE PEHMAALAKN SDWVDQFRVK FLGSVQVPYH KGNDVLCAAM QKIATTRRLT 
    VHFNPPSSCV LEINVRGVKI GVKADDSQEA KGNKCSHFFQ LKNISFCGYH PKNNKYFGFI 
    TKHPADNRFA CHVFVSEDST KALAESVGRA FQQFYKQFVE YTCPTEDIYL E

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.