Details for: ONECUT2

Gene ID: 9480

Symbol: ONECUT2

Ensembl ID: ENSG00000119547

Description: one cut homeobox 2

Associated with

  • Actin cytoskeleton
    (GO:0015629)
  • Animal organ morphogenesis
    (GO:0009887)
  • Cell fate commitment
    (GO:0045165)
  • Chromatin
    (GO:0000785)
  • Cilium assembly
    (GO:0060271)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Endocrine pancreas development
    (GO:0031018)
  • Epithelial cell development
    (GO:0002064)
  • Liver development
    (GO:0001889)
  • Mesenchymal stem cell migration
    (GO:1905319)
  • Negative regulation of transforming growth factor beta receptor signaling pathway
    (GO:0030512)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Peripheral nervous system neuron development
    (GO:0048935)
  • Positive regulation of mesenchymal stem cell migration
    (GO:1905322)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Regulation of cell-matrix adhesion
    (GO:0001952)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Transforming growth factor beta receptor signaling pathway
    (GO:0007179)

Other Information

Genular Protein ID: 4251094831

Symbol: ONEC2_HUMAN

Name: One cut domain family member 2

UniProtKB Accession Codes:

O95948

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 1 GO 22 Gene3D 2 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 2 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 1 SAM 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9915796

Title: OC-2, a novel mammalian member of the ONECUT class of homeodomain transcription factors whose function in liver partially overlaps with that of hepatocyte nuclear factor-6.

PubMed ID: 9915796

DOI: 10.1074/jbc.274.5.2665

PubMed ID: 16177791

Title: DNA sequence and analysis of human chromosome 18.

PubMed ID: 16177791

DOI: 10.1038/nature03983

Sequence Information:

  • Length: 504
  • Mass: 54303
  • Checksum: 09762F3C8BD6DD6B
  • Sequence:
    • MKAAYTAYRC LTKDLEGCAM NPELTMESLG TLHGPAGGGS GGGGGGGGGG GGGGPGHEQE 
LLASPSPHHA GRGAAGSLRG PPPPPTAHQE LGTAAAAAAA ASRSAMVTSM ASILDGGDYR 
PELSIPLHHA MSMSCDSSPP GMGMSNTYTT LTPLQPLPPI STVSDKFHHP HPHHHPHHHH 
HHHHQRLSGN VSGSFTLMRD ERGLPAMNNL YSPYKEMPGM SQSLSPLAAT PLGNGLGGLH 
NAQQSLPNYG PPGHDKMLSP NFDAHHTAML TRGEQHLSRG LGTPPAAMMS HLNGLHHPGH 
TQSHGPVLAP SRERPPSSSS GSQVATSGQL EEINTKEVAQ RITAELKRYS IPQAIFAQRV 
LCRSQGTLSD LLRNPKPWSK LKSGRETFRR MWKWLQEPEF QRMSALRLAA CKRKEQEPNK 
DRNNSQKKSR LVFTDLQRRT LFAIFKENKR PSKEMQITIS QQLGLELTTV SNFFMNARRR 
SLEKWQDDLS TGGSSSTSST CTKA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.