SLC25A27 | ENSG00000153291 | NCBI 9481

Details for: SLC25A27

Gene ID: 9481

Symbol: SLC25A27

Ensembl ID: ENSG00000153291

Description: solute carrier family 25 member 27

Associated with

Metabolism
(R-HSA-1430728)
Mitochondrial uncoupling
(R-HSA-166187)
Respiratory electron transport, atp synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
(R-HSA-163200)
The citric acid (tca) cycle and respiratory electron transport
(R-HSA-1428517)
The fatty acid cycling model
(R-HSA-167826)
The proton buffering model
(R-HSA-167827)
Apical part of cell
(GO:0045177)
Chloride transmembrane transport
(GO:1902476)
Chloride transmembrane transporter activity
(GO:0015108)
Inner ear development
(GO:0048839)
Intracellular triglyceride homeostasis
(GO:0035356)
Mitochondrial inner membrane
(GO:0005743)
Mitochondrial membrane
(GO:0031966)
Mitochondrion
(GO:0005739)
Negative regulation of mitochondrial calcium ion concentration
(GO:0051562)
Negative regulation of mitochondrial membrane potential
(GO:0010917)
Negative regulation of neuron apoptotic process
(GO:0043524)
Neuronal cell body
(GO:0043025)
Positive regulation of cell population proliferation
(GO:0008284)
Protein homodimerization activity
(GO:0042803)
Proton transmembrane transport
(GO:1902600)
Proton transmembrane transporter activity
(GO:0015078)
Regulation of glucose import
(GO:0046324)
Response to cold
(GO:0009409)
Transmembrane transporter activity
(GO:0022857)

Other Information

Proteins

Mitochondrial uncoupling protein 4
B4DHR4_HUMAN

Genular Protein ID: 2959388602

Symbol: UCP4_HUMAN

Name: Mitochondrial uncoupling protein 4

UniProtKB Accession Codes:

O95847 F5GWR4 Q5VTS9 Q8N518

Database IDs:

Citations:

PubMed ID: 10025957

Title: UCP4, a novel brain-specific mitochondrial protein that reduces membrane potential in mammalian cells.

PubMed ID: 10025957

DOI: 10.1016/s0014-5793(98)01713-x

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 22524567

Title: Toward understanding the mechanism of ion transport activity of neuronal uncoupling proteins UCP2, UCP4, and UCP5.

PubMed ID: 22524567

DOI: 10.1021/bi3003378

PubMed ID: 26182433

Title: A biophysical study on molecular physiology of the uncoupling proteins of the central nervous system.

PubMed ID: 26182433

DOI: 10.1042/bsr20150130

Sequence Information:

Length: 323
Mass: 36064
Checksum: 4C54A56BB10333ED
Sequence:

MSVPEEEERL LPLTQRWPRA SKFLLSGCAA TVAELATFPL DLTKTRLQMQ GEAALARLGD 
GARESAPYRG MVRTALGIIE EEGFLKLWQG VTPAIYRHVV YSGGRMVTYE HLREVVFGKS 
EDEHYPLWKS VIGGMMAGVI GQFLANPTDL VKVQMQMEGK RKLEGKPLRF RGVHHAFAKI 
LAEGGIRGLW AGWVPNIQRA ALVNMGDLTT YDTVKHYLVL NTPLEDNIMT HGLSSLCSGL 
VASILGTPAD VIKSRIMNQP RDKQGRGLLY KSSTDCLIQA VQGEGFMSLY KGFLPSWLRM 
TPWSMVFWLT YEKIREMSGV SPF

Genular Protein ID: 2313225948

Symbol: B4DHR4_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DHR4

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

Sequence Information:

Length: 300
Mass: 33290
Checksum: 3E6A069081100B27
Sequence:

MSVPEEEERL LPLTQRWPRA SKFLLSGCAA TVAELATFPL DLTKTRLQMQ GEAALARLGD 
GARESAPYRG MVRTALGIIE EEGFLKLWQG VTPAIYRHVV YSGGRMVTYE HLREVVFGKS 
EDEHYPLWKS VIGGMMAGVI GQFLANPTDL VKVQMQMEGK RKLEGKPLRF RGVHHAFAKI 
LAEGGIRGLW AGWVPNIQRA ALVNMGDLTT YDTVKHYLVL NTPLEDNIMT HGLSSLCSGL 
VASILGTPAD VIKSRIMNQP RDKQGRGLLY KSSTDCLIQA VQGEGFMSLY KGFLPSWLRM

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: SLC25A27

Associated with

Other Information

UCP4, a novel brain-specific mitochondrial protein that reduces membrane potential in mammalian cells. PubMed ID: 10025957

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. PubMed ID: 12975309

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and analysis of human chromosome 6. PubMed ID: 14574404

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Toward understanding the mechanism of ion transport activity of neuronal uncoupling proteins UCP2, UCP4, and UCP5. PubMed ID: 22524567

A biophysical study on molecular physiology of the uncoupling proteins of the central nervous system. PubMed ID: 26182433

The sequence of the human genome. PubMed ID: 11181995