AKAP5 | ENSG00000179841 | NCBI 9495

Details for: AKAP5

Gene ID: 9495

Symbol: AKAP5

Ensembl ID: ENSG00000179841

Description: A-kinase anchoring protein 5

Associated with

Axon guidance
(R-HSA-422475)
Developmental biology
(R-HSA-1266738)
Glucagon-like peptide-1 (glp1) regulates insulin secretion
(R-HSA-381676)
Glutamate binding, activation of ampa receptors and synaptic plasticity
(R-HSA-399721)
Integration of energy metabolism
(R-HSA-163685)
Metabolism
(R-HSA-1430728)
Nervous system development
(R-HSA-9675108)
Neuronal system
(R-HSA-112316)
Neurotransmitter receptors and postsynaptic signal transmission
(R-HSA-112314)
Regulation of insulin secretion
(R-HSA-422356)
Robo receptors bind akap5
(R-HSA-9010642)
Signaling by robo receptors
(R-HSA-376176)
Trafficking of ampa receptors
(R-HSA-399719)
Transmission across chemical synapses
(R-HSA-112315)
Adenylate cyclase-inhibiting g protein-coupled receptor signaling pathway
(GO:0007193)
Adenylate cyclase binding
(GO:0008179)
Beta-2 adrenergic receptor binding
(GO:0031698)
Calmodulin binding
(GO:0005516)
Chemical synaptic transmission
(GO:0007268)
Cytoplasmic side of plasma membrane
(GO:0009898)
Cytosol
(GO:0005829)
Dendrite membrane
(GO:0032590)
Dendritic spine
(GO:0043197)
Excitatory synapse
(GO:0060076)
Gaba receptor binding
(GO:0050811)
Glutamate receptor binding
(GO:0035254)
Membrane raft
(GO:0045121)
Molecular adaptor activity
(GO:0060090)
Negative regulation of adenylate cyclase activity
(GO:0007194)
Plasma membrane
(GO:0005886)
Positive regulation of calcineurin-nfat signaling cascade
(GO:0070886)
Positive regulation of calcium ion import across plasma membrane
(GO:1905665)
Positive regulation of endosome to plasma membrane protein transport
(GO:1905751)
Positive regulation of long-term synaptic potentiation
(GO:1900273)
Positive regulation of protein localization to plasma membrane
(GO:1903078)
Postsynaptic density
(GO:0014069)
Postsynaptic recycling endosome
(GO:0098837)
Postsynaptic recycling endosome membrane
(GO:0098944)
Protein binding
(GO:0005515)
Protein kinase a binding
(GO:0051018)
Protein kinase a regulatory subunit binding
(GO:0034237)
Protein phosphatase 2b binding
(GO:0030346)
Protein serine/threonine phosphatase complex
(GO:0008287)
Regulation of protein kinase a signaling
(GO:0010738)
Scaffold protein binding
(GO:0097110)
Sh3 domain binding
(GO:0017124)
Signal transduction
(GO:0007165)

Other Information

Proteins

A-kinase anchor protein 5
Q6PG46_HUMAN

Genular Protein ID: 1152919967

Symbol: AKAP5_HUMAN

Name: A-kinase anchor protein 5

UniProtKB Accession Codes:

P24588 A2RRB8

Database IDs:

Citations:

PubMed ID: 1512224

Title: Localization of the cAMP-dependent protein kinase to the postsynaptic densities by A-kinase anchoring proteins. Characterization of AKAP 79.

PubMed ID: 1512224

DOI: 10.1016/s0021-9258(18)41856-x

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12508121

Title: The DNA sequence and analysis of human chromosome 14.

PubMed ID: 12508121

DOI: 10.1038/nature01348

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1733921

Title: Cloning and expression of an intron-less gene for AKAP 75, an anchor protein for the regulatory subunit of cAMP-dependent protein kinase II beta.

PubMed ID: 1733921

DOI: 10.1016/s0021-9258(18)45852-8

PubMed ID: 21771783

Title: Palmitoylation targets AKAP79 protein to lipid rafts and promotes its regulation of calcium-sensitive adenylyl cyclase type 8.

PubMed ID: 21771783

DOI: 10.1074/jbc.m111.243899

PubMed ID: 25589740

Title: The palmitoyl acyltransferase DHHC2 regulates recycling endosome exocytosis and synaptic potentiation through palmitoylation of AKAP79/150.

PubMed ID: 25589740

DOI: 10.1523/jneurosci.2243-14.2015

Sequence Information:

Length: 427
Mass: 47088
Checksum: D2A86298EAF1BE32
Sequence:

METTISEIHV ENKDEKRSAE GSPGAERQKE KASMLCFKRR KKAAKALKPK AGSEAADVAR 
KCPQEAGASD QPEPTRGAWA SLKRLVTRRK RSESSKQQKP LEGEMQPAIN AEDADLSKKK 
AKSRLKIPCI KFPRGPKRSN HSKIIEDSDC SIKVQEEAEI LDIQTQTPLN DQATKAKSTQ 
DLSEGISRKD GDEVCESNVS NSTTSGEKVI SVELGLDNGH SAIQTGTLIL EEIETIKEKQ 
DVQPQQASPL ETSETDHQQP VLSDVPPLPA IPDQQIVEEA SNSTLESAPN GKDYESTEIV 
AEETKPKDTE LSQESDFKEN GITEEKSKSE ESKRMEPIAI IITDTEISEF DVTKSKNVPK 
QFLISAENEQ VGVFANDNGF EDRTSEQYET LLIETASSLV KNAIQLSIEQ LVNEMASDDN 
KINNLLQ

Genular Protein ID: 2257134

Symbol: Q6PG46_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6PG46

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 298
Mass: 32733
Checksum: A203A8B50975D3DC
Sequence:

METTISEIHV ENKDEKRSAE GSPGAERQKE KASMLCFKRR KKAAKALKPK AGSEAADVAR 
KCPQEAGASD QPEPTRGAWA SLKRLVTRRK RSESSKQQKP LEGEMQPAIN AEDADLSKKK 
AKSRLKIPCI KFPRGPKRSN HSKIIEDSDC SIKVQEEAEI LDIQTQTPLN DQATKAKSTQ 
DLSEGISRKD GDEVCESNVS NSITSGEKVI SVELGLDNGH SAIQTGTLIL EEIETIKEKQ 
DVQPQQASPL ETSETDHQQP VLSDVPPLPA IPDQQIVEEA SNSTLESAPK KKKKKKKK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: AKAP5

Associated with

Other Information

Localization of the cAMP-dependent protein kinase to the postsynaptic densities by A-kinase anchoring proteins. Characterization of AKAP 79. PubMed ID: 1512224

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and analysis of human chromosome 14. PubMed ID: 12508121

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Cloning and expression of an intron-less gene for AKAP 75, an anchor protein for the regulatory subunit of cAMP-dependent protein kinase II beta. PubMed ID: 1733921

Palmitoylation targets AKAP79 protein to lipid rafts and promotes its regulation of calcium-sensitive adenylyl cyclase type 8. PubMed ID: 21771783

The palmitoyl acyltransferase DHHC2 regulates recycling endosome exocytosis and synaptic potentiation through palmitoylation of AKAP79/150. PubMed ID: 25589740

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Database document:

PubMed ID: 1512224

PubMed ID: 14702039

PubMed ID: 12508121

PubMed ID: 15489334

PubMed ID: 1733921

PubMed ID: 21771783

PubMed ID: 25589740

PubMed ID: 15489334