Details for: SLC4A7

Gene ID: 9497

Symbol: SLC4A7

Ensembl ID: ENSG00000033867

Description: solute carrier family 4 member 7

Associated with

Other Information

Genular Protein ID: 1948473357

Symbol: S4A7_HUMAN

Name: Sodium bicarbonate cotransporter 3

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9610397

Title: Molecular cloning of a new sodium bicarbonate cotransporter cDNA from human retina.

PubMed ID: 9610397

DOI: 10.1006/bbrc.1998.8658

PubMed ID: 10347222

Title: Cloning, tissue distribution, genomic organization, and functional characterization of NBC3, a new member of the sodium bicarbonate cotransporter family.

PubMed ID: 10347222

DOI: 10.1074/jbc.274.23.16569

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 12403779

Title: The cystic fibrosis transmembrane conductance regulator interacts with and regulates the activity of the HCO3- salvage transporter human Na+-HCO3-cotransport isoform 3.

PubMed ID: 12403779

DOI: 10.1074/jbc.m201862200

PubMed ID: 12444018

Title: The COOH termini of NBC3 and the 56-kDa H+-ATPase subunit are PDZ motifs involved in their interaction.

PubMed ID: 12444018

DOI: 10.1152/ajpcell.00225.2002

PubMed ID: 14736710

Title: Regulation of the human NBC3 Na+/HCO3- cotransporter by carbonic anhydrase II and PKA.

PubMed ID: 14736710

DOI: 10.1152/ajpcell.00382.2003

PubMed ID: 15144186

Title: Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.

PubMed ID: 15144186

DOI: 10.1021/ac035352d

PubMed ID: 16301216

Title: Scaffold protein harmonin (USH1C) provides molecular links between Usher syndrome type 1 and type 2.

PubMed ID: 16301216

DOI: 10.1093/hmg/ddi417

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 14578046

Title: Structural and functional characterization of the human NBC3 sodium/bicarbonate co-transporter carboxyl-terminal cytoplasmic domain.

PubMed ID: 14578046

DOI: 10.1080/0968768031000122520

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19448079

Title: Modular structure of sodium-coupled bicarbonate transporters.

PubMed ID: 19448079

DOI: 10.1242/jeb.028563

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 29779931

Title: The Bicarbonate Transporter SLC4A7 Plays a Key Role in Macrophage Phagosome Acidification.

PubMed ID: 29779931

DOI: 10.1016/j.chom.2018.04.013

PubMed ID: 35772404

Title: The mTORC1-SLC4A7 axis stimulates bicarbonate import to enhance de novo nucleotide synthesis.

PubMed ID: 35772404

DOI: 10.1016/j.molcel.2022.06.008

Sequence Information:

  • Length: 1214
  • Mass: 136044
  • Checksum: 7B4ADA1E3F26813C
  • Sequence:
  • MERFRLEKKL PGPDEEAVVD LGKTSSTVNT KFEKEELESH RAVYIGVHVP FSKESRRRHR 
    HRGHKHHHRR RKDKESDKED GRESPSYDTP SQRVQFILGT EDDDEEHIPH DLFTEMDELC 
    YRDGEEYEWK ETARWLKFEE DVEDGGDRWS KPYVATLSLH SLFELRSCIL NGTVMLDMRA 
    STLDEIADMV LDNMIASGQL DESIRENVRE ALLKRHHHQN EKRFTSRIPL VRSFADIGKK 
    HSDPHLLERN GEGLSASRHS LRTGLSASNL SLRGESPLSL LLGHLLPSSR AGTPAGSRCT 
    TPVPTPQNSP PSSPSISRLT SRSSQESQRQ APELLVSPAS DDIPTVVIHP PEEDLEAALK 
    GEEQKNEENV DLTPGILASP QSAPGNLDNS KSGEIKGNGS GGSRENSTVD FSKVDMNFMR 
    KIPTGAEASN VLVGEVDFLE RPIIAFVRLA PAVLLTGLTE VPVPTRFLFL LLGPAGKAPQ 
    YHEIGRSIAT LMTDEIFHDV AYKAKDRNDL LSGIDEFLDQ VTVLPPGEWD PSIRIEPPKS 
    VPSQEKRKIP VFHNGSTPTL GETPKEAAHH AGPELQRTGR LFGGLILDIK RKAPFFLSDF 
    KDALSLQCLA SILFLYCACM SPVITFGGLL GEATEGRISA IESLFGASLT GIAYSLFAGQ 
    PLTILGSTGP VLVFEKILYK FCRDYQLSYL SLRTSIGLWT SFLCIVLVAT DASSLVCYIT 
    RFTEEAFAAL ICIIFIYEAL EKLFDLGETY AFNMHNNLDK LTSYSCVCTE PPNPSNETLA 
    QWKKDNITAH NISWRNLTVS ECKKLRGVFL GSACGHHGPY IPDVLFWCVI LFFTTFFLSS 
    FLKQFKTKRY FPTKVRSTIS DFAVFLTIVI MVTIDYLVGV PSPKLHVPEK FEPTHPERGW 
    IISPLGDNPW WTLLIAAIPA LLCTILIFMD QQITAVIINR KEHKLKKGAG YHLDLLMVGV 
    MLGVCSVMGL PWFVAATVLS ISHVNSLKVE SECSAPGEQP KFLGIREQRV TGLMIFILMG 
    LSVFMTSVLK FIPMPVLYGV FLYMGVSSLK GIQLFDRIKL FGMPAKHQPD LIYLRYVPLW 
    KVHIFTVIQL TCLVLLWVIK VSAAAVVFPM MVLALVFVRK LMDLCFTKRE LSWLDDLMPE 
    SKKKKEDDKK KKEKEEAERM LQDDDDTVHL PFEGGSLLQI PVKALKYSPD KPVSVKISFE 
    DEPRKKYVDA ETSL

Genular Protein ID: 551005486

Symbol: E9PFN4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15144186

Title: Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.

PubMed ID: 15144186

DOI: 10.1021/ac035352d

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 1210
  • Mass: 135303
  • Checksum: D14993C77B8076FC
  • Sequence:
  • MEADGAGEQM RPLLTRVTSR GPDEEAVVDL GKTSSTVNTK FEKEELESHR AVYIGVHVPF 
    SKESRRRHRH RGHKHHHRRR KDKESDKEDG RESPSYDTPS QRVQFILGTE DDDEEHIPHD 
    LFTEMDELCY RDGEEYEWKE TARWLKFEED VEDGGDRWSK PYVATLSLHS LFELRSCILN 
    GTVMLDMRAS TLDEIADMVL DNMIASGQLD ESIRENVREA LLKRHHHQNE KRFTSRIPLV 
    RSFADIGEGL SASRHSLRTG LSASNLSLRG ESPLSLLLGH LLPSSRAGTP AGSRCTTPVP 
    TPQNSPPSSP SISRLTSRSS QESQRQAPEL LVSPASDDIP TVVIHPPEED LEAALKGEEQ 
    KNEENVDLTP GILASPQSAP GNLDNSKSGE IKGNGSGGSR ENSTVDFSKV DMNFMRKIPT 
    GAEASNVLVG EVDFLERPII AFVRLAPAVL LTGLTEVPVP TRFLFLLLGP AGKAPQYHEI 
    GRSIATLMTD EIFHDVAYKA KDRNDLLSGI DEFLDQVTVL PPGEWDPSIR IEPPKSVPSQ 
    EKRKIPVFHN GSTPTLGETP KEAAHHAGPE LQRTGRLFGG LILDIKRKAP FFLSDFKDAL 
    SLQCLASILF LYCACMSPVI TFGGLLGEAT EGRISAIESL FGASLTGIAY SLFAGQPLTI 
    LGSTGPVLVF EKILYKFCRD YQLSYLSLRT SIGLWTSFLC IVLVATDASS LVCYITRFTE 
    EAFAALICII FIYEALEKLF DLGETYAFNM HNNLDKLTSY SCVCTEPPNP SNETLAQWKK 
    DNITAHNISW RNLTVSECKK LRGVFLGSAC GHHGPYIPDV LFWCVILFFT TFFLSSFLKQ 
    FKTKRYFPTK VRSTISDFAV FLTIVIMVTI DYLVGVPSPK LHVPEKFEPT HPERGWIISP 
    LGDNPWWTLL IAAIPALLCT ILIFMDQQIT AVIINRKEHK LKKGAGYHLD LLMVGVMLGV 
    CSVMGLPWFV AATVLSISHV NSLKVESECS APGEQPKFLG IREQRVTGLM IFILMGLSVF 
    MTSVLKFIPM PVLYGVFLYM GVSSLKGIQL FDRIKLFGMP AKHQPDLIYL RYVPLWKVHI 
    FTVIQLTCLV LLWVIKVSAA AVVFPMMVLA LVFVRKLMDL CFTKRELSWL DDLMPESKKK 
    KEDDKKKKEK EEAERMLQDD DDTVHLPFEG GSLLQIPVKA LKYSPDKPVS VKISFEDEPR 
    KKYVDAETSL

Genular Protein ID: 2598779927

Symbol: B5M450_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 1210
  • Mass: 135302
  • Checksum: 45237CD9F119A5A7
  • Sequence:
  • MEADGAGEQM RPLLTRVTSR GPDEEAVVDL GKTSSTVNTK FEKEELESHR AVYIGVHVPF 
    SKESRRRHRH RGHKHHHRRR KDKESDKEDG RESPSYDTPS QRVQFILGTE DDDEEHIPHD 
    LFTEMDELCY RDGEEYEWKE TARWLKFEED VEDGGDRWSK PYVATLSLHS LFELRSCILN 
    GTVMLDMRAS TLDEIADMVL DNMIASGQLD ESIRENVREA LLKRHHHQNE KRFTSRIPLV 
    RSFADIGEGL SASRHSLRTG LSASNLSLRG ESPLSLLLGH LLPSSRAGTP AGSRCTTPVP 
    TPQNSPPSSP SISRLTSRSS QKSQRQAPEL LVSPASDDIP TVVIHPPEED LEAALKGEEQ 
    KNEENVDLTP GILASPQSAP GNLDNSKSGE IKGNGSGGSR ENSTVDFSKV DMNFMRKIPT 
    GAEASNVLVG EVDFLERPII AFVRLAPAVL LTGLTEVPVP TRFLFLLLGP AGKAPQYHEI 
    GRSIATLMTD EIFHDVAYKA KDRNDLLSGI DEFLDQVTVL PPGEWDPSIR IEPPKSVPSQ 
    EKRKIPVFHN GSTPTLGETP KEAAHHAGPE LQRTGRLFGG LILDIKRKAP FFLSDFKDAL 
    SLQCLASILF LYCACMSPVI TFGGLLGEAT EGRISAIESL FGASLTGIAY SLFAGQPLTI 
    LGSTGPVLVF EKILYKFCRD YQLSYLSLRT SIGLWTSFLC IVLVATDASS LVCYITRFTE 
    EAFAALICII FIYEALEKLF DLGETYAFNM HNNLDKLTSY SCVCTEPPNP SNETLAQWKK 
    DNITAHNISW RNLTVSECKK LRGVFLGSAC GHHGPYIPDV LFWCVILFFT TFFLSSFLKQ 
    FKTKRYFPTK VRSTISDFAV FLTIVIMVTI DYLVGVPSPK LHVPEKFEPT HPERGWIISP 
    LGDNPWWTLL IAAIPALLCT ILIFMDQQIT AVIINRKEHK LKKGAGYHLD LLMVGVMLGV 
    CSVMGLPWFV AATVLSISHV NSLKVESECS APGEQPKFLG IREQRVTGLM IFILMGLSVF 
    MTSVLKFIPM PVLYGVFLYM GVSSLKGIQL FDRIKLFGMP AKHQPDLIYL RYVPLWKVHI 
    FTVIQLTCLV LLWVIKVSAA AVVFPMMVLA LVFVRKLMDL CFTKRELSWL DDLMPESKKK 
    KEDDKKKKEK EEAERMLQDD DDTVHLPFEG GSLLQIPVKA LKYSPDKPVS VKISFEDEPR 
    KKYVDAETSL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.