Details for: ACY1

Gene ID: 95

Symbol: ACY1

Ensembl ID: ENSG00000243989

Description: aminoacylase 1

Associated with

Other Information

Genular Protein ID: 3071519865

Symbol: ACY1_HUMAN

Name: Aminoacylase-1

UniProtKB Accession Codes:

Q03154 C9J6I6 C9J9D8 C9JWD4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 1 CTD 1 ChEBI 19 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 3 DrugCentral 1 EC 1 EMBL 7 EPD 1 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 6 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MEROPS 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PIR 1 PIRSF 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 REPRODUCTION-2DPAGE 1 RNAct 1 Reactome 3 RefSeq 5 Rhea 6 SABIO-RK 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8357837

Title: The nucleotide sequence of human aminoacylase-1.

PubMed ID: 8357837

DOI: 10.1016/0167-4781(93)90116-u

PubMed ID: 8394326

Title: Human aminoacylase-1. Cloning, sequence, and expression analysis of a chromosome 3p21 gene inactivated in small cell lung cancer.

PubMed ID: 8394326

DOI: 10.1016/s0021-9258(19)85294-8

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12933810

Title: Essential roles of zinc ligation and enzyme dimerization for catalysis in the aminoacylase-1/M20 family.

PubMed ID: 12933810

DOI: 10.1074/jbc.m304233200

PubMed ID: 16274666

Title: Aminoacylase I deficiency: a novel inborn error of metabolism.

PubMed ID: 16274666

DOI: 10.1016/j.bbrc.2005.10.126

PubMed ID: 16465618

Title: Mutations in ACY1, the gene encoding aminoacylase 1, cause a novel inborn error of metabolism.

PubMed ID: 16465618

DOI: 10.1086/500563

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 17562838

Title: Neurological findings in aminoacylase 1 deficiency.

PubMed ID: 17562838

DOI: 10.1212/01.wnl.0000264933.56204.e8

PubMed ID: 21414403

Title: The molecular basis of aminoacylase 1 deficiency.

PubMed ID: 21414403

DOI: 10.1016/j.bbadis.2011.03.005

Sequence Information:

  • Length: 408
  • Mass: 45885
  • Checksum: 293350CD7759826C
  • Sequence:
    • MTSKGPEEEH PSVTLFRQYL RIRTVQPKPD YGAAVAFFEE TARQLGLGCQ KVEVAPGYVV 
TVLTWPGTNP TLSSILLNSH TDVVPVFKEH WSHDPFEAFK DSEGYIYARG AQDMKCVSIQ 
YLEAVRRLKV EGHRFPRTIH MTFVPDEEVG GHQGMELFVQ RPEFHALRAG FALDEGIANP 
TDAFTVFYSE RSPWWVRVTS TGRPGHASRF MEDTAAEKLH KVVNSILAFR EKEWQRLQSN 
PHLKEGSVTS VNLTKLEGGV AYNVIPATMS ASFDFRVAPD VDFKAFEEQL QSWCQAAGEG 
VTLEFAQKWM HPQVTPTDDS NPWWAAFSRV CKDMNLTLEP EIMPAATDNR YIRAVGVPAL 
GFSPMNRTPV LLHDHDERLH EAVFLRGVDI YTRLLPALAS VPALPSDS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.