Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 63.5667
Cell Significance Index: -9.8900 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 29.5626
Cell Significance Index: -12.0100 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 23.8286
Cell Significance Index: -11.2500 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 19.2790
Cell Significance Index: -4.8900 - Cell Name: centroblast (CL0009112)
Fold Change: 14.5753
Cell Significance Index: 34.0100 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 8.1836
Cell Significance Index: -10.0900 - Cell Name: hepatic pit cell (CL2000054)
Fold Change: 3.9606
Cell Significance Index: 10.6100 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 3.2812
Cell Significance Index: -8.7900 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 3.2207
Cell Significance Index: 49.8300 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 2.6406
Cell Significance Index: -10.4200 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: 2.3385
Cell Significance Index: 32.7000 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 2.1886
Cell Significance Index: 141.2000 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 2.0739
Cell Significance Index: 244.5800 - Cell Name: early promyelocyte (CL0002154)
Fold Change: 1.0828
Cell Significance Index: 6.9100 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.7413
Cell Significance Index: 19.8300 - Cell Name: pro-T cell (CL0000827)
Fold Change: 0.5341
Cell Significance Index: 13.6500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.4924
Cell Significance Index: 93.7000 - Cell Name: late promyelocyte (CL0002151)
Fold Change: 0.3904
Cell Significance Index: 2.5900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.2846
Cell Significance Index: 28.1500 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.2550
Cell Significance Index: 5.2900 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.2428
Cell Significance Index: 6.2400 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.2375
Cell Significance Index: 214.4600 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 0.1701
Cell Significance Index: 1.7600 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1524
Cell Significance Index: 4.3900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.1510
Cell Significance Index: 24.5600 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.1212
Cell Significance Index: 2.1000 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.1175
Cell Significance Index: 12.7800 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.0948
Cell Significance Index: 2.0200 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.0676
Cell Significance Index: 4.0600 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.0458
Cell Significance Index: 1.3500 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0382
Cell Significance Index: 2.6400 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0381
Cell Significance Index: 1.3400 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.0334
Cell Significance Index: 0.4800 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0079
Cell Significance Index: 1.0100 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0062
Cell Significance Index: 3.4100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0053
Cell Significance Index: 4.0000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0029
Cell Significance Index: -5.3700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0049
Cell Significance Index: -7.5900 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0054
Cell Significance Index: -10.0400 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.0060
Cell Significance Index: -0.1500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0062
Cell Significance Index: -8.3800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0113
Cell Significance Index: -7.1600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0143
Cell Significance Index: -2.8300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0151
Cell Significance Index: -11.1600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0154
Cell Significance Index: -5.5100 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0174
Cell Significance Index: -12.7300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0176
Cell Significance Index: -3.5300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0182
Cell Significance Index: -11.3400 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0197
Cell Significance Index: -11.1200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0226
Cell Significance Index: -0.4900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0231
Cell Significance Index: -10.5000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0269
Cell Significance Index: -3.9100 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0330
Cell Significance Index: -9.4900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0331
Cell Significance Index: -1.5000 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0418
Cell Significance Index: -7.5300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0533
Cell Significance Index: -11.2300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0596
Cell Significance Index: -10.1800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0604
Cell Significance Index: -8.2900 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0648
Cell Significance Index: -3.9700 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0719
Cell Significance Index: -7.3400 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.0796
Cell Significance Index: -1.2000 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0814
Cell Significance Index: -10.0100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0855
Cell Significance Index: -9.9600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0863
Cell Significance Index: -9.8900 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0899
Cell Significance Index: -2.8800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0960
Cell Significance Index: -7.3700 - Cell Name: type II muscle cell (CL0002212)
Fold Change: -0.0967
Cell Significance Index: -1.5600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0982
Cell Significance Index: -10.2200 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0984
Cell Significance Index: -12.7100 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.1185
Cell Significance Index: -2.1900 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.1316
Cell Significance Index: -3.2100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1462
Cell Significance Index: -9.8300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1673
Cell Significance Index: -10.2800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1711
Cell Significance Index: -12.7500 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.1736
Cell Significance Index: -10.9400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1975
Cell Significance Index: -11.0800 - Cell Name: astrocyte (CL0000127)
Fold Change: -0.1997
Cell Significance Index: -2.2900 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.2048
Cell Significance Index: -10.6400 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2070
Cell Significance Index: -10.7800 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.2070
Cell Significance Index: -4.0400 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.2083
Cell Significance Index: -5.6700 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.2142
Cell Significance Index: -10.8200 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.2177
Cell Significance Index: -10.2300 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.2222
Cell Significance Index: -9.8300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.2276
Cell Significance Index: -10.6100 - Cell Name: fast muscle cell (CL0000190)
Fold Change: -0.2405
Cell Significance Index: -3.1500 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.2583
Cell Significance Index: -9.0500 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.2653
Cell Significance Index: -10.0500 - Cell Name: slow muscle cell (CL0000189)
Fold Change: -0.2707
Cell Significance Index: -4.0500 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.2749
Cell Significance Index: -10.0900 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.2812
Cell Significance Index: -4.7300 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.3070
Cell Significance Index: -10.0500 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.3096
Cell Significance Index: -9.8600 - Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
Fold Change: -0.3190
Cell Significance Index: -2.8400 - Cell Name: megakaryocyte progenitor cell (CL0000553)
Fold Change: -0.3200
Cell Significance Index: -2.3000 - Cell Name: pre-B-I cell (CL0000956)
Fold Change: -0.3257
Cell Significance Index: -1.5300 - Cell Name: mural cell (CL0008034)
Fold Change: -0.3327
Cell Significance Index: -4.0500 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: -0.3338
Cell Significance Index: -4.2300 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: -0.3347
Cell Significance Index: -4.1400 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.3367
Cell Significance Index: -8.9900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2579884226
Symbol: CD38_HUMAN
Name: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2319135
Title: Isolation of a cDNA encoding the human CD38 (T10) molecule, a cell surface glycoprotein with an unusual discontinuous pattern of expression during lymphocyte differentiation.
PubMed ID: 2319135
PubMed ID: 9074508
Title: Human gene encoding CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase): organization, nucleotide sequence and alternative splicing.
PubMed ID: 9074508
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1471258
Title: Similarities in amino acid sequences of Aplysia ADP-ribosyl cyclase and human lymphocyte antigen CD38.
PubMed ID: 1471258
PubMed ID: 8253715
Title: Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38 and inhibition of the hydrolysis by ATP.
PubMed ID: 8253715
PubMed ID: 7961800
Title: Essential cysteine residues for cyclic ADP-ribose synthesis and hydrolysis by CD38.
PubMed ID: 7961800
PubMed ID: 14759258
PubMed ID: 16690024
Title: NAADP+ synthesis from cADPRP and nicotinic acid by ADP-ribosyl cyclases.
PubMed ID: 16690024
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 19349973
Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.
PubMed ID: 19349973
DOI: 10.1038/nbt.1532
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 16154090
Title: Crystal structure of human CD38 extracellular domain.
PubMed ID: 16154090
PubMed ID: 9754820
Title: A missense mutation in the CD38 gene, a novel factor for insulin secretion: association with Type II diabetes mellitus in Japanese subjects and evidence of abnormal function when expressed in vitro.
PubMed ID: 9754820
Sequence Information:
- Length: 300
- Mass: 34328
- Checksum: 47BBE38C3DE3E6AA
- Sequence:
MANCEFSPVS GDKPCCRLSR RAQLCLGVSI LVLILVVVLA VVVPRWRQQW SGPGTTKRFP ETVLARCVKY TEIHPEMRHV DCQSVWDAFK GAFISKHPCN ITEEDYQPLM KLGTQTVPCN KILLWSRIKD LAHQFTQVQR DMFTLEDTLL GYLADDLTWC GEFNTSKINY QSCPDWRKDC SNNPVSVFWK TVSRRFAEAA CDVVHVMLNG SRSKIFDKNS TFGSVEVHNL QPEKVQTLEA WVIHGGREDS RDLCQDPTIK ELESIISKRN IQFSCKNIYR PDKFLQCVKN PEDSSCTSEI
Genular Protein ID: 896845194
Symbol: B4E006_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 160
- Mass: 17929
- Checksum: E95F0F14F0DCAA1F
- Sequence:
MANCEFSPVS GDKPCCRLSR IAQLCLGVSI LVLILVVVLA VVVPRWRQQW SGPGTTKRFP ETVLARCVKY TEIHPEMRHV DCQSVWDAFK GAFISKHPCN ITEEDYQPLM KLGTQTVPCN KKSTINLAQT GERTAATTLF QYSGKRFPAG LQKLPVMWSM
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.