CD38 | ENSG00000004468 | NCBI 952

Details for: CD38

Gene ID: 952

Symbol: CD38

Ensembl ID: ENSG00000004468

Description: CD38 molecule

Associated with

Metabolism
(R-HSA-1430728)
Metabolism of vitamins and cofactors
(R-HSA-196854)
Metabolism of water-soluble vitamins and cofactors
(R-HSA-196849)
Nicotinate metabolism
(R-HSA-196807)
Apoptotic signaling pathway
(GO:0097190)
Artery smooth muscle contraction
(GO:0014824)
Basolateral plasma membrane
(GO:0016323)
B cell proliferation
(GO:0042100)
B cell receptor signaling pathway
(GO:0050853)
Cell surface
(GO:0009986)
Extracellular exosome
(GO:0070062)
Female pregnancy
(GO:0007565)
Identical protein binding
(GO:0042802)
Long-term synaptic depression
(GO:0060292)
Membrane
(GO:0016020)
Nad+ nucleosidase activity
(GO:0003953)
Nad+ nucleotidase, cyclic adp-ribose generating
(GO:0061809)
Nad metabolic process
(GO:0019674)
Nadp+ nucleosidase activity
(GO:0050135)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of bone resorption
(GO:0045779)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of neuron projection development
(GO:0010977)
Phosphorus-oxygen lyase activity
(GO:0016849)
Plasma membrane
(GO:0005886)
Positive regulation of b cell proliferation
(GO:0030890)
Positive regulation of cell growth
(GO:0030307)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of insulin secretion
(GO:0032024)
Positive regulation of vasoconstriction
(GO:0045907)
Response to estradiol
(GO:0032355)
Response to hydroperoxide
(GO:0033194)
Response to hypoxia
(GO:0001666)
Response to interleukin-1
(GO:0070555)
Response to progesterone
(GO:0032570)
Response to retinoic acid
(GO:0032526)
Response to xenobiotic stimulus
(GO:0009410)
Signal transduction
(GO:0007165)
Transferase activity
(GO:0016740)

Other Information

Proteins

ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
B4E006_HUMAN

Genular Protein ID: 2579884226

Symbol: CD38_HUMAN

Name: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

UniProtKB Accession Codes:

P28907 O00121 O00122 Q96HY4

Database IDs:

Citations:

PubMed ID: 2319135

Title: Isolation of a cDNA encoding the human CD38 (T10) molecule, a cell surface glycoprotein with an unusual discontinuous pattern of expression during lymphocyte differentiation.

PubMed ID: 2319135

DOI: 10.4049/jimmunol.144.7.2811

PubMed ID: 9074508

Title: Human gene encoding CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase): organization, nucleotide sequence and alternative splicing.

PubMed ID: 9074508

DOI: 10.1016/s0378-1119(96)00723-8

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1471258

Title: Similarities in amino acid sequences of Aplysia ADP-ribosyl cyclase and human lymphocyte antigen CD38.

PubMed ID: 1471258

DOI: 10.1016/0968-0004(92)90337-9

PubMed ID: 8253715

Title: Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38 and inhibition of the hydrolysis by ATP.

PubMed ID: 8253715

DOI: 10.1016/s0021-9258(19)74275-6

PubMed ID: 7961800

Title: Essential cysteine residues for cyclic ADP-ribose synthesis and hydrolysis by CD38.

PubMed ID: 7961800

DOI: 10.1016/s0021-9258(19)61940-x

PubMed ID: 14759258

Title: An unappreciated role for RNA surveillance.

PubMed ID: 14759258

DOI: 10.1186/gb-2004-5-2-r8

PubMed ID: 16690024

Title: NAADP+ synthesis from cADPRP and nicotinic acid by ADP-ribosyl cyclases.

PubMed ID: 16690024

DOI: 10.1016/j.bbrc.2006.04.096

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 16154090

Title: Crystal structure of human CD38 extracellular domain.

PubMed ID: 16154090

DOI: 10.1016/j.str.2005.05.012

PubMed ID: 9754820

Title: A missense mutation in the CD38 gene, a novel factor for insulin secretion: association with Type II diabetes mellitus in Japanese subjects and evidence of abnormal function when expressed in vitro.

PubMed ID: 9754820

DOI: 10.1007/s001250051026

Sequence Information:

Length: 300
Mass: 34328
Checksum: 47BBE38C3DE3E6AA
Sequence:

MANCEFSPVS GDKPCCRLSR RAQLCLGVSI LVLILVVVLA VVVPRWRQQW SGPGTTKRFP 
ETVLARCVKY TEIHPEMRHV DCQSVWDAFK GAFISKHPCN ITEEDYQPLM KLGTQTVPCN 
KILLWSRIKD LAHQFTQVQR DMFTLEDTLL GYLADDLTWC GEFNTSKINY QSCPDWRKDC 
SNNPVSVFWK TVSRRFAEAA CDVVHVMLNG SRSKIFDKNS TFGSVEVHNL QPEKVQTLEA 
WVIHGGREDS RDLCQDPTIK ELESIISKRN IQFSCKNIYR PDKFLQCVKN PEDSSCTSEI

Genular Protein ID: 896845194

Symbol: B4E006_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4E006

Database IDs:

Sequence Information:

Length: 160
Mass: 17929
Checksum: E95F0F14F0DCAA1F
Sequence:

MANCEFSPVS GDKPCCRLSR IAQLCLGVSI LVLILVVVLA VVVPRWRQQW SGPGTTKRFP 
ETVLARCVKY TEIHPEMRHV DCQSVWDAFK GAFISKHPCN ITEEDYQPLM KLGTQTVPCN 
KKSTINLAQT GERTAATTLF QYSGKRFPAG LQKLPVMWSM

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CD38

Associated with

Other Information

Isolation of a cDNA encoding the human CD38 (T10) molecule, a cell surface glycoprotein with an unusual discontinuous pattern of expression during lymphocyte differentiation. PubMed ID: 2319135

Human gene encoding CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase): organization, nucleotide sequence and alternative splicing. PubMed ID: 9074508

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Similarities in amino acid sequences of Aplysia ADP-ribosyl cyclase and human lymphocyte antigen CD38. PubMed ID: 1471258

Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38 and inhibition of the hydrolysis by ATP. PubMed ID: 8253715

Essential cysteine residues for cyclic ADP-ribose synthesis and hydrolysis by CD38. PubMed ID: 7961800

An unappreciated role for RNA surveillance. PubMed ID: 14759258

NAADP+ synthesis from cADPRP and nicotinic acid by ADP-ribosyl cyclases. PubMed ID: 16690024

Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. PubMed ID: 19159218

Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins. PubMed ID: 19349973

Initial characterization of the human central proteome. PubMed ID: 21269460

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Crystal structure of human CD38 extracellular domain. PubMed ID: 16154090

A missense mutation in the CD38 gene, a novel factor for insulin secretion: association with Type II diabetes mellitus in Japanese subjects and evidence of abnormal function when expressed in vitro. PubMed ID: 9754820