ENTPD1 | ENSG00000138185 | NCBI 953

Details for: ENTPD1

Gene ID: 953

Symbol: ENTPD1

Ensembl ID: ENSG00000138185

Description: ectonucleoside triphosphate diphosphohydrolase 1

Associated with

Cell recruitment (pro-inflammatory response)
(R-HSA-9664424)
Disease
(R-HSA-1643685)
Infectious disease
(R-HSA-5663205)
Leishmania infection
(R-HSA-9658195)
Metabolism
(R-HSA-1430728)
Metabolism of nucleotides
(R-HSA-15869)
Nucleotide catabolism
(R-HSA-8956319)
Parasitic infection pathways
(R-HSA-9824443)
Phosphate bond hydrolysis by ntpdase proteins
(R-HSA-8850843)
Purinergic signaling in leishmaniasis infection
(R-HSA-9660826)
Adp phosphatase activity
(GO:0043262)
Apyrase activity
(GO:0004050)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Blood coagulation
(GO:0007596)
Caveola
(GO:0005901)
Cdp phosphatase activity
(GO:0036384)
Cell adhesion
(GO:0007155)
Ctpase activity
(GO:0043273)
Extracellular exosome
(GO:0070062)
Gdp phosphatase activity
(GO:0004382)
Gtpase activity
(GO:0003924)
Idp phosphatase activity
(GO:1990003)
Itpase activity
(GO:0103023)
Membrane
(GO:0016020)
Nucleoside diphosphate catabolic process
(GO:0009134)
Nucleoside diphosphate phosphatase activity
(GO:0017110)
Plasma membrane
(GO:0005886)
Platelet aggregation
(GO:0070527)
Protein binding
(GO:0005515)
Ribonucleoside triphosphate phosphatase activity
(GO:0017111)
Udp phosphatase activity
(GO:0045134)

Other Information

Proteins

ENTP1_HUMAN

Genular Protein ID: 469578330

Symbol: ENTP1_HUMAN

Name: N/A

UniProtKB Accession Codes:

P49961 A9Z1X8 B4DWB9 B4E1X1 B7Z599 G3XAF6 Q5T561 Q5T562 Q86VV3 Q9UQQ9 Q9Y3Q9

Database IDs:

Citations:

PubMed ID: 7930580

Title: The CD39 lymphoid cell activation antigen. Molecular cloning and structural characterization.

PubMed ID: 7930580

PubMed ID: 8955160

Title: Identification and characterization of CD39/vascular ATP diphosphohydrolase.

PubMed ID: 8955160

DOI: 10.1074/jbc.271.51.33116

PubMed ID: 10405171

Title: The cDNA cloning of human placental ecto-ATP diphosphohydrolases I and II.

PubMed ID: 10405171

DOI: 10.1016/s0014-5793(99)00751-6

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8529670

Title: Purification and properties of human placental ATP diphosphohydrolase.

PubMed ID: 8529670

DOI: 10.1111/j.1432-1033.1995.066_c.x

PubMed ID: 9846014

Title: Placental ecto-ATP diphosphohydrolase: its structural feature distinct from CD39, localization and inhibition on shear-induced platelet aggregation.

PubMed ID: 9846014

DOI: 10.1016/s0925-5710(98)00080-2

PubMed ID: 8996251

Title: Loss of ATP diphosphohydrolase activity with endothelial cell activation.

PubMed ID: 8996251

DOI: 10.1084/jem.185.1.153

PubMed ID: 8626624

Title: CD39 is an ecto-(Ca2+,Mg2+)-apyrase.

PubMed ID: 8626624

PubMed ID: 10636909

Title: Palmitoylation targets CD39/endothelial ATP diphosphohydrolase to caveolae.

PubMed ID: 10636909

DOI: 10.1074/jbc.275.3.2057

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 24482476

Title: Exome sequencing links corticospinal motor neuron disease to common neurodegenerative disorders.

PubMed ID: 24482476

DOI: 10.1126/science.1247363

Sequence Information:

Length: 510
Mass: 57965
Checksum: BAD87D2499649159
Sequence:

MEDTKESNVK TFCSKNILAI LGFSSIIAVI ALLAVGLTQN KALPENVKYG IVLDAGSSHT 
SLYIYKWPAE KENDTGVVHQ VEECRVKGPG ISKFVQKVNE IGIYLTDCME RAREVIPRSQ 
HQETPVYLGA TAGMRLLRME SEELADRVLD VVERSLSNYP FDFQGARIIT GQEEGAYGWI 
TINYLLGKFS QKTRWFSIVP YETNNQETFG ALDLGGASTQ VTFVPQNQTI ESPDNALQFR 
LYGKDYNVYT HSFLCYGKDQ ALWQKLAKDI QVASNEILRD PCFHPGYKKV VNVSDLYKTP 
CTKRFEMTLP FQQFEIQGIG NYQQCHQSIL ELFNTSYCPY SQCAFNGIFL PPLQGDFGAF 
SAFYFVMKFL NLTSEKVSQE KVTEMMKKFC AQPWEEIKTS YAGVKEKYLS EYCFSGTYIL 
SLLLQGYHFT ADSWEHIHFI GKIQGSDAGW TLGYMLNLTN MIPAEQPLST PLSHSTYVFL 
MVLFSLVLFT VAIIGLLIFH KPSYFWKDMV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ENTPD1

Associated with

Other Information

The CD39 lymphoid cell activation antigen. Molecular cloning and structural characterization. PubMed ID: 7930580

Identification and characterization of CD39/vascular ATP diphosphohydrolase. PubMed ID: 8955160

The cDNA cloning of human placental ecto-ATP diphosphohydrolases I and II. PubMed ID: 10405171

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and comparative analysis of human chromosome 10. PubMed ID: 15164054

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Purification and properties of human placental ATP diphosphohydrolase. PubMed ID: 8529670

Placental ecto-ATP diphosphohydrolase: its structural feature distinct from CD39, localization and inhibition on shear-induced platelet aggregation. PubMed ID: 9846014

Loss of ATP diphosphohydrolase activity with endothelial cell activation. PubMed ID: 8996251

CD39 is an ecto-(Ca2+,Mg2+)-apyrase. PubMed ID: 8626624

Palmitoylation targets CD39/endothelial ATP diphosphohydrolase to caveolae. PubMed ID: 10636909

Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. PubMed ID: 19159218

Exome sequencing links corticospinal motor neuron disease to common neurodegenerative disorders. PubMed ID: 24482476