APBA3 | ENSG00000011132 | NCBI 9546

Details for: APBA3

Gene ID: 9546

Symbol: APBA3

Ensembl ID: ENSG00000011132

Description: amyloid beta precursor protein binding family A member 3

Associated with

Neurexins and neuroligins
(R-HSA-6794361)
Neuronal system
(R-HSA-112316)
Protein-protein interactions at synapses
(R-HSA-6794362)
Amyloid-beta binding
(GO:0001540)
Chemical synaptic transmission
(GO:0007268)
Cytoplasm
(GO:0005737)
Dendritic spine
(GO:0043197)
Enzyme binding
(GO:0019899)
Enzyme inhibitor activity
(GO:0004857)
In utero embryonic development
(GO:0001701)
Negative regulation of catalytic activity
(GO:0043086)
Perinuclear region of cytoplasm
(GO:0048471)
Plasma membrane
(GO:0005886)
Protein binding
(GO:0005515)
Protein transport
(GO:0015031)
Regulation of gene expression
(GO:0010468)

Other Information

Proteins

Amyloid-beta A4 precursor protein-binding family A member 3

Genular Protein ID: 1274365661

Symbol: APBA3_HUMAN

Name: Amyloid-beta A4 precursor protein-binding family A member 3

UniProtKB Accession Codes:

O96018 O60483 Q9UPZ2

Database IDs:

Citations:

PubMed ID: 10049767

Title: X11L2, a new member of X11 protein family interacts with Alzheimer's beta-amyloid precursor protein.

PubMed ID: 10049767

DOI: 10.1006/bbrc.1999.0265

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10574372

Title: Genomic organization of the human X11L2 gene (APBA3), a third member of the X11 protein family interacting with Alzheimer's beta-amyloid precursor protein.

PubMed ID: 10574372

DOI: 10.1097/00001756-199908200-00025

PubMed ID: 9860131

Title: Mint 3: a ubiquitous mint isoform that does not bind to munc18-1 or -2.

PubMed ID: 9860131

DOI: 10.1016/s0171-9335(98)80103-9

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19726677

Title: Mint3 enhances the activity of hypoxia-inducible factor-1 (HIF-1) in macrophages by suppressing the activity of factor inhibiting HIF-1.

PubMed ID: 19726677

DOI: 10.1074/jbc.m109.019216

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26948053

Title: NECAB3 promotes activation of hypoxia-inducible factor-1 during normoxia and enhances tumourigenicity of cancer cells.

PubMed ID: 26948053

DOI: 10.1038/srep22784

Sequence Information:

Length: 575
Mass: 61454
Checksum: 3B910CC74C5F3840
Sequence:

MDFPTISRSP SGPPAMDLEG PRDILVPSED LTPDSQWDPM PGGPGSLSRM ELDESSLQEL 
VQQFEALPGD LVGPSPGGAP CPLHIATGHG LASQEIADAH GLLSAEAGRD DLLGLLHCEE 
CPPSQTGPEE PLEPAPRLLQ PPEDPDEDSD SPEWVEGASA EQEGSRSSSS SPEPWLETVP 
LVTPEEPPAG AQSPETLASY PAPQEVPGPC DHEDLLDGVI FGARYLGSTQ LVSERNPPTS 
TRMAQAREAM DRVKAPDGET QPMTEVDLFV STKRIKVLTA DSQEAMMDHA LHTISYTADI 
GCVLVLMARR RLARRPAPQD HGRRLYKMLC HVFYAEDAQL IAQAIGQAFA AAYSQFLRES 
GIDPSQVGVH PSPGACHLHN GDLDHFSNSD NCREVHLEKR RGEGLGVALV ESGWGSLLPT 
AVIANLLHGG PAERSGALSI GDRLTAINGT SLVGLPLAAC QAAVRETKSQ TSVTLSIVHC 
PPVTTAIIHR PHAREQLGFC VEDGIICSLL RGGIAERGGI RVGHRIIEIN GQSVVATPHA 
RIIELLTEAY GEVHIKTMPA ATYRLLTGQE QPVYL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: APBA3

Associated with

Other Information

X11L2, a new member of X11 protein family interacts with Alzheimer's beta-amyloid precursor protein. PubMed ID: 10049767

The DNA sequence and biology of human chromosome 19. PubMed ID: 15057824

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Genomic organization of the human X11L2 gene (APBA3), a third member of the X11 protein family interacting with Alzheimer's beta-amyloid precursor protein. PubMed ID: 10574372

Mint 3: a ubiquitous mint isoform that does not bind to munc18-1 or -2. PubMed ID: 9860131

Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. PubMed ID: 18691976

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Mint3 enhances the activity of hypoxia-inducible factor-1 (HIF-1) in macrophages by suppressing the activity of factor inhibiting HIF-1. PubMed ID: 19726677

Large-scale proteomics analysis of the human kinome. PubMed ID: 19369195

N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. PubMed ID: 22814378

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

NECAB3 promotes activation of hypoxia-inducible factor-1 during normoxia and enhances tumourigenicity of cancer cells. PubMed ID: 26948053