Details for: CHD1L

Gene ID: 9557

Symbol: CHD1L

Ensembl ID: ENSG00000131778

Description: chromodomain helicase DNA binding protein 1 like

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.84
    Marker Score: 892
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 1.34
    Marker Score: 1,076
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 1.34
    Marker Score: 1,680
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 1.3
    Marker Score: 17,294
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 1.29
    Marker Score: 1,858
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 1.25
    Marker Score: 1,116
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.14
    Marker Score: 17,782
  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: 1.12
    Marker Score: 680
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1.08
    Marker Score: 4,658
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.07
    Marker Score: 448
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 1.06
    Marker Score: 1,069
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 1.06
    Marker Score: 305
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,740
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47,964
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,399
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.97
    Marker Score: 6,252
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.95
    Marker Score: 715
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,402
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.94
    Marker Score: 5,066
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.94
    Marker Score: 485
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.93
    Marker Score: 440
  • Cell Name: oocyte (CL0000023)
    Fold Change: 0.92
    Marker Score: 227
  • Cell Name: erythroid progenitor cell, mammalian (CL0001066)
    Fold Change: 0.92
    Marker Score: 294
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,714
  • Cell Name: hematopoietic precursor cell (CL0008001)
    Fold Change: 0.9
    Marker Score: 316
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.89
    Marker Score: 5,102
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 0.88
    Marker Score: 2,099
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 0.88
    Marker Score: 804
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,294
  • Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
    Fold Change: 0.87
    Marker Score: 631
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.86
    Marker Score: 311
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 0.86
    Marker Score: 1,793
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 0.84
    Marker Score: 535
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.84
    Marker Score: 1,368
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 0.82
    Marker Score: 332
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.82
    Marker Score: 406
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.82
    Marker Score: 924
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 0.81
    Marker Score: 307
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.81
    Marker Score: 1,646
  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 0.8
    Marker Score: 2,187
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.8
    Marker Score: 4,787
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.79
    Marker Score: 3,226
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.78
    Marker Score: 313
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 0.78
    Marker Score: 213
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 0.77
    Marker Score: 279
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.76
    Marker Score: 952
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 0.76
    Marker Score: 380
  • Cell Name: promyelocyte (CL0000836)
    Fold Change: 0.76
    Marker Score: 377
  • Cell Name: early lymphoid progenitor (CL0000936)
    Fold Change: 0.76
    Marker Score: 372
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.75
    Marker Score: 1,282
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.75
    Marker Score: 450
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.75
    Marker Score: 572
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 0.74
    Marker Score: 389
  • Cell Name: Unknown (CL0002371)
    Fold Change: 0.73
    Marker Score: 779
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.73
    Marker Score: 489
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.73
    Marker Score: 378
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 0.73
    Marker Score: 1,272
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 0.72
    Marker Score: 268
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 0.71
    Marker Score: 226
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.71
    Marker Score: 645
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 0.7
    Marker Score: 17,995
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.7
    Marker Score: 7,111
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.69
    Marker Score: 2,898
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.68
    Marker Score: 1,604
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 0.68
    Marker Score: 452
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 0.67
    Marker Score: 953
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.67
    Marker Score: 172
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.67
    Marker Score: 1,901
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 0.66
    Marker Score: 231
  • Cell Name: interneuron (CL0000099)
    Fold Change: 0.66
    Marker Score: 300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.65
    Marker Score: 2,559
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 0.65
    Marker Score: 1,530
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 0.65
    Marker Score: 1,244
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.64
    Marker Score: 307
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 0.64
    Marker Score: 234
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 0.64
    Marker Score: 362
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: 0.63
    Marker Score: 3,828
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 0.63
    Marker Score: 351
  • Cell Name: Unknown (CL0000548)
    Fold Change: 0.62
    Marker Score: 454
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 0.62
    Marker Score: 432
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 0.61
    Marker Score: 574
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.61
    Marker Score: 195
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 0.61
    Marker Score: 154
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 0.6
    Marker Score: 803
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 0.6
    Marker Score: 643
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.59
    Marker Score: 1,750
  • Cell Name: thymocyte (CL0000893)
    Fold Change: 0.59
    Marker Score: 617
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.59
    Marker Score: 519
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 0.58
    Marker Score: 146
  • Cell Name: stem cell (CL0000034)
    Fold Change: 0.58
    Marker Score: 1,375
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.58
    Marker Score: 239
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 0.58
    Marker Score: 317
  • Cell Name: neural cell (CL0002319)
    Fold Change: 0.57
    Marker Score: 277
  • Cell Name: nephron tubule epithelial cell (CL1000494)
    Fold Change: 0.57
    Marker Score: 134
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.57
    Marker Score: 282
  • Cell Name: common dendritic progenitor (CL0001029)
    Fold Change: 0.57
    Marker Score: 197
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.57
    Marker Score: 313
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: 0.57
    Marker Score: 316
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.57
    Marker Score: 588
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.56
    Marker Score: 609

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** CHD1L is a member of the CHD family of proteins, which are known for their roles in chromatin remodeling, DNA repair, and transcriptional regulation. This gene exhibits high sequence similarity to CHD1, a well-studied gene involved in the regulation of gene expression and DNA repair. CHD1L's chromodomain and helicase domains enable it to interact with histones, DNA, and other chromatin-associated proteins, facilitating its functions in chromatin remodeling and DNA repair. **Pathways and Functions:** CHD1L's multifaceted nature is reflected in its involvement in various cellular pathways, including: 1. **Chromatin Remodeling:** CHD1L's helicase and chromodomain domains enable it to unwind and reorganize chromatin structure, influencing gene expression and transcriptional regulation. 2. **DNA Repair:** CHD1L participates in the repair of DNA double-strand breaks, double-strand breaks, and nucleotide excision repair, ensuring genome stability and preventing genetic instability. 3. **Histone Reader Activity:** CHD1L's chromodomain domain allows it to interact with histone modifications, enabling the regulation of gene expression and chromatin structure. 4. **Nucleosome Binding:** CHD1L's ability to bind nucleosomes enables it to regulate chromatin structure and gene expression. 5. **DNA Duplex Unwinding:** CHD1L's helicase activity facilitates the unwinding of DNA duplexes, necessary for DNA repair and replication. **Clinical Significance:** The clinical significance of CHD1L is multifaceted and far-reaching. Alterations in CHD1L expression have been linked to various diseases, including: 1. **Cancer:** CHD1L's involvement in chromatin remodeling and DNA repair suggests its potential role in cancer development and progression. 2. **Neurological Disorders:** CHD1L's involvement in histone reader activity and chromatin remodeling may contribute to the pathogenesis of neurological disorders, such as Alzheimer's disease and Parkinson's disease. 3. **Cardiovascular Diseases:** CHD1L's expression in cardiac muscle cells and epicardial adipocytes suggests its potential role in cardiovascular disease development and progression. In conclusion, CHD1L is a complex gene involved in chromatin remodeling, DNA repair, and transcriptional regulation. Its clinical significance is multifaceted, and further research is necessary to fully elucidate its role in various diseases. As an expert immunologist, I emphasize the importance of continued investigation into CHD1L's functions and potential therapeutic applications.

Genular Protein ID: 3410251625

Symbol: CHD1L_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q86WJ1 A5YM64 B4DDE1 B5MDZ7 Q53EZ3 Q5VXX7 Q6DD94 Q6PK83 Q86XH3 Q96HF7 Q96SP3 Q9BVJ1 Q9NVV8

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 3 ChEBI 6 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 13 EMDB 5 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 17 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 2 HPA 1 InParanoid 1 IntAct 1 InterPro 9 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 13 PDBsum 6 PRO 1 PROSITE 4 PROSITE-ProRule 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 Reactome 2 RefSeq 16 Rhea 2 SAM 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 18023026

Title: Isolation and characterization of a novel oncogene, amplified in liver cancer 1, within a commonly amplified region at 1q21 in hepatocellular carcinoma.

PubMed ID: 18023026

DOI: 10.1002/hep.22072

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19661379

Title: Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1.

PubMed ID: 19661379

DOI: 10.1126/science.1177321

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23891004

Title: Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins.

PubMed ID: 23891004

DOI: 10.1016/j.cmet.2013.06.015

PubMed ID: 29320706

Title: Human CIA2A-FAM96A and CIA2B-FAM96B Integrate Iron Homeostasis and Maturation of Different Subsets of Cytosolic-Nuclear Iron-Sulfur Proteins.

PubMed ID: 29320706

DOI: 10.1016/j.cmet.2017.12.009

PubMed ID: 29220652

Title: Mechanistic insights into autoinhibition of the oncogenic chromatin remodeler ALC1.

PubMed ID: 29220652

DOI: 10.1016/j.molcel.2017.10.017

PubMed ID: 29220653

Title: A Poly-ADP-Ribose trigger releases the auto-inhibition of a chromatin remodeling oncogene.

PubMed ID: 29220653

DOI: 10.1016/j.molcel.2017.11.019

PubMed ID: 33275888

Title: The oncogenic helicase ALC1 regulates PARP inhibitor potency by trapping PARP2 at DNA breaks.

PubMed ID: 33275888

DOI: 10.1016/j.molcel.2020.10.009

PubMed ID: 34874266

Title: Serine ADP-ribosylation marks nucleosomes for ALC1-dependent chromatin remodeling.

PubMed ID: 34874266

DOI: 10.7554/elife.71502

PubMed ID: 34465625

Title: Multiple roles for PARP1 in ALC1-dependent nucleosome remodeling.

PubMed ID: 34465625

DOI: 10.1073/pnas.2107277118

PubMed ID: 33357431

Title: Mechanistic insights into regulation of the ALC1 remodeler by the nucleosome acidic patch.

PubMed ID: 33357431

DOI: 10.1016/j.celrep.2020.108529

PubMed ID: 34210977

Title: Structural basis of ALC1/CHD1L autoinhibition and the mechanism of activation by the nucleosome.

PubMed ID: 34210977

DOI: 10.1038/s41467-021-24320-4

PubMed ID: 34486521

Title: Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome.

PubMed ID: 34486521

DOI: 10.7554/elife.71420

Sequence Information:

  • Length: 897
  • Mass: 101000
  • Checksum: 226A1F8A44A8F9FE
  • Sequence:
    • MERAGATSRG GQAPGFLLRL HTEGRAEAAR VQEQDLRQWG LTGIHLRSYQ LEGVNWLAQR 
FHCQNGCILG DEMGLGKTCQ TIALFIYLAG RLNDEGPFLI LCPLSVLSNW KEEMQRFAPG 
LSCVTYAGDK EERACLQQDL KQESRFHVLL TTYEICLKDA SFLKSFPWSV LVVDEAHRLK 
NQSSLLHKTL SEFSVVFSLL LTGTPIQNSL QELYSLLSFV EPDLFSKEEV GDFIQRYQDI 
EKESESASEL HKLLQPFLLR RVKAEVATEL PKKTEVVIYH GMSALQKKYY KAILMKDLDA 
FENETAKKVK LQNILSQLRK CVDHPYLFDG VEPEPFEVGD HLTEASGKLH LLDKLLAFLY 
SGGHRVLLFS QMTQMLDILQ DYMDYRGYSY ERVDGSVRGE ERHLAIKNFG QQPIFVFLLS 
TRAGGVGMNL TAADTVIFVD SDFNPQNDLQ AAARAHRIGQ NKSVKVIRLI GRDTVEEIVY 
RKAASKLQLT NMIIEGGHFT LGAQKPAADA DLQLSEILKF GLDKLLASEG STMDEIDLES 
ILGETKDGQW VSDALPAAEG GSRDQEEGKN HMYLFEGKDY SKEPSKEDRK SFEQLVNLQK 
TLLEKASQEG RSLRNKGSVL IPGLVEGSTK RKRVLSPEEL EDRQKKRQEA AAKRRRLIEE 
KKRQKEEAEH KKKMAWWESN NYQSFCLPSE ESEPEDLENG EESSAELDYQ DPDATSLKYV 
SGDVTHPQAG AEDALIVHCV DDSGHWGRGG LFTALEKRSA EPRKIYELAG KMKDLSLGGV 
LLFPVDDKES RNKGQDLLAL IVAQHRDRSN VLSGIKMAAL EEGLKKIFLA AKKKKASVHL 
PRIGHATKGF NWYGTERLIR KHLAARGIPT YIYYFPRSKS AVLHSQSSSS SSRQLVP

Genular Protein ID: 1917431780

Symbol: A0A0A0MRH8_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MRH8

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 ChiTaRS 1 DNASU 1 EMBL 1 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 7 Gene3D 3 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 IntAct 1 InterPro 7 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PeptideAtlas 1 Pfam 2 Proteomes 2 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 745
  • Mass: 83720
  • Checksum: 367D48B1C0896933
  • Sequence:
    • MERAGATSRG GQAPGFLLRL HTEGRAEAAR VQEQDLRQWG LTVVFSLLLT GTPIQNSLQE 
LYSLLSFVEP DLFSKEEVGD FIQRYQDIEK ESESASELHK LLQPFLLRRV KAEVATELPK 
KTEVVIYHGM SALQKKYYKA ILMKDLDAFE NETAKKVKLQ NILSQLRKCV DHPYLFDGVE 
PEPFEVGDHL TEASGKLHLL DKLLAFLYSG GHRVLLFSQM TQMLDILQDY MDYRGYSYER 
VDGSVRGEER HLAIKNFGQQ PIFVFLLSTR AGGVGMNLTA ADTVIFVDSD FNPQNDLQAA 
ARAHRIGQNK SVKVIRLIGR DTVEEIVYRK AASKLQLTNM IIEGGHFTLG AQKPAADADL 
QLSEILKFGL DKLLASEGST MDEIDLESIL GETKDGQWVS DALPAAEGGS RDQEEGKNHM 
YLFEGKDYSK EPSKEDRKSF EQLVNLQKTL LEKASQEGRS LRNKGSVLIP GLVEGSTKRK 
RVLSPEELED RQKKRQEAAA KRRRLIEEKK RQKEEAEHKK KMAWWESNNY QSFCLPSEES 
EPEDLENGEE SSAELDYQDP DATSLKYVSG DVTHPQAGAE DALIVHCVDD SGHWGRGGLF 
TALEKRSAEP RKIYELAGKM KDLSLGGVLL FPVDDKESRN KGQDLLALIV AQHRDRSNVL 
SGIKMAALEE GLKKIFLAAK KKKASVHLPR IGHATKGFNW YGTERLIRKH LAARGIPTYI 
YYFPRSKSAV LHSQSSSSSS RQLVP

Genular Protein ID: 2697159745

Symbol: A0A0A0MSH9_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MSH9

Database IDs:

ARBA 3 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 ChiTaRS 1 DNASU 1 EMBL 1 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 8 Gene3D 3 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 9 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 7 PeptideAtlas 1 Pfam 2 Proteomes 2 RefSeq 2 SAM 1 SMART 2 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 825
  • Mass: 92956
  • Checksum: 6165F75F29B73310
  • Sequence:
    • MGLGKTCQTI ALFIYLAGRL NDEGPFLILC PLSVLSNWKE EMQRFAPGLS CVTYAGDKEE 
RACLQQDLKQ ESRFHVLLTT YEICLKDASF LKSFPWSVLV VDEAHRLKNQ SSLLHKTLSE 
FSVVFSLLLT GTPIQNSLQE LYSLLSFVEP DLFSKEEVGD FIQRYQDIEK ESESASELHK 
LLQPFLLRRV KAEVATELPK KTEVVIYHGM SALQKKYYKA ILMKDLDAFE NETAKKVKLQ 
NILSQLRKCV DHPYLFDGVE PEPFEVGDHL TEASGKLHLL DKLLAFLYSG GHRVLLFSQM 
TQMLDILQDY MDYRGYSYER VDGSVRGEER HLAIKNFGQQ PIFVFLLSTR AGGVGMNLTA 
ADTVIFVDSD FNPQNDLQAA ARAHRIGQNK SVKVIRLIGR DTVEEIVYRK AASKLQLTNM 
IIEGGHFTLG AQKPAADADL QLSEILKFGL DKLLASEGST MDEIDLESIL GETKDGQWVS 
DALPAAEGGS RDQEEGKNHM YLFEGKDYSK EPSKEDRKSF EQLVNLQKTL LEKASQEGRS 
LRNKGSVLIP GLVEGSTKRK RVLSPEELED RQKKRQEAAA KRRRLIEEKK RQKEEAEHKK 
KMAWWESNNY QSFCLPSEES EPEDLENGEE SSAELDYQDP DATSLKYVSG DVTHPQAGAE 
DALIVHCVDD SGHWGRGGLF TALEKRSAEP RKIYELAGKM KDLSLGGVLL FPVDDKESRN 
KGQDLLALIV AQHRDRSNVL SGIKMAALEE GLKKIFLAAK KKKASVHLPR IGHATKGFNW 
YGTERLIRKH LAARGIPTYI YYFPRSKSAV LHSQSSSSSS RQLVP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.