Details for: CHD1L

Gene ID: 9557

Symbol: CHD1L

Ensembl ID: ENSG00000131778

Description: chromodomain helicase DNA binding protein 1 like

Associated with

Other Information

Genular Protein ID: 3410251625

Symbol: CHD1L_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q86WJ1 A5YM64 B4DDE1 B5MDZ7 Q53EZ3 Q5VXX7 Q6DD94 Q6PK83 Q86XH3 Q96HF7 Q96SP3 Q9BVJ1 Q9NVV8

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 3 ChEBI 6 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 13 EMDB 5 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 17 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 2 HPA 1 InParanoid 1 IntAct 1 InterPro 9 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 13 PDBsum 6 PRO 1 PROSITE 4 PROSITE-ProRule 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 Reactome 2 RefSeq 16 Rhea 2 SAM 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 18023026

Title: Isolation and characterization of a novel oncogene, amplified in liver cancer 1, within a commonly amplified region at 1q21 in hepatocellular carcinoma.

PubMed ID: 18023026

DOI: 10.1002/hep.22072

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19661379

Title: Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1.

PubMed ID: 19661379

DOI: 10.1126/science.1177321

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23891004

Title: Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins.

PubMed ID: 23891004

DOI: 10.1016/j.cmet.2013.06.015

PubMed ID: 29320706

Title: Human CIA2A-FAM96A and CIA2B-FAM96B Integrate Iron Homeostasis and Maturation of Different Subsets of Cytosolic-Nuclear Iron-Sulfur Proteins.

PubMed ID: 29320706

DOI: 10.1016/j.cmet.2017.12.009

PubMed ID: 29220652

Title: Mechanistic insights into autoinhibition of the oncogenic chromatin remodeler ALC1.

PubMed ID: 29220652

DOI: 10.1016/j.molcel.2017.10.017

PubMed ID: 29220653

Title: A Poly-ADP-Ribose trigger releases the auto-inhibition of a chromatin remodeling oncogene.

PubMed ID: 29220653

DOI: 10.1016/j.molcel.2017.11.019

PubMed ID: 33275888

Title: The oncogenic helicase ALC1 regulates PARP inhibitor potency by trapping PARP2 at DNA breaks.

PubMed ID: 33275888

DOI: 10.1016/j.molcel.2020.10.009

PubMed ID: 34874266

Title: Serine ADP-ribosylation marks nucleosomes for ALC1-dependent chromatin remodeling.

PubMed ID: 34874266

DOI: 10.7554/elife.71502

PubMed ID: 34465625

Title: Multiple roles for PARP1 in ALC1-dependent nucleosome remodeling.

PubMed ID: 34465625

DOI: 10.1073/pnas.2107277118

PubMed ID: 33357431

Title: Mechanistic insights into regulation of the ALC1 remodeler by the nucleosome acidic patch.

PubMed ID: 33357431

DOI: 10.1016/j.celrep.2020.108529

PubMed ID: 34210977

Title: Structural basis of ALC1/CHD1L autoinhibition and the mechanism of activation by the nucleosome.

PubMed ID: 34210977

DOI: 10.1038/s41467-021-24320-4

PubMed ID: 34486521

Title: Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome.

PubMed ID: 34486521

DOI: 10.7554/elife.71420

Sequence Information:

  • Length: 897
  • Mass: 101000
  • Checksum: 226A1F8A44A8F9FE
  • Sequence:
    • MERAGATSRG GQAPGFLLRL HTEGRAEAAR VQEQDLRQWG LTGIHLRSYQ LEGVNWLAQR 
FHCQNGCILG DEMGLGKTCQ TIALFIYLAG RLNDEGPFLI LCPLSVLSNW KEEMQRFAPG 
LSCVTYAGDK EERACLQQDL KQESRFHVLL TTYEICLKDA SFLKSFPWSV LVVDEAHRLK 
NQSSLLHKTL SEFSVVFSLL LTGTPIQNSL QELYSLLSFV EPDLFSKEEV GDFIQRYQDI 
EKESESASEL HKLLQPFLLR RVKAEVATEL PKKTEVVIYH GMSALQKKYY KAILMKDLDA 
FENETAKKVK LQNILSQLRK CVDHPYLFDG VEPEPFEVGD HLTEASGKLH LLDKLLAFLY 
SGGHRVLLFS QMTQMLDILQ DYMDYRGYSY ERVDGSVRGE ERHLAIKNFG QQPIFVFLLS 
TRAGGVGMNL TAADTVIFVD SDFNPQNDLQ AAARAHRIGQ NKSVKVIRLI GRDTVEEIVY 
RKAASKLQLT NMIIEGGHFT LGAQKPAADA DLQLSEILKF GLDKLLASEG STMDEIDLES 
ILGETKDGQW VSDALPAAEG GSRDQEEGKN HMYLFEGKDY SKEPSKEDRK SFEQLVNLQK 
TLLEKASQEG RSLRNKGSVL IPGLVEGSTK RKRVLSPEEL EDRQKKRQEA AAKRRRLIEE 
KKRQKEEAEH KKKMAWWESN NYQSFCLPSE ESEPEDLENG EESSAELDYQ DPDATSLKYV 
SGDVTHPQAG AEDALIVHCV DDSGHWGRGG LFTALEKRSA EPRKIYELAG KMKDLSLGGV 
LLFPVDDKES RNKGQDLLAL IVAQHRDRSN VLSGIKMAAL EEGLKKIFLA AKKKKASVHL 
PRIGHATKGF NWYGTERLIR KHLAARGIPT YIYYFPRSKS AVLHSQSSSS SSRQLVP

Genular Protein ID: 1917431780

Symbol: A0A0A0MRH8_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MRH8

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 ChiTaRS 1 DNASU 1 EMBL 1 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 7 Gene3D 3 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 IntAct 1 InterPro 7 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PeptideAtlas 1 Pfam 2 Proteomes 2 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 745
  • Mass: 83720
  • Checksum: 367D48B1C0896933
  • Sequence:
    • MERAGATSRG GQAPGFLLRL HTEGRAEAAR VQEQDLRQWG LTVVFSLLLT GTPIQNSLQE 
LYSLLSFVEP DLFSKEEVGD FIQRYQDIEK ESESASELHK LLQPFLLRRV KAEVATELPK 
KTEVVIYHGM SALQKKYYKA ILMKDLDAFE NETAKKVKLQ NILSQLRKCV DHPYLFDGVE 
PEPFEVGDHL TEASGKLHLL DKLLAFLYSG GHRVLLFSQM TQMLDILQDY MDYRGYSYER 
VDGSVRGEER HLAIKNFGQQ PIFVFLLSTR AGGVGMNLTA ADTVIFVDSD FNPQNDLQAA 
ARAHRIGQNK SVKVIRLIGR DTVEEIVYRK AASKLQLTNM IIEGGHFTLG AQKPAADADL 
QLSEILKFGL DKLLASEGST MDEIDLESIL GETKDGQWVS DALPAAEGGS RDQEEGKNHM 
YLFEGKDYSK EPSKEDRKSF EQLVNLQKTL LEKASQEGRS LRNKGSVLIP GLVEGSTKRK 
RVLSPEELED RQKKRQEAAA KRRRLIEEKK RQKEEAEHKK KMAWWESNNY QSFCLPSEES 
EPEDLENGEE SSAELDYQDP DATSLKYVSG DVTHPQAGAE DALIVHCVDD SGHWGRGGLF 
TALEKRSAEP RKIYELAGKM KDLSLGGVLL FPVDDKESRN KGQDLLALIV AQHRDRSNVL 
SGIKMAALEE GLKKIFLAAK KKKASVHLPR IGHATKGFNW YGTERLIRKH LAARGIPTYI 
YYFPRSKSAV LHSQSSSSSS RQLVP

Genular Protein ID: 2697159745

Symbol: A0A0A0MSH9_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MSH9

Database IDs:

ARBA 3 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 ChiTaRS 1 DNASU 1 EMBL 1 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 8 Gene3D 3 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 9 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 7 PeptideAtlas 1 Pfam 2 Proteomes 2 RefSeq 2 SAM 1 SMART 2 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 825
  • Mass: 92956
  • Checksum: 6165F75F29B73310
  • Sequence:
    • MGLGKTCQTI ALFIYLAGRL NDEGPFLILC PLSVLSNWKE EMQRFAPGLS CVTYAGDKEE 
RACLQQDLKQ ESRFHVLLTT YEICLKDASF LKSFPWSVLV VDEAHRLKNQ SSLLHKTLSE 
FSVVFSLLLT GTPIQNSLQE LYSLLSFVEP DLFSKEEVGD FIQRYQDIEK ESESASELHK 
LLQPFLLRRV KAEVATELPK KTEVVIYHGM SALQKKYYKA ILMKDLDAFE NETAKKVKLQ 
NILSQLRKCV DHPYLFDGVE PEPFEVGDHL TEASGKLHLL DKLLAFLYSG GHRVLLFSQM 
TQMLDILQDY MDYRGYSYER VDGSVRGEER HLAIKNFGQQ PIFVFLLSTR AGGVGMNLTA 
ADTVIFVDSD FNPQNDLQAA ARAHRIGQNK SVKVIRLIGR DTVEEIVYRK AASKLQLTNM 
IIEGGHFTLG AQKPAADADL QLSEILKFGL DKLLASEGST MDEIDLESIL GETKDGQWVS 
DALPAAEGGS RDQEEGKNHM YLFEGKDYSK EPSKEDRKSF EQLVNLQKTL LEKASQEGRS 
LRNKGSVLIP GLVEGSTKRK RVLSPEELED RQKKRQEAAA KRRRLIEEKK RQKEEAEHKK 
KMAWWESNNY QSFCLPSEES EPEDLENGEE SSAELDYQDP DATSLKYVSG DVTHPQAGAE 
DALIVHCVDD SGHWGRGGLF TALEKRSAEP RKIYELAGKM KDLSLGGVLL FPVDDKESRN 
KGQDLLALIV AQHRDRSNVL SGIKMAALEE GLKKIFLAAK KKKASVHLPR IGHATKGFNW 
YGTERLIRKH LAARGIPTYI YYFPRSKSAV LHSQSSSSSS RQLVP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.