Details for: VPS26A

Gene ID: 9559

Symbol: VPS26A

Ensembl ID: ENSG00000122958

Description: VPS26 retromer complex component A

Associated with

Other Information

Genular Protein ID: 988618794

Symbol: VP26A_HUMAN

Name: Vacuolar protein sorting-associated protein 26A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11102511

Title: Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes.

PubMed ID: 11102511

DOI: 10.1091/mbc.11.12.4105

PubMed ID: 9653160

Title: Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning.

PubMed ID: 9653160

DOI: 10.1073/pnas.95.14.8175

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15078902

Title: Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer.

PubMed ID: 15078902

DOI: 10.1083/jcb.200312034

PubMed ID: 15078903

Title: Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor.

PubMed ID: 15078903

DOI: 10.1083/jcb.200312055

PubMed ID: 15247922

Title: The mammalian retromer regulates transcytosis of the polymeric immunoglobulin receptor.

PubMed ID: 15247922

DOI: 10.1038/ncb1153

PubMed ID: 16315276

Title: Model-guided microarray implicates the retromer complex in Alzheimer's disease.

PubMed ID: 16315276

DOI: 10.1002/ana.20667

PubMed ID: 16190980

Title: A novel mammalian retromer component, Vps26B.

PubMed ID: 16190980

DOI: 10.1111/j.1600-0854.2005.00328.x

PubMed ID: 16407403

Title: An essential role for SNX1 in lysosomal sorting of protease-activated receptor-1: evidence for retromer-, Hrs-, and Tsg101-independent functions of sorting nexins.

PubMed ID: 16407403

DOI: 10.1091/mbc.e05-09-0899

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 16784798

Title: No association of vacuolar protein sorting 26 polymorphisms with Alzheimer's disease.

PubMed ID: 16784798

DOI: 10.1016/j.neurobiolaging.2006.05.009

PubMed ID: 17868075

Title: EHD1 interacts with retromer to stabilize SNX1 tubules and facilitate endosome-to-Golgi retrieval.

PubMed ID: 17868075

DOI: 10.1111/j.1600-0854.2007.00652.x

PubMed ID: 19619496

Title: The retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network.

PubMed ID: 19619496

DOI: 10.1016/j.devcel.2009.04.016

PubMed ID: 19531583

Title: Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5.

PubMed ID: 19531583

DOI: 10.1242/jcs.048686

PubMed ID: 20682791

Title: A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components.

PubMed ID: 20682791

DOI: 10.1074/jbc.m110.154120

PubMed ID: 20923837

Title: The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics.

PubMed ID: 20923837

DOI: 10.1242/jcs.071472

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21602791

Title: SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors.

PubMed ID: 21602791

DOI: 10.1038/ncb2252

PubMed ID: 21725319

Title: A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion.

PubMed ID: 21725319

DOI: 10.1038/ncb2281

PubMed ID: 22070227

Title: Recruitment of the endosomal WASH complex is mediated by the extended 'tail' of Fam21 binding to the retromer protein Vps35.

PubMed ID: 22070227

DOI: 10.1042/bj20111761

PubMed ID: 22279231

Title: Retromer binds the FANSHY sorting motif in SorLA to regulate amyloid precursor protein sorting and processing.

PubMed ID: 22279231

DOI: 10.1523/jneurosci.2272-11.2012

PubMed ID: 22431521

Title: The role of ceroid lipofuscinosis neuronal protein 5 (CLN5) in endosomal sorting.

PubMed ID: 22431521

DOI: 10.1128/mcb.06726-11

PubMed ID: 23563491

Title: A global analysis of SNX27-retromer assembly and cargo specificity reveals a function in glucose and metal ion transport.

PubMed ID: 23563491

DOI: 10.1038/ncb2721

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24344282

Title: A mechanism for retromer endosomal coat complex assembly with cargo.

PubMed ID: 24344282

DOI: 10.1073/pnas.1316482111

PubMed ID: 28892079

Title: Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling.

PubMed ID: 28892079

DOI: 10.1038/ncb3610

PubMed ID: 30213940

Title: SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion.

PubMed ID: 30213940

DOI: 10.1038/s41467-018-06114-3

PubMed ID: 16732284

Title: The retromer subunit Vps26 has an arrestin fold and binds Vps35 through its C-terminal domain.

PubMed ID: 16732284

DOI: 10.1038/nsmb1103

Sequence Information:

  • Length: 327
  • Mass: 38170
  • Checksum: BD3B2EAA6CFCBFA9
  • Sequence:
  • MSFLGGFFGP ICEIDIVLND GETRKMAEMK TEDGKVEKHY LFYDGESVSG KVNLAFKQPG 
    KRLEHQGIRI EFVGQIELFN DKSNTHEFVN LVKELALPGE LTQSRSYDFE FMQVEKPYES 
    YIGANVRLRY FLKVTIVRRL TDLVKEYDLI VHQLATYPDV NNSIKMEVGI EDCLHIEFEY 
    NKSKYHLKDV IVGKIYFLLV RIKIQHMELQ LIKKEITGIG PSTTTETETI AKYEIMDGAP 
    VKGESIPIRL FLAGYDPTPT MRDVNKKFSV RYFLNLVLVD EEDRRYFKQQ EIILWRKAPE 
    KLRKQRTNFH QRFESPESQA SAEQPEM

Genular Protein ID: 2127962591

Symbol: B4DLT1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 310
  • Mass: 36571
  • Checksum: 756A047C16E2AD9A
  • Sequence:
  • MTENPFQERY SVEDLSTFGM CLCMVRYVYD AFYKVNLAFK QPGKRLEHQG IRIEFVGQIE 
    LFNDKSNTHE FVNLVKELAL PGELTQSRSY DFEFMQVEKP YESYIGANVR LRYFLKVTIV 
    RRLTDLVKEY DLIVHQLATY PDVNNSIKME VGIEDCLHIE FEYNKSKYHL KDVIVGKIYF 
    LLVRIKIQHM ELQPIKKEIT GIGPSTTTET ETIAKYEIMD GAPVKGESIP IRLFLAGYDP 
    TPTMRDVNKK FSVRYFLNLV LVDEEDRRYF KQQEIILWRK APEKLRKQRT NFHQRFESPE 
    SQASAEQPEM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.