Details for: BCAR1
Associated with
Other Information
Genular Protein ID: 3806855293
Symbol: BCAR1_HUMAN
Name: Breast cancer anti-estrogen resistance protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10639512
Title: BCAR1, a human homologue of the adapter protein p130Cas, induces anti-estrogen resistance in breast cancer cells.
PubMed ID: 10639512
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15616553
Title: The sequence and analysis of duplication-rich human chromosome 16.
PubMed ID: 15616553
DOI: 10.1038/nature03187
PubMed ID: 9020138
Title: Involvement of p130(Cas) and p105(HEF1), a novel Cas-like docking protein, in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on human B cells.
PubMed ID: 9020138
PubMed ID: 10502414
Title: Dimerization of the docking/adaptor protein HEF1 via a carboxy-terminal helix-loop-helix domain.
PubMed ID: 10502414
PubMed ID: 10587647
Title: Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas.
PubMed ID: 10587647
DOI: 10.1038/70302
PubMed ID: 11158326
Title: SH2-containing inositol 5'-phosphatase SHIP2 associates with the p130(Cas) adapter protein and regulates cellular adhesion and spreading.
PubMed ID: 11158326
PubMed ID: 12432078
Title: Novel function of Chat in controlling cell adhesion via Cas-Crk-C3G-pathway-mediated Rap1 activation.
PubMed ID: 12432078
DOI: 10.1242/jcs.00207
PubMed ID: 12832404
Title: p130Cas Couples the tyrosine kinase Bmx/Etk with regulation of the actin cytoskeleton and cell migration.
PubMed ID: 12832404
PubMed ID: 17174122
Title: The hematopoietic isoform of Cas-Hef1-associated signal transducer regulates chemokine-induced inside-out signaling and T cell trafficking.
PubMed ID: 17174122
PubMed ID: 17038317
Title: Ack1 mediates Cdc42-dependent cell migration and signaling to p130Cas.
PubMed ID: 17038317
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19454314
Title: AND-34/BCAR3 regulates adhesion-dependent p130Cas serine phosphorylation and breast cancer cell growth pattern.
PubMed ID: 19454314
PubMed ID: 19086031
Title: Pyk2 mediates endothelin-1 signaling via p130Cas/BCAR3 cascade and regulates human glomerular mesangial cell adhesion and spreading.
PubMed ID: 19086031
DOI: 10.1002/jcp.21649
PubMed ID: 19147981
Title: Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling.
PubMed ID: 19147981
DOI: 10.1172/jci37160
PubMed ID: 20798394
Title: Comprehensive analysis of phosphorylation sites in Tensin1 reveals regulation by p38MAPK.
PubMed ID: 20798394
PubMed ID: 20534451
Title: Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression.
PubMed ID: 20534451
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22801373
Title: Protein tyrosine phosphatase alpha phosphotyrosyl-789 binds BCAR3 to position Cas for activation at integrin-mediated focal adhesions.
PubMed ID: 22801373
DOI: 10.1128/mcb.00214-12
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 22710723
Title: Identification and functional characterization of p130Cas as a substrate of protein tyrosine phosphatase nonreceptor 14.
PubMed ID: 22710723
DOI: 10.1038/onc.2012.220
PubMed ID: 15784259
Title: The 1.1 A resolution crystal structure of the p130cas SH3 domain and ramifications for ligand selectivity.
PubMed ID: 15784259
PubMed ID: 22081014
Title: NSP-Cas protein structures reveal a promiscuous interaction module in cell signaling.
PubMed ID: 22081014
DOI: 10.1038/nsmb.2152
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
Sequence Information:
- Length: 870
- Mass: 93372
- Checksum: B81EC3430049E795
- Sequence:
MNHLNVLAKA LYDNVAESPD ELSFRKGDIM TVLEQDTQGL DGWWLCSLHG RQGIVPGNRL KILVGMYDKK PAGPGPGPPA TPAQPQPGLH APAPPASQYT PMLPNTYQPQ PDSVYLVPTP SKAQQGLYQV PGPSPQFQSP PAKQTSTFSK QTPHHPFPSP ATDLYQVPPG PGGPAQDIYQ VPPSAGMGHD IYQVPPSMDT RSWEGTKPPA KVVVPTRVGQ GYVYEAAQPE QDEYDIPRHL LAPGPQDIYD VPPVRGLLPS QYGQEVYDTP PMAVKGPNGR DPLLEVYDVP PSVEKGLPPS NHHAVYDVPP SVSKDVPDGP LLREETYDVP PAFAKAKPFD PARTPLVLAA PPPDSPPAED VYDVPPPAPD LYDVPPGLRR PGPGTLYDVP RERVLPPEVA DGGVVDSGVY AVPPPAEREA PAEGKRLSAS STGSTRSSQS ASSLEVAGPG REPLELEVAV EALARLQQGV SATVAHLLDL AGSAGATGSW RSPSEPQEPL VQDLQAAVAA VQSAVHELLE FARSAVGNAA HTSDRALHAK LSRQLQKMED VHQTLVAHGQ ALDAGRGGSG ATLEDLDRLV ACSRAVPEDA KQLASFLHGN ASLLFRRTKA TAPGPEGGGT LHPNPTDKTS SIQSRPLPSP PKFTSQDSPD GQYENSEGGW MEDYDYVHLQ GKEEFEKTQK ELLEKGSITR QGKSQLELQQ LKQFERLEQE VSRPIDHDLA NWTPAQPLAP GRTGGLGPSD RQLLLFYLEQ CEANLTTLTN AVDAFFTAVA TNQPPKIFVA HSKFVILSAH KLVFIGDTLS RQAKAADVRS QVTHYSNLLC DLLRGIVATT KAAALQYPSP SAAQDMVERV KELGHSTQQF RRVLGQLAAA
Genular Protein ID: 1048918404
Symbol: B3KWE2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
Sequence Information:
- Length: 660
- Mass: 70853
- Checksum: F9F664008FA6F5A3
- Sequence:
MVVVPTRVGQ GYVYEAAQPE QDEYDIPRHL LAPGPQDIYD VPPVRGLLPS QYGQEVYDTP PMAVKGPNGR DPLLEVYDVP PSVEKGLPPS NHHAVYDVPP SVSKDVPDGP LLREETYDVP PAFAKAKPFD PARTPLVLAA PPPDSPPAED VYDVPPPAPD LYDVPPGLRR PGPGTLYDVP RERVLPPEVA DGGVVDSGVY AVPPPAEREA PAEGKRLSAS STGSTRSSQS ASSLEVAGPG REPLELEVAV EALARLQQGV SATVAHLLDL AGSAGATGSW RSPSEPQEPL VQDLQAAVAA VQSAVHELLE FARSAVGNAA HTSDRALHAK LSRQLQKMED VHQTLVAHGQ ALDAGRGGSG ATLEDLDRLV ACSRAVPEDA KQLASFLHGN ASLLFRRTKA TAPGPEGGGT LHPNPTDKTS SIQSRPLPSP PKFTSQDSPD GQYENSEGGW MEDYDYVHLQ GKEEFEKTQK ELLEKGSITR QGKSQLELQQ LKQFERLEQE VSRPIDHDLA NWTPAQPLAP GRTGGLGPSD RQLLLFYLEQ CEANLTTLTN AVDAFFTAVA TNQPPKIFVA HSKFVILSAH KLVFIGDTLS RQAKAADVRS QVTHYSNLLC DLLRGIVATT KAAALQYPSP SAAQDMVERV KELGHSTQQF RRVLGQLAAA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.