Details for: CD40

Gene ID: 958

Symbol: CD40

Ensembl ID: ENSG00000101017

Description: CD40 molecule

Associated with

Other Information

Genular Protein ID: 3302504540

Symbol: TNR5_HUMAN

Name: Tumor necrosis factor receptor superfamily member 5

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2475341

Title: A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas.

PubMed ID: 2475341

DOI: 10.1002/j.1460-2075.1989.tb03521.x

PubMed ID: 11172023

Title: Regulation of CD40 function by its isoforms generated through alternative splicing.

PubMed ID: 11172023

DOI: 10.1073/pnas.98.4.1751

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2463309

Title: Biochemical characteristics and partial amino acid sequence of the receptor-like human B cell and carcinoma antigen CDw40.

PubMed ID: 2463309

PubMed ID: 15340161

Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.

PubMed ID: 15340161

DOI: 10.1110/ps.04682504

PubMed ID: 11676606

Title: Determination of carbohydrate structures N-linked to soluble CD154 and characterization of the interactions of CD40 with CD154 expressed in Pichia pastoris and Chinese hamster ovary cells.

PubMed ID: 11676606

DOI: 10.1006/prep.2001.1501

PubMed ID: 7530216

Title: A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40.

PubMed ID: 7530216

DOI: 10.1016/0014-5793(94)01406-q

PubMed ID: 7533327

Title: Involvement of CRAF1, a relative of TRAF, in CD40 signaling.

PubMed ID: 7533327

DOI: 10.1126/science.7533327

PubMed ID: 9718306

Title: CD40-tumor necrosis factor receptor-associated factor (TRAF) interactions: regulation of CD40 signaling through multiple TRAF binding sites and TRAF hetero-oligomerization.

PubMed ID: 9718306

DOI: 10.1021/bi981067q

PubMed ID: 9511754

Title: Cloning and characterization of a cDNA encoding the human homolog of tumor necrosis factor receptor-associated factor 5 (TRAF5).

PubMed ID: 9511754

DOI: 10.1016/s0378-1119(97)00616-1

PubMed ID: 9432981

Title: Tumor necrosis factor receptor-associated factor 6 (TRAF6) stimulates extracellular signal-regulated kinase (ERK) activity in CD40 signaling along a ras-independent pathway.

PubMed ID: 9432981

DOI: 10.1084/jem.187.2.237

PubMed ID: 31331973

Title: Integrin Binding to the Trimeric Interface of CD40L Plays a Critical Role in CD40/CD40L Signaling.

PubMed ID: 31331973

DOI: 10.4049/jimmunol.1801630

PubMed ID: 9037712

Title: Construction and analysis of a detailed three-dimensional model of the ligand binding domain of the human B cell receptor CD40.

PubMed ID: 9037712

DOI: 10.1002/(sici)1097-0134(199701)27:1<59::aid-prot7>3.3.co;2-z

PubMed ID: 9605317

Title: The role of polar interactions in the molecular recognition of CD40L with its receptor CD40.

PubMed ID: 9605317

DOI: 10.1002/pro.5560070506

PubMed ID: 10984535

Title: Molecular basis for CD40 signaling mediated by TRAF3.

PubMed ID: 10984535

DOI: 10.1073/pnas.97.19.10395

PubMed ID: 12005438

Title: Downstream regulator TANK binds to the CD40 recognition site on TRAF3.

PubMed ID: 12005438

DOI: 10.1016/s0969-2126(02)00733-5

PubMed ID: 11675497

Title: Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM.

PubMed ID: 11675497

DOI: 10.1073/pnas.221456898

PubMed ID: 26545377

Title: Novel and recurrent AID mutations underlie prevalent autosomal recessive form of HIGM in consanguineous patients.

PubMed ID: 26545377

DOI: 10.1007/s00251-015-0878-6

Sequence Information:

  • Length: 277
  • Mass: 30619
  • Checksum: BC8776EC2C4A5680
  • Sequence:
  • MVRLPLQCVL WGCLLTAVHP EPPTACREKQ YLINSQCCSL CQPGQKLVSD CTEFTETECL 
    PCGESEFLDT WNRETHCHQH KYCDPNLGLR VQQKGTSETD TICTCEEGWH CTSEACESCV 
    LHRSCSPGFG VKQIATGVSD TICEPCPVGF FSNVSSAFEK CHPWTSCETK DLVVQQAGTN 
    KTDVVCGPQD RLRALVVIPI IFGILFAILL VLVFIKKVAK KPTNKAPHPK QEPQEINFPD 
    DLPGSNTAAP VQETLHGCQP VTQEDGKESR ISVQERQ

Genular Protein ID: 4077534413

Symbol: Q6P2H9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 151
  • Mass: 17079
  • Checksum: EBAA27CE7592172B
  • Sequence:
  • MVRLPLQCVL WGCLLTAVHP EPPTACREKQ YLINSQCCSL CQPGQKLVSD CTEFTETECL 
    PCGESEFLDT WNRETHFHQH KYCDPNLGLR VQQKGTSETD TICTCEEGWH CTSEACESCV 
    LHRSCSPGFG VKQIDICQPH FPKDRGLNLL M

Genular Protein ID: 1939260178

Symbol: A0A0S2Z349_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 26871637

Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

PubMed ID: 26871637

DOI: 10.1016/j.cell.2016.01.029

Sequence Information:

  • Length: 225
  • Mass: 25099
  • Checksum: C1D131836FDBC45D
  • Sequence:
  • MVRLPLQCVL WGCLLTAVHP EPPTACREKQ YLINSQCCSL CQPGQKLVSD CTEFTETECL 
    PCGESEFLDT WNRETHCHQH KYCDPNLGLR VQQKGTSETD TICTCEEGWH CTSEACESCV 
    LHRSCSPGFG VKQIGPQDRL RALVVIPIIF GILFAILLVL VFIKKVAKKP TNKAPHPKQE 
    PQEINFPDDL PGSNTAAPVQ ETLHGCQPVT QEDGKESRIS VQERQ

Genular Protein ID: 3970765748

Symbol: A0A8Q3SI60_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

Sequence Information:

  • Length: 237
  • Mass: 25769
  • Checksum: D663417BA2E0E4DE
  • Sequence:
  • MVRLPLQCVL WGCLLTAVHP EPPTACREKQ YLINSQCCSL CQPGQKLVSD CTEFTETECL 
    PCGESEFLDT WNRETHCHQH KYCDPNLGLR VQQKGTSETD TICTCEEGWH CTSEACESCV 
    LHRSCSPGFG VKQIATGVSD TICEPCPVGF FSNVSSAFEK CHPWTSCETK DLVVQQAGTN 
    KTDVVCGESW TMGPGESLGR SPGSAESPGG DPHHLRDPVC HPLGAGLYQK GGQEANQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.