Details for: CD40

Gene ID: 958

Symbol: CD40

Ensembl ID: ENSG00000101017

Description: CD40 molecule

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 125.4940
    Cell Significance Index: -19.5200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 76.7810
    Cell Significance Index: -19.4800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 44.1838
    Cell Significance Index: -17.9500
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 38.9397
    Cell Significance Index: -20.0300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 15.9698
    Cell Significance Index: -19.6900
  • Cell Name: centroblast (CL0009112)
    Fold Change: 14.8046
    Cell Significance Index: 34.5400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 7.4808
    Cell Significance Index: -20.0400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.0025
    Cell Significance Index: -19.7400
  • Cell Name: centrocyte (CL0009111)
    Fold Change: 3.3439
    Cell Significance Index: 10.3100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 2.8893
    Cell Significance Index: 340.7400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.3619
    Cell Significance Index: 64.2900
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 2.0538
    Cell Significance Index: 14.7500
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 1.8196
    Cell Significance Index: 32.1600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.7767
    Cell Significance Index: 50.9300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.6877
    Cell Significance Index: 87.9100
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 1.4691
    Cell Significance Index: 6.5700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.3133
    Cell Significance Index: 213.6000
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 1.1655
    Cell Significance Index: 9.7900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.1325
    Cell Significance Index: 1022.5800
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 1.0994
    Cell Significance Index: 12.4900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.7744
    Cell Significance Index: 99.2700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.7300
    Cell Significance Index: 9.9600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7285
    Cell Significance Index: 79.2400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.4892
    Cell Significance Index: 29.3700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4310
    Cell Significance Index: 53.0000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.3807
    Cell Significance Index: 17.7500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3723
    Cell Significance Index: 25.7500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.3573
    Cell Significance Index: 18.5600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2890
    Cell Significance Index: 52.1100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2077
    Cell Significance Index: 20.5500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1857
    Cell Significance Index: 101.4300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1580
    Cell Significance Index: 69.8500
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.1377
    Cell Significance Index: 2.1300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0831
    Cell Significance Index: 15.8200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0535
    Cell Significance Index: 2.7000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0358
    Cell Significance Index: 0.7800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0081
    Cell Significance Index: 15.2400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0038
    Cell Significance Index: 0.1400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0007
    Cell Significance Index: 0.0500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0026
    Cell Significance Index: -1.9400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0046
    Cell Significance Index: -0.4700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0087
    Cell Significance Index: -1.4800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0097
    Cell Significance Index: -17.9700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0119
    Cell Significance Index: -7.5600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0132
    Cell Significance Index: -20.3400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0147
    Cell Significance Index: -6.6800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0188
    Cell Significance Index: -25.5200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0215
    Cell Significance Index: -14.8500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0235
    Cell Significance Index: -17.2400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0243
    Cell Significance Index: -18.0200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0250
    Cell Significance Index: -0.7200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0342
    Cell Significance Index: -19.3100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0352
    Cell Significance Index: -4.8400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0356
    Cell Significance Index: -22.2100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0364
    Cell Significance Index: -1.6500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0420
    Cell Significance Index: -15.0500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0427
    Cell Significance Index: -6.2100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0431
    Cell Significance Index: -1.3800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0559
    Cell Significance Index: -16.0900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0562
    Cell Significance Index: -2.6400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0604
    Cell Significance Index: -6.9200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0671
    Cell Significance Index: -8.6700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0724
    Cell Significance Index: -14.5200
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.0782
    Cell Significance Index: -1.2400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0812
    Cell Significance Index: -1.7300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0854
    Cell Significance Index: -16.9500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1027
    Cell Significance Index: -21.6300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1260
    Cell Significance Index: -3.5200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1265
    Cell Significance Index: -6.6400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1275
    Cell Significance Index: -14.8600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1507
    Cell Significance Index: -9.7300
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.1661
    Cell Significance Index: -2.6700
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.1837
    Cell Significance Index: -1.1100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1878
    Cell Significance Index: -19.5500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1949
    Cell Significance Index: -14.5300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.2268
    Cell Significance Index: -5.6700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2351
    Cell Significance Index: -18.0400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2414
    Cell Significance Index: -19.1200
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: -0.2515
    Cell Significance Index: -2.0800
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: -0.2556
    Cell Significance Index: -1.1800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2701
    Cell Significance Index: -16.5600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2802
    Cell Significance Index: -18.8400
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.3017
    Cell Significance Index: -12.3600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3086
    Cell Significance Index: -19.4500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.3614
    Cell Significance Index: -6.6800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3644
    Cell Significance Index: -22.4000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.3802
    Cell Significance Index: -10.1700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3963
    Cell Significance Index: -22.2400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.4002
    Cell Significance Index: -17.7000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.4002
    Cell Significance Index: -7.8100
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.4161
    Cell Significance Index: -6.2700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.4307
    Cell Significance Index: -11.0700
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: -0.4330
    Cell Significance Index: -2.6800
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.4358
    Cell Significance Index: -18.9500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.4807
    Cell Significance Index: -14.1600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.4835
    Cell Significance Index: -10.1200
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.5078
    Cell Significance Index: -18.6400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.5115
    Cell Significance Index: -19.3700
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.5359
    Cell Significance Index: -4.3700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.5498
    Cell Significance Index: -19.2600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **B cell activation**: CD40 is a key receptor for B cell activation, which is essential for the development of humoral immunity. The binding of CD40 to CD154 on T cells triggers a cascade of signaling events that lead to the activation, proliferation, and differentiation of B cells. 2. **Immune cell coordination**: CD40 is expressed on various immune cells, including dendritic cells, macrophages, and B cells, and plays a crucial role in coordinating immune responses through its interaction with CD154 on T cells. 3. **Cytokine production**: CD40 signaling is essential for the production of cytokines, including IL-6, TNF-α, and IL-12, which are critical for the regulation of immune responses. 4. **Inflammation regulation**: CD40 signaling can regulate inflammation by inducing the production of anti-inflammatory cytokines, such as IL-10. **Pathways and Functions:** 1. **CD40 signaling pathway**: The CD40 signaling pathway involves the binding of CD40 to CD154 on T cells, which triggers a cascade of signaling events that lead to the activation, proliferation, and differentiation of B cells. 2. **Phosphatidylinositol 3-kinase/protein kinase B (PI3K/PKB) signal transduction**: CD40 signaling activates the PI3K/PKB pathway, which is essential for the activation of B cells and the regulation of immune responses. 3. **NF-κB signaling pathway**: CD40 signaling activates the NF-κB pathway, which is essential for the regulation of immune responses, including the production of cytokines and the activation of immune cells. **Clinical Significance:** 1. **Autoimmune diseases**: CD40 has been implicated in the pathogenesis of autoimmune diseases, including rheumatoid arthritis, lupus, and multiple sclerosis. 2. **Cancer**: CD40 has been shown to be overexpressed in various types of cancer, including breast, lung, and colon cancer, and has been implicated in the development of cancer. 3. **Immunotherapy**: CD40 has been targeted in immunotherapies, including checkpoint inhibitors and cancer vaccines, to enhance immune responses against cancer and autoimmune diseases. 4. **Infectious diseases**: CD40 has been implicated in the pathogenesis of infectious diseases, including HIV, tuberculosis, and malaria. In conclusion, CD40 is a critical regulator of the immune system, and its dysregulation has been implicated in various diseases, including autoimmune diseases, cancer, and infectious diseases. Understanding the mechanisms of CD40 signaling and its clinical significance is essential for the development of novel therapeutic strategies to modulate immune responses and treat these diseases.

Genular Protein ID: 3302504540

Symbol: TNR5_HUMAN

Name: Tumor necrosis factor receptor superfamily member 5

UniProtKB Accession Codes:

P25942 E1P5S9 Q53GN5 Q5JY15 Q5U007 Q7M4Q8 Q86YK5 Q9BYU0

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CPTAC 2 CPTC 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 ELM 1 EMBL 12 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 46 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 12 PDBsum 12 PIR 2 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 3 RefSeq 4 SASBDB 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2475341

Title: A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas.

PubMed ID: 2475341

DOI: 10.1002/j.1460-2075.1989.tb03521.x

PubMed ID: 11172023

Title: Regulation of CD40 function by its isoforms generated through alternative splicing.

PubMed ID: 11172023

DOI: 10.1073/pnas.98.4.1751

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2463309

Title: Biochemical characteristics and partial amino acid sequence of the receptor-like human B cell and carcinoma antigen CDw40.

PubMed ID: 2463309

PubMed ID: 15340161

Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.

PubMed ID: 15340161

DOI: 10.1110/ps.04682504

PubMed ID: 11676606

Title: Determination of carbohydrate structures N-linked to soluble CD154 and characterization of the interactions of CD40 with CD154 expressed in Pichia pastoris and Chinese hamster ovary cells.

PubMed ID: 11676606

DOI: 10.1006/prep.2001.1501

PubMed ID: 7530216

Title: A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40.

PubMed ID: 7530216

DOI: 10.1016/0014-5793(94)01406-q

PubMed ID: 7533327

Title: Involvement of CRAF1, a relative of TRAF, in CD40 signaling.

PubMed ID: 7533327

DOI: 10.1126/science.7533327

PubMed ID: 9718306

Title: CD40-tumor necrosis factor receptor-associated factor (TRAF) interactions: regulation of CD40 signaling through multiple TRAF binding sites and TRAF hetero-oligomerization.

PubMed ID: 9718306

DOI: 10.1021/bi981067q

PubMed ID: 9511754

Title: Cloning and characterization of a cDNA encoding the human homolog of tumor necrosis factor receptor-associated factor 5 (TRAF5).

PubMed ID: 9511754

DOI: 10.1016/s0378-1119(97)00616-1

PubMed ID: 9432981

Title: Tumor necrosis factor receptor-associated factor 6 (TRAF6) stimulates extracellular signal-regulated kinase (ERK) activity in CD40 signaling along a ras-independent pathway.

PubMed ID: 9432981

DOI: 10.1084/jem.187.2.237

PubMed ID: 31331973

Title: Integrin Binding to the Trimeric Interface of CD40L Plays a Critical Role in CD40/CD40L Signaling.

PubMed ID: 31331973

DOI: 10.4049/jimmunol.1801630

PubMed ID: 9037712

Title: Construction and analysis of a detailed three-dimensional model of the ligand binding domain of the human B cell receptor CD40.

PubMed ID: 9037712

DOI: 10.1002/(sici)1097-0134(199701)27:1<59::aid-prot7>3.3.co;2-z

PubMed ID: 9605317

Title: The role of polar interactions in the molecular recognition of CD40L with its receptor CD40.

PubMed ID: 9605317

DOI: 10.1002/pro.5560070506

PubMed ID: 10984535

Title: Molecular basis for CD40 signaling mediated by TRAF3.

PubMed ID: 10984535

DOI: 10.1073/pnas.97.19.10395

PubMed ID: 12005438

Title: Downstream regulator TANK binds to the CD40 recognition site on TRAF3.

PubMed ID: 12005438

DOI: 10.1016/s0969-2126(02)00733-5

PubMed ID: 11675497

Title: Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM.

PubMed ID: 11675497

DOI: 10.1073/pnas.221456898

PubMed ID: 26545377

Title: Novel and recurrent AID mutations underlie prevalent autosomal recessive form of HIGM in consanguineous patients.

PubMed ID: 26545377

DOI: 10.1007/s00251-015-0878-6

Sequence Information:

  • Length: 277
  • Mass: 30619
  • Checksum: BC8776EC2C4A5680
  • Sequence:
    • MVRLPLQCVL WGCLLTAVHP EPPTACREKQ YLINSQCCSL CQPGQKLVSD CTEFTETECL 
PCGESEFLDT WNRETHCHQH KYCDPNLGLR VQQKGTSETD TICTCEEGWH CTSEACESCV 
LHRSCSPGFG VKQIATGVSD TICEPCPVGF FSNVSSAFEK CHPWTSCETK DLVVQQAGTN 
KTDVVCGPQD RLRALVVIPI IFGILFAILL VLVFIKKVAK KPTNKAPHPK QEPQEINFPD 
DLPGSNTAAP VQETLHGCQP VTQEDGKESR ISVQERQ

Genular Protein ID: 1939260178

Symbol: A0A0S2Z349_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0S2Z349

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 22 Gene3D 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 3 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 26871637

Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

PubMed ID: 26871637

DOI: 10.1016/j.cell.2016.01.029

Sequence Information:

  • Length: 225
  • Mass: 25099
  • Checksum: C1D131836FDBC45D
  • Sequence:
    • MVRLPLQCVL WGCLLTAVHP EPPTACREKQ YLINSQCCSL CQPGQKLVSD CTEFTETECL 
PCGESEFLDT WNRETHCHQH KYCDPNLGLR VQQKGTSETD TICTCEEGWH CTSEACESCV 
LHRSCSPGFG VKQIGPQDRL RALVVIPIIF GILFAILLVL VFIKKVAKKP TNKAPHPKQE 
PQEINFPDDL PGSNTAAPVQ ETLHGCQPVT QEDGKESRIS VQERQ

Genular Protein ID: 4077534413

Symbol: Q6P2H9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6P2H9

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 22 Gene3D 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 1 RefSeq 3 SAM 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 151
  • Mass: 17079
  • Checksum: EBAA27CE7592172B
  • Sequence:
    • MVRLPLQCVL WGCLLTAVHP EPPTACREKQ YLINSQCCSL CQPGQKLVSD CTEFTETECL 
PCGESEFLDT WNRETHFHQH KYCDPNLGLR VQQKGTSETD TICTCEEGWH CTSEACESCV 
LHRSCSPGFG VKQIDICQPH FPKDRGLNLL M

Genular Protein ID: 3970765748

Symbol: A0A8Q3SI60_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A8Q3SI60

Database IDs:

ARBA 12 CDD 1 CTD 1 DisGeNET 1 EMBL 1 Ensembl 2 GO 4 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 NCBI Taxonomy 1 PANTHER 2 PRINTS 1 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 237
  • Mass: 25769
  • Checksum: D663417BA2E0E4DE
  • Sequence:
    • MVRLPLQCVL WGCLLTAVHP EPPTACREKQ YLINSQCCSL CQPGQKLVSD CTEFTETECL 
PCGESEFLDT WNRETHCHQH KYCDPNLGLR VQQKGTSETD TICTCEEGWH CTSEACESCV 
LHRSCSPGFG VKQIATGVSD TICEPCPVGF FSNVSSAFEK CHPWTSCETK DLVVQQAGTN 
KTDVVCGESW TMGPGESLGR SPGSAESPGG DPHHLRDPVC HPLGAGLYQK GGQEANQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.