Details for: CD40LG

Gene ID: 959

Symbol: CD40LG

Ensembl ID: ENSG00000102245

Description: CD40 ligand

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 48.0246
    Cell Significance Index: -7.4700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 30.2787
    Cell Significance Index: -7.6800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 19.8889
    Cell Significance Index: -8.0800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 6.0992
    Cell Significance Index: -7.5200
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 4.5616
    Cell Significance Index: 133.9700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 3.0386
    Cell Significance Index: -8.1400
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 2.0651
    Cell Significance Index: 31.9500
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 1.8341
    Cell Significance Index: 18.3900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 1.2274
    Cell Significance Index: -3.7700
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.8749
    Cell Significance Index: 9.9100
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 0.5840
    Cell Significance Index: 1.7800
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 0.5840
    Cell Significance Index: 6.0600
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.4410
    Cell Significance Index: 6.3200
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 0.0385
    Cell Significance Index: 0.2100
  • Cell Name: mature T cell (CL0002419)
    Fold Change: -0.0014
    Cell Significance Index: -0.0100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0041
    Cell Significance Index: -7.7000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0091
    Cell Significance Index: -12.3700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0094
    Cell Significance Index: -7.0800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0109
    Cell Significance Index: -8.0000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0123
    Cell Significance Index: -7.6600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0125
    Cell Significance Index: -7.9700
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -0.0128
    Cell Significance Index: -0.1200
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0164
    Cell Significance Index: -0.7100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0164
    Cell Significance Index: -0.8300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0239
    Cell Significance Index: -10.8700
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.0328
    Cell Significance Index: -0.4800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0369
    Cell Significance Index: -7.4100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0373
    Cell Significance Index: -7.4100
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0409
    Cell Significance Index: -1.6700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0434
    Cell Significance Index: -7.8300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0449
    Cell Significance Index: -7.6700
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0459
    Cell Significance Index: -0.7800
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: -0.0489
    Cell Significance Index: -0.4700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0538
    Cell Significance Index: -6.3500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0546
    Cell Significance Index: -7.9400
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: -0.0609
    Cell Significance Index: -0.5500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0650
    Cell Significance Index: -7.9900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0657
    Cell Significance Index: -8.4900
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0667
    Cell Significance Index: -1.1500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0704
    Cell Significance Index: -9.6700
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -0.0713
    Cell Significance Index: -0.9700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0742
    Cell Significance Index: -3.4900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0772
    Cell Significance Index: -7.8900
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: -0.0880
    Cell Significance Index: -0.7700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0941
    Cell Significance Index: -2.6300
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.1101
    Cell Significance Index: -1.3000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1146
    Cell Significance Index: -8.5400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1150
    Cell Significance Index: -7.7300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1199
    Cell Significance Index: -9.2000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1367
    Cell Significance Index: -8.8200
  • Cell Name: thymocyte (CL0000893)
    Fold Change: -0.1417
    Cell Significance Index: -1.7900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1436
    Cell Significance Index: -3.6900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1468
    Cell Significance Index: -3.7500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1576
    Cell Significance Index: -9.6600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1598
    Cell Significance Index: -8.3300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1641
    Cell Significance Index: -4.3900
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.1771
    Cell Significance Index: -4.2900
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: -0.1792
    Cell Significance Index: -1.8100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.1829
    Cell Significance Index: -8.2900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1880
    Cell Significance Index: -10.5500
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: -0.1890
    Cell Significance Index: -1.6100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1971
    Cell Significance Index: -10.2400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1999
    Cell Significance Index: -9.3200
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2101
    Cell Significance Index: -7.3600
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: -0.2122
    Cell Significance Index: -3.1800
  • Cell Name: monocyte-derived dendritic cell (CL0011031)
    Fold Change: -0.2171
    Cell Significance Index: -3.7300
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: -0.2335
    Cell Significance Index: -2.7600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2344
    Cell Significance Index: -10.3700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2385
    Cell Significance Index: -7.8100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2411
    Cell Significance Index: -7.6800
  • Cell Name: activated CD4-positive, alpha-beta T cell, human (CL0001043)
    Fold Change: -0.2454
    Cell Significance Index: -1.7300
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: -0.2555
    Cell Significance Index: -2.2100
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.2607
    Cell Significance Index: -7.6800
  • Cell Name: stromal cell of endometrium (CL0002255)
    Fold Change: -0.2657
    Cell Significance Index: -3.7800
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.2732
    Cell Significance Index: -8.6400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.2740
    Cell Significance Index: -7.8200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.2743
    Cell Significance Index: -7.3500
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2743
    Cell Significance Index: -10.0700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2746
    Cell Significance Index: -10.4000
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.2799
    Cell Significance Index: -3.1800
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: -0.2811
    Cell Significance Index: -2.7400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2813
    Cell Significance Index: -7.5100
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2853
    Cell Significance Index: -4.0900
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.2955
    Cell Significance Index: -7.3800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2965
    Cell Significance Index: -8.5000
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: -0.3027
    Cell Significance Index: -1.2600
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.3036
    Cell Significance Index: -7.5700
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: -0.3048
    Cell Significance Index: -2.6300
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.3083
    Cell Significance Index: -7.6900
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.3288
    Cell Significance Index: -4.3000
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.3289
    Cell Significance Index: -8.3800
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.3300
    Cell Significance Index: -6.5800
  • Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
    Fold Change: -0.3449
    Cell Significance Index: -3.1900
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: -0.3459
    Cell Significance Index: -4.0700
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.3465
    Cell Significance Index: -8.3100
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.3532
    Cell Significance Index: -7.6300
  • Cell Name: T follicular helper cell (CL0002038)
    Fold Change: -0.3537
    Cell Significance Index: -3.7500
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: -0.3577
    Cell Significance Index: -3.7800
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.3600
    Cell Significance Index: -7.6400
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.3665
    Cell Significance Index: -7.6500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Expression:** CD40LG is primarily expressed on activated CD4+ T cells, particularly alpha-beta memory T cells, T follicular helper cells, and T-helper 22 cells. 2. **Structure:** The CD40LG protein is a type II transmembrane protein, consisting of an extracellular ligand domain and a transmembrane domain. 3. **Function:** CD40LG binds to its receptor, CD40, on antigen-presenting cells, activating signaling pathways that regulate immune responses, including B cell differentiation, proliferation, and antibody production. 4. **Signaling Pathways:** The interaction between CD40LG and CD40 activates several signaling pathways, including the NF-κB pathway, which regulates the expression of genes involved in immune responses. **Pathways and Functions:** 1. **Adaptive Immune System:** CD40LG plays a critical role in the adaptive immune response, particularly in the activation of B cells and the production of antibodies. 2. **B Cell Differentiation and Proliferation:** The interaction between CD40LG and CD40 on antigen-presenting cells regulates B cell differentiation and proliferation, leading to the production of antibodies. 3. **Cytokine Signaling:** CD40LG activates signaling pathways that regulate the production of cytokines, including IL-4, IL-10, and IL-12, which are essential for immune responses. 4. **T Cell Costimulation:** CD40LG is also involved in T cell costimulation, regulating the activation and proliferation of T cells. **Clinical Significance:** 1. **Autoimmune Diseases:** Dysregulation of the CD40LG gene has been implicated in various autoimmune diseases, including rheumatoid arthritis, lupus, and multiple sclerosis. 2. **Inflammatory Diseases:** CD40LG has also been implicated in inflammatory diseases, including asthma and inflammatory bowel disease. 3. **Cancer:** The interaction between CD40LG and CD40 has been shown to regulate the activation of immune responses in cancer, highlighting the potential of targeting this pathway in cancer therapy. 4. **Immunotherapies:** Understanding the role of CD40LG in immune responses has led to the development of immunotherapies, including checkpoint inhibitors and cancer vaccines, which target the CD40LG/CD40 pathway. In conclusion, the CD40LG gene plays a critical role in regulating immune responses, including B cell differentiation, proliferation, and antibody production. Dysregulation of this gene has been implicated in various autoimmune and inflammatory diseases, highlighting the importance of this gene in maintaining immune homeostasis. Further research is needed to fully understand the mechanisms of CD40LG and its role in immune responses, with potential applications in the development of novel immunotherapies.

Genular Protein ID: 601203966

Symbol: CD40L_HUMAN

Name: CD40 ligand

UniProtKB Accession Codes:

P29965

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEMBL 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 7 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 28 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 7 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 3 RefSeq 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 1280226

Title: Cloning of TRAP, a ligand for CD40 on human T cells.

PubMed ID: 1280226

DOI: 10.1002/eji.1830221226

PubMed ID: 1385114

Title: The human T cell antigen gp39, a member of the TNF gene family, is a ligand for the CD40 receptor: expression of a soluble form of gp39 with B cell co-stimulatory activity.

PubMed ID: 1385114

DOI: 10.1002/j.1460-2075.1992.tb05530.x

PubMed ID: 7678782

Title: The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome.

PubMed ID: 7678782

DOI: 10.1016/0092-8674(93)90668-g

PubMed ID: 1281209

Title: Recombinant human CD40 ligand stimulates B cell proliferation and immunoglobulin E secretion.

PubMed ID: 1281209

DOI: 10.1084/jem.176.6.1543

PubMed ID: 7678552

Title: Human CD40-ligand: molecular cloning, cellular distribution and regulation of expression by factors controlling IgE production.

PubMed ID: 7678552

DOI: 10.1016/0014-5793(93)81175-y

PubMed ID: 7999797

Title: Structural organization of the gene for CD40 ligand: molecular analysis for diagnosis of X-linked hyper-IgM syndrome.

PubMed ID: 7999797

DOI: 10.1016/0167-4781(94)00179-7

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8626375

Title: Human native soluble CD40L is a biologically active trimer, processed inside microsomes.

PubMed ID: 8626375

DOI: 10.1074/jbc.271.11.5965

PubMed ID: 8617933

Title: Cross-linking of the CD40 ligand on human CD4+ T lymphocytes generates a costimulatory signal that up-regulates IL-4 synthesis.

PubMed ID: 8617933

PubMed ID: 11676606

Title: Determination of carbohydrate structures N-linked to soluble CD154 and characterization of the interactions of CD40 with CD154 expressed in Pichia pastoris and Chinese hamster ovary cells.

PubMed ID: 11676606

DOI: 10.1006/prep.2001.1501

PubMed ID: 15193700

Title: Release of soluble CD40L from platelets is regulated by glycoprotein IIb/IIIa and actin polymerization.

PubMed ID: 15193700

DOI: 10.1016/j.jacc.2003.12.055

PubMed ID: 15067037

Title: The modulation of CD40 ligand signaling by transmembrane CD28 splice variant in human T cells.

PubMed ID: 15067037

DOI: 10.1084/jem.20031705

PubMed ID: 31331973

Title: Integrin Binding to the Trimeric Interface of CD40L Plays a Critical Role in CD40/CD40L Signaling.

PubMed ID: 31331973

DOI: 10.4049/jimmunol.1801630

PubMed ID: 8589998

Title: 2-A crystal structure of an extracellular fragment of human CD40 ligand.

PubMed ID: 8589998

DOI: 10.1016/s0969-2126(01)00239-8

PubMed ID: 9605317

Title: The role of polar interactions in the molecular recognition of CD40L with its receptor CD40.

PubMed ID: 9605317

DOI: 10.1002/pro.5560070506

PubMed ID: 7679206

Title: Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM.

PubMed ID: 7679206

DOI: 10.1038/361539a0

PubMed ID: 8094231

Title: CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM.

PubMed ID: 8094231

DOI: 10.1038/361541a0

PubMed ID: 7679801

Title: CD40 ligand gene defects responsible for X-linked hyper-IgM syndrome.

PubMed ID: 7679801

DOI: 10.1126/science.7679801

PubMed ID: 7717401

Title: Characterization of nine novel mutations in the CD40 ligand gene in patients with X-linked hyper IgM syndrome of various ancestry.

PubMed ID: 7717401

PubMed ID: 7532185

Title: Signaling through CD40 rescues IgE but not IgG or IgA secretion in X-linked immunodeficiency with hyper-IgM.

PubMed ID: 7532185

DOI: 10.1172/jci117692

PubMed ID: 8889581

Title: Mutation analysis in CD40 ligand deficiency leading to X-linked hypogammaglobulinemia with hyper IgM syndrome.

PubMed ID: 8889581

DOI: 10.1002/(sici)1098-1004(1996)8:3<223::aid-humu5>3.0.co;2-a

PubMed ID: 8550833

Title: A single strand conformation polymorphism study of CD40 ligand. Efficient mutation analysis and carrier detection for X-linked hyper IgM syndrome.

PubMed ID: 8550833

DOI: 10.1172/jci118389

PubMed ID: 9150729

Title: Mutations of the CD40 ligand gene in 13 Japanese patients with X-linked hyper-IgM syndrome.

PubMed ID: 9150729

DOI: 10.1007/s004390050417

PubMed ID: 9746782

Title: Mutations of the CD40 ligand gene and its effect on CD40 ligand expression in patients with X-linked hyper IgM syndrome.

PubMed ID: 9746782

PubMed ID: 26545377

Title: Novel and recurrent AID mutations underlie prevalent autosomal recessive form of HIGM in consanguineous patients.

PubMed ID: 26545377

DOI: 10.1007/s00251-015-0878-6

Sequence Information:

  • Length: 261
  • Mass: 29274
  • Checksum: 16F5CEB093BCC2BB
  • Sequence:
    • MIETYNQTSP RSAATGLPIS MKIFMYLLTV FLITQMIGSA LFAVYLHRRL DKIEDERNLH 
EDFVFMKTIQ RCNTGERSLS LLNCEEIKSQ FEGFVKDIML NKEETKKENS FEMQKGDQNP 
QIAAHVISEA SSKTTSVLQW AEKGYYTMSN NLVTLENGKQ LTVKRQGLYY IYAQVTFCSN 
REASSQAPFI ASLCLKSPGR FERILLRAAN THSSAKPCGQ QSIHLGGVFE LQPGASVFVN 
VTDPSQVSHG TGFTSFGLLK L

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.