Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 401.9410
Cell Significance Index: -62.5200 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 278.3436
Cell Significance Index: -70.6000 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 211.5439
Cell Significance Index: -87.1500 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 180.4030
Cell Significance Index: -73.2900 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 179.5296
Cell Significance Index: -84.7600 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 161.1730
Cell Significance Index: -82.9100 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 126.4191
Cell Significance Index: -84.8300 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 77.6439
Cell Significance Index: -74.1300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 64.7955
Cell Significance Index: -79.8900 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 25.2682
Cell Significance Index: -77.6100 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 24.8651
Cell Significance Index: -66.6100 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 21.3277
Cell Significance Index: -84.1600 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 13.9542
Cell Significance Index: -30.5400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 3.2150
Cell Significance Index: 151.1000 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 3.1374
Cell Significance Index: 37.4000 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 3.0104
Cell Significance Index: 51.5900 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.6223
Cell Significance Index: 526.0300 - Cell Name: cell in vitro (CL0001034)
Fold Change: 2.4628
Cell Significance Index: 1344.9700 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 2.2167
Cell Significance Index: 139.7100 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.9187
Cell Significance Index: 123.7900 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.5893
Cell Significance Index: 74.1000 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 1.5397
Cell Significance Index: 45.2200 - Cell Name: peg cell (CL4033014)
Fold Change: 1.4452
Cell Significance Index: 33.3900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.2952
Cell Significance Index: 464.5800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.2688
Cell Significance Index: 33.8800 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 1.2290
Cell Significance Index: 22.7200 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.0865
Cell Significance Index: 140.3700 - Cell Name: granulosa cell (CL0000501)
Fold Change: 1.0823
Cell Significance Index: 28.4600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 1.0689
Cell Significance Index: 59.9800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 1.0521
Cell Significance Index: 39.8400 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.9345
Cell Significance Index: 26.1200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.9311
Cell Significance Index: 114.4900 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.9287
Cell Significance Index: 109.5200 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.9023
Cell Significance Index: 39.9100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.8599
Cell Significance Index: 52.8600 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.7785
Cell Significance Index: 52.3500 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.6736
Cell Significance Index: 121.4300 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.6657
Cell Significance Index: 294.3100 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.6408
Cell Significance Index: 33.2900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.6203
Cell Significance Index: 100.8900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.5673
Cell Significance Index: 392.3900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.3782
Cell Significance Index: 28.1900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.3268
Cell Significance Index: 7.0800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2801
Cell Significance Index: 8.0700 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.1932
Cell Significance Index: 24.7700 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.1396
Cell Significance Index: 3.8000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.1005
Cell Significance Index: 17.1600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0755
Cell Significance Index: 142.1300 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0694
Cell Significance Index: 52.5100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0679
Cell Significance Index: 125.2300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0448
Cell Significance Index: 1.5800 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0292
Cell Significance Index: 13.2500 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.0243
Cell Significance Index: 2.4000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0096
Cell Significance Index: 14.7200 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0192
Cell Significance Index: -3.8100 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0212
Cell Significance Index: -13.4800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0243
Cell Significance Index: -3.3400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0370
Cell Significance Index: -27.1000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0419
Cell Significance Index: -1.9000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0423
Cell Significance Index: -2.2200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0461
Cell Significance Index: -34.1500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0588
Cell Significance Index: -79.9500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0633
Cell Significance Index: -4.8500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: -0.0649
Cell Significance Index: -12.3500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0755
Cell Significance Index: -42.6000 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0833
Cell Significance Index: -52.0200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1264
Cell Significance Index: -12.9100 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.2090
Cell Significance Index: -4.0800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.2269
Cell Significance Index: -16.0500 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2274
Cell Significance Index: -47.8900 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2554
Cell Significance Index: -73.4800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2847
Cell Significance Index: -33.1800 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.3106
Cell Significance Index: -7.4500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.3456
Cell Significance Index: -50.2400 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.3541
Cell Significance Index: -21.2600 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.3848
Cell Significance Index: -11.0300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.4052
Cell Significance Index: -46.4200 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.4247
Cell Significance Index: -10.8500 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.4985
Cell Significance Index: -14.2300 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.6093
Cell Significance Index: -19.5200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.6993
Cell Significance Index: -72.8100 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.7432
Cell Significance Index: -4.4900 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.7698
Cell Significance Index: -87.8800 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.8487
Cell Significance Index: -44.2100 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.8990
Cell Significance Index: -11.1500 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: -0.9554
Cell Significance Index: -14.5100 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.9821
Cell Significance Index: -77.7800 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: -1.1098
Cell Significance Index: -6.8300 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -1.1925
Cell Significance Index: -29.8100 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -1.1980
Cell Significance Index: -20.0500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.3660
Cell Significance Index: -83.7500 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -1.4090
Cell Significance Index: -37.6900 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -1.4333
Cell Significance Index: -30.4200 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -1.4905
Cell Significance Index: -47.4700 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -1.5426
Cell Significance Index: -50.5100 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: -1.5867
Cell Significance Index: -12.2300 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -1.6269
Cell Significance Index: -41.8200 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -1.7879
Cell Significance Index: -62.1300 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -1.8483
Cell Significance Index: -64.7500 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -1.9406
Cell Significance Index: -41.4800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1440314806
Symbol: CD47_HUMAN
Name: Leukocyte surface antigen CD47
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1394148
Title: An ovarian tumor marker with homology to vaccinia virus contains an IgV-like region and multiple transmembrane domains.
PubMed ID: 1394148
PubMed ID: 7691831
Title: Molecular cloning of integrin-associated protein: an immunoglobulin family member with multiple membrane spanning domains implicated in alpha-v beta-3-dependent ligand binding.
PubMed ID: 7691831
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7998989
Title: Isolation and characterization of CD47 glycoprotein: a multispanning membrane protein which is the same as integrin-associated protein (IAP) and the ovarian tumour marker OA3.
PubMed ID: 7998989
DOI: 10.1042/bj3040525
PubMed ID: 8550562
Title: Integrin-associated protein is a receptor for the C-terminal domain of thrombospondin.
PubMed ID: 8550562
DOI: 10.1074/jbc.271.1.21
PubMed ID: 10549293
Title: Ubiquitin-related proteins regulate interaction of vimentin intermediate filaments with the plasma membrane.
PubMed ID: 10549293
PubMed ID: 11454874
Title: Normal ligand binding and signaling by CD47 (integrin-associated protein) requires a long range disulfide bond between the extracellular and membrane-spanning domains.
PubMed ID: 11454874
PubMed ID: 11509594
Title: Bidirectional negative regulation of human T and dendritic cells by CD47 and its cognate receptor signal-regulator protein-alpha: down-regulation of IL-12 responsiveness and inhibition of dendritic cell activation.
PubMed ID: 11509594
PubMed ID: 15383453
Title: Adhesion of human T cells to antigen-presenting cells through SIRPbeta2-CD47 interaction costimulates T-cell proliferation.
PubMed ID: 15383453
PubMed ID: 15917238
PubMed ID: 19004835
Title: Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses.
PubMed ID: 19004835
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 19349973
Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.
PubMed ID: 19349973
DOI: 10.1038/nbt.1532
PubMed ID: 22079249
Title: Integrin-associated protein (CD47) is a putative mediator for soluble fibrinogen interaction with human red blood cells membrane.
PubMed ID: 22079249
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 27742621
Title: TSP1-CD47 signaling is upregulated in clinical pulmonary hypertension and contributes to pulmonary arterial vasculopathy and dysfunction.
PubMed ID: 27742621
DOI: 10.1093/cvr/cvw218
PubMed ID: 32679764
Title: CD47 Promotes Age-Associated Deterioration in Angiogenesis, Blood Flow and Glucose Homeostasis.
PubMed ID: 32679764
DOI: 10.3390/cells9071695
PubMed ID: 18657508
Title: Paired receptor specificity explained by structures of signal regulatory proteins alone and complexed with CD47.
PubMed ID: 18657508
Sequence Information:
- Length: 323
- Mass: 35214
- Checksum: 5D20730A2632D550
- Sequence:
MWPLVAALLL GSACCGSAQL LFNKTKSVEF TFCNDTVVIP CFVTNMEAQN TTEVYVKWKF KGRDIYTFDG ALNKSTVPTD FSSAKIEVSQ LLKGDASLKM DKSDAVSHTG NYTCEVTELT REGETIIELK YRVVSWFSPN ENILIVIFPI FAILLFWGQF GIKTLKYRSG GMDEKTIALL VAGLVITVIV IVGAILFVPG EYSLKNATGL GLIVTSTGIL ILLHYYVFST AIGLTSFVIA ILVIQVIAYI LAVVGLSLCI AACIPMHGPL LISGLSILAL AQLLGLVYMK FVASNQKTIQ PPRKAVEEPL NAFKESKGMM NDE
Genular Protein ID: 272715215
Symbol: A0A0A1TSG4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 293
- Mass: 31872
- Checksum: E841A2F6696D11F4
- Sequence:
MWPLVAALLL GSACCGSAQL LFNKTKSVEF TFCNDTVVIP CFVTNMEAQN TTEVYVKWKF KGRDIYTFDG ALNKSTVPTD FSSAKIEVSQ LLKGDASLKM DKSDAVSHTG NYTCEVTELT REGETIIELK YRVVSWFSPN ENILIVIFPI FAILLFWGQF GIKTLKYRSG GMDEKTIALL VAGLVITVIV IVGAILFVPG EYSLKNATGL GLIVTSTGIL ILLHYYVFST AIGLTSFVIA ILVIQVIAYI LAVVGLSLCI AACIPMHGPL LISGLSILAL AQLLGLVYMK FVE
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.