Details for: MTRF1
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: mural cell (CL0008034)
Fold Change: 1.47
Marker Score: 169,071 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,782 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,007 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.99
Marker Score: 5,926 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,404 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.95
Marker Score: 491 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,408 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.94
Marker Score: 445 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 0.91
Marker Score: 1,408 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,726 - Cell Name: germ cell (CL0000586)
Fold Change: 0.91
Marker Score: 1,587 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.89
Marker Score: 5,079 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,295 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.86
Marker Score: 311 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,266 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.75
Marker Score: 575 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.75
Marker Score: 11,761 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.74
Marker Score: 381 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.73
Marker Score: 889 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.73
Marker Score: 983 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.73
Marker Score: 6,275 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.71
Marker Score: 7,285 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.7
Marker Score: 281 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.7
Marker Score: 1,421 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.7
Marker Score: 2,931 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.7
Marker Score: 42,765 - Cell Name: brush cell (CL0002204)
Fold Change: 0.69
Marker Score: 626 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 0.68
Marker Score: 6,476 - Cell Name: gut endothelial cell (CL0000131)
Fold Change: 0.67
Marker Score: 240 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.66
Marker Score: 170 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.65
Marker Score: 1,526 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 0.61
Marker Score: 5,722 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 0.58
Marker Score: 245 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.57
Marker Score: 341 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 0.55
Marker Score: 20,252 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.54
Marker Score: 434 - Cell Name: neuron (CL0000540)
Fold Change: 0.53
Marker Score: 2,164 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.51
Marker Score: 298 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.51
Marker Score: 139 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.51
Marker Score: 558 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.49
Marker Score: 1,912 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.49
Marker Score: 311 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 0.49
Marker Score: 389 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.48
Marker Score: 319 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.47
Marker Score: 1,167 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 0.46
Marker Score: 577 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.46
Marker Score: 1,920 - Cell Name: male germ cell (CL0000015)
Fold Change: 0.43
Marker Score: 123 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.43
Marker Score: 628 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.42
Marker Score: 147 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.42
Marker Score: 8,970 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 0.42
Marker Score: 15,867 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 0.41
Marker Score: 1,459 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.41
Marker Score: 898 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 0.39
Marker Score: 230 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.39
Marker Score: 127 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 0.39
Marker Score: 5,848 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 0.39
Marker Score: 2,978 - Cell Name: proerythroblast (CL0000547)
Fold Change: 0.39
Marker Score: 263 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 0.38
Marker Score: 8,473 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 0.38
Marker Score: 119 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.38
Marker Score: 254 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 0.37
Marker Score: 7,427 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 0.37
Marker Score: 280 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.37
Marker Score: 357 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.37
Marker Score: 97 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.37
Marker Score: 362 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 0.36
Marker Score: 244 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.36
Marker Score: 106 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 0.36
Marker Score: 1,487 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.36
Marker Score: 113 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.36
Marker Score: 359 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.36
Marker Score: 384 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.35
Marker Score: 400 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.35
Marker Score: 322 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.35
Marker Score: 183 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.34
Marker Score: 139 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.33
Marker Score: 2,143 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.33
Marker Score: 288 - Cell Name: oogonial cell (CL0000024)
Fold Change: 0.33
Marker Score: 473 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.33
Marker Score: 103 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 0.33
Marker Score: 1,409 - Cell Name: erythroblast (CL0000765)
Fold Change: 0.32
Marker Score: 201 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.32
Marker Score: 5,714 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 0.32
Marker Score: 875 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.32
Marker Score: 152 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 0.31
Marker Score: 1,163 - Cell Name: Schwann cell (CL0002573)
Fold Change: 0.31
Marker Score: 108 - Cell Name: basal cell (CL0000646)
Fold Change: 0.31
Marker Score: 401 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.31
Marker Score: 919 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 0.31
Marker Score: 150 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.3
Marker Score: 114 - Cell Name: oocyte (CL0000023)
Fold Change: 0.3
Marker Score: 75 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 0.3
Marker Score: 803 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 0.3
Marker Score: 164 - Cell Name: hepatoblast (CL0005026)
Fold Change: 0.3
Marker Score: 974 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.29
Marker Score: 119 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.29
Marker Score: 350 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.29
Marker Score: 491 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.29
Marker Score: 408
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1895625411
Symbol: RF1M_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9838146
Title: Identification and cloning of human mitochondrial translational release factor 1 and the ribosome recycling factor.
PubMed ID: 9838146
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15057823
Title: The DNA sequence and analysis of human chromosome 13.
PubMed ID: 15057823
DOI: 10.1038/nature02379
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17803939
Title: mtRF1a is a human mitochondrial translation release factor decoding the major termination codons UAA and UAG.
PubMed ID: 17803939
PubMed ID: 22569235
Title: Structure based hypothesis of a mitochondrial ribosome rescue mechanism.
PubMed ID: 22569235
PubMed ID: 36302763
Title: Human mtRF1 terminates COX1 translation and its ablation induces mitochondrial ribosome-associated quality control.
PubMed ID: 36302763
PubMed ID: 35260756
Title: Mammalian HEMK1 methylates glutamine residue of the GGQ motif of mitochondrial release factors.
PubMed ID: 35260756
PubMed ID: 36596788
Title: Human mitochondria require mtRF1 for translation termination at non-canonical stop codons.
PubMed ID: 36596788
PubMed ID: 37141370
Title: Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
PubMed ID: 37141370
Sequence Information:
- Length: 445
- Mass: 52306
- Checksum: 3DC637D90F04C6F7
- Sequence:
MNRHLCVWLF RHPSLNGYLQ CHIQLHSHQF RQIHLDTRLQ VFRQNRNCIL HLLSKNWSRR YCHQDTKMLW KHKALQKYME NLSKEYQTLE QCLQHIPVNE ENRRSLNRRH AELAPLAAIY QEIQETEQAI EELESMCKSL NKQDEKQLQE LALEERQTID QKINMLYNEL FQSLVPKEKY DKNDVILEVT AGRTTGGDIC QQFTREIFDM YQNYSCYKHW QFELLNYTPA DYGGLHHAAA RISGDGVYKH LKYEGGIHRV QRIPEVGLSS RMQRIHTGTM SVIVLPQPDE VDVKLDPKDL RIDTFRAKGA GGQHVNKTDS AVRLVHIPTG LVVECQQERS QIKNKEIAFR VLRARLYQQI IEKDKRQQQS ARKLQVGTRA QSERIRTYNF TQDRVSDHRI AYEVRDIKEF LCGGKGLDQL IQRLLQSADE EAIAELLDEH LKSAK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.