Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 132.9517
Cell Significance Index: -20.6800 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 84.3801
Cell Significance Index: -34.2800 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 68.5478
Cell Significance Index: -35.2600 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 63.3172
Cell Significance Index: -16.0600 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 55.4305
Cell Significance Index: -26.1700 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 16.4888
Cell Significance Index: -20.3300 - Cell Name: hepatic pit cell (CL2000054)
Fold Change: 10.5342
Cell Significance Index: 28.2200 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 8.6246
Cell Significance Index: -26.4900 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 6.9606
Cell Significance Index: 128.6500 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 5.6132
Cell Significance Index: -22.1500 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 5.4597
Cell Significance Index: 160.3500 - Cell Name: T-helper 22 cell (CL0001042)
Fold Change: 4.6822
Cell Significance Index: 14.2700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 3.9660
Cell Significance Index: 99.1400 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 3.7843
Cell Significance Index: 37.9500 - Cell Name: IgG-negative class switched memory B cell (CL0002117)
Fold Change: 3.7791
Cell Significance Index: 16.9000 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.2514
Cell Significance Index: 147.5800 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.1302
Cell Significance Index: 24.4900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.0217
Cell Significance Index: 65.9200 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 1.0124
Cell Significance Index: 192.6700 - Cell Name: IgG memory B cell (CL0000979)
Fold Change: 0.8113
Cell Significance Index: 4.9000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.7383
Cell Significance Index: 73.0300 - Cell Name: late promyelocyte (CL0002151)
Fold Change: 0.7205
Cell Significance Index: 4.7800 - Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
Fold Change: 0.7043
Cell Significance Index: 6.1600 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.6728
Cell Significance Index: 2.8000 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.6674
Cell Significance Index: 602.6600 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.4757
Cell Significance Index: 12.7300 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 0.3448
Cell Significance Index: 1.8800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.3337
Cell Significance Index: 54.2700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: 0.3155
Cell Significance Index: 66.4600 - Cell Name: DN1 thymic pro-T cell (CL0000894)
Fold Change: 0.2831
Cell Significance Index: 2.9400 - Cell Name: early promyelocyte (CL0002154)
Fold Change: 0.1942
Cell Significance Index: 1.2400 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.1274
Cell Significance Index: 13.8600 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.0350
Cell Significance Index: 21.8800 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: 0.0171
Cell Significance Index: 0.2500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0040
Cell Significance Index: -3.0000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0049
Cell Significance Index: -9.1500 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0105
Cell Significance Index: -0.3700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0140
Cell Significance Index: -25.9000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0173
Cell Significance Index: -26.5600 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0196
Cell Significance Index: -26.6300 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0197
Cell Significance Index: -1.0000 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0211
Cell Significance Index: -11.9000 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -0.0220
Cell Significance Index: -0.3800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0222
Cell Significance Index: -0.6400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0234
Cell Significance Index: -17.7000 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.0399
Cell Significance Index: -1.0200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0496
Cell Significance Index: -36.3900 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.0543
Cell Significance Index: -3.7600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0563
Cell Significance Index: -35.7500 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0573
Cell Significance Index: -25.3300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0618
Cell Significance Index: -2.8000 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0666
Cell Significance Index: -23.8900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0693
Cell Significance Index: -31.4500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0776
Cell Significance Index: -13.2500 - Cell Name: leukocyte (CL0000738)
Fold Change: -0.0818
Cell Significance Index: -1.3900 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0919
Cell Significance Index: -3.7700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.1036
Cell Significance Index: -20.5600 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1057
Cell Significance Index: -30.4200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.1134
Cell Significance Index: -22.7400 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1356
Cell Significance Index: -13.8600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1384
Cell Significance Index: -15.8600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1401
Cell Significance Index: -8.5900 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.1412
Cell Significance Index: -6.1400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.1542
Cell Significance Index: -27.8100 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.1671
Cell Significance Index: -22.9500 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.1799
Cell Significance Index: -20.5400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1920
Cell Significance Index: -19.9900 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.1960
Cell Significance Index: -25.1300 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.2143
Cell Significance Index: -3.2300 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.2276
Cell Significance Index: -27.9800 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.2300
Cell Significance Index: -29.7200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.2427
Cell Significance Index: -35.2800 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.2723
Cell Significance Index: -12.8000 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.3180
Cell Significance Index: -19.0900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.3308
Cell Significance Index: -25.3900 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.3464
Cell Significance Index: -11.1000 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.3573
Cell Significance Index: -25.2700 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.3672
Cell Significance Index: -24.6900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.3998
Cell Significance Index: -29.8000 - Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
Fold Change: -0.4105
Cell Significance Index: -3.8400 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: -0.4235
Cell Significance Index: -4.3900 - Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
Fold Change: -0.4236
Cell Significance Index: -3.5800 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.4273
Cell Significance Index: -22.2000 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.4598
Cell Significance Index: -28.2600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.4621
Cell Significance Index: -25.9300 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.4631
Cell Significance Index: -36.6800 - Cell Name: lymphocyte (CL0000542)
Fold Change: -0.4965
Cell Significance Index: -6.7600 - Cell Name: myeloid leukocyte (CL0000766)
Fold Change: -0.5012
Cell Significance Index: -4.0600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.5353
Cell Significance Index: -24.9600 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: -0.5693
Cell Significance Index: -11.1300 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.6038
Cell Significance Index: -12.8600 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.6086
Cell Significance Index: -26.9200 - Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
Fold Change: -0.6376
Cell Significance Index: -4.9600 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.6486
Cell Significance Index: -22.7200 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.6527
Cell Significance Index: -34.0000 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.6573
Cell Significance Index: -18.3700 - Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
Fold Change: -0.6750
Cell Significance Index: -6.4000 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.7071
Cell Significance Index: -23.1500 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.7098
Cell Significance Index: -26.8800 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: -0.7110
Cell Significance Index: -11.0000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 89854198
Symbol: CD48_HUMAN
Name: CD48 antigen
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1999351
PubMed ID: 1999350
Title: The human leucocyte antigen CD48 (MEM-102) is closely related to the activation marker Blast-1.
PubMed ID: 1999350
DOI: 10.1007/bf00210823
PubMed ID: 2828034
Title: Molecular cloning of the lymphocyte activation marker Blast-1.
PubMed ID: 2828034
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1847502
Title: Characterization of the Epstein-Barr virus-inducible gene encoding the human leukocyte adhesion and activation antigen BLAST-1 (CD48).
PubMed ID: 1847502
PubMed ID: 1827826
Title: TCT.1, a target molecule for gamma/delta T cells, is encoded by an immunoglobulin superfamily gene (Blast-1) located in the CD1 region of human chromosome 1.
PubMed ID: 1827826
PubMed ID: 9418191
Title: Detection of a soluble form of the leukocyte surface antigen CD48 in plasma and its elevation in patients with lymphoid leukemias and arthritis.
PubMed ID: 9418191
PubMed ID: 9041467
Title: Both human alpha/beta and gamma interferons upregulate the expression of CD48 cell surface molecules.
PubMed ID: 9041467
PubMed ID: 9893294
Title: CD48 expression on leukocytes in infectious diseases: flow cytometric analysis of surface antigen.
PubMed ID: 9893294
PubMed ID: 9841922
Title: 2B4, the natural killer and T cell immunoglobulin superfamily surface protein, is a ligand for CD48.
PubMed ID: 9841922
PubMed ID: 12007789
Title: The oxygen-substituted palmitic acid analogue, 13-oxypalmitic acid, inhibits Lck localization to lipid rafts and T cell signaling.
PubMed ID: 12007789
PubMed ID: 19349973
Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.
PubMed ID: 19349973
DOI: 10.1038/nbt.1532
PubMed ID: 19494291
Title: Sequential cooperation of CD2 and CD48 in the buildup of the early TCR signalosome.
PubMed ID: 19494291
PubMed ID: 27249817
Title: Modulation of natural killer cell functions by interactions between 2B4 and CD48 in cis and in trans.
PubMed ID: 27249817
DOI: 10.1098/rsob.160010
Sequence Information:
- Length: 243
- Mass: 27683
- Checksum: 9E46D76FC36A512C
- Sequence:
MCSRGWDSCL ALELLLLPLS LLVTSIQGHL VHMTVVSGSN VTLNISESLP ENYKQLTWFY TFDQKIVEWD SRKSKYFESK FKGRVRLDPQ SGALYISKVQ KEDNSTYIMR VLKKTGNEQE WKIKLQVLDP VPKPVIKIEK IEDMDDNCYL KLSCVIPGES VNYTWYGDKR PFPKELQNSV LETTLMPHNY SRCYTCQVSN SVSSKNGTVC LSPPCTLARS FGVEWIASWL VVTVPTILGL LLT
Genular Protein ID: 3189685683
Symbol: A0A087X1S7_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
Sequence Information:
- Length: 252
- Mass: 28855
- Checksum: 897220C3C065C048
- Sequence:
MCSRGWDSCL ALELLLLPLS LLVTSIQGHL VHMTVVSGSN VTLNISESLP ENYKQLTWFY TFDQKIVEWD SRKSKYFESK FKGRVRLDPQ SGALYISKVQ KEDNSTYIMR VLKKTGNEQE WKIKLQVLDP VPKPVIKIEK IEDMDDNCYL KLSCVIPGES VNYTWYGDKR PFPKELQNSV LETTLMPHNY SRCYTCQVSN SVSSKNGTVC LSPPCTLGKK DPWELRGAQG NWSCFEQRKA GGPIQPPCTV WW
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.